106results about How to "Has bactericidal activity" patented technology

The invention discloses a Gemini quaternary ammonium salt cationic surfactant with sterilization effect. The preparation method of the Gemini quaternary ammonium salt cationic surfactant disclosed by the invention relates to that a dihalide and a fatty amine are reacted in an organic solvent, i.e. a dibromo-matter and an alkyl tertiary amine perform chemical reaction in an ethanol (or acetone or ethyl acetate) solution at the room temperature or at a low temperature and normal pressure condition, so as to synthesize a series of Gemini quaternary ammonium salt cationic surfactants. The method for synthesizing the Gemini quaternary ammonium salt cationic surfactant is simple and convenient, stable in reaction process, easy for operating and controlling with a higher product purity and yield; besides, compared with the novel geramine, the method has better sterilization effect and has important application in the aspect of oil field germicide at the same time.

The invention provides 1,2,3-thiadiazole-1,3,4-thiadiazole derivatives, and a preparation method and application thereof. The invention relates to 1,2,3-thiadiazole-containing heterocyclic compounds with the chemical structural general formula shown as the specification. The invention discloses the structural general formula of the compounds, a synthesizing method of the compounds, application ofthe compounds serving as pesticides, bactericides, anti-plant-virus agents and plant activating agents, and a process for preparing the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents by mixing the compounds and agriculturally acceptable adjuvants or synergists. The invention also discloses application of the compounds when the compounds are combined withcommodities of the pesticides, the bactericides, the anti-plant-virus agents and the plant activating agents in prevention and control of agricultural, forestry, horticultural and health diseases, insect pests and virus diseases, and a preparation method of the compounds.

The invention discloses a substituent indole compound which is structurally shown as a general formula (I): the definition of each substituent group refers to an instruction manual. The compound has the bactericidal and insecticidal activity. The compound and another compound containing the compound as an active component are adopted for preventing and treating diseases of various crops and particularly have better prevention effect on pyriculariagrisea. A part of compound also has the insecticidal and acaricidal activity and can be used for preventing and treating pests and mites on the various crops.

The invention belongs to the technical field of biology engineering and particularly discloses an actinomycete strain KN37 and an application thereof. Through microscopic observation and 16S rDNA sequence analysis, the condition that the separated actinomycete strain KN37 belongs to Streptomyces is identified, and the preservation number of the actinomycete strain KN37 is CGMCC No.13160. A fermentation broth of the strain KN37 has a better inhibition effect on multiple phytopathogens such as Botrytis cinerea, Alternaria solani, Fusarium oxysporum, Fulvia fulva and the like and can be used for preparing microbial agents for controlling crop diseases.

This is a kind of acrylic zinc or cuprum resin containing indole functional group and its preparation method. Its characteristics are: firstly prepare monomer containing indole functional group, then synthesize acrylic resin containing functional group and carboxyl, finally make the acrylic resin and zinc hydroxide or cuprum hydroxide react to obtain acrylic zinc or cuprum resin containing indole functional group; the reaction temperature of the said synthesizing monomer containing indole functional group is -10 - 10 Deg. C, the reaction time is 1.5 - 5 hours. The resin of the invention can be used for preparing sea antifouling dope. In the seawater, the organic zinc or cuprum acrylic ester on the polymer linear main chain of the coat surface hydrolyzes, and send out organic zinc or cuprum; the hydrolyzed polymer main chain contains indole functional group with highly efficient antifouling activeness, which makes the hydrolyzed polymer main chain still has sterilization activeness. So the dope can effectively prevent halobios from clinging on the surface of fishing tools, ships and seacoast establishments, and has good antifouling performance.

The invention discloses a novel compound with bactericidal activity and provides a preparation method and application of the compound. The compound is an (E)-methyl 2-methoxyiminobenzeneacetate compound containing 1, 2, 4-triazole. The preparation method includes the step that the compound is formed by making a compound represented by a general formula II and a compound represented by a general formula III react. The compound has good bactericidal activity and can be applied to preparation of crop bactericide.

The invention relates to a sewage treatment method for a circulating cooling water system. The invention provides the sewage treatment method for the circulating cooling water system, wherein the method comprises a step of electrolyzing the sewage of the circulating cooling water system. By using the sewage treatment method for the circulating cooling water system, Cl- in the sewage of the circulating cooling water system can be effectively removed, the number of heterotrophic bacteria can be reduced to a certain degree, the corrosion rate is reduced, and the water quality reaches the requirement of recycled circulating cooling water; and in addition, the method provided by the invention is simple and convenient to operate, and has low cost.

