139 results about "Periodontium" patented technology

A laser system and method are described that will improve dental treatments in small animals, particularly in situations where periodontal disease has progressed to the advanced stages of periodontitis and when dental pulp is exposed by fracture or disease. A laser system is employed to achieve enhanced precision by selectively ablating affected tissue without damaging the collateral tissue. The laser system is also capable of sealing the tubules and eradicating bacteria within the periodontium to significantly reduce the risk of infection. Additional pre-treatment methods may be employed to further enhance the laser therapy.

A method of selectively treating microbiological pathogens which are implicated in the advancement of periodontitis is disclosed. Preferably, the microbiological pathogens are phorphyromonas gingivalis (Pg) and prevotella intermedia (Pi) which are known to colonize in dental plaque, cementum, gingival sulcus epithelium and surrounding periodontal tissues. The microbiological pathogens can also include pigmented fungi such as Histoplasma and Aspirgillus Niger. The microbiological pathogens are selectively irradiated with high-energy antiseptic laser pulses which are strongly absorbed by the microbiological pathogens and which are substantially transparent to the periodontal tissues. Preferably, high-energy antiseptic laser pulses eradicate a portion of the microbiological pathogens within the periodontal tissues without requiring aggressive debridement procedures.

The invention discloses a modeling method of an oral cavity model used for an individual three-dimensional orthodontic force test. The modeling method comprises the following steps of: 1) performing CT data acquisition; 2) rebuilding a three-dimensional model of an oral cavity tissue; 3) correcting bended dedendums of molars with multiple dedendums; 4) designing a parodontium; 5) removing an amplified tooth model from an alveolar bone model without dedendum fossa; 6) designing a guide plate used for locating a correct position of a tooth in the tooth fossa; 7) designing a base of the oral cavity model; 8) processing the teeth, the alveolar bone and the guide plate by using a hard material through a rapid proto-typing technology; 9) mixing a silica gel material for sealing and an elastic material to serve as a simulated material of the parodontium; and 10) filling the simulated material of the parodontium into the dedendum fossa on the alveolar bone and then inserting the teeth to finally obtain an oral cavity orthodontic force measurement and simulation model. The modeling method of the oral cavity model used for the individual three-dimensional orthodontic force test can obtain precise correcting force and torque, has relatively good reliability, and can efficiently guide an individual orthodontic force test model of an individual orthodontics schematic design.

The invention generally relates to postnatal periodontal ligament stem cells and methods for their use. More specifically, the invention relates in one aspect to postnatal periodontal ligament multipotent stem cells, use of the cells to generate periodontium, differentiation of the cells and methods of tissue cryopreservation.

The invention discloses a boron-containing nano-mesoporous and macroporous bioactive glass, a preparation method thereof and the application thereof to medical supports. The boron-containing mesoporous bioactive glass is prepared by substituting BO33- for part of SiO44- by a sol-gel method. According to the method, controllable porosity (78 to 90 percent) is obtained by adjusting immersion times (2 to 5 times) and aperture (300 to 500 microns). The composite glass material has pores suitable for cell growth; tissue growth and nutrition transmission are facilitated due to the porosity characteristic; and the structural integrity of the supports can be maintained in vitro. When the boron content is 0 to 10 percent, the boron-containing ordered mesoporous bioactive glass support has large surface area of 365 to 194 m<2> / g and is suitable for serving as vectors of medicines and growth factors. The biological material can slowly release boron ions, can serve as a tissue repair material applied to bone and periodontium engineering, and can serve as vectors of medicines or genes.

The invention belongs to the scientific and technical field of oral medicine and oral health, and particularly relates to an oral health-care agent capable of clearing away heat and toxic materials, and a preparation method thereof. The oral health-care agent contains a food-grade heat-clearing and detoxicating prescription, an anti-ulcer agent, a caries-prevention agent, a cell adhesion moisturizer, a natural antibacterial and anti-inflammatory agent and an oral health-care agent, preferably, the preparation further contains a preservative, more preferably, the preparation further contains apreparation-acceptable safety carrier or excipients; and all the ingredients are scientifically prepared and optimized to obtain a group of safety and multi-effect compositions which not only can clear away heat and toxic materials and is antibacterial and anti-inflammatory, but also can prevent tooth and periodontium and other oral diseases, and then a convenient and practical oral health-care agent is prepared by adopting a mild technological method. The oral health-care agent capable of clearing away heat and toxic materials not only has medicine efficacy, but also has the safety of health-care food, and is convenient to use, good in efficacy and fast in effect.

