199 results about "2-hydroxybenzaldehyde" patented technology

The invention discloses a visible and reversible fluorescent probe which comprises a cyanine fluorescent group and a benzothiazole group, and the general formula of the probe is shown in the description. The preparation method of the reversible fluorescent probe comprises the following steps: (1) dropwise adding phosphorus oxychloride into salicylaldehyde and paraformaldehyde for reaction, so as to obtain a product 1; (2) enabling the product 1 and hexamethylene-tetramine to react, so as to obtain a product 2; (3) enabling the product 2 and 2-aminobenzenethiol to react at the room temperature, so as to obtain a product 3; (4) enabling the product 3 and a compound 4 to react, so as to obtain the visible and reversible fluorescent probe. According to the ratiometric fluorescent probe provided by the invention, obvious color variation can be found out under natural light or an ultra-violet lamp, and the qualitative detection of sulfur dioxide gas can be implemented under natural light or a hand-held ultra-violet lamp, so that the operation is simple, high convenience and quickness are achieved, and the effect is remarkable; the fluorescent probe can effectively prevent interference from other impurities in samples, and is excellent in selectivity; in addition, the cumbersome pre-processing process of samples is avoided, so that the detection efficiency is high.

The invention discloses a new method to synthesize 2-[2-(3-methoxyphenyl)-ethyl] phenol(I). The new method is characterized in that the method takes salicylaldehyde as material to prepare 2-benzyloxy-benzyl chloride through benzyl protection, deoxidization and cl-substitution; 2- benzyloxy-benzyl chloride is turned to [[2-(benzyloxy) phenyl] methyl] diethyl phosphonate through Arbuzov reaction and then 1-benzyloxy-2-[2-(3-methoxyphenyl) ethylene] benzene is obtained through Witting-Hommer reaction; finally, 2-[2-(3-methoxyphenyl)-ethyl] phenol(I) is obtained through catalytic hydrogenation. The invention also discloses new intermediate compounds in the syntheticroute of synthesize 2-[2-(3- methoxyphenyl)-ethyl] phenol(I).

The invention belongs to the field of medicine, and especially relates to an amiodarone hydrochloride preparation method. The method takes 2-hydroxybenzaldehyde and 2-alkyl halohexoic acid ester as the raw materials to prepare 2-butylbenzofuran, 2-butylbenzofuran is taken as the raw material, and is subjected to the steps of friedel-crafts acylation, demethylation, iodination, etherification and salt forming to obtain the amiodarone hydrochloride. By employing the method, the raw materials have the advantages of low cost and easy acquisition, the process is simple, and 2-butylbenzofuran and amiodarone hydrochloride with high purity and high yield can be obtained, the cost is low, the waste water is little, and the method is suitable for industrial production.

The invention relates to a method for preparing single salicylaldehyde imine vanadium olefin polymerization catalyst and application of the catalyst in catalyzing ethylene polymerization. Under the catalyzing effect of formic acid, condensation reaction of the salicylaldehyde or derivatives of the salicylaldehyde and aniline or derivatives of the aniline is carried out in methanol solution, and skiff base is obtained. Under the condition of no water and no oxygen and under the effect of excess triethylamine, the single salicylaldehyde imine vanadium olefin polymerization catalyst of the invention is obtained by complexation reaction of the skiff base and vanadium trichloride. Under the effect of diethyl aluminium chloride, the catalyst of the invention can be used for catalyzing ethylene polymerization. The invention has the advantages of easy preparation, high catalyzing activity and good thermal stability.

The invention relates to a functional reactive dye for a zinc ion probe, and a preparation method and application thereof. The dye has a structural formula as described in the specification. The preparation method comprises the following steps: subjecting rhodamine B and hydrazine hydrate to a heating reflux reaction so as to obtain rhodamine B hydrazide; subjecting methyl p-aminobenzoate and hydrazine hydrate to a heating reflux reaction, dissolving a product in a solvent, adding salicylaldehyde drop by drop and then carrying out a heating reflux reaction so as to obtain salicylaldehyde-4-aminobenzoyl hydrazone; and dissolving cyanuric chloride in a solvent, adding an acid binding agent, adding rhodamine B hydrazide drop by drop at a temperature in a range of -5 to 5 DEG C, carrying out a reaction under stirring so as to obtain a concentration product, dissolving the concentration product in a solvent, adding the acid binding agent, adding salicylaldehyde-4-aminobenzoyl hydrazone drop by drop and carrying out a reflux reaction with temperature controlled so as to obtain the functional reactive dye. The functional reactive dye has good selectivity on zinc ions, is convenient to use in sewage treatment and exerts good usage effect.