The invention discloses a carbamic acid rotenone oxime ester having a chemical structural formula and a stereoscopic structural formula as shown in a formula I, and a preparation method of carbamic acid rotenone oxime ester I comprises the reaction between rotenone oxime and isocyanate in the presence of a phase-transfer catalyst or an acid binding agent. The carbamic acid rotenone oxime ester is obtained through filtration, washing and drying after the reaction is finished. The new carbamic acid rotenone oxime ester compound can be used for preparing pesticides and bactericides.

The invention discloses a nanocrystallization compound-type biological liquid fertilizer which has abundant nutrition, can avoid competition among microbial strains, even antagonism, improves microorganism component survival, prolongs product period of validity and is favourable for plant growth. The nanocrystallization compound-type biological liquid fertilizer comprises inorganic nutriment, organic nutriment, nanocrystallization aloe juice, nanocrystallization water, microorganism and kaolin, wherein the microorganism comprises at least three of actinomycetes, bacteria, mycete and saccharomycetes. The production method comprises: mixing the inorganic nutriment with the nanocrystallization water; successively adding the organic nutriment and the nanocrystallization aloe juice to mix to obtain a mixture A; adding the kaolin into the microorganism fermented and produced by each component; then, mixing the microorganisms mixed with kaolin into a mixture B; mixing the mixture A with the mixture B; and finally, adding aloietic acid.

The invention belongs to the field of agricultural fertilizer, relates to a foliage fertilizer, in particular to a foliage fertilizer for a longan tree and a production method of the foliage fertilizer. The foliage fertilizer is prepared from the following raw materials in parts by weight: 7 to 10 parts of biochemical fulvic acid potassium, 12 to 15 parts of urea, 5 to 7 parts of washing powder, 7 to 13 parts of monopotassium phosphate, 8 to 14 parts of amino acid-chelated copper and boron, 6 to 13 parts of sucrose-complexed manganese and calcium, 8 to 12 parts of diaminoferric xanthohumate, 1 to 2.5 parts of sophocarpidine, 14 to 20 parts of magnesium sulfate and 6 to 10 parts of zinc sulfate. The foliage fertilizer prepared by the production method disclosed by the invention is good in fertilizer efficiency, is rich in multiple medium trace elements required by the longan tree, and meets nutritional requirements of longan; after application, the foliage fertilizer has a significant prevention effect for physiological yellow coloring, small leaf, mottled leaf, roll leaf and the lime of the fruit tree; by using the foliage fertilizer, toot system development of the fruit tree can be promoted, disease invasion is prevented, and disease resistance, drought resistance and cold resistance of crops are improved; the foliage fertilizer has effects of improving the growth speed of longan, promoting fruiting and swelling, improving the yield and the quality of longan, improving the resistance of the fruit tree and sterilizing.

The invention discloses a rotenone oxime-ether with chemical structural formula as showed on the right. The preparation method of rotenone oxime-ether I and II comprises the following steps of: allowing the rotenone oxime, catalyst, alkali and aldylating agent to react in solvent and to be filtered, washed and dried after the reaction; and the rotenone oxime-ether is obtained. New compounds of the rotenone oxime-ether can be used for preparing insecticide and fungicide.

The invention discloses salicylic acid trans-(beta)-farnesene analogues as well as a preparation method and an application thereof, and belongs to the field of organic compound synthesis. The compound as shown in a formula I in the specification is obtained by the following steps of: mixing salicylic acid and analogues of salicylic acid, geraniol, geranylamine or substituted geranylamine serving as raw materials with an organic solvent, carrying out condensation reaction to obtain the salicylic acid trans-(beta)-farnesene analogues with different substitutes, and carrying out silica-gel column chromatography separation and purification. The preparation method of the compound as shown in the formula I has the advantages of mild reaction, simple and easy operation, relatively high yield and relatively low cost; and the compound is more stable than trans-(beta)-farnesene. The compound as shown in the formula I has multiple biological activities, relatively good killing activity to aphids at high dose, warning repellant activity to aphids at low dose, tobacco mosaic virus resisting activity and bactericidal activity, can be used for pest control and disease prevention in the agricultural production, and has relatively high application and development value.

