Traditional Chinese medicine based narcotic drug used for tooth extraction operation and preparation method thereof
A technology of traditional Chinese medicine anesthesia and medicine, which is applied in the direction of anesthetics, drug combinations, and medical formulas, etc., can solve problems such as troublesome work of dentists, allergic reactions, bleeding, etc., and achieve the effect of eliminating fear, quick results, and low cost
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[0032] Wherein, when the dosage form of the traditional Chinese medicine anesthetic is a tincture, the preparation method includes the following steps:
[0033] In the first step, the raw medicinal materials are mixed according to the proportions, and are pulverized into a mixture of micron-sized particles with a volume average particle diameter of 0.1-10 μm and nano-sized particles with a volume average particle diameter of less than 0.1 μm in an ultrafine pulverizer. Powder, the powder yield of the mixed powder is at least 90%;
[0034] In the second step, the mixed powder obtained in the first step is added with 4 to 8 times the mass of the mixed powder with ethanol with an alcohol concentration of 85%-95%, stirred and dissolved to obtain an ethanol solution, and the ethanol solution is Let stand for 30-60 hours under the condition of 4℃~6℃, use the percolation method to slowly percolate at the speed of 1~2ml per minute, collect the percolate, concentrate and dry, and put it in ...
Embodiment 1
[0037] Example 1: Tincture 1 prepared by the present invention
[0038] Take mutton flower 12g, madder charcoal 26g, yangjinhua 23g, midday flower 17g, black bone vine 21g, puhuang charcoal 17g, phoenix clothing 22g, catechu 11g, star anise maple root 18g, star anise 28g, chickweed 23g, 27g honeysuckle, 16g lipstick and 31g angelica;
[0039] The preparation method includes the following steps:
[0040] In the first step, the above-mentioned raw materials are mixed in proportion and put into an ultrafine pulverizer to pulverize into a mixed powder composed of micron particles with a volume average particle diameter of 2 μm and nano particles with a volume average particle diameter of less than 0.1 μm. The powder yield rate of the mixed powder is at least 90%;
[0041] In the second step, add ethanol with an alcohol concentration of 90%, which is 6 times the mass of the mixed powder, to the mixed powder obtained in the first step, stir and dissolve to obtain an ethanol solution, and t...
Embodiment 2
[0043] Example 2 Tincture 2 prepared by the present invention
[0044] Take yanghua 10g, madder charcoal 23g, yangjinhua 17g, noon flower 15g, black bone vine 24g, cattail charcoal 19g, phoenix coat 24g, catechin 13g, star anise maple root 21g, star anise 26g, chickweed 21g, 25g of honeysuckle, 18g of lipstick and 27g of Angelica dahurica;
[0045] The preparation method includes the following steps:
[0046] In the first step, the above-mentioned raw materials are mixed in proportion and put into an ultrafine pulverizer to pulverize into a mixed powder composed of micron particles with a volume average particle diameter of 1 μm and nano particles with a volume average particle diameter of less than 0.1 μm. The powder yield rate of the mixed powder is at least 90%;
[0047] The second step is to add ethanol with an alcohol concentration of 85% to the mixed powder obtained in the first step, which is 8 times the mass of the mixed powder, and stir to dissolve to obtain an ethanol solut...
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