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72 results about "Muscone" patented technology

Muscone is an organic compound that is the primary contributor to the odor of musk. The chemical structure of muscone was first elucidated by Lavoslav Ružička. It consists of a 15-membered ring ketone with one methyl substituent in the 3-position. It is an oily liquid that is found naturally as the (−)-enantiomer, (R)-3-methylcyclopentadecanone. Muscone has been synthesized as the pure (−)-enantiomer as well as the racemate. It is very slightly soluble in water and miscible with alcohol.

Quality testing method for fingerprint of herbal medicine musk

The invention discloses a quality testing method for fingerprint of herbal medicine musk. The method includes establishing a gas chromatographic fingerprint of the musk by gas chromatography, and analyzing chemical components of different types of musk by gas chromatography and mass spectrometry. A test sample is processed by specific process, chromatographic detection is optimized, and tests show that the method is stable, precise and repeatable. Three established reference musk fingerprints are well specific. Similarity of the three types of musk is researched under integration of non-integration conditions of muscone, and more accurate basis is provided for testing quality of the three different types of musk. In addition, common compounds of the three types of musk are obtained by identification by GC-MS (gas chromatography and mass spectrometry) and can be used as basis for further identification of synthetic musk, domestic musk and natural musk.
Owner:ZHANGZHOU PIEN TZE HUANG PHARM

Original flavor yoghourt perfume formulation

The invention discloses a formula of a plain yogurt essence, which mainly comprises ingredients of propanediol, lactic acid, butanedione, stabilizing agent, maltol, vanilline, acetyl methyl carbinol, ethyl lactate, ethyl laurate, and the like. The formula takes the yogurt zymotic fluid and the yogurt muscone that have a strong affinity to milk products and are natural ingredients as stabilizing agent. In the invention, the plain yogurt essence is used an additive, thus enhancing the fermentation of final products of acidified milk and acidified milk drinks and providing natural flavor. Heat resisting property and fragrance quality are higher than the other domestic essence products of the same kind.
Owner:SHANGHAI BAIRUN INVESTMENT HLDG GRP CO LTD

Asymmetric induction catalytic synthesis method for L-muscone

The invention discloses an asymmetric induction catalytic synthesis method for L-muscone. The L-muscone is prepared by performing asymmetric induction catalytic synthesis on N-3-methyl-cyclopentadecane alkenyl benzylamine which is obtained by asymmetrically converting a racemate compound for multiple times and used as raw materials in the presence of an organo-transition metal complex inducing catalyst. The method has the prominent advantages of high economic benefit, simple synthesis process and low synthesis temperature.
Owner:DALIAN ZHAOYI BIOLOGY KETONE TECH

Continuous preparation method of DL-muscone

The invention discloses a continuous preparation method of DL-muscone. The preparation method comprises the following steps: 1) dissolving 2,15-hexadecanedione diketone in an aprotic solvent, then carrying out a continuous reaction in a fixed-bed cyclization reactor for generating a 3-methylcyclopentanone analogue under the action of a cyclization catalyst; 2) carrying out desolvation on the 3-methylcyclopentanone analogue, dissolving the obtained product in a protic solvent, then carrying out a continuous reaction with hydrogen in a fixed-bed hydrogenation reactor under the action of a hydrogenation catalyst to obtain muscone; and 3) carrying out desolvation on the product obtained in the step 2), carrying out continuous chromatographic separation, and carrying out desolvation on the product liquid containing the DL-muscone to obtain the DL-muscone product. The method for preparing the DL-muscone provided by the invention has high process stability and high product yield, continuous production of the DL-muscone can be realized, the production cost is greatly reduced, and the effective capacity of a device is improved.
Owner:INST OF CHEM ENG GUANGDONG ACAD OF SCI

Medicinal composition used for treating fatty liver and quality detection method thereof

ActiveCN102692477AReduce cholesterolReduce the content of lipid peroxidation products (MDA)Component separationDigestive systemEthyl acetateMethanol
The invention discloses a quality detection method of medicinal composition used for treating fatty liver. Raw materials are screened, the identified medicinal materials are selected, a determination and identification method adopts a thin layer chromatography test, ethyl acetate-methyl alcohol-water (20: 2: 1) is taken as a developer, and experimental results show that sample spots are clear, separation effect is good and no interference is produced in negative control. The raw materials of the medicinal composition are as follows in parts by weight: 50-250 parts of oriental wormwood, 40-200 parts of rough gentian, 15-85 parts of jasmine, 3-18 parts of rheum offcinale, 10-50 parts of white paeony root, 10-50 parts of liquorice, 14-70 parts of pseudo ginseng, 1-6 parts of snake gall, 1-4 parts of bezoar and 0.5-2.5 parts of muscone.
Owner:ZHANGZHOU PIEN TZE HUANG PHARM