The invention relates to 2-(1,2,4-triazole-1-methyl)-2-(coumarone-5-radical)-1,3-dioxolane with a chemical formula I shown in the description, where R is selected from C1-C2 alkyl radical and C3-C4 linear alkyl radical or branched alkyl radical, R1 selected from H and C1-C2 alkyl radical, X selected from chlorine,bromine,iodine, mesyloxy,trifluoro-mesyloxy, benzenesulfonyl oxy radical, and p-toluenesulfonyl oxy radical, and Y selected from hydrogen, C1-C2 alkoxy, C3-C4 linear alkoxy or branched alkoxy, chlorine, bromine, fluorine or iodine. The chemical formula I is prepared from a key intermediate II of a chemical formula II shown in the description; and a compound I can be applied to preparation of bactericide.

The invention provides a photodynamic sterilization polymer as well as a preparation method and application thereof. The polymer is composed of a main chain and a side chain; the side chain is composed of a long alkyl chain with a quaternized tail end and can be combined with the surface of bacteria with negative charge to form a tight combined body, so that a bacterial membrane is transparent; the main chain is composed of benzene, fluorene and thiophene and has a relatively strong rigid structure; under a light illumination condition, the main chain is excited by light to sensitize air in the periphery to generate active oxygen, so that an efficient sterilization effect is realized. The polymer can be used as an antibacterial agent and can be used for killing gram positive bacteria and gram negative bacteria; the polymer also can be used for killing fungi and has a broad-spectrum antibacterial function. The polymer is simple to prepare and moderate to react and has relatively high yield. The polymer is used as an efficient photodynamic antibacterial material, concentration needed by sterilization is low and the light dosage is small; common white illumination can reach an efficient sterilization effect. The polymer provided by the invention emits fluorescent light in a long-wave region and also can be used for biological fluorescent imaging.

The invention discloses an application of 4-(benzofuran-5-yl)-2-phenzyl aminothiazole as shown in the chemical structural formula I for preparing bactericide for killing sclerotinia sclerotiorum, wherein R is selected from C1-C2 alkyl, C3-C4 straight chain alkyl or branch chain alkyl; R1 is selected from H, C1-C2 alkyl, C3-C4 straight chain alkyl or branch chain alkyl; X is selected from 2-methoxyl, 3-methoxyl, 4-methoxyl, 2-ethoxyl, 3-ethoxyl, 4-ethoxyl, 2-trifluoromethoxyl, 3-trifluoromethoxyl and 4-trifluoromethoxyl.

The invention provides a B-group epidemic neisseria meningitidis recombinant protein vaccine and a preparing method thereof, and belongs to the field of biological products. The vaccine contains three mutant recombinant proteins of a human H factor binding protein. The invention further provides a preparing method of the B-group epidemic neisseria meningitidis recombinant protein vaccine. The method includes the steps of human H factor binding protein V1, V2 and V3 recombinant expression carrier construction, expression strain screening and identification, fermental cultivation, recombinant protein antigen inducible expression and recombinant protein antigen purification and protein detection; and according to the concentrations of the three antigen components, quantified mixing is carried out, and the B-group epidemic neisseria meningitidis recombinant protein vaccine is prepared in cooperation with an aluminum adjuvant. By means of the B-group epidemic neisseria meningitidis recombinant protein vaccine, intraperitoneal injection is carried out on an immune mice, the mice body can be stimulated to generate a B-group epidemic neisseria resisting peculiar antibody, and the alexin mediated serum sterilization antibody can rise by more than 8 times.

Topical compositions containing an effective amount of lysostaphin and / or one or more lantibiotics in a pharmaceutically acceptable carrier for topical application. Methods for treating skin or wound infections, including, but not limited to infected abrasions, skin or surface cuts, burns or surgical incisions or decubiti, with the topical compositions are also disclosed.

The invention discloses an oxadiazole compound containing pyridine, a preparation method of the oxadiazole compound containing pyridine and application of the oxadiazole compound containing pyridine in prevention and control of tomato bacterial speck, cucumber fusarium wilt and botrytis cinerea, wherein the compound is shown in a formula (I). The compound provided by the invention is a new compound with bactericidal activity and provides a base for research and development of new pesticides. The formula (I) is shown in the specification.

