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62results about How to "Increase structural diversity" patented technology
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Protein structure prediction system
ActiveUS20180260517A1Increase structural diversityImprove discovery rateChaos modelsNon-linear system modelsEnergy minimizationTarget peptide
The present invention is an accelerated conformational sampling method for predicting target peptide and protein structures comprising a process of determining energy minimized synthetic templates using a simple system for modeling individual molecular bonds within the subject peptide or protein. Use of these synthetic templates greatly reduces the computational resources necessary for optimally determining structural features of the target peptide or protein. The present invention also provides methods for rapid and efficient analysis of the effect of mutations on target peptides and proteins.
Owner:DNASTAR
Method for marking and modifying biomacromolecules by one-pot process
ActiveCN105111265ASimple process routeMild reaction conditionsSugar derivativesSugar derivatives preparationSolventBiological macromolecule
The invention discloses a preparation method of biomacromolecules modified by linking chemical molecules disclosed as Formula I or Formula II by a one-pot process, which comprises the following steps: dissolving compounds disclosed as Formula A or Formula B in a solvent, and directly reacting in the presence of an alkali and a ligand by using an azide transfer reagent and a copper catalyst in a buffer solution with the pH value of 4.0-11.0 to generate the compounds disclosed as Formula I or Formula II, wherein R1 and R2 are respectively and independently selected from biomacromolecules or chemical micromolecules, and biomacromolecules or chemical small molecules when being different. The novel method for chemically modifying biomacromolecules has the advantages of simple process route and mild reaction conditions. By adopting imidazolyl sulfonyl azide hydrochloride or trimethyl silyl azide as the azide transfer reagent, the method has high operational safety, does not need to separate or purify the intermediate product, saves the procedures, lowers the operation difficulty, can be used for preparing biomacromolecules with different chemical modifications, and is very suitable for industrial application.
Owner:HITGEN INC
Application of flexible magnetic material for producing magnetic core of printed circuit board transformer
InactiveCN101299378ALow costReduce the number of layersTransformers/inductances magnetic coresInductances/transformers/magnets manufactureMagnetic tapeTransformer
The invention discloses a PCB transformer made of the flexible magnetism materials and the device of the novel PCB transformer, characterized in that: (1) the flexible magnetic conductive material with higher magnetic permeability is adopted to compose the magnetic core of the PCB transformer, wherein the magnetic core materials can be the electrician pure iron, the doped improved magnetism materials or other novel magnetic conductive materials; (2) the magnetic core structure can adopt the multi-corelong magnetic wire structure; (3) the magnetic core structure can adopt the braid over braid structure; (4) the magnetic core structure also can adopt the thin laminarization flexible magnetic tape structure; (5) the magnetic core and the coil of the PCB transformer adopt the matrix structure. The flexible magnetic conductive material materials and the PCB transformer design are combined, meanwhile the magnetic core of the PCB transformer and the coil adopt the matrix design project, to reduce the volume of the transformer, reduce the cost of the transformer and the number of the PCB ply.
Owner:XI AN JIAOTONG UNIV
Amino-protected 3-hydroxy adamantane glycine benzothiazole-2-thiol active ester as well as preparation method and application thereof
ActiveCN106349185AIncrease structural diversityCheap and easy to getOrganic chemistryChemical recyclingSaxagliptinChemical structure
The invention relates to an amino-protected 3-hydroxy adamantane glycine benzothiazole-2-thiol active ester as well as a preparation method and application thereof. The thiol active ester is prepared by virtue of reaction between amino-protected 3-hydroxy adamantane glycine and dibenzothiazyl disulfide. The invention further discloses application of the compound in the preparation of a saxagliptin intermediate and saxagliptin. The invention provides a brand new chemical structure. The preparation method is simple and low in cost; the compound is applicable to the preparation of saxagliptin, so that the preparation process can be effectively simplified; and the reaction is mild, and the compound has a wide generalization prospect.
