116 results about "Cyclopentenone" patented technology

The invention relates to a method for preparing aromatic hydrocarbon and cyclopentenone from biomass derivative gamma-valerolactone by catalytic conversion, which comprises the following steps: (1) using biomass derivative gamma-valerolactone as a raw material, which is prepared by carrying out hydrogenation reaction on levulinic acid; (2) introducing one or more transition metals into a zeolite molecular sieve, and preparing a reaction catalyst at the reaction temperature of 350-550 DEG C by using a fixed bed or fluid bed as a reactor; (3) in an inert or reducing atmosphere, carrying out contact reaction on the raw material gamma-valerolactone and catalyst under the reaction pressure of 0-10 MPa; and (4) after the pyrolysis gas is condensed, collecting the liquid product in the condensation receiver, thereby obtaining the aromatic hydrocarbon product (of benzene, toluene and xylene) and the cyclopentenone product. By using the renewable biomass derivative gamma-valerolactone as the raw material, the method has the advantage of milder reaction conditions, and the catalyst is simple to prepare and easy to recover and reuse.

The invention provides a method for synthesizing methyl dihydrojasmonate. 2-pentyl cyclopentenone is adopted as a raw material; the raw material and allyl zinc bromide are subjected to 1,4-Michael addition to form 2-pentyl-3-allyl cyclopentanone; the 2-pentyl-3-allyl cyclopentanone is oxidized by sodium periodate in the presence of a ruthenium trichloride hexahydrate catalyst to synthesize dihydrojasmonic acid; and then the dihydrojasmonic acid is esterified to form the methyl dihydrojasmonate. The raw material of the method is cheap and low in cost; the process is simple and convenient in operation; the reaction conditions are mild and easy to control; the synthesis route is short and the synthesis period is reduced greatly; and the reaction product is single, high in yield (up to 65 to 85 percent), less in environmental pollution, and environmentally-friendly.

The present invention provides the synthesis process of cyclopentadiene or substituted cyclopentadiene, and features that during the catalytic reduction reaction of producing cyclopentadiene or substituted cyclopentadiene with cyclopentenone or substituted cyclopentenone, Lewis acid is used to raise the yield of cyclopentadiene or substituted cyclopentadiene greatly and simplify the technological process.

The invention discloses a novel fluorocyclopentenone preparation method and a product thereof. The novel fluorocyclopentenone preparation method is characterized by comprising the following step: methyl tert-butyl ether, enynic ester, gold (acetonitrile)[(2-biphenyl)di-tert-butylphosphine] hexafluoroantimonate (I) and N-fluorobenzenesulfonimide are added to react, so that fluorocyclopentenone is obtained. The novel method for preparing a fluorocyclopentenone compound which is provided by the invention ensures that an enynic ester compound can be converted into the fluorocyclopentenone compound. The whole reaction is carried out under normal temperature and normal pressure, conditions are mild, and energy consumption is low. The whole reaction is carried out by utilizing a one-pot method, operation is easy, yield is high, and the purity of the product is 98 percent or more. The reaction substrate range is wide, and not only the simple enynic ester compound but also complex compounds containing natural product groups are applicable. The developed fluorocyclopentenone compound has potential bioactivity, and can become a drug by subsequent testing or modification.

The invention provides a preparation method of chiral 4-amino-cyclopentenone. The preparation method comprises the following steps: providing 2-furanyl shown in formula 1, aromatic amine shown in formula 2 and a catalyst CPA, wherein the CPA is phosphoric acid of 1-pyrenyl substituted chiral spiro skeleton; dissolving the aromatic amine and the CPA in a first organic solvent; cooling to 0-5 DEG C; adding a solution of a first organic solvent of 2-furanyl; and performing asymmetric intermolecular azepine Piancatelli rearrangement reaction under a condition of stirring at room temperature to obtain chiral 4-amino-cyclopentenone shown in formula 3. The obtained chiral 4-amino-cyclopentenone can be diversely prepared into chiral amino-substituted cyclopentanone, cyclopentenol, lactone and other structures through chemical conversion.

This invention is a high-effective high-steroselectivity synthetic method for multi-substituted 3-cyclopentene-1-ketone. It is incldues the following steps: firstly, the derivative of 1,4-diiodo-1,3-butadiene dissolved in the solvent of ethyl ether or tetrachlorofuran reacts with n-butyl lithium or tert-butyl lithium under low temp., CO is further introduced,l quenching reaction is conducted, andthe pure product is obtained further through extracting, stripping, drying, concentrating and decontaminating. The said invented method is scientific and rational, is a most direct and most simple method, and the yield is high, and the product is easily decontaminated.