The invention discloses a HBD3 mammary gland specific expression vector and a constructed recombinant cell. The vector comprises a HBD3 gene with a signal transduction peptide, and CSN5 and CSN3 are set upstream and downstream of the HBD3 gene respectively for serving as regulating and controlling elements. The host cell of the recombinant cell is a bovine fetal fibroblast cell, an exogenous expression vector pARNG-HBD3 is integrated to a pseudo attP locus under the action of phiC31 integrase, positive cloning is realized through medicament screening, and an antibiotic screening marker between two homodromous LoxP sequences on the vector is removed through Cre recombinase treatment. A HBD3-containing bovine fetal fibroblast cell from which an antibiotic screening marker is removed is taken as a nuclear donor cell of a transgenic cloning embryo through nucleus transplantation, gene cloning embryos are obtained through SCNT (Somatic Cell Nuclear Transfer), and a milk cow which is free from a HBD3 transgenic gene of the antibiotic screening marker can be produced by transferring these embryos into a receptor cow.

The invention discloses a compound biological pesticide and application thereof. The compound biological pesticide is prepared from red bisabolane type sesquiterpenoids compounds, such as one or moreof turmeronol A, turmeronol B, 8-hydroxy-ar-turmerone, alpha-curcumene and (+)-(S)-ar-turmerone. Further, the compound biological pesticide also includes at least one of fungicide or insecticide selected from matrine, veratrine, osthole, berberine, azadirachtin, abamectin and rotenone. The compound biological pesticide disclosed by the invention has the advantages of low toxicity, high efficiency,strong selectivity and the like, and also has a relatively good prevention and control effect on diseases and insect pests including downy mildew, gray mold, aphids, plutella xylostella, red spiders,cnaphalocrocis medinalis, whitefly and the like in the aspect of the effect of preventing and controlling powdery mildew; the yield of crops including cucumbers and the like is remarkably improved by10 percent to 50 percent, the dosage of a biological pesticide is effectively reduced, and the environment pollution is alleviated; the compound biological pesticide is friendly to people and environment, and meets the requirements on green agricultural development.

The invention relates to N-[4-(benzofuran-5-yl)thiazole-2-yl] amide shown in a chemical structural formula I and the salts thereof, wherein Y, R1, R and R2 are selected from hydrogen, C1-C2 alkyl, C3-C4 linear alkyl or branched alkyl and the like; and N-[4-(benzofuran-5-yl)thiazole-2-yl] amide is prepared from 4-(2,3-dihydrobenzofuran-5-yl)-2-aminothiazole via acylation. N-[4-(benzofuran-5-yl)thiazole-2-yl] amide is good in bactericidal activity, and capable of being applied in preparation for a bactericide.

The invention discloses isoptericola and a method for using the isoptericola for synthesizing nano silver. The strain is Isoptericola sp. SYSUZL-3, preserved in China Center for Type Culture Collection on January 5, 2017 under the accession number of CCTCC NO:2017006. The strain has the ability to produce nitrate reductase to reduce silver ions for further synthesizing the nano silver. The strainSYSUZL-3 is activated, cultured, and centrifuged to obtain supernatant. A silver nitrate solution is added to the supernatant, and the nano silver is obtained by light irradiation. The nano silver hassmall particle size and high yield, and has obvious inhibitory effect on the growth of pathogenic bacteria such as Staphylococcus warneri, and sunlight is used to catalyze the reaction, and the synthesis efficiency is greatly improved. The synthesis method is low in production cost, simple in operation, non-pollution to the environment, and green, and has a good application prospect.

The invention relates to an asymmetric heterocyclic ring substituent urea compound and a preparation method and application thereof. The compound is a compound or a non-toxic salt thereof with a structure shown in the formula I, wherein R1 is selected from halogen, nitryl, cyan, hydroxyl, ester group, carboxyl, trifluoromethyl, alkyl, alkoxyl, aryl, heteroaryl, aryloxy, acyl, acyloxy or heterocyclic radical; and R2 is selected from alkyl, aryl, heteroaryl or cluste aryl. The asymmetric heterocyclic ring substituent urea compound has the characteristics of weeding activity, sterilizing activity and plant growth adjusting activity; and the preparation method is safe and non-toxic.

The invention relates to a monoterpene phenolic derivative, a synthetic method of the monoterpene phenolic derivative and application of the monoterpene phenolic derivative in pesticides, in particular to application of the monoterpene phenolic derivative in the aspect of fungicide pesticides, and belongs to the technical field of pesticides. The technical aims of a new monoterpene phenolic derivative, a synthetic method of the new monoterpene phenolic derivative and application of the new monoterpene phenolic derivative in pesticides are achieved, and the structure of the compound is shown inthe formula I. The compound is simple in structure, novel, easy to synthesize, also has the fungicidal activity, and has a good bacteriostatic or sterilizing effect on important plant pathogenic fungi such as alternaria solani, botrytis cinerea, cucumber fusarium wilt, magaporthe grisea and rice sheath blight fungi.