Owner:艾博仕医药科技石家庄有限公司
Assembly type prefabricated structure wallboard unit and connecting joints thereof
InactiveCN106400952AImprove safety and reliability performanceImprove compactnessWallsRebarWall plate
The invention discloses an assembly type prefabricated structure wallboard unit and connecting joints thereof. The assembly type prefabricated structure wallboard unit is a prefabricated component which is provided with two surfaces and four junction faces and mainly made of concrete. The assembly type prefabricated structure wallboard unit comprises reserved connecting rebars exposed out of the four junction faces. The exposed parts of the reserved connecting rebars on the two vertical junction faces are in a [ shape or an L shape and form the vertical junction face reserved rebars. The reserved connecting rebars comprise the edge component reserved connecting rebars and non-edge component reserved connecting rebars between the junction face at the upper end and the junction face at the lower end, and exposed parts of the rebars form the upper and lower end reserved rebars. The connecting joints comprise the vertical seam connecting joint and the horizontal seam connecting joint. The wallboard unit and the connecting joints have the advantages that site construction is convenient, safety and reliability are achieved, and the wallboard unit and the connecting joints have the same performance of a cast-in-place structure, and the structure design principle that the bearing force of the joints is higher than that of the components is achieved.
Owner:刘祥锦
Dihedral angle information auxiliary energy function selection based protein structure prediction method
ActiveCN109448784AReduce the impactEnhance local structureInstrumentsMolecular structuresNative structureEnergy functional
The invention discloses a dihedral angle information auxiliary energy function selection based protein structure prediction method. extracting dihedral angle information according to a Ramachandran plot corresponding to a protein residue; performing assessment on conformation by using the energy functions and the dihedral angle information in a Rosetta algorithm; giving different weights to two fractions, designing a new scoring function, and performing selection on the fragment assembled conformation by using the scoring function so that the influence on the three-dimensional structures of proteins due to inexact energy functions can be reduced; and performing global search and local search on the conformation, and performing enhancement on local structures on the basis of guaranteeing the global topological structure of the constellation so that more near-native structures can be obtained. Thus, the dihedral angle information auxiliary energy function selection based protein structure prediction method with good sampling capabilities and high prediction precision can be provided.
Owner:深圳新锐基因科技有限公司
Lysinibacillus fusiformis and application thereof in land reclamation and ecological reconstruction in mining area
ActiveCN108893421AIncrease biomassIncrease diversityBacteriaMicroorganism based processesCommunity structurePotassium
The invention discloses lysinibacillus fusiformis and an application thereof in land reclamation and ecological reconstruction in a mining area. The strain is the lysinibacillus fusiformis, and has acollection number of CGMCC No. 9799. The strain is capable of improving the nutrient content of land reclamation soil in the mining area, and has obvious effects for improving the content of organic matters, alkali-hydrolyzale nitrogen, rapidly available potassium and available phosphorus in the land reclamation soil in the mining area. Moreover, further experiments prove that, the lysinibacillusfusiformis is capable of further improving the biomass of crops, and for culture of wheat or oilseed rapes, the biomass of crops in the land reclamation soil in the mining area can be improved; particularly important, due to use of the lysinibacillus fusiformis, the community structure of soil microorganisms can be effectively and obviously changed, the microbial diversity of the soil is improved,and the quantity of microbes is effectively increased. Therefore, remediation of the microbial community in the soil is accelerated, and the lysinibacillus fusiformis can be widely applied to remediation of the land reclamation soil in the mining area.
