32 results about "MI - Myocardial infarction" patented technology

The invention relates to substituted triazine phenyl urea derivatives and application of the derivatives used as protein kinases, especially as Raf-1 inhibitors. The compounds provided by the invention can be used for treating various disorders and diseases, especially the protein-kinase-related diseases such as cancers, miocardial infarction, cerebral thrombosis, anaemia, hepatitis C (HCV) and other diseases.

The invention discloses a rapid immunofluorescence quantitative detection kit for multi-indicator detection of myocardial infarction. The rapid immunofluorescence quantitative detection kit for multi-indicator detection of myocardial infarction includes a nitrocellulose membrane, and one end of the nitrocellulose membrane is provided with The sample pad is provided with a water-absorbing pad at the other end of the nitrocellulose membrane, and the area between the water-absorbing pad and the sample pad of the nitrocellulose membrane is respectively coated with anti-troponin I, myoglobin, CK- MB antibody and internal quality control antibody. The invention utilizes the fluorescence characteristics of fluorescent particles with different diameters, combines chemical cross-linking labeling technology and immunochromatography technology, and realizes immunofluorescence quantitative detection on the basis of optimizing each component of the test strip. Compared with the conventional colloidal gold immunochromatography method, the present invention has the advantages of good labeling stability, low non-specificity, high sensitivity, small cross-interference and accurate quantification.

The invention belongs to the medication technical field, which discloses the medicine and the preparation method for treating the coronary heart disease and miocardial infarction. The medicine is mainly prepared from ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali and Chinese angelica, or ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali, Chinese angelica, cassia twig and liquorice, or ginseng root, dwarf lilyturf tuber, Chinese magnoliavine fruit, radix astragali, Chinese angelica, cassia twig, liquorice, danshen root, red peony root, radix notoginseng and safflower, according to certain ratios of weights. The invention can be made to any type of medicament that can be accepted by the clinic or pharmacology, which is the good quality oral preparation. The medicine has effects of Qi-replenishing, Yin-nourishing and pulse-invigorating and blood circulation activating to dissipate blood stasis and lipid lowing, which can be used to curing the chest distress, hard breathe, heart-throb, angina and arrhythmia caused by coronary heart disease and miocardial infarction, the recovery period of the cerebral thrombosis and the sequelae of the cerebral thrombosis, the effects are obvious.

The invention discloses a potassium magnesium aspartate sterile powder injection and a method for preparing the same. The method is as follows: polyaspartate, magnesium oxide and potassium Hydroxide are prepared into a solution according to a certain method to obtain a liquid medicine, the liquid medicine is subject to reduced-pressure vacuum drying, solvent crystallization or spray drying, and is prepared into sterile packaged products for injection. The potassium magnesium aspartate sterile powder injection of the invention has the advantages of rapid redissolution, excellent stability, simple process, low production cost, suitability for industrial production, etc. the potassium magnesium aspartate sterile powder injection is mainly used for supplementing electrolyte, and can also be used for the treatment of hypokalemia and arrhythmia (mainly ventricular arrhythmia) caused by digitalism, and for the adjuvant treatment of myocarditis sequela, congestive heart failure, and miocardial infarction.

The invention discloses a conductive micro-needle patch integrated with myocardial cells derived from induced pluripotent stem cells and a preparation method for the conductive micro-needle patch andapplication of the conductive micro-needle patch. The patch consists of a micro-needle array layer, carbon nanotube layers and a hydrogel scaffold layer which are sequentially superimposed, wherein the carbon nanotube layers are integrated with the myocardial cells derived from the induced pluripotent stem cells and are arranged in parallel. A hydrogel prepolymer solution fills pores of a templateand is solidified to form the micro-needle array layer, then the carbon nanotubes layers arranged in parallel are deposited, and finally, the hydrogel prepolymer solution is filled again and is solidified, and the conductive micro-needle patch is obtained after the template is stripped; and the conductive micro-needle patch is used for subsequent differentiation culture of the induced pluripotentstem cells. The patch provided by the invention has a simple preparation method, is not restricted by cell sources, and is expected to become an effective therapeutic carrier for treatment of myocardial infarction.

The invention belongs to the technical field of medicine and discloses a pharmaceutical composition for treating cardiovascular and cerebrovascular diseases. The pharmaceutical composition is prepared by ginsenoside and carithamine as main ingredients and can be prepared into pharmaceutically or clinically acceptable dosage forms. The pharmaceutical composition has functions of expanding blood vessels of brain, reducing cerebral vascular resistance, increasing cerebral blood flow, obviously minimizing infarct area of brain tissues, obviously lightening behavior disorders caused by brain tissue necrosis, and the like, and can be used for preparing medicaments for treating diseases such as cerebral circulation insufficiency, cerebral thrombosis, cerebral embolism, brain blood vessels spasm, brain insufficiency, senile dementia, Parkinsonism, cerebral apoplexy, hypertension, hyperlipemia, arteriosclerosis, coronary heart disease, angina pectoris, miocardial infarction, etc.

The invention discloses a medicine used for curing the diseases such as coronary heart disease, angina, miocardial infarction, retinal artery or vein occlusion and sudden deafness, etc. and a preparation method thereof. The invention aims at making up the deficiency of the prior art and provides a puerarin sustained-release pill preparation. In the constituents adopted by the prior art, the puerarin sustained-release pill related by the invention utilizes hydrophilic framework material and hydrophobic framework material as stroma and is added with stabilizing agent vitamin C, so as to effectively overcome the defects of the prior art and ensure that the medicaments do not have apparent change relating to the material contents within the valid storing period; furthermore, the puerarin sustained-release pill has the advantages of enough medicine release, controllable medicine releasing time, few times needed by the patient to take the medicine, long time for taking effect and high bioavailability, and is suitable for clinic and family.

