225 results about "2-Butanol" patented technology

Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.

Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein.

Methods for the fermentive production of four carbon alcohols are provided. Specifically, butanol, preferably 2-butanol is produced by the fermentive growth of a recombinant bacteria expressing a 2-butanol biosynthetic pathway. The recombinant microorganisms and methods of the invention can also be adapted to produce 2-butanone, an intermediate in the 2-butanol biosynthetic pathways disclosed herein. Specifically disclosed herein are the use of coenzyme B12-independent butanediol dehydratases that catalyzes the substrate to product conversion of 2,3-butanediol to 2-butanone in the process of producing 2-butanol and 2-butanone.

A method for the production of 2-butanol by fermentation using a microbial production host is disclosed. The method employs a reduction in temperature during the fermentation process that results in a more robust tolerance of the production host to the butanol product.

The present invention relates to a method for removing carbon dioxide (CO2) from a gas stream. Particularly, the present invention relates to a method for removing CO2 from a gas stream by a liquid absorbent having an amino alcohol derived from 4-amino-2-butanol. In comparison to conventional amines, the amino alcohols of the present invention have been found to provide a higher CO2 absorption capacity and a higher cyclic capacity for CO2 removal.

A process for the preparation of an organosilicon condensate which comprises reacting together a silicon containing compound having at least one silanol group and a silicon containing compound having at least one —OR group or at least one silanol group (or a compound having both groups) in the presence of strontium oxide, barium oxide, strontium hydroxide or barium hydroxide and optionally a solvent such as water, methanol, ethanol, 1-propanol, 2-propanol, 1-butanol and 2-butanol, acetone or toluene.

The present invention discloses a process for devulcanizing cured rubber into devulcanized rubber that is capable of being recompounded and recured into useful rubber products, said process comprising heating the cured rubber to a temperature which is within the range of about 150° C. to about 300° C. under a pressure of at least about 3.4×106 Pascals in the presence of a mixture of carbon dioxide and 2-butanol.

Embodiments of the invention relate to the enzymatic conversion of bioderived feedstocks to commercially valuable chemicals. The enzymatic conversions of the embodiments of the invention offer the potential for lower cost routes to these value-added chemicals. Some of the chemicals that are useful include nylon intermediates such as caprolactam, adipic acid, 1,6-hexamethylene diamine; butanediols such as 1,4-butanediol, 1,3-butanediol, and 2,3-butanediol; butanols such as 1-butanol, and 2-butanol; succinic acid, butadiene, isoprene, and 3-hydroxypropanoic acid.

The invention relates to a process for producing alcohol and selectively co-producing 2-butanol by hydrogenising acetate and a matching process system thereof. After industrial acetate is hydrogenised and purified, a product is rectified, purified and dehydrated, thereby obtaining alcohol and co-producing 2-butanol. Cu-Zn-M is taken as an active component of a catalyst adopted in the process, wherein M is selected from the compound of one and more of Ir, Mn, W, Ru and Zr. 2-butanol is selectively co-produced by adjusting the reaction temperature. The catalyst, process and device adopted by the invention have the characteristics of high activity, high selectivity, high yield, strong market adaptability, less equipment investment, environmental protection, simpleness in preparing process, economical and practical properties, and the like. Meanwhile, conversion per pass is high and reaction heat is effectively utilized, so that the load for separating rough products is greatly relieved, the production flow is shortened and the energy consumption of production is also greatly reduced.

A nanometre-sized modified special rust-inhibiting primer is characterized in that it includes the following components (mass %): 29.0-60.0 % anti-corrosive paint host, 1.0-10.0 % nano oxide addition,5.0-15.0 % curing agent and 30.0-65 % diluent. The said anti-corrosive paint consists of rust-preventive material, coloring pigment, compounded resin and auxiliary agent, the curing agent is compounded by 75 % aromatic isocyanate, dimethylbenzene, butyl acetate, propanol and 2-butanol and the diluent is combination of alcohol and ester solvent. The invention has conducted adequate optimization and association for the components of the rust-inhibiting primer and its proportioning, which has largely reduced the contents of the toxic substance and the harmful substance in the total weight of the products, not only can guarantee the champion cryogenic film-forming property, but also can reduce the degree of pollution to the environment, which can effectively support the health of the maker, the user and the surrounding people, fitting requirement of the environmental protection, simultaneously can further improved the quality of the rust-inhibiting primer.

This invention is intended to produce 2-butanol with excellent productivity via a fermentation process. Recombinant microorganisms into which the acetoacetyl-CoA synthase gene and a group of genes (i.e., genes involved in 2-propanol synthesis) encoding a set of enzymes synthesizing 2-propanol from acetoacetyl-CoA have been introduced are cultured, so that, in addition to 2-propanol, 2-butanol is produced at a high level in a medium.