Owner:SHANXI UNIV +1
Preparation method of static loaded multi-coating yarn or fabric material
The invention discloses a preparation method of a static loaded multi-coating yarn or fabric material. The preparation method is characterized by including the following steps that 1), a yarn or fabric substrate material is put in a dopamine treatment bath to be treated, the material is washed and dried after being treated, and the yarn or fabric substrate material with a poly-dopamine binding layer is obtained; 2), the yarn or fabric substrate material with the poly-dopamine binding layer is put in a silver ammonia solution, a reducing agent solution is dropwise added into the silver ammoniasolution to be treated, the material is washed and dried after being treated, and the yarn or fabric substrate material with the binding layer and an electric conductance layer is obtained; 3), the yarn or fabric substrate material with the binding layer and the electric conductance layer is treated in a power storage polymer solution, then the redundant solution is removed through a roller, the material is dried, and the yarn or fabric substrate material with the binding layer, the electric conductance layer and a power storage layer is obtained. On the basis of the basic decorating and beautifying functions of textiles, the additional functions of the textiles are further improved, and functionalization development of the textiles can be promoted.
Owner:DONGHUA UNIV
Ketene triazole compound and synthesis method thereof
InactiveCN104262270AIncrease structural diversityEasy to operateOrganic chemistryFuranSynthesis methods
The invention discloses a ketene triazole compound and a synthesis method thereof. The structural formula of the compound is disclosed in the specification. Alkyl or aryl azide and various substituted 2-furancarbinol used as initial raw materials are subjected to Lewis-acid-promoted [3+2]-cycloaddition / furan ring opening cascade reaction to generate a (E)-configuration 1,2,3-triazole and ketene / aldehyde conjugated skeleton structure. The method is simple to operate, the reagent is the low-cost Lewis acid, and the substrate has wide application range; and thus, the method can be used for synthesizing a series of high-functional-group substituted complex ketene triazoles, and has the advantages of high economical efficiency of steps, diversified product structures and stereospecificity of (E)-configuration.
Owner:SHAANXI NORMAL UNIV
Roadbed detecting device for roads
InactiveCN107152017AOptimize detection programGuaranteed detection accuracyIn situ soil foundationEngineeringInfrared emitter
The invention provides a roadbed detecting device for roads. The device comprises a main chassis; a computer display screen is fixed on the main chassis; a first rail is fixed on the left side of the main chassis; a first CCD sensor is slidingly mounted on the first rail; a second rail is fixed on the right side of the main chassis; a second CCD sensor is slidingly mounted on the second rail; the top end of the main chassis is connected with a rail module of an infrared emitter through a support rod; the rail module comprises a third rail and a fourth rail; a first infrared emitter is slidingly mounted on the third rail; a second infrared emitter is slidingly mounted on the fourth rail; signals emitted by the two infrared emitters can be received through a signal receiver and sent to the two CCD sensors; and the signal receiver is rotationally mounted on a fixed column. Compared with traditional roadbed detecting equipment, the device is more precise in detection, high in practicability and suitable for popularization and application.
Owner:西藏灵芝草建设咨询集团有限公司
Resonance transformer structure
ActiveCN102054572AVolume thinningIncrease the output voltageTransformers/inductances coils/windings/connectionsTransformers/inductances magnetic coresManufacturing cost reductionResonance
The invention provides a resonance transformer structure, which comprises a first winding base, a primary winding, a plurality of secondary windings and a magnetic core group, wherein the first winding base comprises a body and a channel, wherein the channel passes through the body; and the body is provided with a first winding zone and a plurality of second winding zones of single grooves; the first winding zone is provided with a plurality of lead pins; the plurality of second winding zones of the single grooves are arranged at the two sides of the first winding zone; the primary winding iswound on the first winding zone of the first winding base, and is connected with the plurality of lead pins; the plurality of secondary windings are respectively wound on the plurality of second winding zones of the single grooves on the first winding base; and a part of the magnetic core group is arranged in the channel of the first winding base. The resonance transformer structure can enhance current transfer power, and reach the purpose of stably controlling a leakage inductance value; and meanwhile, the volume of the resonance transformer is thinned. In addition, the output voltage of theresonance transformer can be increased, thus being high in structure diversity, reducing manufacturing cost, and the like.
