33results about How to "Short cycle of medication" patented technology

The invention discloses a preparation method for a medicament with functions of reinforcing qi and nourishing blood, and nourishing liver and kidney. The medicament is composed of, by weight, 30-80 parts of radix astragali, 80-150 parts of Chinese angelica, 20-60 parts of radix codonopsis, 40-80 parts of donkey-hide gelatin, 30-60 parts of antler gelatin, 20-50 parts of lycium chinensis, 30-60 parts of prepared rehmannia roots, 50-80 parts of white peony roots, 20-30 parts of paper mulberry fruit, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The medicament is advantaged by definite, significant and rapid therapeutic effects and short treatment course. The medicament overcomes the defects of long treated period of medicaments with functions of reinforcing qi and nourishing blood, and nourishing liver and kidney in the prior art. The medicament has no side effects and no adverse reactions.

The invention provides cefotaxime sodium composition freeze-dried powder for injection, relates to the technical field of medicaments and medicament manufacture, and comprises the following raw material components in parts by weight: 7.26-9.17 parts of cefotaxime sodium, 5.78-7.67 parts of chitosan nanoparticles and 81.38-87.10 parts of water for injection. The cefotaxime sodium composition freeze-dried powder for injection disclosed by the invention has the advantages that the chitosan nanoparticles plays a special role in improving the specific surface area and reactivity of the cefotaxime sodium, thus improving the antibacterial effect of the powder; the antibacterial spectrum is widened and the drug resistance is obviously reduced; the medication period of a patient is shortened due to the strengthened activity, and the probability of side reaction caused by accumulated cefotaxime sodium is reduced; and the chitosan nanoparticles can replace mannitol to be used as a freeze-drying skeleton agent for freeze-dried powder, thus eliminating activation of mannitol to a human body.

The invention discloses a medicament for reinforcing qi, nourishing blood and nourishing liver and kidney. The medicament comprises the following raw materials in parts by weight: 30-80 parts of astragalus membranaceus, 80-150 parts of angelica sinensis, 20-60 parts of codonopsis pilosula, 40-80 parts of donkey-hide gelatin, 30-60 parts of deer-horn glue, 20-50 parts of the fruit of Chinese wolfberry, 30-60 parts of prepared rehmannia root, 50-80 parts of radix paeoniae alba, 20-30 parts of fructus broussonetiae, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The medicament is definite in therapeutic effect, remarkable in curative effect, rapid in effect, short in course of treatment and completely free of side effect and untoward effect; and the defects that the conventional medicament is long in period in reinforcing qi, nourishing blood and nourishing liver and kidney are overcome.

The invention relates to a composition for treating acne as well as a preparation method and application thereof. The composition is prepared from the following raw materials in parts by weight: 400 to 1,200 parts of Vaseline, 8 to 80 parts of benzoic acid, 4 to 40 parts of boric acid, 6 to 60 parts of salicylic acid, 40 to 120 parts of ichthammol, 1 to 10 parts of vitamin E, 2 to 15 parts of borneol, 10 to 40 parts of radix sophorae flavescentis, 5 to 25 parts of radix scutellariae, 5 to 25 parts of cortex phellodendri chinensis, 5 to 25 parts of rhizoma coptidis, 10 to 40 parts of radix et rhizoma rhei and 20 to 120 parts of plant essential oil. The composition has the advantages of being short in medication cycle, obvious in curative effects and convenient to use and not influencing daily makeup in a use process. The composition for treating the acne, which is provided by the invention, can be used for quickly permeating a skin, is used for promoting the skin to absorb a medicine, changing a microenvironment, clearing away heat and toxic materials, removing the symptoms of redness, swelling and pain, balancing grease secretion, enabling skin to be fresh, cool, bright and clean, and quickening the skin to heal, is insecticidal and anti-inflammatory, and is applicable to the treatment of the acne which is to various extents and the prevention of the formation of the acne and the mark of the acne.