Method for determining content of musk ketone in artificial musk

InactiveCN103163259ASimple and reliable method for determining muscone content in artificial muskConducive to industrial mass productionComponent separationCapillary gas chromatographyMusk ketone
The invention provides a method for determining the content of musk ketone in artificial musk, and the method comprises the following steps: step 1, preparing the solution of an artificial musk test sample and musk ketone reference solutions; step 2, by using a capillary gas chromatography, assaying the reference solutions to acquire a standard curve; and step 3, determining the content of musk ketone in the artificial musk test sample according to the standard curve. The method for determining the content of musk ketone in artificial musk of the present invention is simple and reliable, thus being suitable for industrial mass production.
Owner:上海永太医药科技有限公司

Muscone suppository and preparation method and application thereof

InactiveCN107951836AReduce the size of the ulcerImprove local symptomsOrganic active ingredientsSuppositories deliveryGynecologyPEG 400
The invention discloses a muscone suppository and a preparation method and application thereof. The muscone suppository is prepared from distilled water, PEG 4000, PEG 400, Tween-80, glyceryl monostearate and muscone. The muscone suppository is used for treating haemorrhoids, directly acts on an affected area and takes effect quickly, the first-pass effect of the liver is avoided at the same time,and the bioavailability of the muscone suppository is improved.
Owner:山东宏济堂制药集团股份有限公司

Method for detecting synthetic musk

The invention discloses a method for detecting synthetic musk. Muscone, 4-methyl-cyclopentadecanon, musk lactone, dehydrogenated musk lactone and C18H2803 of synthetic musk in a medicine are qualitatively detected, so as to judge whether the medical synthetic musk conforming to the regulations of the pharmacopeia is used in the medicine. Through the method, the safety and effectiveness of the medicine can be judged accurately, and the medicine quality is controlled more comprehensively.
Owner:山东宏济堂制药集团股份有限公司

Musk heartache plaster

The invention discloses a musk heartache plaster, which is prepared from the following raw materials in part by weight: 5 to 6 parts of musk, 8.5 to 9 parts of fluid extract of dahurian angelica root, 8.5 to 9 parts of fluid extract of Chinese honeylocust abnormal fruit, 6.3 to 6.8 parts of borneol, 7 to 8.5 parts of methyl salicylate, 3.1 to 3.5 parts of camphor, and 5.3 to 5.7 parts of diphenhydramine hydrochloride. A preparation method thereof comprises the following steps: 1, mixing the fluid extract of dahurian angelica root and the fluid extract of Chinese honeylocust abnormal fruit, then adding the musk, the borneol, the methyl salicylate, the camphor, and the diphenhydramine hydrochloride into the mixture for mixing; and 2, adding a substrate (made of rubber and rosin) accounting for 3.7 to 4.0 times of the total weight of the raw materials into the mixture obtained by the step 1, refining the mixture to produce paint, and carrying out grease coating, segment cutting and lining covering on the paint to obtain the musk heartache plaster. The musk heartache plaster has the advantages that: angina pectoris is cured through transdermal medicament administration by adopting a mode of cutaneous application; and the medicament is absorbed by the skin to enter the blood circulation throughout the body and reaches the effective blood concentration so as to fulfill the aim of curing or preventing the angina pectoris.
Owner:ZHENGZHOU PHARMACY WANTONG PHARMACY GROUP

External use analgesic liquid capable of activating blood, dissolving stasis and relieving swelling and pain and preparing method thereof