The invention discloses a method for preparing S-type cyclopentenone from a sol gel embedded immobilized enzyme. The method comprises the following steps: 1) using an organic silane reagent as a precursor to react with water under the catalysis of acid or alkali so as to generate a sol; 2) adding a buffer solution containing enzyme powder into the mixture, and mixing, keeping stand for aging, and drying the mixture to obtain the sol gel embedded immobilized enzyme; and 3) using the sol gel embedded immobilized enzyme as a catalyst to perform enantiomeric separation reaction with cyclopentenone in an organic phase so as to obtain the S-type cyclopentenone. The method is characterized in that the used lipase is Pseudomonas aeruginosa, Arthrobacter sp. and Acinetobacter sp.; the precursor is gamma-methacryloyl-oxypropyl-trimethoxysilane or alkyl-trimethoxysilane, or a mixture of the gamma-methacryloyl-oxypropyl-trimethoxysilane or the alkyl-trimethoxysilane and n-methyl silicate or ethyl orthosilicate; and the cyclopentenone is allyl alcohol ketone or propargyl alcohol ketone. The vitality, the stability, the enantioselectivity and the like of the immobilized enzyme related in the invention are significantly improved in the split reaction of the cyclopentenone.

The invention relates to a method for preparing JP-10 aviation fuel from furfuryl alcohol. The method for preparing JP-10 aviation fuel by taking the furfuryl alcohol as a raw material is totally divided into six reactions as follows: a first reaction of carrying out a rearrangement reaction on a furfuryl alcohol solution in the presence of a base catalyst or under the condition that any catalystis not added to prepare hydroxy cyclopentenone; a second reaction of reacting the hydroxy cyclopentenone and hydrogen under catalysis of a hydrogenation catalyst so as to prepare 1,3-cyclopendiol; a third reaction of dehydrating the 1,3-cyclopendiol to prepare cyclopentadiene; a fourth reaction of carrying out a D-A reaction on the cyclopentadiene to produce dicyclopentadiene; a fifth reaction ofhydrogenating the dicyclopentadiene to produce endo-tetrahydrodicyclotadiene; and a sixth reaction of performing isomerization on the endo-tetrahydrodicyclotadiene to produce hanging type tetrahydrodicyclopentadiene, wherein the prepared hanging type tetrahydrodicyclopentadiene can directly serve as the JP-10 aviation fuel. The invention provides a cheap high-efficiency synthetic method for synthesizing the JP-10 aviation fuel from a lignocelluloses-based platform chemical compound, namely furfuryl alcohol.

The invention relates to a process for the preparation, in a single step, of substituted 2-cyclopenten-1-ones by reacting a substituted enone with an aldehyde in the presence of a catalytic system. The catalytic system consists of a metal complex, such as a Ti(Cl)3(alkoxy), and a co-ingredient, such as a carboxylic acid anhydride or an anhydrous salt.

The present invention provides a method for efficiently producing a 2-alkyl-2-cyclopentenone as well as a method for producing a jasmonate derivative by using the same. That is, in the present invention, the compound (2) is obtained by reacting an amine and a hydrogen halide with the compound (1) at a specific ratio to carry out isomerization reaction or by reacting a catalyst comprising an amine and a hydrogen halide with the compound (3) to carry out dehydration-isomerization reaction. Further, this compound (2) is reacted with a malonic acid diester and then reacted with water to obtain a jasmonate derivative (5): wherein each of R1 and R2 represents H, a C1-8 alkyl group or the like, and R3 represents a C1-3 alkyl group.

The present invention relates to novel processes for preparing optically active Cyclopentenones of Formula (R)-1,

which are useful for the preparation of Prostaglandins and analogs thereof. The invention also relates to novel Cyclopentenones prepared from the processes.

The invention discloses a synthetic method of methyl dihydrojasmonate or an intermediate thereof, which comprises the following steps: under the action of a supported catalyst, carrying out Michael addition reaction on 2-pentylcyclopentenone and methyl acetate or dimethyl malonate to obtain the methyl dihydrojasmonate or the intermediate thereof, the supported catalyst comprises a carrier and an active component supported on the carrier; the active component is quaternary ammonium base, and the carrier is a modified molecular sieve; the modified molecular sieve is obtained by modifying a molecular sieve with propylene glycol methyl ether acetate. According to the synthesis method, a super-strong base or strong base catalyst which is extremely unstable and has harsh reaction conditions in the prior art is replaced, reaction steps are reduced, the reaction conditions tend to be mild, and the reaction safety is improved. The invention further discloses a catalyst used in the synthesis method.

Crystals of trans-4,5-dihydroxy-2-cyclopenten-1-one of an alpha-type.

The invention discloses a 2-trifluoromethyl-containing cyclopentenone derivative with a structure shown in a formula I and a preparation method of the 2-trifluoromethyl-containing cyclopentenone derivative. Copper cyanide, a Togni reagent, potassium carbonate and an acetylenic ketone compound are added into a reaction system, the reaction system is formed in a certain reaction environment, and after the reaction is completed, post-treatment is performed to obtain the 2-trifluoromethyl-containing cyclopentenone derivative. According to the method, carbonyl is adopted as a guiding group, a cyclopentenone ring skeleton structure is synthesized on the basis of a free radical tandem cyclization reaction strategy, construction of a series of complex 2-trifluoromethyl cyclopentenone is efficiently achieved, the reaction yield is medium to good, operation is easy, and a new way is provided for synthesis of cyclopentenone compounds.