583 results about "Bone grafting" patented technology

The invention is directed to a composite bone graft for implantation in a patient, and methods of making and using the composite bone graft, along with methods for treating patients by implanting the composite bone graft at a site in a patient. The composite bone graft includes two or more connected, discrete, bone portions, and includes one or more biocompatible connectors which hold together the discrete bone portions to form the composite bone graft. The composite bone graft may include one or more textured bone surfaces. The textured surface preferably includes a plurality of closely spaced protrusions, preferably closely spaced continuous protrusions. The composite bone graft is useful for repairing bone defects caused by congenital anomaly, disease, or trauma, in a patient, for example, for restoring vertical support of the anterior and / or posterior column. Implantation of the composite bone graft results in improved graft stability and osteoinductivity, without a decrease in mechanical strength. The composite bone graft does not shift, extrude or rotate, after implantation. The present composite bone graft can be appropriately sized for any application and can be used to replace traditional non-bone prosthetic implants.

An expandable intervertebral prosthesis includes a bone graft implant member dimensioned for insertion within an intervertebral space defined between adjacent vertebrae, thereafter adapted to vertically elevate and expand a plurality of barbs into the surrounding bone. The expandable intervertebral prosthesis has a tubular outer body portion having an axial bore with an enlarged proximal end and an exterior surface dimensioned to fit snugly within the space, and a barbed expansion cylinder slidably or rotatably mounted within the axial bore. The tubular outer body portion of the expandable intervertebral prosthesis has a plurality of longitudinal slots or holes in the wall thereof to allow the expansion and retraction of the expansion cylinder's barbs into or out of the surrounding bone. The barbs on the expansion cylinder may be elastically deformed from a normal, retracted configuration to a locking, splayed configuration wherein the outer ends of the barbs extend outwardly through the slots and exterior surface of tubular outer body to penetrate the surrounding bone as the expansion cylinder is moved. The expansion cylinder and, in one embodiment, the exterior surface of the tubular outer body portion, have a plurality of barbs disposed in circumferentially spaced relation about the body and positioned in various angles and positions respect to the axial bore. In another embodiment, the intervertebral prosthesis includes an elevating cylinder rotatably mounted within a frangible tubular outer body portion. The elevating cylinder has one or more detent positions that expand and vertically elevate the frangible tubular outer body portion of the intervertebral prosthesis body upon rotation thereof.

Disclosed is a delivery system for an intervertebral spacer and a bone grafting material in the form of a unitary device which comprises a spacer disengagingly attached to a hollow handle. The handle comprises a chamber and bone grafting material-advancing means within the chamber for introducing the bone grafting material from the chamber into and around the spacer and the intervertebral spaces. The handle is disengageable from the spacer after serving its purpose of facilitating placement of the spacer and the discharge of the bone grafting material into the spacer and the intervertebral space.The intervertebral spacer implant portion is attached to the handle portion at the exit port of the chamber, the point of attachment constituting the entry port of the intervertebral spacer implant portion.The spacer has voids therein capable of receiving the bone grafting material from the chamber, and the chamber, the spacer implant portion voids, and the intervertebral spaces are in flow communication with each other whereby bone graft material expressed from the chamber is capable of entering the intervertebral spacer implant voids and the intervertebral spaces.

A system and method to facilitate bone grafting, the system including a rasp configured to prepare the grafting surfaces of a recipient, a sizer configured to determine the dimensions of a graft for abutment with the grafting surfaces, a cutting guide configured to receive bone stock and to facilitate producing the graft in proportion to the sizer, a measuring pan configured to determine the amount of grafting substance required to fill the void in the graft, and a holding device configured to stabilize the graft as the grafting substance is placed in the graft.

A disposable, bone graft harvester having a clear, graduated plastic tube tipped with a bone cutting head at one end and a handle or other torque supplying connection at the other end.

A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less.

The invention relates to the technical field of medical machinery, in particular to a first tread wedge joint plate. The first tread wedge joint plate comprises a plurality of fixing holes which are used for fixing the first tread wedge joint plate on a first metatarsal bone and an internal side wedge bone; a sliding hole which enables pressing between bones to be convenient during fusion of the first tread wedge joint is formed in the first tread wedge joint plate. According to the first tread wedge joint plate, tender moving of the first tread wedge joint surface is allowed when the bridge first tread wedge joint plate is fixed, namely, the first tread wedge joint surface gristle is kept and the joint is limited from moving; when the first tread wedge joint fuses the first tread wedge joint plate to be fixed, bone grafting after joint surface gristle is removed, pressing of the first tread wedge joint surface is achieved through a sliding hole at a far end of the first tread wedge joint plate, and accordingly the fusion rate is improved; the first tread wedge joint plate is in an anatomy type design, anatomical reduction is convenient, pre-bending of the first tread wedge joint plate during operation is not required, and the intensity of the first tread wedge joint plate is avoided from being influenced by bending during the operation.

