117 results about "Temperature modulation" patented technology

A method for collecting optical data at two morphologically similar, substantially non-overlapping, and preferably adjacent, areas on the surface of a tissue, while the temperature in each area is being maintained or modulated according to a temperature program. The optical data obtained are inserted into a mathematical relationship, e.g., an algorithm, that can be used to predict a disease state (such as the diabetes mellitus disease state) or the concentration of an analyte for indicating a physical condition (such as blood glucose level). This invention can be used to differentiate between disease status, such as, for example, diabetic and non-diabetic. The method involves the generation of a calibration (or training) set that utilizes the relationship between optical signals emanating from the skin under different thermal stimuli and disease status, e.g., diabetic status, established clinically. This calibration set can be used to predict the disease state of other subjects. Structural changes, as well as circulatory changes, due to a disease state are determined at two morphologically similar, but substantially non-overlapping areas on the surface of human tissue, e.g., the skin of a forearm, with each area being subjected to different temperature modulation programs. In addition to determination of a disease state, this invention can also be used to determine the concentration of an analyte in the tissues. This invention also provides an apparatus for the determination of a disease state, such as diabetes, or concentration of an analyte, such as blood glucose level, by the method of this invention.

A device for providing therapy to a user including vibration and temperature modulation. The device provides mobile temperature modulation capabilities, mobile vibration capabilities, or a combination of the two. The device provides advantages to a person or animal including the ability to utilize the device in a hands-free manner. The device may also provide, under certain circumstances, pain relief or healing therapy to a person or animal.

A method of determining the analyte concentration of a test sample is described. A temperature gradient is introduced in the test sample and infrared radiation detectors measure radiation at selected analyte absorbance peak and reference wavelengths. Reference and analytical signals are detected. In the presence of the selected analyte, parameter differences between reference and analytical signals are detectable. These parameter differences, having a relationship to analyte concentration, are measured, correlated, and processed to determine analyte concentration in the test sample. Accuracy is enhanced by inducing a periodically modulated temperature gradient in the test sample. The analytical and reference signals may be measured continuously and the parameter difference integrated over the measurement period to determine analyte concentration.

Elevated temperature electrospinning apparatus comprises a pump upstream of or containing a resistance heater, means to shield applied electrostatic field from the resistance heater, and a temperature modulator for modulating temperature in the spinning region.

A thermoacoustic generating apparatus (1) is for generating acoustic waves by temperature modulation of solids, and is provided with: a thermoelement layer (12); a first electrode layer (11), laminated on one surface of the thermoelement layer; and a second electrode layer (13), laminated on the other surface of the thermoelement layer.

A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such as the DNA polymerase chain reaction. Biological samples are placed in containers each comprising a reservoir and a reaction portion, wherein the reaction portion has a small volume. The small volume reaction portion permits the rapid and accurate temperature modulation. With an optically transmissible reaction portion, DNA amplification may be monitored by fluorescence during PCR.

The nature of this invention encompasses the creation of a capillary gas chromatography (GC) column assembly and a thermal modulator used to heat or cool the column assembly in a very thermally and chromatographically efficient manner. The GC column assembly described herein consists of capillary GC column material, such as fused silica or metal capillary tubing, which is constrained to lie in a flat, ordered, spiral pattern and then encased between two thin opposing surfaces. The resulting column assembly is flat, dimensionally stable and can be very efficiently thermally modulated. The resulting column assembly also takes up very little space, has very little thermal mass, and can be easily and accurately manufactured. The column assembly can be adapted for chromatographic use by affixing it to the surface of a thermal modulator described herein by means of adhesive force or by mechanical compression, and then by attaching the free ends of the exposed column material to the input and output ports of the chromatographic device. The temperature of the thermal modulator and capillary column assembly is to be controlled by the chromatographic device or by standalone temperature controlling electronics. The thermal modulator described herein contains an element for temperature modulation of the capillary column assembly to which it is attached and a temperature sensing element for providing accurate temperature feedback to the controlling electronics. The overall result of this when coupled to a chromatographic device is maximally efficient chemical separations in a small space with minimal power consumption.