The invention discloses a Qi reinforcing and blood nourishing and liver and kidney tonifying drug and a preparation method thereof. The Qi reinforcing and blood nourishing and liver and kidney tonifying drug comprises raw materials as follows: by weight, 30-80 parts of radix astragali, 80-150 parts of Chinese angelica, 20-60 parts of radix codonopsis, 40-80 parts of donkey-hide gelatin, 30-60 parts of deerhorn glue, 20-50 parts of wolfberry fruit, 30-60 parts of prepared rehmannia root, 50-80 parts of white peony root, 20-30 parts of paper mulberry fruit, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The Qi reinforcing and blood nourishing and liver and kidney tonifying drug has definite therapeutic effect, obvious curative effect, quick effect, short course of treatment, overcomes defects that drug use cycles of the prior art Qi reinforcing and blood nourishing and liver and kidney tonifying drugs are long, and completely has no side effect and no adverse reaction.

The invention provides a fosfomycin sodium composition lyophilized powder for injection, and relates to the technical field of medicines and medicine preparation. The fosfomycin sodium composition lyophilized powder for injection comprises the following raw materials in parts by weight: 7.26-9.17 parts of fosfomycin sodium, 7.02-8.97 parts of chitosan nanoparticle, and 81.38-87.10 parts of injection water. The fosfomycin sodium composition lyophilized powder for injection has the following advantages that (1) the antibacterial effect on klebsiella pneumoniae is good, the antibiotic sensitive rate is 89.9%, and the advantage in klebsiella pneumoniae producing ESBLs (Extended Spectyum beta Lactamase) is obvious; (2) the stability on beta-lactamase produced by gram-negative bacterium is increased, and the in-vivo distribution is good; (3) as the activity is improved, the medication period of a patient is shortened, and the possibility of untoward effect caused by the accumulation of fosfomycin sodium is reduced; and (4) the chitosan nanoparticle can replace mannitol to function as the lyophilization skeleton agent of the lyophilized powder, and the activation effect on a human body by the mannitol is eliminated.

The invention provides a cefpiramide sodium composition freeze-dried injection for injection, and relates to the technical field of medicines and medicine preparation. The cefpiramide sodium composition freeze-dried injection for injection comprises the following raw material components in parts by weight: 7.26-9.17 parts of cefpiramide sodium, 5.78-7.67 parts of chitosan nanoparticles and 81.38-87.10 parts of water for injection. The cefpiramide sodium composition freeze-dried injection for injection has the advantages that 1) the in vitro antimicrobial activity spectrum is wider and covers Gram-positive bacteria and Gram-negative bacteria (comprising Pseudomonas aeruginosa), the characteristics that the G+ bacterial and Pseudomonas aeruginosa resistance of the third and fourth generation cephalosporin and the activity of anaerobic bacteria are poor, and research and development direction of cephalosporin is met; 2) the injection is good in stability, thus greatly reducing the risk that the product quality is greatly reduced in production and circulation links (particularly commercial circulation; 3) the activity is enhanced, so that the medication period of the patient is shortened, and the probability of adverse reaction caused by accumulation of cefpiramide sodium is reduced; 4) the chitosan nanoparticles can replace mannitol as a freeze-dried skeleton agent of the freeze-dried injection, so that the activity of mannitol on human body is eliminated.

The invention provides a ceftriaxone sodium composition freeze-dried powder for injection, and belongs to the field of medicine and medicine preparation technology. The ceftriaxone sodium composition freeze-dried powder comprises following raw material ingredients, by weight, 7.26 to 9.17 parts of ceftriaxone sodium, 5.78 to 7.67 parts of chitosan nanoparticle, and 81.38 to 87.10 parts of injection water. Advantages of the ceftriaxone sodium composition freeze-dried powder are that: 1) activity of the ceftriaxone sodium composition in treatment of gonorrhoea is increased significantly, so that combination medication of other antibiotics with ceftriaxone sodium with unknown action mechanisms is avoided in clinic; 2) antibacterial spectrum is widened, and drug tolerance is reduced greatly; 3) improvement of activity is capable of shortening medication cycle of patients, and reducing occurrence likelihood of adverse reaction caused by accumulation of ceftriaxone sodium; and 4) the chitosan nanoparticle can be used as a freeze-dried skeleton agent of the freeze-dried powder injection instead of mannitol, so that active effects of mannitol on human bodies are avoided.

