Method for preparing super-amphiphilic host-guest alginate-based anisotropic structure soft substance
A soft matter, volume ratio technology, applied in pharmaceutical formulations, medical preparations with inactive ingredients, emulsion delivery, etc., can solve the problem that the interface behavior of super-amphiphilic host-guest polymers has not been further studied, and achieve the realization of The effect of structural diversity and efficient interface stabilization
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[0033] Referring to the accompanying drawings, the present invention will be further described in conjunction with specific embodiments, so as to better understand the present invention. If no specific technique or condition is indicated in the examples, it shall be carried out according to the technique or condition described in the literature in this field or according to the product specification. The reagents or instruments used were not indicated by the manufacturer, and they were all commercially available conventional products.
[0034] 1. Synthesis of amphiphilic host molecule Alg-β-CD
[0035] Utilize mild Ugi reaction to synthesize amphiphilic polymer molecule Alg-β-CD, the steps are as follows:
[0036] Sodium alginate with a mass fraction of 2.5wt% was mechanically stirred at room temperature for 6h, diluted with water to a mass fraction of 2.0wt%, and the pH of the solution was adjusted to 3.6 with 0.5mol / L HCl solution, and formaldehyde (0.542mL ), cyclohexylis...
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