The invention discloses an aggregation-induced emission-based copper ion detection probe and a preparation method and application thereof. The structure of the fluorescent probe is as shown in a formula I, and the fluorescent probe is prepared through formylating hydroxytetrstyrene as a raw material and forming triphenylethylene-based salicylaldehyde azine together with hydrazine hydrate. The probe is stable in optical property, high in copper ion detection sensitivity and low in lower detection limit, the detection limit is 30.9nM and the response range is 0.5-7.5muM; the probe is good in selectivity and free of response to cations such as a silver ion, a barium ion, a calcium ion, a lithium ion, a magnesium ion, an ammonium ion, a nickel ion, a zinc ion, a mercury ion, a cobalt ion and a lead ion; and the probe is simple in synthesis, mild in condition and high in yield. The fluorescent molecular probe has practical application value in the field of copper ion detection in biochemistry and environmental chemistry.

The invention discloses a molecular probe for detecting cyanide ions and a synthesis and application method thereof. The probe disclosed by the invention is obtained by performing condensation on 4-amino-1,-8-naphthalimide framework which is diazotized and salicylaldehyde or a derivative of the salicylaldehyde. Chromophore of the probe adopts a naphthalene imide azobenzene structure; a response group to the cyanide ions is a salicylaldehyde unit; an absorption peak of the independent probe in the solution is positioned at 407nm, and the solution is yellow; along with the adding of the cyanide ions, the absorbency at the 407nm wavelength is continuously decreased, the absorbency at the 497nm wavelength is continuously increased, and the color of the solution turns from yellow into red. Molecules of the probe are high in selectivity and sensitivity to the cyanide ions and high in response speed; the response range is 2-45mu mol.L<-1>; the detection limit is 0.4mu mol.L<-1>. The probe can be used for detecting the cyanide ions in water, soil and organisms.

The invention discloses a Schiff base zinc ion and magnesium ion fluorescent probe and a preparation method thereof. The preparation method comprises the following steps: by adopting absolute ethyl alcohol as a solvent, dissolving tetra-(diethylin)-salicylaldehyde in a reaction bottle, and heating to 70-80 DEG C; by adopting absolute ethyl alcohol as a solvent, after dissolving p-phenylenediamine, dropwise adding into the reaction bottle, and carrying out reflux reaction for 7-8 hours; and filtering and drying the mixed liquid after reaction to remove the solvent to obtain the Schiff base zinc ion and magnesium ion fluorescent probe. The method is simple and convenient and efficient to operate, and the needed intermediate is low in cost. The reaction process is easy to control, and the product is easy to separate, high in yield and high in purity. The fluorescent probe has a special identifying performance on zinc and magnesium ions, and has an application prospect in the aspects such as sensor technology, photochemistry and electroluminescent apparatuses.

The invention provides a salen-like and diketone-base dysprosium tetranuclear cluster compound type monomolecular magnetic material and a preparation method thereof and relate to a cluster compound and a preparation method thereof. The invention aims at solving the technical problem that the existing dysprosium tetranuclear cluster compound type monomolecular magnetic material has low effective revolving and inverting energy barrier. The molecular formula of the salen-like and diketone-base dysprosium tetranuclear cluster compound type monomolecular magnetic material is [Dy4(mu3-OH)2L2(acac)4].H2LCH3CN. The method comprises the following steps of: firstly, at a room temperature, dissolving 1,2-hexamethylene diamine salicylaldehyde and diacetone in an aprotic polar solvent, and adding organic base to obtain a mixture A; secondly, adding dysprosium chloride salt to a protonic polar solvent to obtain a mixture B; and thirdly, dripping the mixture B in the mixture A, then agitating, reacting, filtering, and settling filtrate for 14 days. The cluster compound is used in the fields of high density information storage, quantum computer and the like.

The invention provides a fluorescent probe for detecting hydrogen sulfide in cells, a method for preparing the fluorescent probe and application thereof. A chemical structural formula of the fluorescent probe is shown. Reaction can be carried out on 2,4-dinitrofluorobenzene and reaction products of 4-ethynylbenzonitrile and 4-bromine-2-hydroxybenzaldehyde to obtain the fluorescent probe. The hydrogen sulfide in solution or the cells or organisms can be detected by the fluorescent probe by the aid of fluorescence. The fluorescent probe, the method and the application have the advantages that the fluorescent probe can be obtained by means of chemical synthesis, synthesis processes are simple and feasible, raw materials are inexpensive and are easily available, and accordingly the fluorescentprobe is low in preparation cost; the fluorescent probe is high in specificity, and interference due to other components can be prevented in detection procedures; the fluorescent probe is short in response time, high in sensitivity and excellent in fluorescence emission spectral characteristic, and the hydrogen sulfide in the cells can be quickly and accurately detected by the fluorescent probe;the fluorescent probe has a broad application prospect in research on the influence of the hydrogen sulfide in the biological cells on physiological and pathological procedures.

