60results about How to "Novel dosage form" patented technology

The invention mainly relates to a wart treating medicament and a preparation method thereof. The wart treating medicament comprises the following major raw materials by weight: 6-70 grams of java brucea fruit, 5-70 grams of isatis root, 6-60 grams of glabrous greenbrier rhizome, 6-60 grams of lightyellow sophora root, 6-60 grams of weeping forsythia, 6-60 grams of unprocessed coix seed, 6-60 grams of honeysuckle flower and 6-60 grams of red-rooted salvia root. The preparation method of the wart treating medicament comprises the following steps of: A, preparing a film coating agent 1#; and B, preparing a film coating agent 2#. By applying a No.1 medicinal film once, all warts can be removed, and viruses in a wart at an infection focus are cleared completely at first. By coating a No.2 medicinal film on and around the infection focus (once every day), residual viruses can be cleared completed, and the aim of healing is fulfilled.

The invention discloses a pharmaceutical composition for treating ulcerative colitis, which is prepared from astragalus root and flavescent sophora root as the raw material. the invention also provides the method for preparation and use of the pharmaceutical composition.

The invention relates to a paddy field weeding composition which takes allylene oxadiazon, pretilachlor and oxyfluorfen as active ingredients. The composition can be prepared into an emulsion in water or a film-forming oil solution, and is used for preventing and treating annual grass family and broad leaf weeds in paddy fields.

A dispersing tablet of tamoxifen citrate is prepared from tamoxifen citrate, disintegrant, filler, lubricant and alcohol through sieving by 100 meshes, proportionally mixing, wet granulating, drying, sieving by 18-24 meshes, adding lubricant, and tabletting. It can be used for treating mastadenoma, melanocarcinoma, etc.

The invention discloses a fatigue-relieving traditional Chinese medicine health product, which is composed of the following seven traditional Chinese herbals: ginseng, processed rhizoma polygonati, wolfberry, raspberry, maca, epimedium, and cervus elaphus antler. The pharmacodynamic test result show that the health product can prolong the load swinging time of mice, the contents of hepatic glycogen and lactic dehydrogenase are increased, the contents of serum urea nitrogen and blood lactic acid are reduced, and the health product has a prominent fatigue relieving effect.

An orally taken target medicine for treating the ulcerative colitis with high curative effect and low dosage is prepared from the extract of American periplaneta. Its preparing process is also disclosed.

The invention discloses a Shuanghuanglian effervescence tablet added with a moisture-proof agent or a drying agent and a preparation method of the Shuanghuanglian effervescence tablet, wherein the raw medicine materials of the effervescence tablet comprise Shuanghuanglian extract powder, an effervescence agent, the moisture-proof agent or the drying agent, a flavoring agent and a lubricating agent. The Shuanghuanglian effervescence tablet has the advantages of reasonable proportion of a main medicine and auxiliary materials, good formation and stability, good clarity after disintegration, convenience in use and favorable mouth feel, and the compliance of the Shuanghuanglian effervescence tablet is increased and medicine effect is guaranteed.

The invention relates to Zuojin helicobacter-pylori-resistant floating tablets and a preparation method thereof. The floating tablets are characterized by comprising 0.2 to 0.75 part of Zuojin alkaloid extract, 0.1 to 0.4 part of hydrophilic macromolecular material, 0.1 to 0.4 part of floating auxiliary agent, 0.01 to 0.1 part of foaming agent, 0.04 to 0.1 part of release regulator and a proper amount of starch, wherein the final total amount is 1 part. The preparation method comprises the following steps of: mixing the Zuojin alkaloid extract, 70 to 90 percent of the hydrophilic macromolecular material, the floating auxiliary agent, the foaming agent, the release regulator and the proper amount of starch in part uniformly, sieving the mixture with a sieve of 60 to 100 meshes, preparing a soft material by using water or 2 to 10 percent polyvinyl pyrrolidone ethanol solution or ethanol solution as an adhesive, sieving with a sieve of 10 to 24 meshes to prepare granules, drying the granules in the air at the temperature of 30 to70 DEG C, and mixing the rest hydrophilic macromolecular material, magnesium stearate in an amount accounting for 1 percent of the total amount and the granules, wherein the total amount is 1 part; and tableting the mixture by using a single-punch tablet press, wherein the weight of each tablet is 500mg, and the hardness is controlled between 30N and 60N. The tablets have the characteristics of constant and complete medicament release, reduced administration amount and administration times, and enhanced treatment effect; and the Zuojin helicobacter-pylori-resistant floating tablets for treating Hp infected stomach diseases are prepared with excellent prescription, compact pharmacological basis, reasonable processes and novel formulation, and are favorable for overcoming the defects of western medicaments, digging the treasure of the traditional Chinese medicine and exerting the treatment advantages of the traditional Chinese medicine.