The invention discloses a preparation method of a traditional Chinese medicine for treating myocardial infarction. The traditional Chinese medicine is characterized by being prepared from the following raw materials by weight: 8 grams of raw cattail pollen, 8 grams of red sage root, 8 grams of longstamen onion bulb, 8 grams of snakegourd fruit, 8 grams of cassia twig, 8 grams of pinellia ternate, 8 grams of peach seed, 8 grams of safflower, 8 grams of flying squirrel feces, 8 grams of pseudo-ginseng, 3 grams of amber, and 500 grams of water. The preparation and application method comprises the following steps: soaking the raw cattail pollen, red sage root, longstamen onion bulb, snakegourd fruit, cassia twig, pinellia ternate, peach seed, safflower, flying squirrel feces, pseudo-ginseng, and amber in water for 30 minutes, placing the raw materials into a container such as a marmite, a ceramic pot or a crock, decocting for two times, and finally emerging the two decoctions, wherein the total volume of the emerged decoction is 150 to 200 mL; drinking the decoction with a warm temperature, drinking one decoction for a day, and drinking the decoction before breakfast and dinner. People who have the difficulty in taking the decoction can drink the decoction for several times, and a treatment comprises 5 decoctions.

The present invention relates to traditional Chinese medicine, in particular to a black fungus and purple perilla seed composite capsule having effects of lowering blood fat, preventing thrombosis, myocardial infarction and cerebral infarction, improving organism immune function and preventing against aging. The black fungus and purple perilla seed composite capsule is characterized by consisting of the following raw materials (parts by weight): 3.6-5.1 parts of black fungus, 4-5 parts of salisburia adiantifolia, 2.5-4.0 parts of purple perilla seeds, 1.5-3.0 parts of radix puerariae, 2.5-4.0 parts of rhizoma polygonati and 2.5-4.0 parts of cordate houttuynia. The composite capsule is prepared by the following steps: drying the black fungus and crushing the dried black fungus into black fungus powder which can sift through 100 mesh sieves for next steps, then washing and cleaning the salisburia adiantifolia, purple perilla seeds, radix puerariae, rhizoma polygonati and cordate houttuynia, adding water to boiling twice with two hours for each time, merging the boiled liquids, filtrating, concentrating the filtrate into a thick paste and drying at a temperature of 80 DEG C, spraying the dried paste into a powder and sifting through 100 mesh sieves, then mixing the black fungus powder and the above traditional Chinese medicine extract powder evenly, and packaging the mixed powders into capsules. The advantages of the silver fungus powder composite capsule are that the composite capsule has simple technology and convenient operation, is suitable for industrial production, has effects of lowering blood fat, preventing thrombosis, myocardial infarction and cerebral infarction, improving organism immune function and preventing against aging, and has a markedly effective rate of more than 96%, an effective rate of more than 89% and a cure rate of 83%.

The invention relates to a traditional Chinese medicine, and in particular to a black fungus and gingko compound capsule with functions of lowering blood fat, preventing thrombosis, myocardial infarction and cerebral infarction, improving immunity and resisting aging. The compound capsule is characterized by being prepared from, by weight, 4.6-6.1 parts of black fungus, 7-8 parts of ginkgo, 4.5-6 parts of perilla seed, 3.5-5.0 parts of the root of kudzu vine, 4.5-6.0 parts of rhizoma polygonati and 4.5-6.0 parts of Houttuynia. A preparation method is as below: drying and crushing black fungus, sieving through a 100-mesh sieve to obtain a black fungus powder for standby; cleaning ginkgo, perilla seed, the root of kudzu vine, rhizoma polygonati and Houttuynia; adding water and decocting two times for 2 hours each time; mixing the two decoction, filtering, concentrating the filtrate into a thick paste and drying at 80 DEG C, spraying the powder through a 100-mesh sieve; and evenly mixing the black fungus powder with the Chinese herbal medicine extracted powder and filling capsules with the mixture. The invention has the advantages of simple technology, simple operation and applicability to industrialized production. The black fungus and gingko compound capsule has the functions of lowering blood fat, preventing thrombosis, myocardial infarction and cerebral infarction, improving immunity and resisting aging, reaches significant efficiency of higher than 96%, effective rate of 89% and cure rate of 83%.

The invention discloses health-care vinegar, a brewing method and application in preventing cardiovascular diseases thereof. The method comprises the following steps: (1) removing peel of 6 to 7 weight percent of fresh kudzuvine root after the fresh kudzuvine root is cleaned, adding water or medicinal extract for homogenating, and regulating the quality concentration of starch to be over 10 percent; (2) heating the homogenated fresh kudzuvine root for 10 to 20 minutes at the temperature of between 120 and 125 DEG C; (3) adding rhizopus, activated dried yeast, aroma-producing yeast and lactic acid bacteria into the sterilized mixture to ferment distilled wort, adding 10 percent lactic acid bacteria seed fermentation broth into the mixture when the alcohol content is detected to be between 6 and 8 percent, leading the fermentation temperature to be between 26 and 34 DEG C, adding edible salt into the mixture when the acidity of the fermentation broth is not changed, and stopping alcoholic fermentation; and (4) ageing the fermented acid solution for over 15 days at the temperature of between 12 and 20 DEG C, and filtering the solution to obtain the health-care vinegar. The health-care vinegar obtained by the brewing method can effectively inhibit CPK activity caused by myocardial ischemia and myocardial infarction, can reduce ET content (P is less than 0.05), has inhibition effect on LDH, can be used in preparation of medicament for preventing cardiovascular diseases, and has wide application prospect.