The invention discloses mask disinfection equipment, and relates to the field of mask disinfection. The mask disinfection equipment comprises a work box, a moving mechanism, a supporting mechanism, aspraying mechanism, an ultraviolet mechanism and a drying mechanism, wherein the work box is arranged on the ground, the moving mechanism is arranged on the inner side of the work box, the moving mechanism is provided with a sliding table, the supporting mechanism is arranged on the sliding table, the liquid conveying end of the spraying mechanism is arranged on the working box, the working end ofthe spraying mechanism is arranged in the working box, the ultraviolet mechanism is arranged on the inner side wall of the working box, and the drying mechanism is arranged in the working box. The mask disinfection equipment is provided with the supporting mechanism, through the work of a second motor, a push plate pushes open masks through groove in a carrying plate, so that the contact area ofthe masks is larger, and disinfection is more comprehensive.