The invention relate to effervescent tablets of haw thorn, process of preparation, method for detection and quality control, wherein the effervescent tablets are the conversion to the dose form of electuary, and are prepared from prescription of haw thorn, medicated leaven and malt through steps of extracting, concentrating, spray drying, charging pharmaceutically acceptable excipient, palletizing and tabletting.

The invention provides double-layer spray essence with the efficacies of preserving moisture, brightening skin and weakening wrinkles and a preparation method of the double-layer spray essence. The double-layer spray essence is prepared from the following components in percentage by weight: 1-25 % of fructus rosae oil, 1-15 % of sodium PCA, 1-10 % of natural moisturizing factors, 0-10 % of rose flower extract, 1-15 % of isododecane, 0-10 % of glycerinum, 0.1-3 % of mung bean seed extract, 0-5 % of calendula oil, 0-2 % of rose essential oil, 0-2 % of tocopheryl acetate, 0.1-2 % of sodium chloride, 0-1 % of rosemary leaf extract, 0.05-1 % of decyl glucoside, 0.1-2 % of a preservative, and the balance of water. The double-layer spray essence can comprehensively supplement and regulate the moisture and nutrition of the skin, effectively enhance the moist and lubrication properties of the skin, and also can effectively eliminate free radicals and resist glycosylation, so that the skin color is bright, the skin is compact, the wrinkles are faded, and then the skin is smooth and elastic, and has the natural luster.

The invention relates to a tadalafil containing orally-dissolved film agent and a preparation method thereof. The tadalafil containing orally-dissolved film agent starts to be absorbed in the oral cavity, takes effect quickly and is good in treatment effect and convenient to take, and water drinking is not needed. The tadalafil containing orally-dissolved film agent comprises the active ingredient tadalafil, a high-polymer film-forming material, a skin penetration enhancer and pharmaceutically-acceptable other auxiliary materials, wherein the weight percentage of tadalafil in the orally-dissolved film agent is 10-50%, preferably 20-50%; the D90 partical size of tadalafil is smaller than or equal to 25 microns, preferably smaller than or equal to 20 microns and more preferably smaller than or equal to 15 microns. The skin penetration enhancer is added into the prescription, meanwhile, the particle size of the bulk pharmaceutical chemical is controlled, tadalafil is micronized, it is ensured that the medicine is partially absorbed at the oral mucosa, the active ingredient is absorbed in the oral cavity more rapidly, and the film agent takes effect faster than tablets and other common film agents.

The invention discloses a preparation method of an enema for chronic renal failure for solving the treatment problem of the chronic renal failure. The preparation method is characterized in that the preparation method comprises the following steps of: (1) performing reduced pressure distillation on ailanthus-like pricklyash bark, catclaw buttercup root and dried mussel coarse powder to extract volatile oil; (2) performing reduced pressure decoction on tall gastrodia tuber to obtain a filtrate; (3) performing water decoction on trikeraia hookeri, magnolia amoena, dragon's blood, melanoidin malt, scorch-fried medicated leaven, mimoselike rosewood leaf, peach gum, cassia twig and dregs obtained in the step (1) to obtain a filtrate for later use; (4) merging the filtrates obtained in the steps (2) and (3), performing reduced pressure concentration to obtain a dry extract, and crushing to obtain dry extract powder; (5) spraying the volatile oil obtained in the step (1) into the dry extract powder obtained in the step (4), uniformly mixing, and screening by a 100-mesh screen to obtain colon dialysis concentrated powder; and (6) adding ten times the volume of warm water into the colon dialysis concentrated powder obtained in the step (5) during the use, and uniformly mixing. Clinical experiments prove that by using the enema for treating the chronic renal failure, the frequency of hemodialysis can be reduced, and the preparation method is further worthy of clinical application and popularization.

