70 results about "Heart protection" patented technology

A pacing system delivers cardiac protection pacing to protect the heart from injuries associated with ischemic events. The pacing system detects an ischemic event and, in response, initiates one or more cardiac protection pacing sequences each including alternative pacing and non-pacing periods. In one embodiment, the pacing system initiates a cardiac protection pacing sequence in response to the detection of the onset of an ischemic event, such that a pacing concurrent conditioning therapy is applied during the detected ischemic event.

Cardiac protection pacing is applied to prevent or reduce cardiac injury and / or occurrences of arrhythmia associated with an ischemic event including the occlusion of a blood vessel during a revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through one or more pacing electrodes incorporated onto a percutaneous transluminal vascular intervention (PTVI) device used in the revascularization procedure. The pacemaker generates the pacing pulses according to a predetermined cardiac protection pacing sequence before, during, and / or after the ischemic event.

A pacing system includes a pacemaker and a pacing protocol module externally attached to the pacemaker. The pacing protocol module stores the pacing protocol. The pacemaker controls delivery of pacing pulses by automatically executing the pacing protocol. In one embodiment, the pacing protocol is a cardioprotective pacing protocol for preventing and / or reducing cardiac injury associated with myocardial infarction (MI) and revascularization procedure. The pacing pulses are generated from the pacemaker and delivered through one or more pacing electrodes incorporated onto one or more percutaneous transluminal vascular intervention (PTVI) devices during the revascularization procedure.

The invention relates to toothpaste with plant ingredients, in particular to healthcare toothpaste for reducing pressure and protecting the heart. The healthcare toothpaste for reducing pressure and protecting the heart comprises a matrix for the toothpaste, fructus gardenia extract, pagoda tree flower extract, chrysanthemum extract, a celery extracting solution and radix polygonati officinalis extract. The toothpaste has the advantages that active ingredients in fructus gardenia extract and chrysanthemum extract have a synergistic effect on the aspects of clearing heat and fire, a pressure reducing function is enhanced, the oral cavity can be protected, the liver can be protected, and lipid can be reduced; active ingredients in pagoda tree flower extract can expand the blood vessels, increase the blood flow volume of the sublingual blood vessels, and the active ingredients of celery extract and radix polygonati officinalis extract can be absorbed into blood conveniently. The five kinds of extract are combined for use, the synergistic effect is achieved, and the effects of heart protection and healthcare are better. The materials are mainly used for preparing the healthcare toothpaste for reducing pressure and protecting the heart.

A heterocyclic compound with ethyl guanidine connection and its medicinal use are disclosed. The compound contains optical isomer or diastereomeric mixture, their medicinal salt, group and potassium channel developer and calcium spiking agent. It can be used to treat and prevent cardiac lassitude and cardiovascular diseases.

The invention discloses recovery-type traditional Chinese medicine edible oil which comprises 40-60% of edible vegetable oil, 9-12.5% of sea buckthorn oil, 8-11.5% of eucommia oil, 5-14% of taraxacum oil, 5-12% of honeysuckle oil, 6-8% of lithospermum erythrorhizon extract and 1-2% of rosmarinus officinalis extract and tert-butylhydroquinone. The invention further discloses a preparation method of the edible oil. The preparation method comprises the steps of (1) cleaning a packaging bottle, putting the packaging bottle into a disinfection cabinet, and performing disinfection for standby, (2) weighing the substances according to a weight ratio, performing mixing, and performing stirring and heating for 1-3h at 170 DEG C, (3) performing encapsulation into the packaging bottle, and (4) plugging and sealing the packaging bottle. The edible oil effectively removes in-vivo viruses, kills malignant bacteria, eliminates inflammation and promotes blood circulation, so that the edible oil can achieve cancer treatment, immunomodulation, blood pressure reduction, blood glucose reduction, liver protection, anti-ageing, beautifying, endocrine regulation, anti-inflammation, anti-virus, analgesia, heart protection and anti-coagulation effects, and has a significant effect on recovery hepatitis B, hepatocirrhosis, a heart disease, diabetes, hypertension, an acquired immune deficiency syndrome, a cancer and the like.

