The invention discloses biomedical
polysaccharide hemostatic and healing
sponge and a preparation method thereof, and belongs to the technical field of medical materials. The preparation method comprises the following steps: firstly, dissolving a
polysaccharide material
carboxymethyl cellulose,
hyaluronic acid or a mixture thereof into an alkaline solution, stirring sufficiently, and swelling into
colloid; secondly, adding a crosslinking agent into the
colloid, stirring sufficiently, incubating into uniform gel, and dialyzing and purifying the obtained gel; thirdly, adding glycerin into the purified product, stirring at a high speed for bubbling, and pouring into a lyophilizing disk; and finally, performing
freeze drying at a low temperature to obtain dehydrated
sponge. The hemostatic and healing
sponge prepared with the method is good in flexibility, do not drop crumbs, is strong in liquid absorption, can provide a wet environment to a wound, is non-stick to the wound, is good in
biocompatibility, is qualified in heavy
metal detection and endotoxin detection, is non-cytotoxic in a bio-safety test, is free of intradermal
irritation and
sensitization response, and has the functions of stopping bleeding rapidly, absorbing
exudate and promoting
wound healing.