Owner:DELTA ELECTRONICS INC
Alkenyl amide triazole compound and synthetic method thereof
InactiveCN105272928AIncrease structural diversityEasy to operateOrganic chemistryAntineoplastic agentsFuranCycloaddition
The invention discloses an alkenyl amide triazole compound and a synthetic method thereof. The compound has the following structural formula (see the formula in the description). According to the synthetic method, alkyl or aryl azide, various kinds of amine and various substituted 5-halogeno-2-furfuryl alcohol compounds are used as starting raw materials, and a 1,2,3-triazole and alkenyl amide conjugated skeleton structure of (Z)-configuration is generated through a [3+2]-cycloaddition, furan ring opening and amidating series reaction accelerated by lewis acid. The synthetic method is easy to operate, the used reagent is the low-cost lewis acid, the substrate is wide in application range and capable of being used for synthesizing a series of complex alkenyl amide triazole compounds substituted by functional groups highly, and step economy, product structural diversity and (Z)-configuration stereospecificity are high.
Owner:SHAANXI NORMAL UNIV
Method for producing compound fungus feed and edible mushrooms at the same time
ActiveCN104718990AImprove the comprehensive and efficient rate of resourcesSave foodFood processingAnimal feeding stuffCelluloseBearded tooth
The invention discloses a method for producing compound fungus feed and edible mushrooms at the same time. The method mainly comprises the steps that, several animal feed common raw materials comprising corn, wheat, rice, wheat bran and cake type protein are evenly mixed with one or more of agricultural product leftover crude cellulose raw materials, and the fixture is used as the culture media of the edible mushrooms including ganoderma fungus, hericium erinaceus fungus, agrocybe cylindracea fungus and pleurotus eryngii fungus; after the mushrooms grow out, each culture medium existing after the fungus grow out are evenly mixed with cordyceps fungus culture medium produced with a conventional method according to a ratio, after each mixture is smashed roughly, each mixture, the cake type protein and corn flour are fine smashed, and then the compound fungus feed is generated. By the adoption of the method, the problem that hormones and antibiotics are added to feed in the feed industry for a long time, hormones and antibiotics residuals exist in animal end products, and then after people eat the animal end products, the hormones and antibiotics residuals do harm to the health of people is solved, the pollution to the environment in the process of producing the agricultural product leftovers is reduced, the waste is recycled, and the purposes of resource recycling and efficient utilization are achieved.
Owner:宾石其
Method for improving methane gas yield of anaerobic digestion of sludge and reducing ecological toxicity of heavy metals
ActiveCN112142284AIncrease gas productionImprove adsorption capacityWater contaminantsWaste based fuelNanoparticleManganese oxide
The invention discloses a method for improving methane gas production rate of anaerobic digestion of sludge and reducing ecological toxicity of heavy metals, and belongs to the technical field of environmental protection. The method comprises the following steps: carrying out high-temperature pyrolysis on straws serving as a raw material under an anaerobic condition to obtain straw biochar, and carrying out chemical modification on the straw biochar under an alkaline condition to obtain an iron-manganese oxide nanoparticle loaded biochar material; adding the iron-manganese oxide nanoparticle loaded biochar material into an anaerobic digestion device according to a certain proportion, and carrying out anaerobic fermentation, so that the stability of the anaerobic digestion process can be greatly enhanced, the methane gas production rate can be increased, the ecological toxicity of heavy metals can be reduced, and the adsorption capacity to heavy metal ions can be improved.
