The invention discloses a compound pesticide for fishing; the compound pesticide can be used for preventing aquatic livestock parasitic diseases caused by parasites such as trichodina, dactylogyrus, gyrodactylus, Chinese daphnia, lernaean, sporozoit and the like, belonging to the field of veterinary drugs. The ingredients of the compound pesticide for fishing are composed of radix sophorae flavescentis, betel palm, stone-like omphalia and cypermethrin; the preparation method of the compound pesticide is that: the radix sophorae flavescentis, betel palm and stone-like omphalia are weighted according to the proportion, refluxing and extraction are carried out, extracting solution is heated, evaporated and concentrated, and then cypermethrin, emulsifying agents, organic solvent and distilled water are added for preparation according to the proportion; the compound pesticide for fishing has the advantage of stable quality, convenient usage, low cost, having remarkable curative effect on the trichodina, dactylogyrus, gyrodactylus, Chinese daphnia, lernaean, sporozoit diseases of the aquatic livestock, rapid effect, thorough killing, small toxic and side effect and wide parasite expelling and killing spectra, and can effectively ensure health and safety of aquaculture animals.