The invention discloses a mouth rehabilitation material and a preparation method thereof. The mouth rehabilitation material is prepared from, by mass, 0.6%-2% of cerium oxide, 0.8-3% of yttrium oxide, 1%-4% of borax, 2%-4% of sodium stannate, 3%-5% of silicon dioxide, 15%-24% of aluminum oxide and the balance zirconium oxide. The mouth rehabilitation material is directly subjected to injection molding to obtain a ceramic tooth part, the tensile strength is high, the linear expansion coefficient is small, the Rockwell hardness is high, the yield strength is high, the advantages of being high in hardness, strength and toughness and the like are achieved, that is, good mechanical performance and processability are achieved, and meanwhile more excellent corrosion resistance is achieved. In addition, the ceramic tooth part obtained through direct injection molding of the mouth rehabilitation material and the tooth body of the human body are equivalent in refractive index, the ceramic tooth part is closer to the teeth of the human body, and clinical use is more attractive.