Owner:TONGJI UNIV
Bacillus cereus and application thereof to improve plant drought-resistant capability
ActiveCN103667132BImprove drought resistanceIncreased drought capacityBacteriaMicroorganism based processesBacteroidesCommunity structure
The invention discloses a strain of bacillus cereus which is preserved in China General Microbiology Center of Committee for Culture Collection of Microorganisms since 31st December, 2014, and the preservation number is CGMCC No. 7069. The bacillus cereus L90 provided by the invention is capable of improving the drought resistant capability of juglans regia. Experiment research shows that after the bacillus cereus provided by the invention is inoculated to the surround of juglans regia roots and juglans regia is stressed by drought for a certain time, juglans regia is substantially improved in bacterial community structure diversity in rhizosphere soil compared with juglans regia inoculated with common growth-promoting bacteria, the leaf relative water content and the water utilization efficiency are improved, and the drought resistance of the plant is enhanced. Therefore, the bacillus cereus provided by the invention or a bacterium preparation by taking bacillus cereus as a raw material can be used as an inoculation agent and applied to drought environment, and the bacillus cereus provided by the invention helps to provides an excellent bacterial strain resource for improving the drought resistance of juglans regia.
Owner:SHANDONG FOREST SCI RES INST
Horizontal joint connecting node of assembled prefabricated structure wallboard unit
InactiveCN110761398AImprove safety and reliability performanceImprove compactnessWallsFloor slabArchitectural engineering
Owner:刘祥锦
Reinforced guide plate production process
InactiveCN111469442AHigh strengthReduce weightDomestic articlesUltimate tensile strengthBoard structure
The invention relates to the technical field of rail transit equipment production, in particular to a reinforced guide plate production process. The reinforced guide plate production process comprisesthe steps of: processing a composite material reinforcing rib structure; designing a concave area on a guide plate body, and determining a first position where the concave area is formed on each prepreg laying layer where the guide plate body is formed; cutting the prepreg laying layer at the first position to form a hole; blocking the hole through an additional position supplementing structure,and arranging a needed concave area on the position supplementing structure; laying the reinforcing rib structure on the prepreg laying layer located on the topmost layer; and integrally forming all the laid prepreg laying layers, the position supplementing structures and the placed reinforcing rib structures through an autoclave technology. According to the production process, the strength of a guide plate is enhanced by changing the structural form of the guide plate, and the guide plate has better practical performance through a corresponding process.
Owner:NEWTRY COMPOSITE
Implanting jawbone with dental implanting sites and digital processing method thereof
ActiveCN110353836AIncrease structural diversityImproved chewing functionDental implantsBone implantDesign softwareImplant prosthesis
The invention relates to the 3D printing method and the precise cutting technology, and discloses a digital processing method of an implanting jawbone. For an existing mainstream jawbone defect restoring method, the jawbone defect is restored, and meanwhile the method has the effect of directly improving the restoration of the chewing function of a patient; due to the implanting sites reserved onthe implanting jawbone, the implanting jawbone can be directly matched with implanting prosthesis, there is no need to restore the chewing function through a local false tooth treatment means after ajawbone operation, the treatment cycle is shortened, the troubles caused when the long-term oral cavity occlusion function is lost in the treatment course in the second time or multiple times of treatment of the patient are omitted, and the influences and operation risk on the rehabilitation of the newly-formed implanting jawbone are reduced; meanwhile, the implanting jawbone obtained through themethod can greatly improve the matching precision between the individualized jawbone and original left jawbone tissue, and the implanting jawbone can better meet the requirements in details; through design software, the jawbone structure diversity, mainly the internal forming structure diversity, is enhanced.
Owner:OPTIMAL MATERIAL TECH CO LTD
Self-assembly modular robot unit, robot and assembly and control method
PendingCN112873188AIncrease structural diversityFlexible assembly methodsProgramme-controlled manipulatorJointsButt jointSelf assemble
The invention relates to a self-assembly modular robot unit, a robot and an assembly and control method. Self-assembly can be achieved through the provided self-assembly modular robot unit, butt joint with other robots and objects can be automatically completed through sensing and control, a combined body formed after butt joint has the overall movement capacity and the joint movement and operation capacity, and the composite movement characteristic from a wheel type / crawler belt to a joint type is achieved. Therefore, the characteristic that group robots are not connected or are weak in connection can be overcome, cross-mode movement is achieved, the structural diversity of the combined robot is improved, the robot forms such as snakelike robot forms and multi-legged robot forms are constructed, the assembling modes are flexible and diversified, and single robots can complete tasks such as obstacle crossing and carrying beyond the self-ability through combination.