The invention relates to an external use health-care product, in particular to external use analgesic liquid capable of activating blood, dissolving stasis and relieving swelling and pain and a preparing method thereof. The external use analgesic liquid comprises corydalis tuber, caulis spatholobi, radix clematidis, eucommia ulmoides, radix saposhnikoviae, cassia twig, carthamus tinctorius, camphor, borneol, menthol and muscone. The preparing method comprises the step of smashing the corydalis tuber, the caulis spatholobi, the radix clematidis, the eucommia ulmoides, the radix saposhnikoviae and the cassia twig into coarse powder to be mixed with the carthamus tinctorius, the step of adding 60% ethyl alcohol for immersing for 24 hours, percolating for 24 hours, collecting the percolated liquid, stopping percolating, squeezing dregs of decoction, mixing the pressed liquid and the percolated liquid for standby application, the step of adding the smashed muscone, the camphor, the borneol and the menthol fin powder into the percolated liquid, stirring for 15 minutes, standing for 24 hours, filtering, collecting the filter liquid and adding 1000ml-solution to enable the alcohol content to be 45-55%. The external use analgesic liquid has the healthcare function of relieving pains. The external use analgesic liquid is suitable for being used by people who are suffered from pains caused by rheumatism, cold and cool, strain, injuries from falling, herniation of intervertebral disc, arthrocele pains, sciatica, cervical vertebra pains, osteoproliferation and the like.
Owner:通化斯威堂医药科技有限公司

Process for producing muscone and its intermediate

The present invention provides a process for producing a muscone represented by (1) by subjecting a citronellic acid derivative and an undecenoate to a Claisen condensation reaction to produce a keto ester compound represented by (2) decarboxylating the keto ester compound to produce 2,6-dimethyl-8-oxy-2,17-heptadecadiene, cyclizing the heptadecadiene using a metathesis catalyst to produce a 6-dehydromuscone represented by (3) and then hydrogenating the double bond. The present invention also provides the keto ester compound.
Owner:TAKASAGO INTERNATIONAL CORPORATION

Scald medicine preparation prepared from Chinese herbal medicines and preparation method thereof

The invention relates to a scald medicine preparation prepared from Chinese herbal medicines and a preparation method thereof. The scald medicine preparation is prepared from pure Chinese herbal medicines according to different proportions. The best formula comprises the following components by weight: 2100 g of sesame oil, 350 g of borneol, 450 g of garden burnet root, 320 g of gypsum rubrum, 250 g of golden cypress, 150 g of rheum officinale, 20 g of muscone, and 200 g of snakeskin. The preparation method comprises the following steps of: (a), crushing and processing various medicinal materials for the formula of the scald medicine preparation into granules with the diameter less than 2 mm; (b), putting sesame oil into a containing tank, heating the sesame oil to 60 DEG C through slow fire, preserving heat for 20 minutes, and then, putting other medicinal materials into the containing tank in turn to decoct; (c), precipitating the decocted liquid medicine; and (d), finally filling to complete preparation. The scald medicine preparation disclosed by the invention is rapid for relieving pain, diminishing inflammation, eliminating swelling, removing slough, promoting growth of tissue regeneration, converging a wound surface, and healing and regenerating epidermis and is capable of ensuring that no scar exists after healing two-degree burn and scald.
Owner:王作彦 +1

Vehicle anti-aging rubber

InactiveCN105906855AOvercome natural defectsGood oil resistancePolymer scienceBoron carbide
Vehicle anti-aging rubber comprises natural rubber, butadiene styrene rubber, butadiene rubber, epichlorohydrin rubber, silicone rubber, polyurethane rubber, ethylene propylene rubber, aromatic oil, stearic acid, coupling agents, plant polyphenol, sodium citrate, citric acid, petroleum resin, propiono phosphoric acid dioctadecyl ester, palmitamide, methyl propionate, p-phenyl dual amine, muscone, salicylic acid, argil, aromatic oil, microcrystalline cellulose, microcrystalline wax, boron carbide, magnesium stearate, polyisobutylene rubber and bismuth oxide. The anti-aging rubber can achieve excellent anti-aging effects, and aging resistance and heat resistance of the rubber are excellent.
Owner:ANHUI RUNKANG RUBBER & PLASTIC TECH CO LTD

Application of Muscone in preparing medicine for treating Alzheimer disease

The invention discloses study on application of Muscone which is called as Mus for short in preparing a medicine for treating Alzheimer disease through modern biological technologies and bioinformatic analysis. The Mus is found to have an effect of restraining A beta neurovirulence and can reduce nerve cell death, so that the Muscone can be prepared into injection preparations for treating the Alzheimer disease to be used for treating the Alzheimer disease. The injection preparation for treating the Alzheimer disease is prepared by mixing Muscone compound 2%(v / v) ethyl alcohol and 98%(v / v) normal saline according to 500mu g to 1000mu l, and in-vivo intraperitoneal injection dose of the injection preparation is 2mg / Kg / day.
Owner:NANJING DRUM TOWER HOSPITAL