A sac composed of woven bio-absorbable suture with an opening (2) for placement of bone graft or bone graft substitutes (5). The device is contoured and sized for positioning in various anatomic areas (FIGS. 3, 4, and 7) and may be coupled to an implantable electronic fusion stimulator device (6 and 7).

A process with special instruments to Arthroscopically reduce certain joint fractures in humans and animals. The instruments are shaped and sized so as to afford remote manipulation of bone fragments, while viewing the procedure with an arthroscope and a fluoroscope in a C Arm. The process utilizes a lateral approach. This process with the instruments allows a skilled surgeon to affect an anatomically correct joint surface and then bone graft any bone deficit, all through small incisions local to the joint.

The present invention is one kind of new inorganic bone grafting material and belongs to the field of medical material. The inorganic bone grafting material consists of beta-tricalcium phosphate grain in 20-80 wt% and alpha-calcium sulfate semihydrate powder in 20-80 wt%, and the alpha-calcium sulfate semihydrate powder form layered structure in the surface and / or pores of beta-tricalcium phosphate grain. Both beta-tricalcium phosphate and alpha-calcium sulfate semihydrate have excellent biocompatibility and excellent in vivo degrading performance, and the composite artificial bone grain may be used in repairing bone defect of different shapes. The composite artificial bone grain has wide material source, convenient use, excellent performance, simple preparation process, low cost and other advantages.

A titanium-mesh umbrella for bone grafting used to combine with conventional implant and to hold bone graft in proper position during dental implant placement procedure, comprises: a titanium metal shank with one end as implant end and the other end having a pin hole at its center to form a mounting portion; a titanium-mesh with its surface having a plurality of screen meshes, wherein said titanium-mesh encircles an area with a diameter in horizontal direction and forms a projecting umbrella surface with a curvature in perpendicular direction, a rough surface being formed on said projecting umbrella surface, said umbrella type titanium-mesh being able to position quickly on the mounting portion of said metal shank to form an umbrella structure. Thus, the titanium metal umbrella can be positioned quickly during dental implant placement procedure, so that the guide tissue membrane can be securely attached, a space for bone graft growing can be maintained, and the operation duration can be shortened.

Osteoconductive bone graft materials are provided. These compositions contain injectable cements and demineralized bone matrix fibers. The combination of these materials enables the filling of a bone void while balancing strength and resorption.

The invention provides a mineralized collagen artificial periosteum. The artificial periosteum is prepared from mineralized collagen in which nano calcium phosphonium salt and collagen fibers are arranged in order, has substances and micro and macro structures, which are the same as a natural periosteum, also has a favorable mechanical property and biodegradation properties, and can be used for replacing and restoring the periosteum. The artificial periosteum can limit other bone grafting materials in the bone fracture parts in the restoring process to prevent the bone grafting materials from coming out and muscles, fat and other tissues from being extruded into the bone fracture parts, so that the restoring effect cannot be influenced. The pore structure of the artificial periosteum facilitates revascularization and conveying of nutrient substances, thereby benefiting restoring of bone fractures. Since the mineralized collagen artificial periosteum consists of nano calcium phosphonium salt and the collagen fibers, the artificial periosteum can be gradually degraded along with regeneration of bone tissues and the periosteums in the body. The invention also provides a preparation method of the artificial periosteum.

An internal sinus manipulation procedure for augmenting bone of a dental patient between the floor of the patient's sinus and a raised portion of the patient's sinus membrane comprising exposing a portion of the patient's sinus membrane immediately adjacent the floor of the patient's sinus followed by (i) a simultaneous and controlled lifting and lateral separation of the exposed portion of the sinus membrane from the sinus floor to form an open pocket between the sinus membrane and the sinus floor, (ii) introduction of a bone grafting material into the pocket and (iii) a compacting of the bone grafting material.

An apparatus for depositing bone graft material into a mammalian body comprises a barrel member having an inner surface with internal threads. The barrel includes an exit port through which bone graft material placed into the barrel exits the barrel. A plunger member is disposed coaxially within the barrel member for pushing the bone graft material toward the exit port in the barrel. A mechanism is provided for advancing the plunger member within the barrel member. The plunger member can be rotatable and include external threads that are complimentary to and engaged with the internal threads in the barrel member to assist in moving the bone graft material toward the exit port in the barrel.

