42results about How to "Reaction conditions are readily available" patented technology

The invention relates to an extraction method for odourless DHA oil. The method comprises the steps of: (1) fermentation: fermenting DHA containing Schizochytrium limacinum to obtain a fermentation broth; (2) fermentation broth dehydration: subjecting the fermentation broth to natural sedimentation, removing part of water in the fermentation broth, and taking the sedimentated concentrated liquid; (3) washing: using a ceramic membrane to conduct recirculating filtration on the concentrated liquid and performing washing; (4) cell wall breaking by a high pressure homogenizer; (5) dehydration treatment on the cell wall broken concentrated liquid; and (6) dissolution of the dehydrated concentrated liquid in an n-hexane solvent or a 95% ethanol solvent to perform extraction and desolvation so as to obtain DHA oil. The method provided by the invention greatly improves the taste and odor of DHA oil, reduces the wall breaking time, also improves the extraction efficiency and productivity of the extraction section, and is basically free of emulsification phenomenon, greatly saves the production cost, and improves production efficiency.

The invention relates to the field of lithium battery electrolyte additives and in particular to an economic preparation method suitable for industrially producing lithium difluorophosphate. The method at least comprises the following steps: (1), enabling an oxidized boron compound to react with lithium hexafluorophosphate, to obtain a lithium difluorophosphate mixture; and (2), concentrating thelithium difluorophosphate mixture, adding a poor solvent, crystallizing, and separating to obtain the lithium difluorophosphate.

The invention provides a method for synthesizing (E)-2-hexenoic acid. The method comprises the following steps: using ethyl malonate as a raw material, and performing Knovenagel reaction, hydrolysis and decarboxylation on the ethyl malonate in a water phase to synthesize the (E)-2-hexenoic acid. Aiming at problems of strict reaction condition, serious side reaction, low yield and usage of a toxicreagent in the prior method for synthesizing the (E)-2-hexenoic acid, the method uses water as a reaction medium to realize clean and environment-friendly production without pollution, and has accessible raw materials with low cost, mild reaction condition, simple operation and easy industrialization. The synthesis method has few side reactions, and yield up to 75 to 85 percent.

The invention relates to a method for preparing ethyl 2-oxo-4-phenylbutyrate, which comprises the following steps: (1) reacting beta-halogeno ethylbenzene with magnesium in a first aprotic solvent to obtain a Grignard solution containing a Grignard reagent; (2) reacting ethyl oxalyl monochloride with one or more of CuX, Li2CuX4 and CuCN.LiX in a second aprotic solvent to obtain a solution containing a copper acyl chloride salt compound; and (3) dropwise adding the Grignard solution in the solution obtained in step (2), persevering the temperature at -20-160 DEG C, enabling the Grignard reagent to react with the cooper acyl chloride salt compound to obtain a product solution after the reaction is finished, carrying out acidic hydrolysis and alkali neutralisation on the product solution in sequence, washing, drying and removing the solvent, and obtaining the ethyl 2-oxo-4-phenylbutyrate with the purity no less than 97% after high vacuum rectification. The invention has the advantages of good reaction selectivity, high yield, easily obtained raw materials, mild reaction conditions, convenient operation and low cost.

The invention discloses a molybdenum-boron / sepiolite catalyst and its preparation method and application. The molybdenum-boron / sepiolite catalyst includes sepiolite as a carrier and the active component loaded on the sepiolite molybdenum and boron. The molybdenum-boron / sepiolite catalyst of the present invention has a wide range of sources of raw material sepiolite, low cost, environmental protection, can effectively reduce depolymerization costs, and is suitable for large-scale industrial applications, and the molybdenum-boron / sepiolite catalyst of the present invention Cooperating with the supercritical system, the conversion rate of depolymerized lignin is high, the selectivity of substituted phenols and carboxylic acid compounds is high, and the catalyst can be recycled more than 50 times.

The invention discloses a synthetic method of a carbapenem antibiotic drug intermediate. By using (R)-3-hydroxybutyrate as the raw material, the carbapenem antibiotic drug intermediate 4-AA is prepared. Raw materials for the process are cheap and easily-available and can be purchased in quantity. The synthetic method has simple steps, yield of each step is high, and reactions are simple. By usinga chiral column as the split chiral center, use of a precious metals chiral reducing catalyst is avoided. the synthetic method of the invention has the following advantages: cost is low; yield is high; and reaction conditions are easily available.

The invention discloses an adapter-modified magneto-optic dual-function contrast agent and a preparation method and application thereof. The contrast agent comprises silicon dioxide-coated trimanganese tetroxide nanoparticles, wherein the diameters of trimanganese tetroxide nanoparticles are 6-8 nanometers; the thickness of a silicon dioxide coating layer is 8-12 nanometers; the surface of the silicon dioxide coating layer is provided with an amino group and is coupled with a rhodamine isothiocyanate molecule and dicarboxyl polyethylene glycol through the amino group; and the dicarboxyl polyethylene glycol is connected with an adapter with an amino group. The contrast agent obtained in the invention has high monodispersity, high biocompatibility and targeting property, can be taken as a good T1 magnetic resonance imaging contrast agent, has high targeting property on tumor cells, and has wide application value in the fields of medicaments and biology; and the preparation method provided by the invention has the advantages of very low requirements on equipment, convenient operation process, low prices of need raw materials and nuisanceless byproducts.