The invention provides a DICM data based tooth jaw system finite element modeling method belonging to the field of dental biomechanical analysis methods. The method comprises the following steps: step1, identifying a DICM file, and establishing a tooth crude model and an alveolar bone crude model; step 2, establishing a tooth model, an alveolar bone overall model and an alveolar bone cellous model; step 3, taking out the tooth model from the alveolar bone overall model, and obtaining an alveolar bone model and a parodontium model; step 4, performing meshing on the tooth model, the parodontiummodel and the alveolar bone model; step 5, respectively endowing units belonging to teeth, alveolar bone and parodontium with physical attributes of corresponding tissues, and endowing the unit belonging to the alveolar bone with physical attributes of alveolar bone cortex; and step 6, identifying alveolar bone cellous internal units and endowing alveolar bone cellous physical attributes. According to the invention, a tooth jaw system finite element model can be rapidly and accurately established, so as to effectively improve the finite element analysis efficiency of the dental biomechanicalproblem.

The invention provides a dental brace type automatic toothbrush, which comprises a handle and a U-shaped framework, the U-shaped framework is connected with the front end of the handle, and is designed according to the human periodontium, the U-shaped framework comprises an upper side, a lower side, a left side and a right side, the lower side is opposite to the upper side, the right side is opposite to the left side, a plurality of movable blocks which can move along the track of the U-shaped framework are mounted on the left side and / or the right side, and a brushing layer for brushing teeth is arranged on the surface of each movable block, which is opposite from the U-shaped framework. The brushing layers of the movable blocks can automatically reciprocate to repetitively brush teeth, and compared with the prior art, the dental brace type automatic toothbrush is highly efficient, and can quickly clean up teeth.

The present invention relates to one kind of oral cavity and tooth cleaning article prepared with musk, cattail pollen, safflower, dahurian angelica root, astragalus root and other 11 kinds of Chinese medicinal materials. It can inhibit exogenous bacteria, inhibit tartar, improve tooth state, regulate microecological balance of periodontium, prevent caries and other dental diseases and relieve toothache.

The invention discloses a decellularized tilapia skin biomimetic substrate for soft tissue restoration as well as a preparation method and application thereof, and belongs to the field of a medical material. The decellularized tilapia skin biomimetic substrate is obtained by using the tilapia skin as raw materials through special treatment. A preparation method of the decellularized tilapia skin biomimetic substrate for soft tissue restoration comprises the process steps of raw material pretreatment, coarse finishing, decellularization, refinishing, storage liquid pretreatment, shaping and thelike. The decellularized tilapia skin biomimetic substrate for soft tissue restoration prepared by the method has the advantages that the network structure is complete; the flexibility is good; the substrate belongs to a low-immunogenicity biomimetic extracellular substrate stent material, has good biological function and physical performance, and can be used for restoration of various soft tissues such as burn and scald wound surfaces, ulceration wound surface, hernia repair, duramater reparation, urethra / bladder / pelvic floor reconstruction, periodontium restoration and mucosal tissue restoration.

The invention discloses chewable tables for oral cavities as well as a preparation method and an application thereof. Each chewable table comprises 0.5%-20% of drynaria total flavonoids, 5-50% of tea polyphenol and the balance of pharmaceutically acceptable carrier in percentage by mass. The preparation method of the chewable tables comprises the following steps of: crushing, sieving, mixing, pelleting, drying, pressing and packaging the 0.5%-20% of drynaria total flavonoids, the 5-50% of tea polyphenol and the balance of filler, corrigent, wetting agent, binding agent and lubricating agent; and as for the application, the chewable tables for oral cavity nursing are put in a mouth and chewed, and then the mouth is rinsed with clear water. As the tea polyphenol has good health care and treatment effect on oral cavity inflammation and oropharynx inflammation and the drynaria total flavonoids has a promotion effect on the repair, regeneration and rebuilding of periodontium, the chewable tables can be used for promoting the health of the oral cavities by adding the drynaria total flavonoids and the tea polyphenol.