Method for preparing L-muscone

The invention discloses a method for preparing L-muscone. The method comprises the following steps: (1) L-muscone in racemic muscone and a chiral hydroxybenzene compound generate L-enantiomer salt under laser irradiation; and (2) crystallization separation and hydrolysis are performed on the L-enantiomer salt to obtain a L-muscone product, wherein the step (1) is carried out in the presence of a Bronsted acid catalyst. Preferably, after hydrolysis in the step (2), separation, purification and other steps are carried out to obtain the L-muscone product. The raw material used in the method is the racemic muscone with a mature production process; batch production can be realized, diastereomer salifying resolution is carried out by adopting laser irradiation, the product selectivity is greatlyimproved, the method is green, pollution-free, and less in production of three wastes, the chiral hydroxybenzene compound is convenient to recover and reusable, the atom economy is high, the productselectivity is high, and the method is suitable for being used in the fields of biology, medical treatment, medicines, spices, cosmetics and the like.
Owner:WANHUA CHEM GRP CO LTD

Preparation method of muscone

The invention relates to a preparation method of muscone, which includes the steps of: 1) adding 1,2-diol supported on polystyrene resin, 3-methyl dienone, methylbenzene and pyridinium p-toluenesulfonate, stirring and heating the materials, cooling the materials to room temperature, and filtering the materials to produce a first ketal compound; 2) adding a first solvent and a catalyst, performingheating reflux until the reaction is finished, cooling a reaction product to room temperature and filtering the reaction product to produce a second ketal compound; 3) adding a first solvent and an acid solution, stirring the mixture until the reaction is finished, cooling a reaction product to room temperature, washing the reaction product to separate a first organic layer, and performing normalpressure recovery to the solvent in the first organic layer to collect a first ketene compound; 4) adding an alcohol solution and a metal catalyst into a reaction bottle, repeatedly replacing gas in the reaction bottle with N2 and H2, and performing a reaction at normal temperature and under normal pressure, and when the reaction is finished, performing filtration and pressure reduced rectification to obtain the muscone. The preparation method is simple in technical process and low in cost, and allows industrial large-scale production.
Owner:江西凡生实业有限公司

High-effective bioenzyme aldehyde remover and preparation method thereof

The invention discloses a high-effective bioenzyme aldehyde remover and a preparation method thereof, which includes material proportioning and preparation. Chlorophytum comosum, Chinese ivy, sansevieria and aloe have photosynthesis, thus absorbing the formaldehyde; formaldehyde lyase and benzene-series compound lyase can durably decompose the formaldehyde and benzene in a room. The aldehyde remover can absorb and decompose formaldehyde and benzene in the room; because chlorophyll is certainly limited in absorption effect and cannot absorb excessive formaldehyde, the formaldehyde lyase and benzene-series compound lyase in the aldehyde remover can completely decompose the formaldehyde and benzene from paints in the room; in addition, active carbon can absorb the odor from the formaldehyde and musk can increase fragrance in the room, and sodium percarbonate, having strong oxidizing effect, can further decompose and react the formaldehyde, so that the experiment is guaranteed to be accurate.
Owner:福建省东与恒环保科技有限公司

Fragrant ink for shorthand, handwriting, refreshing and pleasing, and preparation method thereof

PendingCN105542566AAchieve refreshmentEasy to makeInksHandwritingApothecary rose
The invention relates to a fragrant ink for shorthand, handwriting, refreshing and pleasing. The fragrant ink comprises the following raw material components in parts by weight: 100 to 500 parts of ink, 1 to 10 parts of anionic surfactant, 1 to 5 parts of essence, 1 to 5 parts of glycerinum, 1 to 6 parts of rosa gallica flower extract, 0.5 to 5 parts of palmarosa oil, 0.5 to 5 parts of lotus oil, 0.3 to 3 parts of muscone, 0.5 to 5 parts of lauric acid, 0.5 to 5 parts of lauramidopropyl betaine, and 1 to 10 parts of distilled water. A preparation method of the fragrant ink compirses the following steps of stirring and uniformly mixing the ink, the anionic surfactant and the lauramidopropyl betaine at the temperature of 50 to 70 DEG C, and cooling; uniformly mixing the essence, the glycerinum, the rosa gallica flower extract, the palmarosa oil, the lotus oil, the muscone, the lauric acid and the distilled water at normal temperature; uniformly mixing the obtained mixtures at normal temperature for use. The ink provided by the invention is fragrant, refreshing and pleasing, is convenient for shorthand, handwriting and producing high-quality documents, is rich in scholarly atmosphere, is refreshing, and is beneficial to improving the study and work efficiency.
Owner:胡益三

