The invention relates to the separation of microparticles by means of a
nozzle (12) for the release of a separating
stream (20), comprising at least one enveloping fluid and microparticles entrained Therein, with a vibration generator (18), for the dispersion of the separation flow (20) into a
droplet flow (20′), with a deflector device (24), for separation of the
droplet flow (20′) into a through flow (20A) and at least one side flow (20B, 20C, . . . ), depending on signals from an analytical device (38). Said analytical device (38) is provided for the analysis of the microparticles(s) contained in the droplets and to control the deflector device (24). Also provided is a protective chamber for product and personnel protection, in which at least the
nozzle (12), the oscillation generator (18) and the deflector device (24) are arranged. The analytical device is arranged essentially outside the microbiological safety cabinet (200), whereby, according to the invention, the protective chamber is part of a microbiological safety cabinet (MSW 200), in particular with a laminar throughflow, with a clean chamber (34) and with a monitoring device (22), provided in a side wall, in particular in the back wall (32) of the microbiological safety cabinet (200), through which the signals of the microparticles arising from the separating
stream (20) are supplied to the detectors of the analytical device (38), arranged outside the microbiological safety cabinet (200).