A bone grafting material, a method of producing the same, and an implant. The bone grafting material comprises a porous carrier of ceramic or glass ceramic or glass material and at least one pyrrolidone arranged in the carrier.

The invention relates to a method for designing and manufacturing a repair-orientated planting bone augmentation guide plate. The method comprises the following steps: shooting CT of a patient to obtain a planting three-dimensional space; carrying out intraoral three-dimensional scanning or scanning a gypsum model to obtain patient data; fusing the two parts of data; designing missing teeth and a tooth long shaft; locating an implant by using the tooth long shaft; adjusting the position and posture of the implant; extracting mesiodistal ortho-tooth half-crown data in the tooth missing region, and increasing the thickness uniformly; measuring the straight line-segment distance between the occlusal surface and the tail end of the implant body; generating a three-dimensional digital model of the planting guide plate; and designing the outer surface of the bone augmentation area after bone graft, increasing the thickness, and reserving a bone grafting material filling hole, thus completing designing and processing. According to the method provided by the invention, the mesiodistal position, the buccolingual position, the torque angle and the shaft inclination degree for oral implantation of the tooth implant can be accurately guided, the accurate bone augmentation operation is realized, the tooth planting risk is reduced, the implant amount and surface form of the allogenic bone augmentation material can be conveniently and accurately controlled, and thus the success rate of the tooth planting operation can be improved.

A composite chitosan / nano-hydroxyapatite microsphere-based material used for bone-grafting and delivery of therapeutic agents. The composite material may be produced using co-precipitation methods. The composite material may be used to form scaffolds with significantly greater surface area and surface roughness than scaffolds composed of only chitosan. Composite scaffolds exhibit less swelling and greater toughness and flexibility than scaffolds fabricated by other techniques. Composite scaffolds also exhibit greater osteoblast proliferation. Composite scaffolds also may contain therapeutic agents or medicaments, and may be lyophilized.

A borate bioactive glass is described, and may be used in the form of particles in an acidic mixture to form a borate bioactive glass paste. The borate bioactive glass paste may be used for the restoration of dentin and enamel on a tooth surface by the precipitation of calcium phosphate. The borate bioactive glass may also be used as a bone grafting material.

Computer implemented methods of producing a bone graft are provided. These methods include obtaining a 3-D image of an intended bone graft site; generating a 3-D digital model of the bone graft basedon the 3-D image of the intended bone graft site, the 3-D digital model of the bone graft being configured to fit within a 3-D digital model of the intended bone graft site; storing the 3-D digital model on a database coupled to a processor, the processor having instructions for retrieving the stored 3-D digital model of the bone graft and for combining a carrier material with, in or on a bone material based on the stored 3-D digital model and for instructing a 3-D printer to produce the bone graft. A layered 3-D printed bone graft prepared by the computer implemented method is also provided.

A method of maxillary sinus bone grafting for placement of an implant in which upon placement of the implant, a vertical hole is formed and enlarged with ease in a maxillary sinus floor, a maxillary membrane is easily lifted in an always-stable state using a piezotome and gel type bone graft material while preventing the membrane from becoming damaged, and even the bone graft material of coarse bone meal is uniformly diffused and infused, thereby ensuring that the implant is placed in a fast, safe manner while allowing a patient to keep relaxed and alleviating the pain the patient feels, resulting in shortening a curing time and maximizing effects of the placement of the implant.

A system for generating a model of a patient specific cut guide instrument for harvesting a graft comprises a model of a graft defined by an implant interface surface, a bone interface surface, and a spatial geometry therebetween, the model being specific to a patient. A patient-specific instrument generator outputs the model of the patient specific cut guide instrument, the patient-specific instrument generator including a position determination module for orienting and positioning at least a first guide axis, and for positioning an abutment on a model of a donor bone as a function of the spatial geometry, and an instrument body generator module for generating a model of the patient specific cut guide instrument comprising a body supporting a cut guide to perform a depth cut in the donor bone positioned and oriented as a function of a contact of the body with the abutment on the donor bone, and of the model of the graft, a first guide channel for alignment with the first guide axis, and at least one anchor guide for securing the patient specific instrument cut guide on the donor bone as abutted with the abutment and aligned with the first guide axis, whereby the patient specific cut guide instrument is used for harvesting the graft for subsequent implanting without alterations to the spatial geometry of the graft.