A non-naturally occurring microbial organism has at least one exogenous nucleic acid encoding a MEK pathway enzyme expressed in a sufficient amount to produce MEK. The MEK pathway includes an enzyme selected from an acetoacetyl-CoA dehydrogenase (bifunctional), an acetoacetyl-CoA aldehyde dehydrogenase, a 3-oxobutyraldehyde reductase, a 3-oxobutanol dehydratase, an MEK oxidoreductase, a 3-oxobutyraldehyde aminotransferase, a 4-aminobutan-2-one deaminase, a 2-amino-4-ketopentanoate (AKP) thiolase, an AKP aminotransferase, a 2,4-dioxopentanoate decarboxylase, an AKP deaminase, an acetylacrylate decarboxylase, an AKP decarboxylase, a glutamate dehydrogenase, a 3-oxobutyraldehyde oxidoreductase (aminating) and an AKP oxidoreductase (aminating). A 2-butanol pathway further includes an MEK reductase. A method for producing MEK or 2-butanol includes culturing these organisms under conditions and for a sufficient period of time to produce MEK or 2-butanol.

The present invention relates to a process for separating 2-butanol from tert-butanol / water mixtures using a membrane to reduce a water concentration to less than the limit concentration of the distillation boundary line connecting the two azeotropes TBA / water and SBA / water and is subsequently worked up by distillation.

The invention relates to a technique method of the continuous production of 2-butanol by the direct hydration of n-butene, belonging to the technical field of petrochemical industry. The invention comprises the steps that under the existence of the catalyst of strong acid ion exchange resin, fresh raw material of the n-butene and a cycling n-butene are mixed up and enter a hydration reactor for a hydration reaction, and then enter a separation unit of crude products for separation; a refining unit of the n-butene is additionally arranged; one part of the unreacted n-butene which is separated from the separation unit of crude products is used as the cycling n-butene and is returned to the hydration reactor for further hydration reaction and the other part is sent to the refining unit of the n-butene for the rectification and n-butene is recycled after the removal of butane to be used as the fresh raw material of the n-butene continually. The method has the advantages of improving recycling, improving the volumetric efficiency of the hydration reactor, improving the yield of 2-butanol greatly, reducing ineffective circulation and reducing the consumption of energy, thus realizing the zero discharge of the n-butene with high yield and low energy consumption.

The invention discloses mixed stewed pork essence which consists of furanone, ethyl maltol, 2-acetylpyrazine, methyl cyclopentenolone, difurfuryl sulfide, 3-sulfydryl-2-butanol, 2-methyl-3-furan mercaptan, di(2-methyl-3-furan mercaptan)-disulfide, methyl(2-methyl-3-furan mercaptan)-disulfide, acetic acid, 3-sulfydryl-2-butanone, 3-propionaldehyde, thiophane-3-acetone, 2,3,5-trimethyl pyrazine, counter,counter-2,4-decadiene aldehyde, furfuryl disulfide, furfurylmercaptan, anise camphor, anisic aldehyde, pepper essential oil, 2-acetyl thiazole, delta-dodecalactone, 4-methyl-5(beta)-hydroxyethyl thiazole acetate, onion oil alcohol, 4-methyl-4-bran sulfenyl-2-pentanone and glycerol triacetate. The mixed stewed pork essence is high in biofidelity and mellow and fine in fragrance, has a good application effect and is economical and practical.

An object is to provide a process for producing the compound of formula 1 in higher yield by the ring-opening addition reaction of epoxytriazole with amine under mild conditions without using a large excess of 4-methylenepiperidine. The process for producing (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol or an acid addition salt thereof comprises reacting (2R,3S)-2-(2,4-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane with an acid addition salt of 4-methylenepiperidine in a reaction solvent in the presence of a hydroxide of an alkali metal or an alkaline earth metal selected from the group consisting of lithium, sodium, calcium, and strontium, or a hydrate thereof.

The invention discloses a soil-improvement special slow release fertilizer for rice. The soil-improvement special slow release fertilizer for rice comprises 30-45wt% of powdery urea, 20-40wt% of urea phosphate, 8-15wt% of potassium chloride, 15-30wt% of a potash magnesium sulfate fertilizer, 2-8wt% of zinc humate, 1-6wt% of manganese humate, 1-5wt% of urea iron humate, 0.005-0.02wt% of compound sodium nitrophenolate, 1-5wt% of a slow release agent and 1.99-6wt% of an auxiliary material, wherein the slow release agent contains 5-15wt% of N-methylolacrylamide, 10-30wt% of an unsaturated polyester resin, 4-10wt% of cyclohexanol, 5-13wt% of 2-butanol, 1-5wt% of talcum powder, 1-4wt% of kaolin, 1-6wt% of ethyl cellulose, and the balance distilled water. The invention also discloses a preparation method of the soil-improvement special slow release fertilizer for rice.