The invention discloses a novel process for a Chinese medicinal composition for reducing blood fat and a method for preparing novel formulations. Different formulations are prepared by different extraction methods. Medicinal materials are partially or fully extracted by ethanol in different proportions according to a prescription to prepare hard capsules, soft capsules, tablets and sustained-release preparations respectively. By adopting the modern technology, the novel process and the method improve the technical content of the medicament, ensure that the active ingredients of each medicinal material can be fully extracted, and provide the safe, effective and controlled medicament for reducing the blood fat. The method can provide more choices for wide patient groups through the research of the different formulations, and at the same time, the dosage is reduced; and the Chinese medicinal composition is taken, stored and transported conveniently, and satisfies the patient.

The invention discloses a preparation method of a chronic renal failure colon dialysate for solving the treatment problem of chronic renal failure. The preparation method is characterized in that the preparation method comprises the following steps of: (1) performing reduced pressure distillation on ailanthus-like pricklyash bark, catclaw buttercup root and Chinese ephedra root coarse powder to extract volatile oil; (2) performing reduced pressure decoction on tall gastrodia tuber to obtain a filtrate; (3) performing water decoction on trikeraia hookeri, magnolia amoena, dragon's blood, melanoidin malt, scorch-fried medicated leaven, mimoselike rosewood leaf, peach gum, cassia twig and dregs obtained in the step (1) to obtain a filtrate for later use; (4) merging the filtrates obtained in the steps (2) and (3), performing reduced pressure concentration to obtain a dry extract, and crushing to obtain dry extract powder; (5) spraying the volatile oil obtained in the step (1) into the dry extract powder obtained in the step (4), uniformly mixing, and screening by a 100-mesh screen to obtain colon dialysis concentrated powder; and (6) adding ten times the volume of warm water into the colon dialysis concentrated powder obtained in the step (5) during the use, and uniformly mixing. Clinical experiments prove that by using the chronic renal failure colon dialysate for treating the chronic renal failure, the frequency of hemodialysis can be reduced, and the preparation method is further worthy of clinical application and popularization.

A Chinese medicine in the form of dripping pill for treating enterogastric disease is prepared from calyx-shaped daphniphyllum and salicileaf dockleaved knotweed through extracting in water, mixing with auxiliary, etc.

The invention relates to a kind of medicine that takes plant extract as medical effective component and the method for preparing the same. The comprised components in effervescence and their proportions (by weight)are as follows: pseudo-ginseng flower and leaves and stem extract 10-40%, the left is medical findings; said findings comprises: urinary citric acid 6-20%, sodium acid carbonate 10-30%, macrogol 6000 2-10%, lactose 20-50%, stevia rebaudiava 2-10%, hydroxypropyl starch 5-15%, silicon micronized quartz powder 0.2-1%, and dolomol 0.5-1.5%. The method comprises following steps: disintegrating and screening pseudo-ginseng flower and leaves and stem extract, urinary citric acid, stevia rebaudiava, hydroxypropyl starch, silicon micronized quartz powder with 80 order screen, producing particle with 70-95% ethanol, drying at 60-80 Deg. C, getting particle, adding macrogol 6000 into sodium acid carbonate, stirring evenly, cooling and disintegrating, mixing with said particle and dolomol, sheeting and packing with complex memebrane.

The invention discloses a new preparation of rosiglitazone maleate: rosiglitazone maleate tablets and a process for preparation, which is made of rosiglitazone maleate 1-20%, disintegration agent 1-70%, bulking agent 10-90%, and lubricating agent 0.1-2%. The invention of rosiglitazone maleate tablets have the advantages of novel preparation, convenient intaking, excellent absorbability, less stimulation on the gastrointestinal tract, stable quality for long-term storage, and especially adapt to the old and the patient with deglutition difficulties. The preparation technique is simple and has no particular requirement on equipment, which adapts to large-scale production. The invention can be used to prepare the medicament for the treatment of II-type diabetes mellitus.

