The invention provides a moxa leaf moxa preparation and a preparation thereof, wherein the moxa leaf moxa preparation is prepared from the following ingredients: moxa leaf, musk, actinolite, piper longum, embelia laeta, golden clematis, clove, cassia bark, calamus, pomegranate seed, anemone rivularis, codonopsis convolvulacea, mastic, stichopus japonicus, cyrtomium fortune, cornua cervi pantotrichum, rhodiola crenulata, black aoud, amber, jade, Chinese caterpillar fungus, rhizoma zingiberis, incarvillea compacta, myrobalan, rhododendron thymifolium maxim, mirabilis himalaica, perilla nankinensis, tenuifolia, cortex acanthopanacis, drynaria rhizome, herba siegesbeckiae, myrrh and albizia julibrissin. The preparation method of the moxa preparation is as follows: grinding all the other raw materials except for the moxa leaf and the musk, and steaming by mixing with the moxa leaf for more than 81 hours; smashing the moxa leaf absorbing medicine, and kneading into the moxa preparation after mixing with the musk; the moxa preparation not only has curative effects on a plurality of appeared-symptom diseases, but also can prevent diseases and improve the physical quality and the resistance to disease, and meanwhile, the preparation method has the advantages of high drug utilization and low cost.