The invention discloses a capillary gas chromatography chiral column based on a chiral organic molecular cage material, which is prepared by the following steps: firstly, synthesizing the chiral organic molecular cage material, dissolving the chiral organic molecular cage material in a volatile organic solvent to prepare a solution, mixing the solution with a polysiloxane solution to obtain a stationary phase, and preparing the capillary gas chromatography chiral column by adopting a static column preparation method. The prepared chromatographic column shows excellent chiral resolution performance on a plurality of chiral compounds including alcohol, dihydric alcohol, halogenated hydrocarbon, epoxy compounds, esters, lactones, ketones, ethers, organic acids and the like. The chromatographic column disclosed by the invention is applied to gas chromatography resolution of the chiral compounds, has the remarkable characteristics of simple preparation method, cheap raw materials, good stability, reusability, excellent chiral resolution performance and the like, and has a very good application prospect.