The invention belongs to the field of medical X-ray protection, and particularly relates to CT (Computed Tomography) protective clothing. The CT protective clothing comprises a body, wherein the body comprises a coat and a pair of trousers; the body also comprises a front coat piece, a back coat piece, a dismountable one-piece cap, dismountable one-piece gloves and dismountable one-piece foot sleeves; the front coat piece comprises an elastic tightening belt, a heart protection sheet and inspection windows; inspection windows and a back tightening buckle are arranged on the back coat piece; and a fabric of the body is a composite fabric formed by pressing composite materials. The CT protective clothing has the advantages that the wearing is convenient; the fully sealed protection can be realized; the X-ray blocking rate reaches 99 percent; meanwhile, the sterilization and anti-microbial effects are achieved; and the pathogenic bacterium spreading phenomenon due to the wearing by many people is effectively avoided.

Disclosed is a system for the detection of cardiac events that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using different algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and / or an external alarm system (external alarm means) which are activated after the ST segment of the electrogram exceeds a preset threshold.

The invention relates to a selenium-rich radix astragali heart protection oral liquid which is characterized by comprising the following materials by weight: selenium-rich radix astragali 10 to 30 g, selenium-rich sealwort 15 to 20 g, adenophora elata 10 to 20 g, achyranthes bidentata 10 to 20 g, ophiopogon japonicus 10 g, Chinese magnoliavine fruit 10 g, selenium-rich angelica sinensis 10 g, selenium-rich gynostemma 15 to 20 g, and honey of an appropriate amount. The selenium-rich radix astragali heart protection oral liquid enhances the Qi tonifying and heart protecting functions of radix astragali than other heart protection oral liquids, and pays more attention to internal relation between the cardiac function and other visceral organs; sealwort is adopted for tonifying Qi, nourishing Yin and reconciling five organs in an assistant manner; angelica sinensis and achyranthes bidentata are adopted for removing extravasated blood, generating new blood, and invigorating Qi and blood; all the materials cooperate with one another and coordinate with assistant materials, so as to enhance the efficacies of tonifying Qi and promoting blood circulation.

The invention discloses volume-adjustable auxiliary equipment directly connected with ventricles. The volume-adjustable auxiliary equipment comprises an inelastic shell, a ventricular auxiliary film, an adjustable lining film, a heart protection cover, an air sac joint, a sealing metal block, an upper sealing ring, a lower sealing ring and a plurality of screws. The volume-adjustable auxiliary equipment disclosed by the invention can be self-adaptive to hearts with different sizes, the severe impact of a gas pump can be transferred to the heart to be aided through the buffer of an adjustable chamber, and only the left and right ventricles are squeezed, thereby protecting the apex and other parts easy to be damaged. Compared with the prior art, the volume-adjustable auxiliary equipment is simple and reliable in integral design structure.

The invention relates to a preparation method and a purpose of a mitofilin gene knockout mice model. Specifically, the invention provides a preparation method of a mitofilin heterozygote mice model, and a purpose of mitofilin as a latent heart protection factor in medicament preparation.

The invention discloses an application of amygdalin for ischemia heart protection. The uses are based on the discovery and confirmation of the novel functions of the amygdalin: the amygdalin can relieve myocardial ischemia / reperfusion injury, and particularly has the effect of enhancing insulin to activate ''survival signal'' path central molecule Akt. Insulin resistance is a common soil of cardio-cerebrovascular diseases such as diabetes, hypertension, and coronary heart disease and is mainly manifested as the defect of ''survival signal'' path signal transduction taking the Akt as a central link. Therefore, the amygdalin capable of enhancing the Akt activation effect of the insulin can be used for the assistant treatment of insulin-resistance-based diseases, may have wide potential application prospect such as developing a health product or drug rich in the amygdalin, and can be beneficial to the health care of the common people and particularly for the prevention of insulin-resistance-based cardiovascular diseases.

The invention discloses application of niclosamide and a structural trim thereof in heart protection, pulmonary hypertension resistance and tumor resistance. The structural trim is an N-(2-hydroxypropyl) methacrylamide (HPMA) copolymer-Niclosamide conjugate (HPMA-Nic) obtained by modifying niclosamide with N-(2-hydroxypropyl) methacrylamide. A research shows that the niclosamide increases generation of ATP of the myocardial cells, resists doxorubicin-induced myocardial cell injury, inhibits the multiplication and collagen secretion of fibroblasts and inhibits the multiplication and migration of pulmonary artery smooth muscle cells. The HPMA-Nic obviously improves the water solubility of the niclosamide; and intraperitoneal injection can inhibit pressure load-induced mouse myocardial hypertrophy and inhibit growth of a tumor in a naked mouse body. The invention provides a new effective technical measure for myocardial protection, cardiac fibrosis resistance, myocardial hypertrophy resistance, heart failure resistance, pulmonary artery hypertension resistance and anti-tumor treatment, and the application has a wide application prospect.