Method of producing macrocyclic ketone, and intermediate thereof

A process for producing muscone by methyl addition to the 1,4-conjugation of 2-cyclopentadecenone. By the process, muscone is produced in high yield not under reaction condition including an extremely low temperature and a low concentration but under practical condition. The process comprises subjecting 2-cyclopentadecenone to a 1,4-conjugation addition reaction with an organometallic methylation reagent in the presence of a copper or nickel catalyst and an enol anion scavenger to obtain a 3-methyl-1-cyclopentadecene derivative represented by General Formula (II) and then solvolyzing the enol moiety of the 3-methyl-1-cyclopentadecene derivative to obtain muscone.
Owner:TAKASAGO INTERNATIONAL CORPORATION

Medicine composition containing borneol and musk

The present invention relates to medicine composition, and especially one medicine composition containing natural plant extract or element and developed based on modern medical theory and its preparation process and application. The medicine composition contains musk and peony as main components, and is used in treating coma, cardiac and cerebral vascular diseases, senile dementia, diabetes and other diseases.
Owner:YUNNAN BIOVALLEY PHARMA CO LTD

Musk odorant with aromatic notes

The present invention relates to compounds of Formula (I), wherein the dotted line represents a carbon-carbon single or double bond and R represents a hydrogen atom or a methyl group; which are useful perfuming ingredients to impart odor notes of the musky-earthy and woody, aromatic-fresh type.
Owner:FIRMENICH SA

Method for producing 3-methyl-cyclopentadecenones, method for producing (r)- and (s)- muscone, and method for producing optically active muscone

By intramolecular condensation reaction of 2,15-hexadecanedione in a gaseous phase with a compound of a Group II element of the Periodic Table as a catalyst, 3-methyl-cyclopentadecenones is generated. Magnesium oxide, calcium oxide, or zinc oxide is desirable as the catalyst for the intramolecular condensation reaction. (R)- and (S)-muscone is generated by subjecting 3-methyl-cyclopentadecenones obtained as above to hydrogenation by using a catalyst. Palladium catalyst is desirable as the hydrogenation catalyst. Optically active muscone is generated by separating 3-methyl-cyclopentadecenones into respective components thereof by means of precision distillation and subsequently subjecting the separated 3-methyl-cyclopentadecenones to asymmetric hydrogenation by using an optically active ruthenium complex catalyst. The production methods described above enable easy and economical production of 3-methyl-cyclopentadecenones, (R)- and (S)-muscone, and optically active muscone.
Owner:DOYA MASAHARU

Trace identification method for natural Russian musk and natural forest musk

The invention relates to the fields of pharmaceutical analysis and traditional Chinese medicine identification and particularly relates to a trace identification method for natural Russian musk and natural forest musk. The method comprises a sample pretreatment step and a combined GC-MS chromatographic analysis and data treatment step. GC-MS color spectra of the natural Russian musk and the natural forest musk are contrastively analyzed, and the type of the musk can be determined by virtue of the significant difference of characteristic peaks of muscone in two types of musk and the comparisonof analysis data of the contents of muscone in two types of musk, so that the natural Russian musk and the natural forest musk can be conveniently, rapidly and accurately analyzed and judged. The operation specification and conditions of the method are specific, and the influence caused by the subjective factor of people is low, so that the accuracy and reliability of a result are remarkably improved; and furthermore, the method is simple, convenient and feasible, low in requirements on the professional level and practical experience of an operator and is vey suitable for being popularized andused in the field of pharmaceutical detection.
Owner:BEIJING FORESTRY UNIVERSITY +1

Chinese medicine composition containing red sage, notoginseng and musk or muskone and its prepn

The present invention discloses one kind of Chinese medicine composition for treating cardiac vascular diseases and its preparation process. The Chinese medicine composition is prepared with red sage, notoginseng and musk or muskone as the material medicines. The preparation process includes the following steps: 1. extracting red sage and notoginseng with water or alcohol to obtain extracted solution; 2. clarifying the extracted solution; 3. ultrafiltering the extracted solution; and 4. concentrating the filtrate to obtain extractum, and mixing the extractum with musk or muskone. The Chinese medicine composition may be prepared into different preparations, preferably dripping pill.
Owner:TIANJIN TASLY PHARMA CO LTD