The invention provides multifunctional chelating ion-exchange fibers. According to the invention, natural cotton fibers, fibrilia, natural wood fibers, natural bamboo fibers or natural grass fibers, or blend fibers of one selected from the group consisting of atural cotton fibers, fibrilia, natural wood fibers, natural bamboo fibers or natural grass fibers and one selected from the group consisting of polypropylene fibers, acrylic fibers, vinylon, terylene and spandex are used as a fiber based material; the fiber based material is dipped in amino-containing resin emulsion so as to prepare functional fibers whose surface is coated with tertiary amino-containing resin; the tertiary amine functional fibers sequentially react with 5-chloromethyl salicylaldehyde and thiosemicarbazide, and therefore, quaternary ammonium groups and salicylaldehyde thiosemicarbazone are introduced onto the functional fibers which become the multifunctional chelating ion-exchange fibers.

Deposition of a redox polymer of the poly-Me(R-Salen) type onto a conducting substrate by electrochemical polymerization is disclosed. Said polymerization occurs at a voltage applied between the substrate and a counter-electrode, both of which are submerged into the electrolyte. The electrolyte contains an organic solvent, compounds capable of dissolving in the solvent and forming electrochemically inactive ions at concentrations of no less than 0.01 mol/l within the range of potentials from −3.0 V to +1.5 V, and a metal complex poly-[Me(R-Salen)] dissolved at a concentration of no less than 5×10⁻⁵ mole/liter. Me is transition metal having at least two different degrees of oxidation, R is an electron-donating substituent, Salen is a residue of bis(salicylaldehyde)-ethylenediamine in Schiff' s base). Deposition of the redox occurs in the electrolyte where the cations of the compounds have a diameter larger than that of the electrolyte cations of energy storing device containing the electrode.

The invention discloses an in imidazo[1,5-a]pyridine-rhodamine salicylaldehyde copper ion ratio fluorescence probe and an application thereof. The probe is imidazo[1,5-a]pyridine substituted rhodamine salicylaldehyde, and the chemical structural formula of the probe is represented by formula (1). The fluorescence probe has unique fluorescence selectivity and high sensitivity on Cu<2+> in an ethanol solution, has strong resistance to interference of other ions, and has great application prospect.

The invention provides a preparation method of DL-lysine, which comprises the following steps: using lysine salt as a raw material and adding the lysine salt to an aqueous solution of glacial acetic acid; steam heating and stirring the obtained mixed solution to be completely dissolved; adding salicylaldehyde to the solution to catalyze; carrying out heat preservation and racemization; after completing racemization, dropping temperature and filtering to obtain solid DL-lysine salt; adding purified water to the solid DL-lysine salt to dissolve and stirring an obtained solute to decolor; adopting ion exchange to desalt; and concentrating and crystallizing obtained resolution liquid to obtain solid DL-lysine. The method has simple process, strong maneuverability, small pollution in a production process, realization of mass production, lower production cost and good racemization effect, and the purity of an obtained DL-lysine product can be maintained higher than 98 percent.

The invention discloses a low-temperature-resistant rare earth ore flotation collecting agent. The collecting agent comprises, by weight, 30-40 parts of 2-hydroxybenzohydroxamic acid, 30-50 parts of C5-7 hydroxamic acid, 5-15 parts of o-methyl naphthalene hydroxamic acid, 5-10 parts of coconut oil acid and 1-2.5 parts of surface active agents. The invention further provides a preparation method of the collecting agent. The collecting agent is good in water solubility, resistant to low temperature, excellent in selectivity and collecting property, good in flotation performance and easy to degrade, and the defects that an existing collecting agent for industrial application is poor in selectivity and difficult to degrade and needs heating flotation are overcome; and the production technique of the prepared collecting agent is simple and easy to implement, capital construction investment and energy consumption are reduced for enterprises, and the profit of the enterprises is increased.

