Glycopolypeptide gold nanoparticles and preparation method and application thereof

Abstract

The invention provides glycopolypeptide gold nanoparticles and a preparation method and application thereof. The preparation method of the glycopolypeptide gold nanoparticles comprises the following steps: adding glycopolypeptide into a NaOH aqueous solution with the pH value of 12, uniformly stirring to obtain a mixed solution A, heating the mixed solution A to 70-90 DEG C under a water bath condition, dropwise adding a chloroauric acid aqueous solution under a stirring condition to obtain a mixed solution B, and gradually changing the mixed solution B from original faint yellow to wine red after 30-50 minutes to obtain the glycopolypeptide gold nanoparticles. The carboxyl functionalized gold nanoparticles are obtained through one-step reduction of glycopolypeptide, the process of preparing the gold nanoparticles can be greatly simplified, meanwhile, detection of various metal ions is achieved through the gold nanoparticles, the detection speed is high, and the detection method is simple and convenient.

Description

technical field [0001] The invention relates to the technical field of functionalized gold nanoparticles, in particular to a glycopolypeptide gold nanoparticle and its preparation method and application. Background technique [0002] At present, the common traditional heavy metal ion detection methods include the following methods: atomic fluorescence spectrometry, atomic absorption spectrometry, inductively coupled plasma emission spectrometry and other methods, but all of the above methods require large and expensive instruments, and the operation procedures are complicated. The time is still relatively long, it is difficult to quickly detect heavy metal ions. In order to overcome the above problems, many scholars are actively developing new instant and rapid detection methods. Among them, the colorimetric detection method of carboxyl or amino functionalized gold nano-ions to detect heavy metal ions, because of its instantaneity, has triggered many scholars in this regard....

AI Technical Summary

Problems solved by technology

[0003] However, most of the current functionalized nanoparticles are prepared using a two-step method, that is, first using sodium borohydride as a reducing agent to reduce chloroauric acid to obtain gold nanoparticles, and then Reacting gold nanoparticles with substances with special functional groups such as carboxyl or amino groups to achieve their functionalization, the above methods are cumbersome and complicated

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