Owner:BEIJING UNIV OF POSTS & TELECOMM +1
Enamide triazole compound and its synthesis method
InactiveCN105272928BIncrease structural diversityEasy to operateOrganic chemistryAntineoplastic agentsFuranSynthesis methods
The invention discloses an alkenyl amide triazole compound and a synthetic method thereof. The compound has the following structural formula (see the formula in the description). According to the synthetic method, alkyl or aryl azide, various kinds of amine and various substituted 5-halogeno-2-furfuryl alcohol compounds are used as starting raw materials, and a 1,2,3-triazole and alkenyl amide conjugated skeleton structure of (Z)-configuration is generated through a [3+2]-cycloaddition, furan ring opening and amidating series reaction accelerated by lewis acid. The synthetic method is easy to operate, the used reagent is the low-cost lewis acid, the substrate is wide in application range and capable of being used for synthesizing a series of complex alkenyl amide triazole compounds substituted by functional groups highly, and step economy, product structural diversity and (Z)-configuration stereospecificity are high.
Owner:SHAANXI NORMAL UNIV
Preparation method and application of multi-target inhibitor acting on QC and GSK-3beta
ActiveCN110950869AIncrease structural diversityOrganic active ingredientsNervous disorderPharmacophorePharmaceutical drug
The invention discloses a preparation method and application of a multi-target inhibitor acting on QC and GSK-3 beta. The structural general formula of the multi-target inhibitor prepared by the method is shown in the specification. According to the invention, according to active center crystal structures of target QC and GSK-3 beta zymoprotein, multiple high-activity pharmacophores are integrated, the multi-target inhibitor capable of acting on QC and GSK-3 beta at the same time is prepared through framework transition and recombination design, the multi-target inhibitor is molecules with multiple target points and high activity, the molecular structure diversity of a lead drug is remarkably expanded, and the research and development of innovative anti-AD drugs and AD diagnostic kits areactively promoted, and the preparation method of the multi-target inhibitor provided by the invention is simple and easy to operate.
Owner:SHENZHEN UNIV
Preparation method of phenyl dithiourea compound
PendingCN114644582AIncrease structural diversityGood application effectOrganic chemistryOrganic solventIodide
The invention belongs to the technical field of COF monomer synthesis, and discloses a preparation method of a phenyl dithiourea compound. The preparation method comprises the following steps: uniformly mixing a phenylenediamine compound, an organic phosphine compound and iodide in an organic solvent, slowly adding trifluoromethanesulfonyl chloride at 0 DEG C under the protection of nitrogen, and reacting at room temperature for 1-4 hours; cooling to 0 DEG C, slowly adding ammonia water, stirring for 5-30 minutes, heating to 50 DEG C, and continuously reacting for 0.5-2 hours; and carrying out centrifugal separation, washing and purifying with an organic solvent for treatment, and carrying out vacuum drying to obtain the phenyl dithiourea compound. According to the preparation method of the phenyl dithiourea compound, one-pot reaction preparation is adopted, the process is mild and easy to control, the purity and yield of the product are high, the substrate universality is high, aftertreatment is simple and rapid, and the product can be prepared on an amplification scale. Due to the advantages, the preparation cost of the phenyl dithiourea compound is remarkably reduced, and the phenyl dithiourea compound has good industrial application value.