The invention discloses a medicament for reinforcing qi, nourishing blood and nourishing liver and kidney. The medicament comprises the following raw materials in parts by weight: 30-80 parts of astragalus membranaceus, 80-150 parts of angelica sinensis, 20-60 parts of codonopsis pilosula, 40-80 parts of donkey-hide gelatin, 30-60 parts of deer-horn glue, 20-50 parts of the fruit of Chinese wolfberry, 30-60 parts of prepared rehmannia root, 50-80 parts of radix paeoniae alba, 20-30 parts of fructus broussonetiae, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The medicament is definite in therapeutic effect, remarkable in curative effect, rapid in effect, short in course of treatment and completely free of side effect and untoward effect; and the defects that the conventional medicament is long in period in reinforcing qi, nourishing blood and nourishing liver and kidney are overcome.

The invention discloses a traditional Chinese medicine preparation treating chronic pharyngitis and a preparation technology thereof. The preparation is characterized by being prepared from polygala japonica, momordica grosvenori, honeysuckle, oroxylum indicum, rabdosia rubescens, scrophulariae, Indian strawberries, oldenlandia diffusa, radix pseudostellariae, terminalia chebula retz, lygodium japonicum, peach kernels, herba houttuyniae, liquorice and Chinese yam. The traditional Chinese medicine preparation can effectively reduce medicine cost, eliminates toxic and side effects, shortens drug use period, guarantees definite curative effects and treats both symptoms and root causes. The adopted technology is simple in process, convenient to operate, and capable of achieving industrial production and facilitating application and popularization of the traditional Chinese medicine preparation.

The invention discloses an administration tank for medical oncology treatment by combining the traditional Chinese medicine with the western medicine and relates to the technical field of medical equipment. The administration tank comprises a medicine bottle, wherein an annular groove formed in a bottle opening of the medicine bottle is overlapped with a hollow ring; a filter screen cylinder is fixedly connected with the inside of the hollow ring; an extrusion plate is slidably connected with the inside of the filter screen cylinder; and a connecting rod is fixedly connected to the top of theextrusion plate. According to the administration tank for medical oncology treatment by combining the traditional Chinese medicine with the western medicine, a sliding rod, a sliding plate and a piston pad are driven to move upwards by pulling a pulling plate upwards; in the upward moving process of the piston pad, a liquid medicine in a liquid medicine chamber is pumped into a piston chamber through a liquid pumping pipe by utilizing negative pressure; and when medical staff do not pull the pulling plate any more, the sliding plate and the piston pad move downwards by means of the elastic force of a spring, and in the downward moving process of the piston pad, the liquid medicine in the piston chamber flows to the incision of a patient through a liquid outlet pipe and a liquid outlet headto perform medication treatment on the incision, so that the medication period of the patient is shortened, and the rehabilitation of the patient is facilitated.

The invention provides a pharmaceutical composition for treating burns and scalds as well as a preparation method and application thereof. The pharmaceutical composition is prepared from an effectivecomponent a and an effective component b, <0}{0><}0{>wherein the component a has the effects of clearing away heat and toxic materials as well as diminishing inflammation and relieving pain and is prepared from the following raw materials: 10-40 parts of giant knotweed rhizome, 5-35 parts of dandelion herb, 5-35 parts of lithospermum herb and 1-20 parts of borneol; <0}{0><}0{>and the component b has the effects of promoting blood circulation and removing blood stasis as well as removing necrotic tissue and promoting tissue regeneration and is prepared from the following raw materials: 10-40 parts of radix et rhizoma rhei, 10-40 parts of garden burnet root, 1-20 parts of radix codonopsis, 1-20 parts of radix astragali and 50-200 parts of egg white. <0}{0><}0{>The pharmaceutical compositionhas the advantages that medicines are respectively applied according to different effects of the traditional Chinese medicines, so that synergetic effects of the Chinese traditional medicine components can be fully exerted; compared with single drug prescription administration, the pharmaceutical composition has more obvious and stable curative effects; <0}{0><}0{>the pharmaceutical composition ismainly used for treating diseases caused by red, swollen, hot and painful wounds in preliminary and intermediate stages of burns and scalds and obvious exudation, reducing wound infection, accelerating wound healing and effectively reducing formation of ulcers at burn and scald parts, and is low in cost and free of toxic or side effect; <0}{0><}0{>and the preparation method of the pharmaceuticalcomposition is simple and feasible, all parameters are controllable, and large-scale production is facilitated.