The invention discloses an optimization method of an invisible dental appliance. The optimization scheme of the invisible dental appliance is reasonable; modelling is indirectly performed through simulating the tooth moving process by finite element software, so that a continuous invisible appliance model which conforms to the actual shape is established, and the continuous invisible appliance model is accurately assembled in a dental model; the integrated effect of an invisible correcting technology to dentition can be researched, and the optimization scheme is applied based on set constraintconditions and a nonlinear finite element analysis method, so that the simulation authenticity of the invisible appliance model is guaranteed; the stressing situation of periodontium and the invisible appliance is analyzed and optimized, the correcting force exerting region is controlled, the stress distribution of anchorage teeth is reduced, counter-acting force is dispersed through balancing force acting on the appliance, the mechanical anchorage consumption is educed, optimal correcting force is exerted, the reconstruction of the periodontium is effectively promoted, ideal moving of the teeth is produced, and the best correcting effect is achieved.

A video capable electric toothbrush for proper periodontium prophylaxis having a rotating bristle assembly configured to rotate in multiple directions so as to implement a brushing technique having the brush rotate in a direction from the gum towards the tooth by use of a switch, and regardless of the specific tooth or teeth being brushed, the electric toothbrush is configured to brush along the gingival margin towards the tooth crown. The video capability allows a user to see and target brushing along the gingival margin, and recognize areas with high debris quantity requiring additional attention.

The invention belongs to the technical field of biomedical engineering, in particular to the technical field of preparation of damaged-periodontium repair materials, and discloses a periodontium regeneration and repair membrane and a preparation method thereof. The periodontium regeneration and repair membrane is of a double-layer multihole meshed structure, and is prepared from polyoxyethylene, polyvinyl alcohol, type-I collagen, hydroxyapatite and modified sodium alginate. The periodontium regeneration membrane is low in immunogenicity and high in biocompatibility and induced repair capacity, and has an obvious promoting effect on regeneration of damaged periodontiums.

The invention discloses a toothbrush with ball point bristle and the preparing process, the ball point bristle comprising brush body and bristle, the brush body comprising brush holder and brush head, the base of the bristle is fixed in the brush head in cluster, the front end of the bristle is in ball point shape. The process for preparing the toothbrush comprises fixing the bristle on the brush head of the formed brush body, shaping bristle, heating the front end of the bristle under temperature of 280-300 Deg C for 2- 3 seconds and the front end becoming ball point shape. The dirt-removing ability of the ball point bristle toothbrush is strong and thorough, generating no harm to gingive, tooth and periodontal tissue, and it is smooth and comfortable when using it.

The invention provides an inductive agent for regeneration of periodontium tissue of temperature sensitivity, which is a temperature sensitivity hydrogel composite body taking chitosan, chitosan quaternary ammonium and Alpha, Beta-phosphate as carriers, and the carriers are loaded with plasmids containing bone tissue growth factor coding genes. The invention also provides a preparation method forthe regeneration of periodontium tissue of the temperature sensitivity. In the invention, the composite body is planted into a body, target DNA directly transfects target cells and continuously expresses coded growth factors, rebuilds and recovers the growth activity of osteoblast; along with the gradual degradation and absorption of biological support materials, tissues with the original specialstate and function are formed, so that the purpose of alveolar bone regeneration and function rebuilding are achieved. In the invention, the defect that the half-life period is short due to the direct application of an exogenous growth factor is overcome, and the barrier of immunological rejection as the exogenous cells are planted into the body is broken through, therefore, the clinical application value and the clinical application potential are exact.

The invention discloses a biological scaffold material for periodontium and a preparation method of the biological scaffold material, which belongs to the technical field of biologic tissue engineering scaffolds. The biological scaffold material is prepared from a shell solution and a core solution by using a coaxial electrostatic spinning method, wherein the shell solution and the core solution are prepared by respectively dissolving and subsequently uniformly mixing carrier compound nano microspheres containing one gene plasmid into a degradable organic macromolecule solvent. The biological scaffold material which is provided with a core-shell structure and is prepared by using the coaxial electrostatic spinning method is simple in process, easy to operate, low in cost and can be applied to non-virus gene therapy in tissue engineering mediation.

The invention discloses a preparation method of chitosan asymetric membrane for leading periodontium to be regenerated, comprising the steps of: preparing basal plasmamembrane of the chitosan by means of forming a salivating membrane; preparing chitosan / polyvinyl alcohol spinning solution A and hydroxylapatite / chitosan / alcohol spinning solution B; filling the spinning solution A or the spinning solution B into an injector; and eclectically spinning a layer of nonwoven membrane with porous structure on the basal plasmamembrane of the chitosan by means of spinning anelectric. The chitosan asymetric membrane can provide more structural space for cell growth and good microenvironment for cell survival, and can actively lead the periodontium to be regenerated (the regeneration comprises agglutination, differentiation, proliferation and secretion of extracellular matrix). Meanwhile, the basal plasmamembrane of the chitosan also can be used as a barrier membrane to stop the ingeneration of fibroblast, and is good for the osteoblast to grow into a defect area of the periodontium. The preparation method is simple, has low cost and good tissue compatibility, and can be adsorbed in human body.

