54 results about "Tissue membrane" patented technology

An organism tissue suturing apparatus for suturing a penetrated hole formed subcutaneously in a tissue membrane of an organism includes a body part having a predetermined length. The body part includes a rotary portion, disposed at a front end thereof, that can be inserted into the tissue of the organism from the hole, a needle member accommodated in a portion, inside the body part, rearward from the rotary position, and a pressing mechanism for advancing the needle member from a side surface of the body part and pressing the needle member into the rotary portion. The rotary portion has a needle member receiving portion for receiving essentially a front end of the needle member pressed into the rotary portion by the pressing mechanism, with the rotary portion disposed in the tissue of the organism. The needle member has a suturing thread of a duct for the suturing thread.

The invention provides for a transdermal drug delivery device for forming a drug delivery patch system comprising:a) an actuator comprising:i) an outer body defining a top of the actuator, the outer body containing a cavity;ii) a controller board comprising driving electronics and a battery, the controller board being positioned within the cavity; andiii) an interface connection port for receiving a porator array, the interface connection port containing an anode and a cathode;b) the porator array comprising:i) a top surface, with a removable adhesive attached to the top surface, the top surface containing two concentric electrical contact rings for contacting the interface connection port at the anode and the cathode upon removal of the adhesive layer;ii) a bottom surface comprising a tissue interface membrane, the tissue interface membrane further comprising a substrate with at least one porator contained on or within the substrate, the bottom surface further comprising an adhesive layer for attaching the porator array to a tissue membrane; andiii) an extension tab laterally and removably attached to the bottom surface, the extension tab including an adhesive applied on the bottom thereof, thereby allowing the extension tab to remain on the tissue membrane upon removal of the porator array; andiv) a release liner removably attached to the bottom surface; andc) a reservoir patch attached to the extension tab, the reservoir patch being applied to the microporated area of the tissue membrane after poration.The invention also provides for methods of making and methods of using the same.

A biological nerve guide for implantation into a human body is made by providing a natural animal tissue membrane, crosslinking and fixing the membrane, minimizing the antigens from the membrane, tanning the membrane, coupling an active layer to an inner surface of the membrane, cutting the membrane into a desired shape and size, positioning the cut membrane onto a rod-shaped mold so that the cut membrane assumes a cylindrical configuration, and attaching a spiral support to the outer surface of the cut membrane.

A living body tissue closing device 1 includes an elongated body element 2, a clip (living body tissue closure) 4 for closing a wound hole which penetrates a living body tissue membrane, and a thread 8. The body element 2 includes a sheath 5, and elongated feeding and deformation means 3. The elongated feeding and deformation means 3 includes a covered tube 6, a pusher tube 7, a thread anchoring cap 9, a guide wire 11, and a stopper 12. The clip 4 includes a seal portion 41 for covering the wound hole and a peripheral portion of the wound hole from one side of the living body tissue membrane, a deformation portion 42 deformable between a first form in which the deformation portion 42 can pass through the wound hole and a second form in which the deformation portion 42 can cooperate with the seal portion 41 to sandwich the living body tissue membrane therebetween from the other side, and a fastener portion 43 for retaining the deformation portion 42 in the second form.

A device is disclosed for detecting a voltage potential from a tissue membrane. The device includes an input circuit, an output circuit and a digital signal processor. The input circuit receives a membrane voltage potential from an electrode. The output circuit receives an output command signal and provides a current output signal to the electrode. The digital signal processor is coupled to the input circuit and the output circuit. The digital signal processor provides the output command signal, and waits a delay period prior to receiving the membrane voltage signal from the input circuit.