The invention relates to a bone grafting device for tubular bone defect healing, and belongs to the technical field of orthopedic medical devices. The bone grafting device is used for grafting tubular bones to promote the healing of the tubular bones, and comprises an outer sleeve, an inner sleeve and a connecting rod, wherein the inner diameter of the outer sleeve is matched with the outer diameter of the two ends of a tubular bone defect part required for bone grafting, and the inner sleeve is positioned in the outer sleeve; the connecting rod is inserted in the inner sleeve, and the diameter of the connecting rod is matched with the inner diameter of the inner sleeve; and the length of the connecting rod is greater than that of the inner sleeve, and the inner sleeve and the outer sleeve are made of biodegradable magnesium alloy. In the bone grafting device, the connecting rod in the inner sleeve can firmly connect the two ends of a defective tubular bone, a high-quality autologous cancellous bone is filled between the inner sleeve and the outer sleeve to simultaneously play roles of bone grafting and reinforced fixing, and the biodegradable magnesium alloy has a function of inducing bone formation, thereby the fracture healing is promoted. The bone grafting device has the advantages of firm bone grafting, high intensity, early ambulation for patients, and good clinical effect.

The invention relates to an auxiliary bone grafting bracket for a large bone defect, which has the structure that an outer mesh pipe is sleeved outside an inner mesh pipe; a plurality of connecting rods are connected between the outer wall of the inner mesh pipe and the inner wall of the outer mesh pipe; the pipe walls of the inner mesh pipe and the outer mesh pipe are distributed with meshes; and both ports of the inner mesh pipe are respectively positioned at the inner sides of both port planes of the outer mesh pipe. The bone compensating bracket is suitable for the bone defect treatment of a wound without inflammation. By grafting the bone compensating bracket into the bone defect part of a patient, the curing effect of a bone defect disease can be effectively improved, and a feasible, practical and efficient new scheme is provided for the treatment of the large bone defect.

The invention discloses a designing and making method of a customized 3D printing porous titanium alloy segmental prosthesis for reconstruction of large segmental bone defect. Through preoperative thin-slice CT, a lesion bone area is scanned, obtained data is imported into a computer, and a three-dimensional digital model is reconstructed through computer aided design. Then, in combination with such imageological examination as MRI (magnetic resonance imaging) and the like, an osteotomy range of the lesion part is determined. The individual porous titanium alloy segmental prosthesis is designed in accordance with the specific osteotomy range and a reconstruction method. Prosthesis data is imported into metal 3D printing equipment so as to print the prosthesis. During an operation, lesion bone can be excised by virtue of such precision operation assisted technologies as navigation, a guide plate and the like. Then, a proper autogenous fibula (or biological ceramic artificial bone and allogeneic bone) is selected for conducting composite bone grafting. Finally, a complex is implanted into a bone defect area and is stably fixed. The method can complete precision making by virtue of a 3D printing technology and can achieve precision excision by virtue of the navigation and guide plate technologies, so that precision reconstruction of the large segmental bone defect is finally achieved.

The invention discloses a dislocation prevention type non-fusion artificial cervical vertebra and intervertebral disc system comprising a vertebra body component and two end plate components, wherein the end plate components are connected to the upper end and the lower end of the vertebra body component respectively through a dome joint structure and L-type dislocation prevention structures on the front side and the rear side. End plate fixing screws are arranged on the two end plate components respectively. After corpectomy, the system can play a role in supporting at once, the motion function of the normal cervical vertebra is replaced through own interbody connecting parts, stress of the cervical vertebra can be dispersed in the motion process, internal stress of adjacent segment intervertebral discs and zygapophyseal joints can be reduced, and degeneration, which is caused by fusion, of the adjacent segments can be effectively prevented. In addition, stable bony fusion can be achieved through bone grafting and a hydroxyapatite coating on the surface of the system. The operation difficulty is small, trauma is small, and the system is convenient to popularize. Due to the fact that the dislocation prevention positions of the system are arranged, long-period stability can be achieved after the operation.

The invention relates to a lifting interbody fusion device and an operation device for driving the same. The lifting interbody fusion device comprises a screw, a middle limiting frame, an upper lifting block and a lower lifting block. The upper lifting block is arranged on the outer side of the upper portion of the middle limiting frame in a sleeving mode, the lower lifting block is arranged on the outer side of the lower portion of the middle limiting frame in a sleeving mode, at least two first inclined grooves and at least two second inclined grooves are formed in each of the two side walls of the middle limiting frame, the inclination directions of the first inclined grooves and the second inclined grooves are opposite, first bolts in sliding fit with the first inclined grooves are arranged on the slide walls of the upper lifting block, second bolts in sliding fit with the second inclined grooves are arranged on the slide walls of the lower lifting block, and the screw is connected with the middle limiting frame through threads and limited on the upper lifting block or the lower lifting block. The interbody fusion device is adjustable in height and stable in use; besides, the inner space of the interbody fusion device is large, the bone grafting space in an operation is large, the bone grafting quantity is large, and the healing success rate is high.