Provided are a lithium boron alloy production process, and device thereof. The process includes mixing lithium and boron, heating to 400 DEG C. under high-purity argon gas atmosphere, stirring and reacting for 2h, heating to 450 DEG C. to form molten alloy, casting into a mold, continuously heating to 650 DEG C., and reacting for 1h till to hardening; and cooling to the alloy billet to room temperature, demolding, and packaging. The device includes a first transition bin, a synthesis box body, a cold well, a glove box and a second transition bin; two adjacent units are in sealed connection and spaced via a sealed bin gate, and each unit is connected with an argon gas purification device, respectively; the synthesis box body is provided with a first heating region and a second heating region, the first heating region is provided with a stirring device, and the heating body thereof can be turned over. By adopting innovative double-heating region staged reaction and synthesis, casting and transport under the protective atmosphere, the process prevents generation of various defects in the synthesis process of the lithium boron alloy, reduces the difficulty of the product subsequent processing and realizes energy saving and yield increase as well.