The invention relates to an application of p-hydroxyphenylacetic acid in prevention and / or treatment of cardiovascular diseases. The invention finds for the first time that p-hydroxyphenylacetic acidhas a good treatment effect on vascular and cardiac injuries. For zebra fish interbody vascular (ISV) injury and subintestinal vein (SIV) growth conditions induced by a vascular endothelial cell growth factor receptor inhibitor (PTK787), p-hydroxyphenylacetic acid has a remarkable effect of promoting angiogenesis, and the generation number and the length of blood vessels can be obviously increased. The traditional Chinese medicine composition has a remarkable heart protection effect on heart failure of zebra fish induced by verapamil, arrhythmia induced by terfenadine and p-hydroxyphenylaceticacid, and can obviously reduce cardiac dilatation, relieve venous congestion and promote the heart rate to tend to be normal.

The present invention pertains to the field of biotechnology and medicine and discloses a usage of Heat Shock Protein 27(HSP27) in the heart protection aspect. The present invention firstly reveals that the HSP27 gene can be applied in the specific myofilament protein for stabilizing ischemia, heart failure and other damages of the heart muscle, so as to improve the contractile function of the heart muscle; the present invention also proves that the HSP27 transfected by the adenovirus vector can improve the contractile function of the heart with ischemia and can provide an effective new target for the treatment of heart diseases.

The invention relates to a method for extracting total alkaloid from rutaceae plant fruit fructus evodiae by adopting a supercritical extraction technology. Raw materials are pretreated in ways of raw material pulverization, screening, ultrasonic assisting, and the like; and effective components of the fructus evodiae are extracted by adopting anhydrous ethanol as an entrainer through applying a supercritical fluid technology. The method is simple and rapid and can be used for effectively extracting the alkaloid in the rutaceae plant fruit. The concrete application condition comprises the extracting pressure of 19-21MPa, the extracting temperature of 30-40 DEG C, the extracting time of 120-150 minutes and the CO2 flow of 2.0-3.0L / minute. The evodiamine is the main alkaloid in the plant and has various pharmacological activities of tumor resistance, nociception resistance, weight loosing, heart protection, blood pressure reduction, and the like.

The invention discloses a fresh flower cake and a making method thereof. The making method comprises the steps that 1, egg liquid, sugar, cake oil and baking powder are evenly stirred to form a mixture; 2, the mixture, flour, milk powder, edible salt, chocolate powder, rose petals, glycerinum and water are mixed, poured into a mold, baked, cooled and subjected to heat seal to obtain the fresh flower cake, wherein according to the stirring conditions, the rotating speed is 700-900 r / min, the stirring temperature is 40-50 DEG C, and the stirring time is 5-10 min. The fresh flower cake made through the making method is soft, fragrant and sweet in taste, has abundant multi-source phenol compounds and makes a great contribution to heart protection.

A nano-pharmaceutical formulation, comprising pumpkin seed oil; D-α-tocopheryl polyethylene glycol succinate (TPGS); and polyethylene glycol (PEG) 200 is provided. Additional cardioprotective therapies such as quercetin may be included in the formulation. Methods of treating cardiac dysfunction by administering the formulation are also provided.

The invention relates to a method for producing a haw calcium supplement, which comprises the following steps of: firstly, screening fine sands and dusts of Chinese medicine haw, selecting and removing mouldy haw and sundries, putting the haw into a ceramic boiler, adding water, slightly boiling three times, combining obtained juices, filtering and metering; secondly, neutralizing by using calcium carbonate with an edible specification; thirdly, evaporating and concentrating into juices with different concentrations by using indirect stream, or drying into dry powder by using a spray drying method; and fourthly, processing and preparing into oral solutions, fluid extracts, medicinal extracts, syrups, granules, capsules, pills, tablets and powder supplied for oral use. The invention has the advantages that the haw calcium supplement has both the calcium supplementing effect and the functions of haws, such as cholesterol and blood pressure reduction, heart protection and cardiovascular disease prevention; and the haw calcium supplement can increase gastric secretion, promote digestion and can be processed easily with low cost.