A thermal cycling method and device is disclosed. The device comprises a sample chamber whose temperature can be rapidly and accurately modulated over a range of temperatures needed to carry out a number of biological procedures, such as the DNA polymerase chain reaction. Biological samples are placed in containers each comprising a reservoir and a reaction portion, wherein the reaction portion has a small volume. The small volume reaction portion permits the rapid and accurate temperature modulation. With an optically transmissible reaction portion, DNA amplification may be monitored by fluorescence during PCR.

An electronic device and a temperature modulation method are disclosed herein. The electronic device includes a system body, a heat pipe module, a fan module, an orientation sensor, a temperature sensor and a control module. The system body includes an electronic component. The heat pipe module is connected to the electronic component. The fan module is installed in the system body. The orientation sensor can detect an orientation of the system body and output an orientation-sensing signal based on the orientation. The temperature sensor can detect a temperature of the heat pipe module and output a temperature-sensing signal based on the temperature. The control module can control rotation of the fan module according to at least one of the orientation-sensing signal and the temperature-sensing signal.

A gas turbine includes a plurality of combustion chambers; at least one fuel nozzle for each of the combustion chambers; at least one fuel line for each fuel nozzle in each of the combustion chambers; at least one heat exchanger for each fuel line configured to adjust a temperature of a fuel flow to each fuel nozzle; and a controller configured to control each of the heat exchangers to reduce temperature variations amongst the combustion chambers.

A valve assembly for mixing hot and cold water includes a generally cylindrical sleeve having hot and cold inlets and outlets and a rotatable non-reciprocal valve member positioned therein to control the mixture of hot and cold water in the outlet stream. The valve member has a hollow stem tube having hot and cold inlet and outlet ports which are rotatably engageable with the hot and cold inlets and outlets of the sleeve. The sleeve hot water outlet is generally larger than the sleeve cold water outlet. The sleeve and stem tube inlets and outlets are not limited to a particular shape and / or geometry. The fluid engagement between the sleeve hot and cold water outlets and the stem tube hot and cold water outlets provides a large mixed water temperature range.

The invention discloses a fiber-optic loop structure wound in a vertically symmetrical cross manner for a fiber-optic gyroscope. The fiber-optic loop structure comprises a fiber-optic loop skeleton which comprises a wrapping post and a middle flange, wherein the middle flange is arranged at the periphery of the wrapping post, the middle flange is provided with a fiber passing notch, horizontally run-though bellmouth orifices are arranged on the wrapping post and the middle flange and are located at the symmetrical positions of the fiber passing notch, and a fiber outlet is formed on the middle flange. A vertically symmetrical crosswise winding method for the fiber-optic gyroscope comprises the following steps: 1, setting the midpoint of an optical fiber at the position of the fiber passing notch of a fiber-optic loop; 2, winding the optical fiber; and 3, leading the optical fiber into the fiber outlet. According to the invention, a fiber-optic coil is divided into an upper part and a lower part, and each of the two parts has one side which is free of structural restriction and is not compressed in conditions of vibration and temperature variation; and through cross winding, the coils at two sides both have forward and reverse optical fibers which are the same in length, so that temperature gradients in axial and radial directions have the same temperature modulation effect on the optical fibers.

An energy recovery interior heating system has a modified mechanical or electrical drive isolation system for vehicles such as trucks. This permits a standard air conditioning compressor pump to be driven from multiple power inputs thereby providing any hybrid or non-hybrid vehicle with continuous engine-on heating and / or air conditioning, limited time engine-off heating and air conditioning and two types of engine-off air conditioning temperature modulation. Another combination of the heating and air conditioning systems would permit the continuation of heating and cooling on hybrid vehicles when they are stationary and their traction batteries are fully charged and the vehicle is operating only on the electric motors for traction or work load power. This invention also provides internal combustion engine-off heating and A / C on these types of vehicles. Another embodiment uses the drive isolation system to integrate auxiliary power unit (APU) functions as part of the traction engine of over the road trucks.