The invention provides a cefonicid sodium composition powder for injection, and belongs to the field of medicine and medicine preparation technology. The cefonicid sodium composition powder comprises following raw material ingredients, by weight, 7.26 to 9.17 parts of cefonicid sodium, 5.16 to 6.50 parts of chitosan nanoparticle, and 82.38 to 88.10 parts of injection water. dvantages of the cefonicid sodium composition powder are that: 1) antibacterial effect of the cefonicid sodium composition on Gram-negative escherichia coli and Gram-positive micrococcus tetragenus is increased significantly; 2) the chitosan nanoparticle is capable of passing through tissue spaces, staying in tissues and cells for a long period of time, and releasing medicines; and after intravenous injection, the chitosan nanoparticle is mainly gathered in organs with abundant mononuclear macrophages, especially in liver and bone marrow; 3) improvement of activity is capable of shortening medication cycle of patients, and reducing occurrence likelihood of adverse reaction caused by accumulation of cefonicid sodium; and 4) the chitosan nanoparticle can be used as a freeze-dried skeleton agent of the freeze-dried powder injection instead of mannitol, so that active effects of mannitol on human bodies are avoided.

The invention relates to a spray with geniposide and polyene phosphatidyl choline as active ingredients as well as a preparation technology and application of the spray. The spray is a pharmaceuticalcomposition which is prepared by selecting the geniposide and the polyene phosphatidyl choline as active pharmaceutical ingredients and mixing the active pharmaceutical ingredients with pharmaceutically acceptable auxiliary materials. The spray disclosed by the invention enables the geniposide and the polyene phosphatidyl choline to be directly distributed in nasal cavity, trachea, bronchia and lungs and can be used for treating respiratory system diseases such as asthma and bronchitis. The composition can synergistically and effectively play drug effects which are significantly better than those of single-dose geniposide or polyene phosphatidyl choline; the composition has the characteristics of enhancing treatment effects, shortening medication cycle and the like. The spray prepared anddeveloped by technical means disclosed by the invention has the advantages of fast onset, rapid effects, convenience in use and the like.

The invention discloses a bacteriostatic agent as well as a preparation method and application thereof. The bacteriostatic agent is prepared from the following raw materials in parts by mass: 230 to 270 parts of radix sophorae flavescentis, 230 to 270 parts of Cortex Pseudolaricis, 230 to 270 parts of radix arnebiae seu lithospermi, 80 to 120 parts of radix stemonae, 180 to 220 parts of radix astragali mushrooms, 80 to 120 parts of fructus cnidii and 28 to 32 parts of borneol. Bacteriostatic gel prepared by the following steps of weighing, water extraction, alcohol precipitation, preparation,dissolution, stirring, mixing, filling and the like has the remarkable advantages of relatively strong bacteriostatic ability, capability of effectively solving the tinea pedis problem of skin itch caused by staphylococcus aureus, candida albicans, escherichia coli and the like, good transdermal effect, no side effect, high safety, fast action and high stability, does not pollute the environment,has no irritation on the human body and animals, and has no toxic and side effects.