An object is to provide a process for producing the compound of formula 1 in higher yield by the ring-opening addition reaction of epoxytriazole with amine under mild conditions without using a large excess of 4-methylenepiperidine. The process for producing (2R,3R)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol or an acid addition salt thereof comprises reacting (2R,3S)-2-(2,4-difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane with an acid addition salt of 4-methylenepiperidine in a reaction solvent in the presence of a hydroxide of an alkali metal or an alkaline earth metal selected from the group consisting of lithium, sodium, calcium, and strontium, or a hydrate thereof.

The invention provides a method for industrial production of a butoconazole nitrate intermediate, that is 1-chloro-4-p-chlorophenyl-2-butanol (a compound in formula II). The method of the invention comprises: 1. a Grignard reaction, that is, adopting p-chlorobenzyl chloride as a raw material, and performing a Grignard reaction with magnesium powder in a mixed solvent of methyl tertiary butyl ether and tetrahydrofuran; 2. a condensation reaction, that is, continuing reaction by adding epichlorohydrin to obtain the compound II which is an important intermediate for preparing butoconazole nitrate. According to the method, the raw materials are cheap and easily available, the reaction solvent is safer, and the method is suitable for industrial production.

The invention relates to a method for synthesizing glycol ether ester. The method comprises the following steps that: glycol ether and fatty acid as raw materials are directly esterified and synthesized into glycol ether acetic ester at a temperature of between 80 and 180 DEG C in the presence of an acidic catalyst and an azeotropic dehydrating agent; and the acidic catalyst is paratoluenesulfonic acid or methanesulfonic acid, and dosage of the catalyst is 0.05 to 1 percent of total weight of reaction materials. The method is characterized in that the mol ratio of the fatty acid to the glycol ether is 1.0:0.8-1.5; and the azeotropic dehydrating agent is isobutyl acetate or 2-butanol acetate, and dosage of the azeotropic dehydrating agent is 5 to 30 percent of the total weight of the reaction materials. The method has the advantages that compared with butyl acetate, the azeotropic dehydrating agent used in the reaction has a lower boiling point and a lower azeotropic point, smaller solubility and lower hydrolysis speed, so that energy consumption during reacting and reclaiming the azeotropic dehydrating agent can be reduced, the reaction speed is improved, and water entrainment of a side product is reduced.

The invention relates to a method for producing 1,4-butanediol, tetrahydrofuran, gamma-butyrolactone and butanol. According to the technical scheme, double-esterification reaction is carried out in an esterification unit by virtue of the combination of a fixed bed reactor and a catalysis distilling tower; tetrahydrofuran is separated out of a reaction product, then butanol is separated out of the reaction product by using a butanol unit, a part of 1,4-butanediol with acetal is firstly separated out of a material flow containing 1,4-butanediol and gamma-butyrolactone, so as to obtain a 1,4-butanediol product which meets the purity requirement; 1,4-butanediol which is discharged together with acetal is converted into gamma-butyrolactone through dehydrogenation reaction, and the gamma-butyrolactone is fed into a gamma-butyrolactone refining unit together with acetal, so as to separate the acetal from the gamma-butyrolactone. The method can solve the problems in the prior art very well and can be applied to industrial production of 1,4-butanediol, tetrahydrofuran, gamma-butyrolactone and butanol.

The invention overcomes the technological difficulty that a single solvent is different to prepare a spherical crystal. The single solvent 2-butanol is adopted, and the amount and grain diameters of added clopidogrel hydrogen sulfate I crystal form spherical crystal are controlled, so that clopidogrel hydrogen sulfate is stably separated out from a solution system in a spherical crystal form in a specific powder form range, the obtained clopidogrel hydrogen sulfate spherical crystal has the characteristics of specific powder and has superior state in the aspects of solvent residue, bulk density and mobility, and the preparation method is beneficial for the realization of powder vertical compression preparation technology. The invention also further discloses a medicine composition containing the clopidogrel hydrogen sulfate I crystal form spherical crystal prepared and obtained through the technology.

