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69 results about "Protein allergy" patented technology

Milk protein is a common allergen. Many different chemicals and compounds in food can trigger allergic reactions. Protein, especially from dairy products, shellfish and nuts, is a very common allergy trigger in children and adults.

Natural rubber liquid slurry containing chitosan/sericin and preparation method thereof

ActiveCN101717530AImprove the preservation effectOvercome stickiness due to agingSlurrySericin
The invention discloses a natural rubber liquid slurry containing chitosan/sericin and a preparation method thereof, and belongs to the field of high polymer chemistry. The invention is characterized in that the preparation method comprises the following steps: respectively preparing a chitosan water solution and a sericin water solution, mixing the two solution, and regulating the pH value of the mixture to 9-11 by using ammonia water and a citric acid solution; and adding the obtained chitosan/sericin mixed solution to a natural latex slurry, adding a laurate surfactant, and mechanically stirring the mixture uniformly to obtain the natural rubber liquid slurry containing chitosan/sericin. The invention has the advantages that the chitosan has the functions of adsorbing water soluble proteins in the latex, inhibiting bacteria and viruses from breeding, and the like; and the sericin has the functions of oxidation resistance, allergy resistance, hydrophilia, oil resistance and the like, thereby enhancing the emulsion phase stability and the preservation effect of the natural latex. In particular, the product obtained by using the method overcomes the defects of short service life, easy aging and sticking, poor oil resistance, initiation of protein allergy and the like in the traditional natural latex product.
Owner:湖南万橡新材料科技有限公司

Supression of allergic reactions by transdermal administration of allergens conjugated to cholera toxin or fragments thereof

The present invention discloses the use of the non-toxic cell-binding B subunit of CT (CTB), and holotoxin CT that is devoid of ADP-ribosylating activity, as adjuvants for enhancing transcutaneous immune response to a co-administered protein allergen. It was found that topical administration of CTB to mice induced serum antibody response against itself comparable to those evoked by CT, but was inefficient at promoting systemic antibody responses against an admixed prototype protein allergen. To the contrary co-administration of either CT or CTB with allergen led to vigorous antigen-specific T cell proliferative responses in lymph nodes draining the cutaneous site of administration and at distant systemic sites. Consistent with these observations, it was found that CTB selectively potentiated Th1-driven responses without affecting Th2-dependent responses. Cutaneously applied CT enhanced serum IgE responses to a co-administered allergen, while CTB partially suppressed epicutaneously induced IgE responses to the same allergen.
Owner:DUOTOL

Method for preparing powder rich in whey small peptides with molecular weight of 1000 daltons

InactiveCN101518295ASolve the problem of prominent bitterness after high degree of hydrolysisEnhance physical fitnessAnimal proteins working-upAdditive ingredientInfants milk
A method for preparing powder rich in whey small peptides with molecular weight of 1000 daltons belongs to the technical field of processing dairy products. The main production process thereof is as follows: enzymatic hydrolysis, embedding and homogenization are firstly carried out on concentrated powder (WPC80 powder) containing 80 percent of whey protein, then the powder is prepared by spray drying, and the product can be used as functional ingredients for infant milk powder. The method adopts trypsin for enzymatic hydrolysis, the degree of hydrolysis achieves 20-21 percent, and then hydrophilic-hydrophobic wall materials of 5-10 percent of beta-cyclodextrin and 5-8 percent of lecithin are adopted, so the method can not only bury the bitterness, but also maintain the biological activities of anti-protein allergy and improve the immunity of the whey small peptides with the molecular weight of 1000 daltons to the maximum extent. The method can be applied to the infant formula milk powder and have good effects of improving the ability of anti-protein allergy of the infant milk powder and improving the immunity.
Owner:ZHEJIANG UNIVERSITY OF SCIENCE AND TECHNOLOGY

Medical security level rubber product with sericin modified surface and preparation method thereof