The invention discloses a preparation method of noctilucent fibers capable of emitting red light in darkness. The preparation method comprises the following steps: mixing 2-hydroxybenzaldehyde with 3-hydroxyl-N,N-dimethylaniline which can be dissolved in water to obtain a mixture, heating the mixture, mixing the mixture with anhydrous zinc chloride and sulfuric acid to obtain a mixture I, and carrying out the reaction on the mixture I to obtain a light conversion agent; mixing the light conversion agent with SrAl2O4:Eu<2+>, Dy<3+> and a fiber forming polymer base material to obtain a mixture II, smelting the mixture II, and granulating to obtain noctilucent particles for spinning; and drying the noctilucent particles, then smelting the noctilucent particles and spinning to obtain the noctilucent fibers. The red light emitted by the noctilucent fibers prepared by adopting the preparation method can be maintained for more than ten hours, the highest luminance can reach 3.0cd/m<2>, the emitted red light is one of three basic colors, and the noctilucent fibers can be compounded with one or two of blue light noctilucent fibers and green light noctilucent fibers to prepare luminous colorful noctilucent fibers, so that the important significance can be realized.

The invention discloses a boron-nitride-type borate lubricating oil additive and a preparation method thereof. The preparation method comprises the following steps: putting tall oil and diethanolamine in a container, and reacting at 100-120 DEG C for 4-5 hours to obtain tall oil acetal amide; mixing salicylaldehyde and n-butylamine, adding ethanol, reacting at 50-60 DEG C in a reflux unit for 2-3 hours, adding the prepared tall oil acetal amide, adding boric acid, and uniformly mixing; reacting at 70-80 DEG C for 1-1.5 hours while keeping the pressure stable at 260-270 mmHg; depressurizing to the stable pressure of 60-70 mmHg, gradually heating to 90-100 DEG C, and reacting for 3-4 hours; and cooling, and filtering to obtain the light yellow liquid. The production method is simple, and has the advantages of low cost, high hydrolysis resistance of the product, high yield and environment friendliness.

The invention relates to a schiff base metal catalyst used in a liquid-phase epoxidation reaction and a preparation method of schiff base metal catalyst, and belongs to the technical field of fine organic chemical industries and catalyst preparation. The schiff base metal catalyst takes salicylaldehyde, an aromatic amine compound and a transition metal compound as raw materials, so that the schiff base metal catalyst containing different metal centers is synthesized, wherein an active component is selected from Mn, Mo, V, Co, Ni and Cu; and the catalytic performance of the schiff base metal catalyst in the liquid-phase epoxidation reaction is provided. An experimental result shows that the catalyst can be used in the epoxidation reaction of multiple olefins, the reaction conditions are mild, and problems of equipment corrosion, polluted wastewater discharge, and the like don't exist. The catalyst has the advantages of high activity and selectivity, simpliness and convenience in recycling and reusability, and is a novel and environment-friendly solid schiff base metal catalyst.

Application of a redox polymer of the poly-[Me(R-Salen)] type onto a conducting substrate is accomplished by the method of electrochemical polymerization. Said polymerization is accomplished by supplying a voltage between the substrate (that serves as an anode) and a counter electrode (that serves as a cathode), with both of them being submerged into the electrolyte containing an organic solvent and the compounds capable of dissolving in said solvent. The process is accompanied by the production of electrochemically inactive (at concentrations of no less than 0.01 mol/l) ions within the range of potentials from −3.0 V to +1.5 V, and metal complex [Me(R-Salen)] dissolved at a concentration of no less than 5·10⁻⁵ mol/l, (where: Me is a transition metal having at least two different degrees of oxidation, R is an electron-donating substituent, Salen is a residue of bis-(salicylaldehyde)-ethylenediamine in Schiff's base.

The invention discloses a copper ion spectrum probe as well as a preparation method and an application thereof. A synthetic method for the copper ion spectrum probe comprises the step of enabling 5-R-salicylaldehyde to react with fluorescein hydrazide to obtain the probe. The probe has a good complexing action with copper ions, so that the spectral absorption is strengthened. In the presence of copper ions, quick change of the color of a solution from colorlessness to yellow can be observed with naked eyes, and a new absorption peak appears at 495nm of the ultraviolet visible absorption spectrum. The stoichiometric ratio of the probe to the copper ions is 1: 1, and the measurement of the copper ions is not disturbed by other common metal ions. The copper ion spectrum probe is easy to synthesize, simple in operation, low in environmental pollution, easy to produce and the like, and has very high selectivity and sensitivity on the copper ions. Therefore, the probe can be used for simply, sensitively and quickly detecting the copper ions, and has practical value in a biosystem and environmental monitoring.