The invention provides a health-care tea for reducing blood fat and a preparation method thereof. The health-care tea comprises the compositions of raw materials in portions by weight: 10-15 portions of tea leaves, 10-15 portions of mulberry leaves, 10-15 portions of gynostemma pentaphylam, and 3-5 portions of American ginseng. In preparation, the compositions are crushed, then sieved, sterilized and packed, and each bag is packed by 5g. In the invention, the raw materials of the health-care tea for reducing blood fat are easy to obtain, the preparation of the tea is convenient, and the health-care tea has the functions of reducing blood fat, refreshing, improving immunity, being beneficial to heart protection, promoting longevity and preventing aging.

The invention discloses a head, neck, shoulder and heart pressure reduction protection pad according with human engineering, and relates to the field of beddings. The head, neck, shoulder and heart pressure reduction protection pad comprises a pillow body and a pad body; the pillow body comprises a high neck pillow region, a low neck pillow region and a head pillow region; the head pillow region is positioned between the high neck pillow region and the low neck pillow region, and the head pillow region respectively form an S shape with the high neck pillow region and the low neck pillow region; positions at both sides of the high neck pillow region and the low neck pillow region form side lying regions, and the middle positions of the high neck pillow region and the low neck pillow regionform a supine region; the pad body comprises a transverse shoulder protection region, a heart protection region and scapula and elbow protection regions; the transverse shoulder protection region is arranged at one end of the pad body, which is close to the pillow body, traverses the entire pad body width and is of a convex shape; the heart protection region directly faces a position from the neckto the middle of the back when a human body lies supine; the scapula and elbow protection regions are positioned at both sides of the pad body and correspond to scapula and elbow positions of the human body; and the pad body is connected in a detachable mode with the pillar body by a pillow pad connection piece. The head, neck, shoulder and heart pressure reduction protection pad respectively carries out targeted protection on positions of the head, the shoulders, the neck, the middle of the back and the like of the human body, and can adapt to different sleeping habit demands of customers.

The invention relates to an application of tetrahydroberberrubine in preparation of a heart protection medicine. Pharmacological experiments of tetrahydroberberrubine show that tetrahydroberberrubine can significantly improve cardiac dysfunction induced by pressure load, and has an obvious heart protection effect; and meanwhile, myocardial cell hypertrophy and interstitial fibrosis can be remarkably inhibited, the heart remodeling process is prevented, and the heart is prevented from entering the heart failure stage. In addition, the tetrahydroberberrubine compound is high in bioavailability, low in toxicity, stable and easy to produce, transport, store and take, and is a heart protection medicine with a wide application prospect.

The invention belongs to the field of acupuncture devices, and particularly relates to acupoint stimulation clothing with laser stimulation acupoint combination and a running method thereof. The acupoint stimulation clothing comprises an acupoint stimulation clothing body. The acupoint stimulation clothing body is internally provided with a stimulation module and a control module. The control module is electrically connected with the stimulation module. The stimulation module comprises a keep living stimulation module, a heart protection stimulation module, a spleen tonifying stimulation module, and a bone strengthening stimulation module. The keep living stimulation module, the heart protection stimulation module, the spleen tonifying stimulation module, and the bone strengthening stimulation module are separately electrically connected with the control module. For physical characteristics of middle-aged and elderly people and sub-healthy people, the acupoint stimulation clothing establishes systematic acupoint stimulation combination to provide security for maintenance of health of the middle-aged and the elderly people and the sub-healthy people.

The invention relates to a medical apparatus, namely an antihypertensive heart guard apparatus. The apparatus comprises a pendant line which is connected with a shell; the shell is provided with a communicated therapeutic circuit and a detecting circuit, and the pendant line is communicated and connected with the therapeutic circuit and the detecting circuit; a therapeutic pole that is communicated and connected with the neck area of a human body is connected in the pendant line; one surface of the shell is provided with a therapeutic pole that is connected with the chest surface of the body, and the therapeutic pole is connected with the therapeutic circuit at the same time; the other surface of the shell is further provided with a detecting pole that forms a circuit with the therapeutic pole on the pendant line when touched by a human hand, and the detecting pole is connected with the detecting circuit. The apparatus has the advantages of convenient use, easy consistent use, being beneficial to popularization and obvious effect, and is an ideal subsidiary apparatus for lowering blood pressure, relieving chest distress, chest pain and arrhythmia and preventing myocardial infarction, etc.