Owner:ZHONGYUAN ENGINEERING COLLEGE
Multicyclic peptides and methods for their preparation
ActiveUS11192918B2Increase structural diversityOvercome disadvantagesCompound screeningApoptosis detectionCyclic peptideOrganic chemistry
Owner:THE UNIV OF AMSTERDAM +1
Combinable electrostatic kinetic energy collector and preparation method thereof
ActiveCN111555659AFlexible size adjustmentMake full use of the installation spacePiezoelectric/electrostriction/magnetostriction machinesPolymer scienceThin membrane
The invention relates to a combinable electrostatic kinetic energy collector and a preparation method thereof. The kinetic energy collector comprises a panel, a half-moon-shaped supporting component,an electret film and a groove which are sequentially arranged from top to bottom, if the electret film is formed by covering the upper surface of a polymer film with an upper electrode, negative charges are injected into the lower surface of the polymer film, and the inner surface of the groove is covered with a lower electrode; and if the electret film is formed by covering a lower electrode withthe lower surface of a polymer film, negative charges are injected into the upper surface of the polymer film, and an upper electrode is arranged between the upper surface of the polymer film and thepanel. The panel is connected with the upper electrode through an elastic connecting component, the upper electrode and the lower electrode are respectively connected with an upper electrode lead anda lower electrode lead, and a plurality of kinetic energy collectors are turned over up and down and then are stacked and tiled left and right, so that the gapless combined kinetic energy collector can be obtained. Compared with the prior art, the combinable electrostatic kinetic energy collector can flexibly adapt to different occasions, the installation space is fully utilized, and the kineticenergy collection efficiency is improved.
Owner:TONGJI UNIV
Method for producing 2,5-substituted tetrahydropyran derivatives by reductive elimination of the corresponding 4-halogen derivative
The invention relates to a method for producing the tetrahydropyran derivatives of formula (I), characterized by subjecting a tetrahydropyran derivative of formula (II) to a reductive elimination of substituent X<1>, wherein X<1> represents chlorine, bromine or iodine. The remaining substituents are defined in the claims.
Owner:MERCK PATENT GMBH
Rigid functional ligand-cyclometalated bridge-functional ligand type iridium complex framework
ActiveCN110627838AIncrease structural diversityIncrease property control spaceIndium organic compoundsIridiumComputational chemistry
The invention discloses a rigid functional ligand-cyclometalated bridge-functional ligand type iridium complex framework. According to the rigid functional ligand-cyclometalated bridge-functional ligand type iridium complex framework, a complex contains a bridge ligand capable of being functionally modified, and the complex can be coordinated with two iridium metal centers at the same time; meanwhile, each iridium metal center can be coordinated with other two peripheral functional ligands to form a rigid molecular framework with two metal centers and five ligands; at most three different bidentate ligands exist in a traditional organic iridium complex, that is to say, three modification points are provided; at most five different bidentate ligands exist in the novel molecular framework provided by the invention, so that the number of modification points reaches five, the structural diversity and the property regulation space of the organic metal iridium complex are remarkably increased, and the organic metal iridium complex has potential application value in the important fields of development of high-performance luminescent materials, catalytic systems, solar conversion systems,chemical and biological detection and the like.
Owner:XI AN JIAOTONG UNIV
Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance
PendingCN113546043AHigh interface coverageIncrease structural diversityPharmaceutical non-active ingredientsEmulsion deliveryPickering emulsionOil phase
The invention provides a Pickering emulsion. The Pickering emulsion comprises an oil phase and a water phase, wherein the volume ratio of the oil phase is 4.2%-90%, Alg-beta-CD is dispersed in the water phase, and AzoC12 is dispersed in the oil phase. The invention further provides a super-amphiphilic host-guest alginate-based anisotropic structure soft substance prepared from the Pickering emulsion. A novel amphiphilic-controllable super-amphiphilic Alg-beta-CD / AzoC12 self-assembly is designed and prepared, has better interface adsorption performance and can be used for preparing a W / O / W emulsion with good stability by a phase inversion method. The amphipathy of the super-amphiphilic aggregate can be properly adjusted on the basis of host-guest action, an ideal and convenient strategy can be provided for phase separation behavior control of the host-guest multiphase emulsion, so that the structural diversity of the soft material is realized, and the Pickering emulsion has potential application value in colloidal materials.