External-use medicine prepared from optically active material composition and used for treating haemorrhoids and preparation technology of external-use medicine

The invention discloses an optically active raw material composition, which is prepared by using the following raw materials: L-musketone and beta heptamic acid. The invention provides an optically active raw material composition which can effectively treat hemorrhoids, has good therapeutic effect, quick effect, no recurrence, no toxic and side effects, is difficult to recur after being cured, has high biological activity utilization, and is easy for the drug to be absorbed by human skin. The external preparation prepared by the composition has short treatment period for hemorrhoids, good treatment effect, quick effect, is difficult to relapse after being cured, has no toxic and side effects, has obvious anti-inflammatory, analgesic and hemostatic functions, and can obviously eliminate granulation swelling antihemorrhoid effect. The composition and the external preparation provided by the invention can effectively treat internal hemorrhoids, external hemorrhoids and mixed hemorrhoids, and have high recovery rate and effective rate in the treatment of hemorrhoids, with the recovery rate reaching 93.9% and the effective rate reaching 100%.
Owner:中微知著药物手性技术(大连)有限公司

Muscone patch and preparation method and application thereof

The invention discloses a muscone patch and a preparation method and application thereof. The muscone patch comprises a backing layer and an anti-adhesive layer, a drug-containing adhesive layer is arranged between the backing layer and the anti-adhesive layer and comprises muscone and framework materials. The framework materials are silicone pressure-sensitive adhesive, the backing layer is polyethylene terephathalate, and the anti-adhesive layer is smooth thick paper treated with paraffin. According to the muscone patch and the preparation method and application thereof, muscone is preparedinto the patch, the defects of oral preparations and injection preparations are overcome, the first-pass effect of the liver and the gastro-intestinal inactivation can be avoided, the constant blood drug concentration is kept, the treatment effect is improved, and the toxic and side effects are reduced. By means of the patch, the use frequency of drugs can be reduced, and the patch is suitable forthe treatment of ischemic stroke in particular to the treatment in the recovery period of stroke.
Owner:山东宏济堂制药集团股份有限公司

Lavender aroma type automobile foot pad

A lavender aroma type automobile foot pad is composed of a traditional Chinese medicine blanket blank layer, an anion gluing layer and an anti-skid layer. Traditional Chinese medicine particle containing cavities and active mineral substance particle containing cavities are sequentially formed between the traditional Chinese medicine blanket blank layer and the anti-skid layer at intervals. The traditional Chinese medicine particle containing cavities and the active mineral substance particle containing cavities are a plurality of strip-shaped cavities distributed in a pedal part and side wing parts at equal intervals. Traditional Chinese medicine particles are contained in the traditional Chinese medicine particle containing cavities and comprise, by weight, 70-80 parts of rhamnus crenata, 3-5 parts of the root of bidentate achyranthes, 1-3 parts of common bluebeard herb, 15-20 parts of cyrtomium fortunei, 20-25 parts of lavender, 3-5 parts of anemone hupehensis, 15-25 parts of elm bark, 4-6 parts of agilawood, 20-25 parts of camphorwood, 3-5 parts of storax, 1-3 parts of musk, 1-3 parts of mint, 1-3 parts of astragalus membranaceus, 1-3 parts of mother chrysanthemum, 1.5-2.5 parts of sweet marjoram and 1.5-2 parts of sandalwood. The lavender aroma type automobile foot pad is high in safety performance and not only can effectively repel mosquitoes but also can release anions; meanwhile, the odor is fragrant, the character is moderate, freshness and spirit invigoration are achieved, and high application value is achieved.
Owner:魏国营

Novel Aldehydic Musks and Derivatives Thereof

A compound comprising a Schiffs base of an aldehydic musk aromachemical with a substantially nonvolatile, odorless amine, wherein the imine moiety of said Schiffs base compound is stable against oxidation to a carboxyl group or a mixture of said compounds; said Schiffs base compound being biodegradable over time to said aldehydic musk and said nonvolatile, odorless amine; as well as compositions, products, preparations or articles having improved aroma, fragrance or odor characteristics containing as active ingredient such compound or mixture of compounds; the aldehydic musks themselves, and methods for the preparation of the Schiff bases and methods of imparting fragrance characteristics to substrates.
Owner:FLEXITRAL INC
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