The invention belongs to the field of
chemistry, and relates to a synthetic method of asymmetrical
thioether. The synthetic method comprises the following steps of (a) under the condition of
catalysis of tetrabutyl
ammonium halide, enabling a structural compound as shown in a formula (I), a structural compound as shown in a formula (II) and
sulfur oxonium salt to react in a
solvent so as to obtain the asymmetrical
thioether with a structure as shown in formula (III), wherein R1 is selected from phenyl, substituted phenyl, naphtyl, substituted naphtyl, thienyl, or substituted thienyl; R2 is selected from
hydrogen, phenyl, substituted phenyl, naphtyl, substituted naphtyl, thienyl or substituted thienyl; or R1, R2 and C connected with R1 and R2 form
fluorene or
thioxanthene; R3 is selected from
hydrogen or an
alkyl group; R4 is selected from
hydrogen, phenyl, substituted phenyl, naphtyl, substituted naphtyl, thienyl or substituted thienyl; R5 is selected from hydrogen; or R4, R5 and C connected with R4 and R5 form the
fluorene or the
thioxanthene; R6 is selected form the
alkyl group or the substituted
alkyl group; and X is selected from C1, Br or I.