Owner:HAINAN UNIVERSITY
Electronic device
ActiveCN111312081AIncrease structural diversityThe size is easy to controlIdentification meansControl electronicsEngineering
The invention provides an electronic device. The electronic device specifically comprises a flexible screen, a shell and a movable insertion part, wherein the shell comprises a front shell and a rearshell which are clamped to form a first accommodating space, part of the flexible screen is arranged on one side, deviating from the rear shell, of the front shell, and part of the flexible screen isarranged in the first accommodating space. A second containing space is formed in the front shell, the movable inserting part comprises a supporting part at least partially arranged in the second containing space and a rolling shaft arranged at the end, away from the second containing space, of the supporting part, and the movable inserting part can move in the opening and closing direction of theflexible screen so that the electronic equipment can be opened and closed; when the electronic equipment is in a closed state, part of the flexible screen is further arranged on the rolling shaft, and when the electronic equipment is in an unfolded state, part of the flexible screen is further arranged on the rolling shaft and the supporting part. Through cooperation of the flexible screen, the shell and the movable insertion part, the electronic equipment in a new form is provided, the size of the electronic equipment can be controlled under the condition that the thickness of the electronicequipment is not increased, and the structural diversity of the electronic equipment is improved.
Owner:GUANGDONG OPPO MOBILE TELECOMM CORP LTD
Method for preparing carbonic ester-carbamate mixed ester based on cellulose carbonic ester
InactiveCN108840986AIncrease structural diversityRealize high-value utilizationBulk chemical productionCelluloseCarbamate
The invention discloses a method for preparing carbonic ester-carbamate mixed ester based on cellulose carbonic ester. The method comprises the following steps: 1) by taking cellulose carbonic ester as a raw material; 2) dissolving the cellulose carbonic ester of the step 1) into a solvent at 10-120 DEG C so as to obtain a product A; 3) putting isocyanate and a catalyst into the product A, and carrying out a reaction for 0.1-10 hours at 20-100 DEG C so as to obtain a product B; 4) putting an anti-solvent into the product B, filtering a precipitate substance, washing and purifying precipitate,and drying, thereby obtaining a cellulose carbonic ester-carbamate mixed ester material. The cellulose carbonic ester-carbamate mixed ester material prepared by using the method is of a novel structure, has the specificity of properties of carbonic ester groups and carbamate groups, has instruction significances in achieving structural diversity and high-value utilization of cellulose and in addition is simple in preparation method and convenient to operate, and the solvent can be recycled.
Owner:GUIZHOU UNIV
A "one-pot" method for labeling and modifying biomacromolecules
ActiveCN105111265BSimple process routeMild reaction conditionsSugar derivativesSugar derivatives preparationSolventBiological macromolecule
The invention discloses a preparation method of biomacromolecules modified by linking chemical molecules disclosed as Formula I or Formula II by a one-pot process, which comprises the following steps: dissolving compounds disclosed as Formula A or Formula B in a solvent, and directly reacting in the presence of an alkali and a ligand by using an azide transfer reagent and a copper catalyst in a buffer solution with the pH value of 4.0-11.0 to generate the compounds disclosed as Formula I or Formula II, wherein R1 and R2 are respectively and independently selected from biomacromolecules or chemical micromolecules, and biomacromolecules or chemical small molecules when being different. The novel method for chemically modifying biomacromolecules has the advantages of simple process route and mild reaction conditions. By adopting imidazolyl sulfonyl azide hydrochloride or trimethyl silyl azide as the azide transfer reagent, the method has high operational safety, does not need to separate or purify the intermediate product, saves the procedures, lowers the operation difficulty, can be used for preparing biomacromolecules with different chemical modifications, and is very suitable for industrial application.
Owner:HITGEN INC
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