A medical security level rubber product with sericin modified surface and a preparation method thereof belong to the technical field of the production technology of rubber and latex products. The invention discloses a sericin composite which is used for the rubber product modification so as to increase the medical security. The rubber product is characterized in that sericin, natural polysaccharides, biological protein, bio-enzyme, organic acid and salt coexist according to a certain proportions. The invention also discloses a preparation method of the rubber product. The method is characterized in that sericin composite is coated on the surface of the rubber product; and / or the sericin composite is added in the natural latex to be vulcanized, and the sericin composite migrates to the surface of the rubber product owning to the hydrophilicity during the rubber vulcanization process and forms a hydrophilic protective film so as to prevent the allergenic protein and chemical additives in the rubber product to precipitate. The positive effect of the invention is as follows: the rubber product can be used to modify the latex protein so as to increase the strength of the rubber and reach the aim of not inducing the protein allergic reaction. Therefore, the sericin waste resource is developed for recycling so as to save the resource and protect the environment.
Owner:湖南万橡新材料科技有限公司

T cell epitopes of the major allergens from dermatophagoides (house dust mite)

The present invention provides isolated peptides of the major protein allergens of the genus Dermatophagoides. Peptides within the scope of the invention comprises at least one T cell epitope, or preferably at least two T cell epitopes of a protein allergen selected from the allergens Der p I, Der p II, Der f I, or Der f II. The invention also pertains to modified peptides having similar or enhanced therapeutic properties as the corresponding, naturally-occurring allergen or portion thereof, but having reduced side effects. The invention further provides nucleic acid sequences coding for peptides of the invention. Methods of treatment or of diagnosis of sensitivity to house dust mites in an individual and therapeutic compositions comprising one or more peptides of the invention are also provided.
Owner:MERCK PATENT GMBH

Method for altering allergenic protein in the environment

InactiveUS7704532B1Prevention and material mitigation of allergic reactionAllergenicity reductionBiocideCosmetic preparationsAntigenPollen
Described are compositions and methods for use thereof for prevention or mitigation of allergic reactions in humans and animals. Novel compositions comprised of, e.g., an acidic salt solution of aluminum, calcium or magnesium, are provided for topical or contact application to physically and / or chemically alter an allergenic protein present in the environment and thereby lower the allergenicity of the protein. The compositions of the invention, e.g., comprised of aluminum sulfate, can be used to deactivate many types of proteinaceous allergens such as dust mite and cockroach body dust, animal dander, dried saliva, mold spore antigens, airborne pollen protein and the like. Compositions can be applied on an as needed basis to a wide variety of surfaces, interiors, furniture, pet bedding, plants and the like. The compositions provided may also be utilized to mitigate allergens present on clothing, e.g., for use in commercial dry cleaning or in household laundry applications.
Owner:SMITH C STEVEN

Amino Acid And Protein Hydrolysate Based Formulas With A Stable Emulsion System

The present disclosure relates in part to an emulsion system comprising a waxy starch. The emulsion system is useful, in some embodiments, for incorporation into infant formulas comprising protein equivalent sources, such as formulas designed for individuals with certain protein allergies. Thus, in certain embodiments, the present disclosure relates to a nutritional composition comprising a protein equivalent source comprising a hydrolyzed protein, amino acids, or a mixture thereof, a fat source, a carbohydrate source, and an emulsifier system comprising a waxy starch. The emulsifier system may further include citric acid esters of mono- and di-glycerides or an octenyl succinic acid-modified starch, or both.
Owner:MEAD JOHNSON NUTRITION

Cloning and sequencing of allergens of dermatophagoides (house dust mite)

Isolated DNA encoding allergens of Dermatophagoides (house dust mites) particularly of the species Dermatophagoides farinae and Dermatophagolides pteronyssinus, which are protein allergens or peptides which include at least one epitope of the protein allergen. In particular, DNA encoding two major D. farinae allergens, Der f I and Der f II and DNA encoding a D. pteronyssinus allergen, Der p I. In addition, the proteins or peptides encoded by the isolated DNA, their use as diagnostic and therapeutic reagents and methods of diagnosing and treating sensitivity to house dust mite allergens.
Owner:MERCK PATENT GMBH

Powder latex glove and non-powder latex glove dual-purpose production line and powder latex glove and non-powder latex glove dual-purpose production method

