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39 results about "Optical fluorescence" patented technology

Optical fluorescence occurs when a molecule absorbs light at wavelengths within its absorption band, and then nearly instantaneously emits light at longer wavelengths within its emission band.

Ingestible device platform for the colon

An ingestible pill platform for colon imaging is provided, designed to recognize its entry to the colon and expand in the colon, for improved imaging of the colon walls. On approaching the external anal sphincter muscle, the ingestible pill may contract or deform, for elimination. Colon recognition may be based on a structural image, based on the differences in diameters between the small intestine and the colon, and particularly, based on the semilunar fold structure, which is unique to the colon. Additionally or alternatively, colon recognition may be based on a functional image, based on the generally inflammatory state of the vermiform appendix. Additionally or alternatively, pH, flora, enzymes and (or) chemical analyses may be used to recognize the colon. The imaging of the colon walls may be functional, by nuclear-radiation imaging of radionuclide-labeled antibodies, or by optical-fluorescence-spectroscopy imaging of fluorescence-labeled antibodies. Additionally or alternatively, it may be structural, for example, by visual, ultrasound or MRI means. Due to the proximity to the colon walls, the imaging in accordance with the present invention is advantageous to colonoscopy or virtual colonoscopy, as it is designed to distinguish malignant from benign tumors and detect tumors even at their incipient stage, and overcome blood-pool background radioactivity.
Owner:SPECTRUM DYNAMICS MEDICAL LTD

Method and apparatus for medical imaging using near-infrared optical tomography and flourescence tomography combined with ultrasound

Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.
Owner:UNIV OF CONNECTICUT

Light emitting device, and illumination light source, display unit and electronic apparatus including the light emitting device

InactiveUS20110211336A1No lot-to-lot variationColor tone is easilySolid-state devicesIlluminated signsOptical fluorescencePeak value
A light emitting device includes: a first semiconductor light emitting element having a solid-state blue light emitting element that emits blue light with a light emission peak in a wavelength range from 420 nm to less than 480 nm, and a first red phosphor layer that covers the solid-state blue light emitting element and includes a first red phosphor that emits red light with a light emission peak in a wavelength range from 600 nm to less than 680 nm; and a second semiconductor light emitting element having a solid-state green light emitting element that emits green light with a light emission peak in a wavelength range from 500 nm to less than 550 nm, and a second red phosphor layer that covers the solid-state green light emitting element and includes a second red phosphor that emits red light with a light emission peak in a wavelength range from 600 nm to less than 680 nm.
Owner:PANASONIC CORP

Endoscope

The invention provides an endoscope which comprises a connecting optical fiber, a self-focusing lens, a slant reflection mirror and a motor. The connecting optical fiber is connected with the tail portion of the self-focusing lens, the slant reflection mirror is opposite to the self-focusing lens, the rear end of the slant reflection mirror is fixed with one end of a rotary shaft, the other end of the rotary shaft is fixed with one end of a column magnet, a supporting sleeve is arranged outside of the rotary shaft, the column magnet, the rotary shaft, the slant reflection mirror and the self-focusing lens are coaxial, and a transparent sleeve is arranged outside the column magnet, the rotary shaft, the slant reflection mirror and the self-focusing lens, and the supporting sleeve and the self-focusing lens are both fixed with the transparent sleeve. A pair of plate magnets with opposite S poles and N poles is arranged on the power output end of the motor in the circumferential direction, a power output shaft of the motor is coaxial with the rotary shaft, and the plate magnets are adjacent to the column magnet. The endoscope is high in flexibility, the outer diameter of the transparent sleeve can be less than 1mm and even can reach micron dimension, and a use range is wide. The endoscope is applicable to an OCT system and imaging systems of optical scanning imaging, scanning fluorence imaging, B ultrasonic imaging and the like.
Owner:SHANGHAI JIAO TONG UNIV

Method and Apparatus for Terahertz or Microwave Imaging

An apparatus and method for imaging using microwave or terahertz radiation are described. The apparatus (10) comprises: a cell (12) comprising a vapour of atoms; one or more laser beams (14) propagating through said cell (12), said one or more laser beams (14) defining a sensing region (15) in said cell (12); an imaging beam (16) for illuminating an object receiving area for receiving an object (18) to be imaged, said imaging beam (16) comprising microwave or terahertz radiation; an imaging system (20, 22) for focussing the imaging beam (16) to form, in use, an image of said object (18) at said sensing region (15) in said cell (12); wherein respective frequencies of said one or more laser beams (14) and said imaging beam (16) are such that at least some of said atoms, when subjected to radiation of both said one or more laser beams (14) and said imaging beam (16), are excited to a final excited state which decays to a lower energy state by emission of optical fluorescence (24).
Owner:UNIVERSITY OF DURHAM

Fluorescent emulsion

InactiveCN102170913ASuppress or even block spurious signalsMaterial analysis using wave/particle radiationEmulsion deliveryFluorescenceOil in water
The invention relates to a fluorescent emulsion, to its uses and to labelling reagents comprising it. The fluorescent emulsion of the invention is of the oil-in-water type, comprising at least one aqueous continuous phase in which droplets of at least one oil phase are dispersed, said oil phase droplets being stabilized by a surfactant layer, characterized in that it comprises at least one pair of labels, differing from one another, formed from a donor fluorescent label that absorbs at a wavelength lambda1 and emits at a wavelength lambda2 different from lambda1, and an acceptor label that absorbs at the emission wavelength lambda2 of the donor fluorescent label; in that the donor fluorescent label and the acceptor label are kept close together by the encapsulation of one of them in the oil phase droplets and either by linking the other of them to the oil phase droplet / aqueous phase interface, or by the encapsulation of the other of them in the oil phase droplets; and in that it comprises molecules of at least one amphiphilic surfactant and at least one solubilizing lipid. The fluorescent emulsion of the invention is applicable in the field of optical fluorescence imaging, in particular optical fluorescence biomedical imaging.
Owner:法国原子能与替代能源委员会

Device for improving performance in STED and RESOLFT microscopy using a single phase mask

The present invention refers to a method for high spatial resolution imaging comprising a phase plate or a spatial light modulator (SLM) device for STimulated Emission Depletion (STED) microscopy and Reversible Saturable OpticaL Fluorescence Transitions (RESOLFT) microscopy, where a bivortex pattern is imprinted on the said phase plate or SLM to generate a beam. The bivortex pattern allows some freedom in shaping the STED beam to improve the microscope's axial performance and optical sectioning capacity.The present invention further refers to a method for STED and RESOLFT microscopy comprising the step of modulating the optical phase of a laser using a phase plate or a spatial light modulator device with a phase mask comprising a bivortex with a tunable radius.The disclosed phase masks and methods of STED and RESOLFT microscopy may advantageously be applied to provide a hybrid 2D / 3D STED regime but one with a significant reduction in the degrees of freedom for alignment relative to what is found in incoherent beam superpositions, thus providing an improvement in beam quality, namely a minimized central intensity and lower sensitivity to aberrations, resulting in an increased signal level and axial performance.
Owner:INST DE BIOLOGIA MOLECULAR E CELULAR IBMC
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