The invention discloses a medicine for treating skin disease and hairdressing. The medicine has the brook anemone as primary material and can combine with the other plants, which selects from one of Blumea balsamifera Dc, Chinese alangium root, delavay ampelopsis root, corn mint or chinarue, or their mixture; in which, the weight ratio of the brook anemone and other plants is 1:100-100:1. The inventive medicine can be used to treat skin moisture and skin disease, such as acne, dermatitis, tetter, flat wart, psora, pityriasis, psoriasis, skin polypus tumor, corporality inductivity skin hypersensitivity and pruritus, dermatophytosis, foot odour, underarm odour, and dander.