The invention discloses an infrared spectroscopy on-line quality monitoring and controlling system applied to anaesthetic preparations. The infrared spectroscopy on-line quality monitoring and controlling system comprises the following steps: A, a collector on a multi-functional extracting pot is used for collecting the infrared spectroscopy of a solution on line, sampling is carried out at the same time, and the content of chlorogenic acid and schaftoside is measured off line; B, a collector on a concentration pot is used for collecting the infrared spectroscopy of the solution on line, sampling is carried out at the same time, and the content of index components is measured off line; C, the infrared spectroscopy and content data obtained from the step A and the step B, of a sample is inputted into a computer to obtain the content of the index components so as to realize real-time monitoring of the index components; D, the content of the index components obtained from an on-line analysis mathematic model is inputted into a distributed control system through an OPC communication module, and an self-controlling valve field actuator in anaesthetic preparation equipment is controlled to realize the feedback control of the anaesthetic preparations in the preparing process. According to the invention, the content of the index components can be monitored in real time, and the feedback of anaesthetic composition in the preparing process can be realized.