The invention belongs to the technical field of pesticides, and relates to a weeding composition. The weeding composition is characterized by comprising three active ingredients of halauxifen-methyl, carfentrazone-ethyl and fluroxypyr. The weeding composition has the advantages that the weeding spectrum is broad, the weeding effect is obvious, the safety of crops is realized, the lasting period is prolonged, and the synergistic function is obvious.

A Chinese medicine in the form of adhesive film for treating coronary heart disease and angine pectoris is prepared through classifying the Chinese-medicinal materials, extracting, refining, concentrating, mixing, adding borneol powder, stirring, mixing with cellulose solution and glycerine, coating, drying, cutting, and attaching it on non-woven fabric.

The invention provides a zinc oil preparation for treating burn and scald and preparation process thereof, wherein the preparation comprises (by weight proportion) schisandra fruit 4-6 parts, rheum officinale 4-6 parts, notoginseng 2-3 parts, licorice root 4-6 parts, zinc oxide 10 parts, dyclonine 1 part, and ground substance 75-68 parts.

The invention discloses a preparation prescription and preparation technology of gel liniment for treating acnes. The preparation prescription comprises 6.0-10.0 g of a film forming agent, 0.5-2.0 g of an excipient, 3.0-8.0 g of a filling agent, 6.0-10.0 g of a humectant / plasticizer, 1.0 g of essence, 10 g of ethyl alcohol, 5.0-10.0 g of medicine and the balance purified water, wherein the total weight of the materials is 100 g. The preparation technology includes the steps that the film forming agent, the excipient and the filling agent are added into a proper amount of purified water, heated, dissolved and evenly stirred to obtain a blank matrix; the essence is dissolved in ethyl alcohol, and the humectant / plasticizer and the medicine are added and stirred evenly or ground evenly; part of the medicine is added into the blank matrix, uniformly mixed and subpackaged to obtain the gel liniment. Clinical and pharmacological experiments prove that the gel liniment has the effects of clearing away lung-heat and toxic materials, resolving dampness and relieving swelling and removing stasis, and is mainly used for treating acnes caused by lung channel blood heat and damp-heat stagnation.The method is easy to operate, and industrial production is easy to achieve.

The invention discloses a refined puncturevine fruit saponin capable of being administered by injection and its preparing process which comprises, extracting puncturevine saponins through thanol backflow, cooling down, filtrating, charging in alcoholic solution of phytosterin or cholesterol, backflow reacting, decompressing for reclaiming ethanol, watering, freezing, filtrating, charging activated charcoal into the filtrate, stirring, filtering, decompression concentrating the filtrate, charging acetone while stirring, airtight stewing, removing the dissolvent, decompressing, drying and disintegrating.

The present invention is a kind of Chinese medicine composition for treating gynecological diseases and its preparation process and application. The Chinese medicine composition is prepared with oroxylum seed, wild chrysanthemum flower, red peony root, borneol and calm powder. The Chinese medicine composition may be effervescent tablet, effervescent capsule, effervescent granule, lution, supporsitory, gel or other pharmaceutically acceptable preparation forms.

The invention discloses a vegetable meat meal replacement bar with satiety and meal replacement effects. The vegetable meat meal replacement bar comprises the following raw materials: purified water,a vegetable tissue protein, vegetable protein powder, konjaku flour, carrageenan, carboxymethyl cellulose, chitosan oligosaccharide, mulberry leaf powder, salt and mixed spices. The invention furtherdiscloses a preparation method which comprises: firstly, soaking the dried vegetable tissue protein with water until the dried vegetable tissue protein is soft, and then carrying out filamentization processing; then uniformly mixing the raw material obtained after filamentization processing, adding the purified water, the plant protein powder, the konjaku flour, the carrageenan, the carboxymethylcellulose, the chitosan oligosaccharide, the mulberry leaf powder, the salt and the mixed spices to carry out mixing stirring processing; and finally, carrying out film pressing, bagging, vacuumizingand sealing on the materials after mixing stirring processing, and finally, carrying out sterilization processing. The vegetable meat meal replacement bar with the satiety and meal replacement effects, which is disclosed by the invention, is balanced in nutrition, has an obvious effect in the aspect of satiety, has a meat flavor and taste, and meets demands of people for meat foods.

