The invention provides a water-free live keeping box, which is arranged in a liner of a refrigeration household appliance and can be drawn and pulled inside and outside relative to the liner; the live keeping box is provided with a box body, an opening, a sealing cover, a temperature control module, a humidity control module, a gas control module, a discharge substance removal mechanism and a control system, wherein the opening is formed in the box body, the sealing cover is used for opening or sealing the opening, the temperature control module is used for controlling temperature in the live keeping box, the humidity control module is used for regulating humidity in the live keeping box, the gas control module is used for regulating oxygen concentration in the live keeping box, and the discharge substance removal mechanism is used for removing discharge substances of aquatic products. The water-free live keeping box provided by the invention is used for storing the aquatic products, and the temperature, the humidity, the oxygen concentration and the like in the live keeping box are regulated through the temperature control module, the humidity control module, the gas control module and the discharge substance removal mechanism further so as to build a suitable environment for keeping the aquatic products live under the water-free condition, and therefore the aquatic products can be kept live under the water-free condition for more than three days, and the use requirements of ordinary families are met.