A system for treating conditions of the periodontium, such as gingivitis and periodontitis, includes an Ayurvedic medicinal solution and an applicator for delivering the solution to the periodontium. The Ayurvedic medicinal solution utilizes herbal extracts to break-down bacteria which can inflame gum tissue. In one embodiment, the solution comprises approximately 1 gram of triphala extract for every 10 ml of glycerine. In another embodiment, the solution comprises approximately 1 gram of amla extract for every 10 ml of glycerine. The applicator for delivering the solution to the periodontium may either be in the form of a cotton swab-type wand, a pipette or a spray dispenser.

The invention discloses a traditional Chinese medicine based narcotic drug used for a tooth extraction operation and a preparation method thereof. The traditional Chinese medicine based narcotic drug comprises the raw medicines as follows: flos rhododendri, rubia cordifolia, flos daturae, pentapetes phoeniceam, glaucescent fissistigma root, carbo of typhae pollen, membrana follicularis ovi, cutch, alangium chinense harms, illicium verum, stellaria media, honeysuckle, herb of pedunculoside and radix angelicae. The traditional Chinese medicine based narcotic drug provided by the invention is prepared based on traditional Chinese theory of traditional Chinese medicine, has the advantages of being free of toxic and side effect, good in effects on relieving pain and stopping bleeding, fast to come into effect and low in cost, does not need injection when in use; when in use, dental tweezers are operated to clamp a cotton ball to drop or apply the liquid medicine into a periodontal pocket of a tooth to be extracted; when the periodontium has no pain, the tooth extraction operation can be carried out; therefore, the feared state of mind of a patient, especially a child and the patient fearful of giving an injection or the patient fainting on acupuncture, can be quelled.

The present invention relates to an injectable system combining a hydrogel, a bioceramic and a degradable matrix that provides for sustained drug delivery and structural support to recovering tissue, such as bone and the periodontium.

The invention discloses a method of preparing a composite biotinylated chitosan film and application of the method in peridontal tissue regeneration. The composite biotinylated chitosan film comprises recombinant human bone forming protein -2(rhBMP2) chitosan microspheres and basicfibroblast growth factor (bFGF) chitosan microspheres; the rhBMP2 and the bFGF are wrapped by the chitosan microspheres; the rhBMP2 and bFGF chitosan microspheres are wrapped in the composite biotinylated chitosan film, or the rhBMP2 chitosan microspheres or the bFGF chitosan microspheres are wrapped in the composite biotinylated chitosan film. The invention is capable of controlling to release the rhBMP2 and the bFGF for a long time, making sure the growth factors better display their function in regeneration of peridontal tissues, so as to realize total regeneration of the peridontal tissues and recovery of the periodontal functions.

The invention aims to provide electrostatic spinning fiber periodontal tissue regeneration material capable of carrying medicine. The electrostatic spinning fiber periodontal tissue regeneration material capable of carrying medicine comprises, by weight percentage, 50-99% of polylactic acid and 1-50% of calcium alginate, wherein the polylactic acid serves as main support material, the calcium alginate serves as adjusting material for adjusting material degradation rate and improving polylactic acid degradation rate, the weight-average molecular weight of the polylactic acid is 1*10<4>-9*10<7>g / mol, and the molecular weight of the calcium alginate is 1*10<4>-9*10<6>g / mol. The electrostatic spinning fiber periodontal tissue regeneration material capable of carrying medicine has the advantages that the electrostatic spinning fiber periodontal tissue regeneration material is novel medical periodontal tissue regeneration material capable of carrying medicine, the structure features of the electrostatic spinning fiber periodontal tissue regeneration material are similar to those of pericementum fibers, material components are beneficial for bone tissue forming, and the electrostatic spinning fiber periodontal tissue regeneration material can be used to promote tissue regeneration after periodontal surgery and increase surgery curative effect.