The invention provides microcapsule spray essence with an effect of regulating balance of moisture and oil and a preparation method thereof. The microcapsule spray essence is prepared from dipropylene glycol, microcapsules, polyethylene glycol-8, glycine betaine, trehalose, tara gum, fomes officinalis ames extract, mung bean seed extract, herbal selaginellae extract, malachite extract, 1,2-hexalene glycol, hydroxyacetophenone, natural moisturizing factor, freshener, arginine, carbomer and the balance of water. The microcapsule spray essence is rich in moisturizing factors and plant essence, can be used for comprehensively supplying and regulating moisture and nutrition for skin from skin bottom, can durably keep skin moisturized, and enables skin to achieve the optimized state since the plant essence and microcapsule oil beads can be used for effectively regulating balance of moisture and oil of skin.

The invention discloses a hair styling composition, which is prepared from the following raw materials in percentage by weight: 10 to 50 percent of fatty alcohol-polyoxyethylene ether, 10 to 40 percent of styling agents, 1 to 20 percent of polyethyleneglycol modified acylglycerol, 1 to 20 percent of polyethenoxy ether modified castor oil, 1 to 20 percent of modified wax, 10 to 50 percent of conditioning and moisturizing agents and deionized water for supplementing to 100 percent. The hair styling composition has the advantages that the hair glossiness can be obviously improved; the hair fixing composition is also suitable for repeated styling of hair.

The invention discloses azithromycin eye drops. The azithromycin eye drops are a stable eye preparation which is prepared from azithromycin serving as a main active ingredient and proper auxiliary materials. The long-acting eye drops with mucosa adhesiveness prepared from the latest auxiliary materials at home and abroad have a medicine controlled-release system, the active ingredient stops in eyes for several hours to enhance the antibacterial activity of target tissues, so that the using frequency of the eye drops can be reduced, and the eye drops are convenient to use. The azithromycin eye drops are suitable for treating bacterial conjunctivitis caused by microbial sensitive strains such as G group corynebacterium, haemophilus influenzae, staphylococcus aureus, streptococcus mitis groups and streptococcus pneumoniae.

The invention provides a low-rust-flavor calcium-iron-zinc chewable tablet. The chewable tablet comprises main raw materials, main auxiliary materials, an acidity regulator, a sweetening agent and a flavoring agent. The main raw materials comprise calcium carbonate, ferrous gluconate and zinc oxide; the main auxiliary materials comprise the following components: sorbitol and white granulated sugar; the components are combined according to the following percentage: 30%-40% of calcium carbonate, 1%-2% of ferrous gluconate, 0.1%-0.2% of zinc oxide, 30%-40% of sorbitol, 20%-30% of white granulatedsugar, 0.2%-1% of an acidity regulator, 0.1%-0.5% of a sweetening agent, and 0.1%-0.5% of corrigent. The chewable tablet is a novel product, has a sour taste and tasty and has no rust flavor. Meanwhile, the invention provides a preparation method of the low-rust-flavor calcium-iron-zinc chewable tablet, the chewable tablet is prepared by adopting the steps of mixing, granulating, drying and tabletting, the process is reasonable, the stable specification of the product can be ensured, and the chewing effect is good.

The invention relates to a traditional Chinese medicine, that is a soft capsule of Chinese thorowax and baicalin extractive, and a method of quality control thereof. The traditional Chinese medicine consists of the following ingredients according to the weight content: 1,250 grams of Chinese thorowax, 90 grams of baicalin extractive (in terms of baicalin), 40 grams of propanediol and 300 to 500 grams of carmowax 400. The method of quality control consists of qualitative authentication and content measurement. The soft capsule of Chinese thorowax and baicalin extractive has the characteristics that the taking is convenient, the bioavailability is high and no restriction is exerted to the capsule user. A diluting agent is preferably selected to make the capsule neither too hard nor too soft and make the quality stable. Simultaneously, the Chinese thorowax in the formula is conducted an aqueous extraction and ethanol sediment and baicalin is charged as an extractive, which is fit to be made into a soft capsule with a novel preparation formulation and improved curative effect. The method of quality control can control the active ingredients of the soft capsule of Chinese thorowax and baicalin extractive effectively; moreover, the method is stable and reliable and has strong specificity, thereby enhancing the overall quality of the soft capsule of Chinese thorowax and baicalin extractive greatly and guaranteeing the curative effect.