The invention relates to a berberine derivative as well as a preparation method and application thereof. The berberine derivative disclosed by the invention is remarkable in myocardial ischemia resisting effect, feasible and reasonable in preparation route, relatively low in cost, relatively low in toxic and harmful reagent consumption, free from environmental pollution and suitable for large-scale industrial production. According to the berberine derivative with heart protection activity and the preparation method of the berberine derivative, a basis can be effectively provided for developing a new heart protection medicine, the economic benefit in the future is huge, the wide social benefit can be generated, and the application prospect is wide.

The invention provides blood pressure reducing noodles. The formula of the blood pressure reducing noodles comprises the following components in parts by weight: 100-200 parts of wheat meal, 10-25 parts of oat meal, 1-5 parts of ginkgo seeds, 1-10 parts of wolfberry, 1-10 parts of semen cassiae, 3-10 parts of ginkgo leaves, 1-5 parts of lotus leaves, 1-5 parts of corn stigma and a proper amount of salt and water. According to the blood pressure reducing noodles and the preparation method thereof provided by the invention, without any gluten fortifier, thickening colloid or preservative, the food safety is guaranteed; and since multiple traditional Chinese medicine components are adopted in the formula of the blood pressure reducing noodles, the blood pressure reducing noodles have the functions of reducing blood fat and blood pressure, improving vascular elasticity and preventing blood coagulation and are perfect heart protection products.

The invention relates to a composite multi-functional three-dimensional heart protection cover. According to the scheme, the composite multi-functional three-dimensional heart protection cover comprises a non-elastic airtight outer cover, wherein the shape of the non-elastic airtight outer cover is matched with that of a heart; an opening is formed in the upper portion of the non-elastic airtight outer cover; a medical elastic silica gel layer is arranged in the outer cover; an air vent is formed in the outer cover and is connected with space between the outer cover and the medical elastic silica gel layer; a ventilating cover which covers the air vent is arranged on the inner side surface of the outer cover; the air vent is connected with a device capable of sucking and inflating continuously; an ice blanket is adhered to the inner side of the medical elastic silica gel layer; a temperature-measuring electrode is arranged on the inner layer of the ice blanket; a cloth layer is adhered to the inner layer of the ice blanket; a plurality of pace-making electrodes are distributed on the inner side surface of the cloth layer; wires of the pace-making electrodes are placed between the cloth layer and the ice blanket; and ends of the wires extend out of the outer cover via a combined position between the cloth layer and the upper portion of the ice blanket. Pressure is applied to the heart of a patient and released from the heart of the patient continuously with the aid of gas, electrophysiological levels of the patient can be monitored from a plurality of portions of the patient, required electrical stimulation can be given to the patient, and the temperature of the heart of the patient can be constant in a surgery process.

The invention belongs to the field of healthcare products and relates to a maca-coffee composition. The maca-coffee composition is composed of, by weight, 40% of maca, 7% of Poria Cocos, 3% of Semen Cassiae and 50% of coffee. The maca-coffee composition has efficacies of physical ability improvement, fatigue resistance, internal secretion regulation and balancing, fertility improvement, cardiac muscle enhancement, heart protection, heat clearing, eyesight improvement, constipation resistance, detoxification, stasis removal and tumor resistance and reduces negative effects of coffee while coffee flavor is kept.

The invention relates to the field of drug design and medicinal chemistry, in particular to a steviol derivative, a preparation method thereof and application of the steviol derivative in preparation of heart protection drugs. The steviol derivative is a compound shown as a formula I or a pharmaceutically acceptable salt thereof, and a solvent compound, an enantiomer, a diastereoisomer and a tautomer of the compound shown as the formula I or the pharmaceutically acceptable salt thereof or a mixture of the solvent compound, the enantiomer, the diastereoisomer and the tautomer in any proportion, including a racemic mixture. The derivative can effectively treat zebrafish morphological distortion and cardiac insufficiency caused by DOX, protects death and damage of myocardial cells by inhibiting excessive generation of active oxygen and recovering mitochondrial membrane potential, has remarkable heart protection activity, and can be used as a lead compound for treating cardiovascular diseases. Formula I.