The invention discloses a traditional Chinese medicine composition with effects of resisting periodontitis and protecting periodontium and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 2-5 parts of honeysuckle flowers, 1-5 parts of herba violae, 1-5 parts of radix scutellariae, 2-5 parts of herba taraxaci, 1-5 parts of flos chrysanthemi indici, 1-5 parts of kudzuvine roots, 1-5 parts of radix salvia miltiorrhiza, 1-5 parts of radix angelicae and 1-5 parts of wrinkled gianthyssop herb. The traditional Chinese medicine composition with the effect of treating diabetic periodontitis is scientific and reasonable in proportion; animal model experiment results show that the traditional Chinese medicine composition has the effects of significantly relieving the inflammatory reaction action, lowering the blood glucose and effectively protecting the periodontium, can be used for preparing drugs or healthcare products or daily necessities for preventing and treating the periodontitis and is suitable for patients suffering from the periodontitis, especially the patients suffering from the periodontitis and diabetes; in addition, no obvious toxic or side effect is found in the experiment process, and the traditional Chinese medicine composition is good in safety, can be conveniently prepared into multiple clinical dosage forms and is convenient to take.

The invention discloses a digitization panorama dental X line imager used for generating a digital image comprising full mouth teeth and a periodontium. The digitization panorama dental X line imager comprises an X line exposure setting panel, an X line generator, an X line receiver, a C-shaped arm, a storage platform, a support device, an X line exposure script, a USB(power supply) interface and a power supply, wherein the X line exposure setting panel is used for setting an X line exposure parameter, and the X line generator is controlled to generate an X line; the X line passes through the storage platform so as to be received by the X line generator, and the X line generator receives the X line and then outputs a digital signal which is uploaded to a computer through the USB interface; the two ends of the C-shaped arm are respectively connected with the X line generator and the X line receiver, and the X line exposure setting panel and the X line generator are arranged on the same side of the C-shaped arm; the support device is connected with the C-shaped arm, the storage platform, the X line exposure script, the USB interface and the power supply; and the power supply provides the required voltage for the whole X line imager. The digitization panorama dental X line imager provided by the invention has the advantages of being pollution-free, small in radiation dosage, high in imaging speed, simple in operation, and rich in digital image level.

The invention relates to the technical field of oral products, and discloses an oral product containing hyaluronic acid and a preparation method of the oral product. A composition containing the hyaluronic acid comprises a hyaluronic acid composition and fluoride, wherein the hyaluronic acid composition comprises micromolecular hyaluronic acid, medium molecular hyaluronic acid and macromolecular hyaluronic acid, or comprises micromolecular hyarolunate, medium molecular hyaluronate and macromolecular hyaluronate. The prepared oral product is toothpaste, mouthwash, gel, tooth powder or oral spray. According to the invention, fluorine ions released by the fluoride can be attached to a hyaluronic acid film and are slowly released into the tooth surface through the hyaluronic acid film, the anti-caries and remineralization effects of the fluorine ions are gradually achieved, the action time of the fluorine ions is prolonged, and the action effect is enhanced; and meanwhile, the transfer and absorption of the fluorine ions by periodontal tissues and oral mucosa can be avoided, and the irritation is reduced.

The invention relates to an oral cavity scanning device and method based on high-frequency ultrasonic. The device is single-vibration-unit ultrasonic probe or a single-vibration-unit ultrasonic probefixed to a mechanical arm, wherein the single-vibration-unit ultrasonic probe is provided with a position sensor and utilizes a gel tooth socket made of ultrasonic gel. The method includes the steps of firstly, using the oral cavity scanning device to scan teeth and periodontal tissue face by face; secondly, using an ultrasonic image segmenting and rebuilding technology to segment and rebuild a target tooth section. The oral cavity scanning device and method has the advantages that tooth and periodontal tissue rebuilding can be achieved in a fast, efficient and zero radiation manner, image acquisition speed and accuracy in oral medicine are increased greatly, and the device and method is high in clinical practical value.

The invention relates to a preparation method of engineering periodontium, which is used for reconstruction of periodontium. The periodontium comprises periodontal ligament stem cells and an extracellular matrix secreted and synthesized by the periodontal ligament stem cells. The periodontal ligament stem cells are subjected to amplification culture to form multi-layered periodontal ligament stem cell assemblies, and then the periodontal ligament stem cell assemblies are arranged layer by layer and molded to form the engineering periodontium. The periodontium can form a new dentinal structure in the human body, so that periodontal defects can be repaired. The periodontium is simple in preparation, good in plasticity, moderate in cell density, abundant in extracellular matrix content, free of support material, and short in in-vitro culture time.