43 results about "Phytoalexin" patented technology

The invention provides a composition useful in the construction industry for the prevention or remediation of mold growth in a man made structure. The composition contains an extruded milo matrix incorporating terpenes, phytoalexins, calcium propionate or combinations of these chemicals having antifungal activity. Methods of making and using the compositions are also disclosed.

The technology provides a multi-purpose dietary supplement that includes, in nutritionally effective amounts for humans, an orally ingestible combination of antioxidants, naturally-occurring substances and extracts of naturally-occurring substances. The naturally-occurring substances and extracts of naturally-occurring substances include at least: finely divided silica hydride; a polyphenol; ginkgo biloba leaf extract; rhodiola rosea root; bacopa monniera extract; a glutathione precursor; a phytoalexin; a bioflavonoids; CoQ10 and a phospholipid.

The flavonoid family of phytochemicals, particularly those derived from soy, has received attention regarding their hormonal activity and their effects on human health and disease. The types and amounts of these compounds in soy and other plants are controlled by both constitutive expression and stress-induced biosynthesis. The health benefits of soy may therefore be dependent upon the amounts of the various hormonally active phytochemicals present. We have identified increased biosynthesis of the isoflavonoid phytoalexin compounds, Glyceollins I, II and III, in soy plants grown under stressed conditions (elicited soy), which exhibit marked anti-estrogenic effects on ER function. Here we demonstrate that specific glyceollins, isolated from elicited soy, displayed anti-estrogenic activity, suppressing basal and estrogen stimulated colony formation of ER-positive estrogen dependent breast cancer cells and inhibiting ER-dependent gene expression of progesterone receptor (PgR) and stromal derived factor-1 (SDF1 / CXCL12). Examining the effects of glyceollin on in vivo tumor formation / growth we demonstrate the ability of glyceollins to significantly suppress basal and estrogen-stimulated tumor growth of ER-positive MCF-7 breast and BG-1 ovarian carcinoma cells in ovariectomized female nude mice. We further demonstrate that the effects of glyceollins on suppression of tumor growth correlate with inhibition of estrogen stimulated PgR expression. In contrast to the uterotropic activity of tamoxifen the glyceollins displayed no uterine agonist activity. The Glyceollin (I-III) compounds may represent an important component of the health effects of soy as well as represent novel anti-estrogens useful in the prevention or treatment of breast and ovarian carcinoma.

Methods of genetically manipulating biology active 4′-O-methylated isoflavonoids have been found based upon the regiospecifity of isoflavone 7-OMT in vivo. Upon transformation and expression of an isoflavonoid O-methyltransferase gene, up-regulation of IOMT in the transgenic plants can be used to increase the accumulation of 4′-O-methylated isoflavonoid phytolalexins, providing for increased disease resistance to the plant. Similar methods can be used to increase accumulation of 4′-O-methylated isoflavonoid nutraceuticals in plants. For down-regulation of IOMT in plants that naturally make 4′O-isoflavonoid phytoalexins and 4′-O-methylated isoflavonoid nutraceuticals, IOMT gene sequences can be transformed in the antisense orientation.

The invention provides a cultivation method for improving the quality of potted rhododendrons, which belongs to the technical field of rhododendron cultivation, including transplanting cutting seedlings of rhododendrons, applying biological compound fertilizer, inoculating with ERM bacterial agent, and managing potted rhododendrons; wherein, ERM The preparation method of the bacterial agent is as follows: activate the strain of ERM and inoculate it into the liquid medium, cultivate it in a shaker at a temperature of 23-26°C and rotate at a speed of 140-160r / min for 8-12d, filter, and wash the hyphae with sterile water After several times, disperse in sterile water containing sodium glucuronate and dextran 40. This method can promote root tip meristem to carry out meridian division, increase the thickness of cortex, improve the ERM mycorrhizal infection rate of Rhododendron sinensis, improve the growth quality of Rhododendron sinensis; can promote the phenylalanine ammonia-lyase ( The expression of PAL) gene can improve the activity of PAL, promote the synthesis of phytoalexin, and improve the disease resistance of potted rhododendron.