The invention relates to a bionic detection device and method for electronic nose time-space smell information. A gas sensing array and a bionic air chamber are constructed in conjunction with a temperature modulation technology and a film retardation technology, and smell information data of various substances to be identified are acquired to be identified in a classified way through a subsequent mode identification algorithm. The method comprises the following steps: changing the sensitivity and selectivity of a sensor specific to different smell components through the temperature modulation technology, forming a scanning response process specific to different components of complex smell, and acquiring rich time sequence signals of different sensors in the array; setting different breathable films / semi-breathable films in an air path, simulating biological nasal cavity and mucus functions according to the characteristic of difference of diffusion transmission rates of various gas components, and acquiring the difference through the sensors distributed at different positions, namely, spatial information reflecting air chamber spreading of the smell. By adopting the method, the time-space information of the complex gas components is acquired, and a signal foundation is laid for fine identification of complex smell.

The invention provides a method and a system for realizing continuous terahertz spectrum detection. A pair of high-stability single longitudinal mode near-infrared lasers serve as seed light sources, a laser signal is modulated by utilizing optical fibers, and continuous terahertz waves are radiated outwards under external bias potential by virtue of an optical mixer; and the terahertz waves are subjected to coherent detection at a signal receiving end by adopting a photoconductive switch and an antenna. The temperature modulation is performed on the lasers, and wide bandwidth difference frequency continuous terahertz radiation output is realized. Compared with a common terahertz time-domain impulse spectral system, the system has the advantages that the spectral resolution acquired by the technology is greatly improved, and the system has an excellent effect of promoting the development of terahertz spectroscopy and related fields.

A non-instrumented biochemical assay device, such as a device for the processing of clinical specimens for molecular diagnostic applications. In one embodiment, an assay device comprises a lid which covers a reagent tube, which is disposed on a base. The platform utilizes chemical heating and optional temperature modulation by phase change material to prepare the sample and to amplify the target nucleic acid using Loop-Mediated Isothermal Amplification. The device features a simple indicator for a positive reaction, for example turbidity or fluorescence.

A temperature modulation system for a bed, blanket, or other furniture includes a fluid for moderating temperature change, a number of conduit circuits for directing the fluid through respective zones, a control unit including a thermoelectric device for modulating temperature of the fluid, and a pump. Each of the conduit circuits selectively and independently directs fluid through its respective zone in order to produce a temperature within the zone that is independent of the temperature outside the zone. The system also includes an arrangement of one or more zones in an arrangement in which the control unit is programmed to vary the zone temperature over time according to a schedule.

The invention provides an elastic Key-Value pair data storage method based on RDMA (Remote Direct Memory Access) and HTM (High Temperature Modulation). A server-client architecture mode is designed and followed, and the method comprises the steps that at a server side, an improved G-Cuckoo Hash data management mode is given in combination with a Hashmap; the kick-out infinite loop between Hash tables caused by searching for idle positions in the data insertion process is avoided. the bottleneck problem of key value pair storage performance caused by round response required by the traditional network message transmission between the client and the server is analyzed; an Infiniband remote direct memory access RDMA technology is used, an RDMA network communication engine is designed, a data access request is received, and a data request result is sent back; a hardware transaction memory HTM technology is utilized to realize a two-section lock protocol lock operation and ensure the atomiccharacteristics of data operation; and a key value is used for self-verifying the check code of the data to guarantee data consistency. The basic operation speed of the key value on the data can be greatly improved.

The invention provides a method for realizing output of an optical microcavity coupling system by temperature modulation and a coupling structure thereof. The coupling structure is mainly characterized in that one side of the coupling system is equipped with a microheater, a lead of the microheater is connected with a temperature control device, and the whole optical microcavity, a coupler and the microheater are accommodated in a packaging body by an optical transparent packaging material. The method is characterized in that output of the optical microcavity coupling system is regulated and stabilized by adjusting and controlling the temperature of the optical microcavity coupling system. The invention solves the technical problems for developing relevant devices in the technical field and provides a feasible and simple-structure technical scheme.

