The invention relates to a broad-spectrum antibacterial wound
nursing membrane and a preparation method thereof and belongs to the field of
biological materials. The broad-spectrum antibacterial wound
nursing membrane takes degradable aliphatic
polyester and degradable
natural polymers as main raw materials, a non-dissolving type cation
antibacterial agent is added, the
antibacterial agent and a
polymer undergo chemical crosslinking effects, so that antibacterial groups are bonded to a
spinning matrix, and an antibacterial
nanofiber membrane is prepared through an electrostatic
spinning method to be used for the wound
nursing membrane. The wound nursing membrane has broad-spectrum
antibacterial property, has obvious killing and inhibiting effects on
gram-positive
bacteria,
gram-negative
bacteria,
saccharomycetes and fungi in an infection period and can effectively inhibit bacterial infection to the wound part; an antibacterial mechanism is cation
antibiosis, the wound nursing membrane has low
drug resistance, and a non-dissolving type
antibacterial agent has a lasting
antibacterial effect. Besides, the wound nursing membrane has excellent
biocompatibility,
mechanical property, breathability and water absorption property. The broad-spectrum antibacterial wound nursing membrane can serve as a wound nursing membrane.