The invention belongs to the field of deodorizing products and relates to a natural plant-derived environment-friendly deodorant. The deodorant comprises fruit extract liquid, plant extract liquid, anonionic surfactant, a cationic surfactant and purified water. The fruit extract liquid contains polyphenols; the plant extract liquid contains alkaloid, and an aqueous solution of the alkaloid is alkaline; the cationic surfactant is a metal salt cationic surfactant. Under the action of alkaloid, deodorizing effects of the polyphenols are improved, deodorizing time is shortened, and effective deodorization is realized. The deodorant is capable of fundamentally eliminating various odors by simultaneous action on acids, alkalis and repugnant substances; by adding of an essential oil component, integral fragrance of the deodorant is enriched; by a reasonable ratio, functions and aroma of the deodorant satisfy users, and secondary pollution is avoided.

The invention relates to hand-washing mousse containing wild jujube core and shell wood vinegar and a preparation method and application of the hand-washing mousse. The hand-washing mousse is prepared from the following raw materials in percentages by mass: 5-20wt% of the wild jujube core and shell wood vinegar, 5-40wt% of a foaming agent, 0.1-1.5wt% of essential oil, less than or equal to 0.02wt% of a food-grade preservative, and the balance of acidic electrolyzed water; and the sum of weight percentages of the raw materials is 100wt%. The preparation method comprises the following steps: evenly mixing the wild jujube core and shell wood vinegar, the foaming agent, the essential oil and the food-grade preservative proportionally; taking the acidic electrolyzed water with the suitable amount so that the sum of the weight percentages of the raw materials is 100wt%; and packing the raw materials in a mousse foaming bottle to obtain the final product. The prepared hand-washing mousse has effects of sterilizing, protecting and improving the skin, has the remarkable characteristics that the hand-washing mousse is purely natural and safe, and does not have side effects, and is wide in application prospect.

The invention discloses a quinoline 4-hydroxypicolinate compound. The compound has the following structure shown in the specification, wherein R is F, Cl or OCH3. The preparation method comprises thefollowing specific preparation steps: enabling 6-trifluoromethyl-4-quinolinol and 7, 8-dimethoxy-4-quinolinol to respectively react with 2-substituted pyridine-3-formic acid under the conditions of acatalyst, a condensing agent and an organic solvent so as to prepare quinoline 4-hydroxypicolinate compounds (I) and (II). The compounds (I) and (II) have a good prevention effect on magnaporthe oryzae. The preparation methods of the compounds (I) and (II) are simple to operate, high in yield and stable in product property.

The invention discloses a soil restorative agent for treating heavy metal pollution and a preparation process of the soil restorative agent. The soil restorative agent is mainly prepared by adopting an organic fertilizer, a microbial agent, matrine, pyrethrum, derris, chlorothalonil and agritol powder. The weight percent of each raw material is as follows: 280 to 320 parts of organic fertilizer, 28 to 32 parts of microbial agent, 0.03 to 0.07 part of matrine, 0.05 to 0.1 part of pyrethrum, 0.03 to 0.09 part of derris, 0.04 to 0.08 part of chlorothalonil and 0.02 to 0.06 part of agritol powder. The organic fertilizer is used as a main raw material, the microbial agent for alleviating the harm of soil heavy metal and salt and alkali is added, an insecticidal effect and a sterilizing effect can be simultaneously achieved, the soil restorative agent can further enter the soil, and the soil polluted by the heavy metal can be improved.

The invention discloses a fluorine-containing nicotinyl urea compound. The structural formula of the fluorine-containing nicotinyl urea compound is as shown in the specification. In a formula (I), H on a benzene ring is monosubstituted or polysubstituted by substituent groups R, wherein n is an integer from 1 to 5 and represents the number of the substituent groups R on the benzene ring; when n is1, H on the benzene ring is monosubstituted by the substituent group R; when n is from 2 to 5, H on the benzene ring is polysubstituted by the substituent groups R; and the substituent groups R on different substituent positions are same or different. The invention also provides a preparation method and application of the fluorine-containing nicotinyl urea compound. As a bactericide, the fluorine-containing nicotinyl urea compound is used for inhibiting botrytis cinerea, gibberella zeae, sclerotinia sclerotiorum or physalospora piricola.