The invention relates to a powder latex glove and non-powder latex glove dual-purpose production line and a powder latex glove and non-powder latex glove dual-purpose production method. The productionline comprises a rack. A glove die circulation conveying mechanism is arranged on the rack. The glove die circulation conveying mechanism comprises a conveying motor fixed to the rack, a drive chainwheel, a driven chain wheel, a conveying chain, a middle chain wheel, a main guide rail fixed to the rack and an auxiliary guide rail fixed to the rack. The conveying chain is arranged along the mainguide rail. Multiple glove dies matched with the auxiliary guide rail are hinged to the two sides of the conveying chain correspondingly, and a latex glove die cleaning device, a latex glove forming device, a latex glove protein removing and adhesion preventing treatment device, a latex glove hemming device, a latex glove adhesion preventing powder spraying treatment device and a latex glove die releasing device which are located below the glove die circulation conveying mechanism are sequentially arranged on the rack in the glove die circulation conveying direction. By means of the powder latex glove and non-powder latex glove dual-purpose production line and the powder latex glove and non-powder latex glove dual-purpose production method, gloves which are not likely to cause protein allergy and convenient to wear can be produced, and circulated and automatic production is achieved in the whole process.
Owner:福建海创智能装备股份有限公司

Natural rubber liquid slurry containing chitosan/sericin and preparation method thereof

ActiveCN101717530BImprove the preservation effectOvercome stickiness due to agingSlurryHigh polymer
The invention discloses a natural rubber liquid slurry containing chitosan / sericin and a preparation method thereof, and belongs to the field of high polymer chemistry. The invention is characterized in that the preparation method comprises the following steps: respectively preparing a chitosan water solution and a sericin water solution, mixing the two solution, and regulating the pH value of the mixture to 9-11 by using ammonia water and a citric acid solution; and adding the obtained chitosan / sericin mixed solution to a natural latex slurry, adding a laurate surfactant, and mechanically stirring the mixture uniformly to obtain the natural rubber liquid slurry containing chitosan / sericin. The invention has the advantages that the chitosan has the functions of adsorbing water soluble proteins in the latex, inhibiting bacteria and viruses from breeding, and the like; and the sericin has the functions of oxidation resistance, allergy resistance, hydrophilia, oil resistance and the like, thereby enhancing the emulsion phase stability and the preservation effect of the natural latex. In particular, the product obtained by using the method overcomes the defects of short service life, easy aging and sticking, poor oil resistance, initiation of protein allergy and the like in the traditional natural latex product.
Owner:HUNAN VONTEX NEW MATERIAL TECH CO LTD

Protein allergens of the species cynodon dactylon

InactiveUS7514083B1Peptide/protein ingredientsSnake antigen ingredientsBermuda grass pollenBermuda grass pollen allergen
The present invention provides nucleic acid sequences coding Cyn d I, or at least one fragment thereof or the functional equivalent of such nucleic acid sequences. The present invention also provides expression vectors comprising such nucleic acid sequences and host cells transformed therewith. The present invention further provides isolated Bermuda grass pollen protein allergen Cyn d I or fragments thereof. Isolated Bermuda grass pollen protein allergens or antigenic or allergenic fragments thereof are useful for diagnosing and treating sensitivity in an individual to Bermuda grass pollen allergens.
Owner:HESKA

Method for immobilizing proteins in natural rubber latex by aid of modified tannin extract

The invention discloses a method for immobilizing proteins in natural rubber latex by the aid of modified tannin extract. The method is characterized by comprising steps of adding, by weight, more than 0.2 part of solid modified tannin extract into 100 parts of natural rubber latex and carrying out film formation, leaching, drying and vulcanization processing on rubber products according to conventional proportions and processes for the rubber products. The contents of extractable water-soluble proteins in the prepared rubber products are lower than 100 micro-g/dm<2>; the rubber products are natural rubber glove products manufactured by means of impregnation; the natural rubber latex is high-ammonia concentrated latex; the modified tannin extract is a modified product of powdery tannin extract which is a commercially available commodity. The method has the advantages that the modified tannin extract prepared by means of one-step reaction is used as a protein immobilizing agent, accordingly, the problem of protein allergy of existing natural rubber products can be solved, the mechanical properties, the ageing resistance and the hydrophilic performance of the rubber products can be improved, and the application range of tannin extract can be expanded.
Owner:YUNNAN NORMAL UNIV
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