The present invention is directed to temperature modulated refractive index measurement. In accordance with the invention a method for determination of the complex temperature coefficient of the refractive index of a sample is provided, wherein the determination of the complex temperature coefficient of the refractive index of the sample is based on a refractive index measurement. Furthermore, the refractive index of the sample is measured over a period of time, wherein the temperature of the sample is modulated over said period of time and the complex temperature coefficient of the refractive index is calculated on the basis of the refractive index measurement over the period of time and the temperature modulation over the period of time. Additionally, a measurement system, in particular comprising a temperature control system and a processing system to carry out the above method, is disclosed.

Aspects of the disclosure relate to fluorescence imaging, and more particularly to the use of temperature modulation in a tissue site with a modulator such as high intensity focused ultrasound to modulate the emission signal emitted by temperature-sensitive optical fluorescence reporters.

The invention provides a micromachining and manufacturing method of a gas sensor with temperature modulation. After a single crystal silicon wafer is subjected to dry oxidation by adopting an IC (Integrated Circuit) process, a silicon nitride dielectric isolation layer and an aluminum oxide dielectric isolation layer are deposited, and a platinum film is deposited by utilizing a sputtering process; patterns are copied on the other side of the single crystal silicon wafer, and a silicon cup is micromachined; a mask is subjected to photoetching and the platinum film is etched by using ion beams to form a gas sensitive unit, a gas compensation unit and a temperature sensitive unit resistor; the mask is subjected to photoetching, and an aluminum oxide layer, a silicon nitride layer, a silicon oxide layer and single crystal silicon are subjected to wet etching in sequence to form a plurality of three-leg chip units; internal leads are welded; aluminum oxide catalytic carrier slurry is coated and sintered; and a catalyst and a desensitizer are coated and subjected to thermal treatment at high temperature to form a gas sensitive chip. The method settles the problems which are present in a catalytic gas sensor owing to manual operation, realizes the integration of a plurality of sensitive units of the sensor, raises the consistency, the reliability and the detection precision of the sensor, and lowers the power consumption.

The invention provides a CMOS (Complementary Metal-Oxide Semiconductor) band-gap reference voltage generation circuit for output of the reference voltage, comprising a first CMOS, a second CMOS, a third CMOS, a first triode, a second triode, an amplifier and a fourth CMOS. The base electrode of the fourth CMOS is connected with the output end of the amplifier, the source electrode of the fourth CMOS is connected with the source electrodes of the first CMOS, the second CMOS and the third CMOS, the base electrode and the connecting electrode of the third triode are grounded. The emitting electrode of the third triode is connected with the drain electrode of the fourth CMOS. The CMOS band-gap reference voltage generation circuit, by adding a branch and a plurality of resistors, eliminates the second-order temperature modulation effect of the triode in the original circuit effectively and improves the stability of the band-gap reference voltage generation circuit.

The invention provides a temperature modulation electrochemical electrode and a heating method thereof; the electrode is composed of a power supply which can be an AC power or a DC power supply, a transformer, a measurement connector, a working electrode and a metal wire; the working electrode is processed with rapid temperature modulation through AC or DC; the temperature modulation electrochemical electrode keeps the advantages of the original thermal electrode in quickly and easily controlling the electrode temperature, improving the mass transfer rate of the system, increasing the detection sensitivity, lowering the detection limit and removing the pollutants on the electrode surface. Moreover, compared with the symmetrical structural design of the original thermal electrode, the invention simplifies the structure and can effectively eliminate the interference on electrochemical detection caused by the heating of current, so that the heating and the detection can be carried out atthe same time to achieve a better application effect; besides, the invention provides a plurality of practical and new thermal electrode materials, and has a wider application range.