The invention discloses a method partly replacing corn fermentation in acetone butanol production, including the following steps: raw material is prepared and boiled down for sterilization; when boiled mash is cooled down within a certain temperature range, strain is inoculated; after fermentation for a certain time, the mash is made into final acetone, butanol and ethanol products after filtration and distillation. The invention reduces the raw material cost in producing acetone butanol through adopting zymotechnics and eases the problem of high grain consumption; meanwhile, the invention increases the use value of B starch or B starch slurry in processors processing wheat flour, etc.

The invention discloses an aluminum alloy hub surface anodic oxidation treatment process which comprises the following steps: removing grease and oil on the surface of an aluminum alloy hub, washing with water for the first time, neutralizing, washing with water for the second time, oxidizing, washing with water for the third time, dyeing, washing with water for the fourth time, sealing, washing with water for the fifth time, performing thermal treatment, washing with water for the sixth time, and spraying golden oil. The process aims at performing anodic oxidation on the aluminum alloy hub, a cold water hole sealing method is adopted, and an anionic surfactant 2-butanol is added into a hole sealing liquid, so that the sealing effect is good. By spraying the golden hole on the surface of the hub, the hub has a surface which is glossy, smooth and clean in appearance, and thus the attractiveness is improved, and the service life of the hub is prolonged.

This invention is based upon the unexpected discovery that the surface of reclaimed rubber crumb particles can be devulcanized by heating the crumb particles to a temperature of at least about 150 DEG C. under a pressure of at least about 3.4x10<6 >Pascals in the presence of 2-butanol. It is further based upon the unexpected discovery that such surface devulcanized rubber crumb particles having a particle size within the range of about 325 mesh to about 20 mesh can be recompounded and recured into high performance rubber products; such as, tires, hoses and power transmission belts. This invention more specifically discloses a process for devulcanizing the surface of reclaimed rubber crumb into surface devulcanized reclaimed rubber crumb that is suitable for being recompounded and recured into high performance rubber products, said process comprising the steps of (1) heating the reclaimed rubber crumb to a temperature which is within the range of about 150 DEG C. to about 300 DEG C. under a pressure of at least about 3.4x10<6 >Pascals in the presence of 2-butanol to devulcanize the surface of the rubber crumb thereby producing a slurry of the surface devulcanized reclaimed rubber crumb in the 2-butanol, wherein the reclaimed rubber crumb has a particle size which is within the range of about 325 mesh to about 20 mesh, and (2) separating the surface devulcanized reclaimed rubber crumb from the 2-butanol.

A fuel composition including mixed butanols, such as for example, 2-butanol, iso-butanol and tert-butanol, preferably 2-butanol and tert-butanol is provided. Methods of preparing and using the mixed butanols composition as combustible neat fuels and / or oxygenate fuel constituents in gasoline, diesel, jet fuel, aviation gasoline, heating oil, bunker oil, and the like are also provided.

The invention relates to a formulated beef oily essence and a preparation method thereof. The essence comprises the following raw materials: 2-methyl-3-furanethiol, bis (2-methyl-3-furanethiol), 4-ethyloctanoic acid, furanone, octanoic acid, oleic acid, 2,3,5-trimethyl pyrazine, 5-methylfurfural, 3-(methylthio) propionaldehyde, 4-methyl-5-thiazoleethanol, 2, 6-dimethylpyrazine, 2, 3-butanedithiol, 2, 4-dimethyl thiazole, difurfuryl disulfide, eugenol, mace oil, onion oil, 2-acetylfuran, garlic oil, 4-ethylguaiacol, soy fouranone, 3-methylthiopropanol, butanedione, 3-sulfydryl-2-butanol and soybean oil. The prepared essence has an intense beef flavor, the flavoring effect in spicy and hot small foods is good, the stability of the fragrance and the flavor is very good and the fragrance and the flavor of the spicy and hot small foods can be kept to be very good within the quality guarantee period.

The invention provides an improved preparation method of (2R,3S)-3-(5-fluoropyrimidine-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazole-1-yl)-2-butanol(voriconazole), comprising the following steps: preparing a mixture of four enantiomers by using Reformatsky coupling reaction, then in the presence of residual zinc dust after the reaction, directly adding proper amount of acid to carry out hydrogenolysis dechlorination; splitting by directly using chiral acid to obtain chiral acid addition salts of a target compound with (2R,3S) configuration, and dissociating under alkaline conditions to obtain high-yield high-optical purity voriconazole. The method is safe, convenient and efficient, can fully utilize the residual zinc dust of the coupling reaction, and can save the steps of separating the enantiomers through hydrochloride production, alkalization, palladium-carbon catalytic hydrogenation dechlorination, thus the production process is greatly simplified, the product yield and production safety are raised, and simultaneously the production cost is greatly reduced.