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Oral product containing hyaluronic acid and preparation method of oral product

A technology of hyaluronic acid and oral products, which is applied in the field of oral products and can solve the problems of strong oral astringency and poor mouthfeel

Inactive Publication Date: 2021-04-09
CHONGQING DENCARE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The present invention intends to provide an oral product containing hyaluronic acid and a preparation method thereof, so as to solve the problems of strong astringency and poor mouthfeel of oral products in the prior art when fluoride is used to prepare dental caries-resistant oral products

Method used

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  • Oral product containing hyaluronic acid and preparation method of oral product
  • Oral product containing hyaluronic acid and preparation method of oral product
  • Oral product containing hyaluronic acid and preparation method of oral product

Examples

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Embodiment 1

[0035] Take embodiment 1 as example to describe the preparation method of mouthwash in detail, comprising the steps:

[0036] S1: Stir water, 5 g of glycerin, 13 g of sorbitol, and 1.2 g of poloxamer evenly, then add 0.5 g of sodium saccharin, and a sodium hyaluronate composition (the sodium hyaluronate composition in this embodiment is a small molecular weight transparent Sodium hyaluronate, medium molecular weight sodium hyaluronate, large molecular weight sodium hyaluronate mixed with equal volume ratio) 0.01g, stannous fluoride 0.11g, stannous chloride 0.5g, mix well, add methyl paraben 0.1g Stir to form a water phase;

[0037] S2: Add 0.5 g of mint essence and mix evenly, slowly add the water phase during the stirring process, filter and pack, and the mouthwash is prepared.

[0038] Efficacy experiments were carried out on the mouthwashes prepared in the above-mentioned examples and comparative examples to verify the efficacy experiments, including mouthfeel and stabilit...

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Abstract

The invention relates to the technical field of oral products, and discloses an oral product containing hyaluronic acid and a preparation method of the oral product. A composition containing the hyaluronic acid comprises a hyaluronic acid composition and fluoride, wherein the hyaluronic acid composition comprises micromolecular hyaluronic acid, medium molecular hyaluronic acid and macromolecular hyaluronic acid, or comprises micromolecular hyarolunate, medium molecular hyaluronate and macromolecular hyaluronate. The prepared oral product is toothpaste, mouthwash, gel, tooth powder or oral spray. According to the invention, fluorine ions released by the fluoride can be attached to a hyaluronic acid film and are slowly released into the tooth surface through the hyaluronic acid film, the anti-caries and remineralization effects of the fluorine ions are gradually achieved, the action time of the fluorine ions is prolonged, and the action effect is enhanced; and meanwhile, the transfer and absorption of the fluorine ions by periodontal tissues and oral mucosa can be avoided, and the irritation is reduced.

Description

technical field [0001] The invention relates to the technical field of oral products, in particular to a hyaluronic acid-containing oral product and a preparation method thereof. Background technique [0002] Dental caries is a progressive lesion of dental hard tissue caused by the complex effects of various factors in the oral cavity. It is manifested in the demineralization of inorganic matter and the decomposition of organic matter. With the development of the disease, it changes from color change to the formation of substantial lesions. Dental caries is a bacterial disease, so it can be secondary to pulpitis and periodontitis, and can even cause alveolar bone and jaw inflammation. The secondary infection of dental caries can form lesions, causing or adding to other diseases of the body such as arthritis, pericarditis, chronic kidney disease and various eye diseases. Therefore, prevention of dental caries has attracted more and more attention. [0003] Fluorine is one of...

Claims

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Application Information

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IPC IPC(8): A61K8/73A61K8/21A61K8/24A61Q11/00A61P1/02
CPCA61K8/735A61K8/21A61K8/24A61Q11/00A61P1/02A61K2800/5922
Inventor 张红陈凤张旻邓全富舒盈盈宫敬禹邓嵘
Owner CHONGQING DENCARE CORP
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