The invention discloses a compound fertilizer for solanum tuberosum growth and a preparation method thereof, and relates to the field of fertilizers. The compound fertilizer is prepared from, by weight, 15-20 parts of seaweed, 7-12 parts of sawdust, 10-15 parts of melon vine, 25-30 parts of faeces, 5-10 parts of calcite, 15-20 parts of modified attapulgite, 5-10 parts of seafood shell, 5-10 partsof nut shell, 3-8 parts of starchy residue, 4-9 parts of tofukasu, 4-9 parts of tealeaf residue, 10-15 parts of grass carbon, 4-9 parts of melia azedarach, 4-9 parts of thunder god vine, 3-8 parts oftrace element additive and 3-8 parts of microbial strain. The compound fertilizer for the solanum tuberosum growth and the preparation method thereof have the advantages that the fertilizer has abundant nutrient substances, the fertilizer efficiency action period is long, the fertilizer not only can be provided for the growth and adsorption of plants, but also can improve soil activity and loosenthe soil, the sources are wide, and the preparation method is simple.