The application discloses a bacteriostatic agent, a preparation method and an application thereof. The antibacterial agent is made of the following raw materials in parts by mass: 180-220 parts of Smilax cocos, 180-220 parts of Curcuma, 130-170 parts of Sophora flavescens, 130-170 parts of Cortex Phellodendri, 130-170 parts of Fructus Cnidii, 80-parts of safflower 120 servings and borneol 28‑32 servings. The antibacterial gel made by the following steps: weighing, alcohol extraction, water extraction, alcohol precipitation, preparation, dissolution, stirring, mixing, filling, etc. has strong antibacterial ability and can effectively solve Staphylococcus aureus, white Gynecological itching caused by Candida, Escherichia coli, etc., good transdermal effect, no side effects, high safety, fast action speed, good stability, no pollution to the environment, no stimulation to humans and animals, no toxic side effects .

The invention discloses an extract for inhibiting liver cancer cells and in a saussurea involucrata culture and a preparation thereof for treating liver cancer. The extract is obtained by taking the saussurea involucrata culture as a raw material and chloroform or n-butanol as an organic solvent for backflow extraction. It is accidentally found for the first time that the extract extracted by taking chloroform or n-butanol as the organic solvent has excellent inhibiting effect on HepG2 cells and Hep3B cells of liver cancer and is short in medication cycle, and the problem that existing preparations for treating the liver cancer are long in medication cycle can be solved effectively. The preparation contains chloroform extract or n-butanol extract, thereby having the advantages of excellent liver cancer cell inhibiting effect and short medication cycle.

The invention discloses a Qi reinforcing and blood nourishing and liver and kidney tonifying drug and a preparation method thereof. The Qi reinforcing and blood nourishing and liver and kidney tonifying drug comprises raw materials as follows: by weight, 30-80 parts of radix astragali, 80-150 parts of Chinese angelica, 20-60 parts of radix codonopsis, 40-80 parts of donkey-hide gelatin, 30-60 parts of deerhorn glue, 20-50 parts of wolfberry fruit, 30-60 parts of prepared rehmannia root, 50-80 parts of white peony root, 20-30 parts of paper mulberry fruit, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The Qi reinforcing and blood nourishing and liver and kidney tonifying drug has definite therapeutic effect, obvious curative effect, quick effect, short course of treatment, overcomes defects that drug use cycles of the prior art Qi reinforcing and blood nourishing and liver and kidney tonifying drugs are long, and completely has no side effect and no adverse reaction.

The invention belongs to the technical field of medicines, and particularly relates to application of Onalspib in preparation of a medicine for preventing and / or treating adenovirus infection. The invention discloses an application of Onalspib in preparation of a medicine for inhibiting adenovirus and / or a medicine for preventing and / or treating adenovirus infection, so that a safe and effective small molecular compound is provided for clinically treating adenovirus. The Onalspib can effectively inhibit the replication of the adenovirus in a non-toxic range, can be further developed into a medicine for treating or preventing diseases caused by adenovirus infection, and has a wide application prospect.

The invention discloses a traditional Chinese medicine composition capable of treating insomnia. The traditional Chinese medicine composition capable of treating insomnia is prepared from the following components in parts by weight: 15-30 parts of gypsum fibrosum, 10-30 parts of dragon bone, 15-30 parts of concha ostreae, 5-10 parts of radix et rhizoma rhei, 5-10 parts of rhizoma coptidis, 5-15 parts of radix rehmanniae, 10-30 parts of semen ziziphi spinosae, 5-15 parts of radix polygalae, and 10-15 parts of radix bupleuri. The formula is reasonable, the monarch drug, the minister drug, the assistant drug and the guide drug coordinate with each other, so that the traditional Chinese medicine composition capable of treating insomnia can tranquilize the mind by nourishing the heart, clear heart fire to relieve fidgetiness, tonify the kidney and brain, tranquilize and allay excitement, quiet spirit and stabilize mind. The traditional Chinese medicine composition capable of treating insomnia is low-cost, has no toxic and side effects to a human body, develops no dependence when being used for long, takes into effect rapidly and has a short treatment cycle. The traditional Chinese medicine composition is suitable for insomnia.

The invention relates to applications of tripterine in preparation of drugs for treating complex refractory depression. The complex refractory depression is a refractory chronic mental disorder, and up to now, the lack of safe and effective clinical intervention still troubles people. The tripterine has the characteristics of being low in toxicity and high in safety. The invention firstly discloses that the tripterine has the precise and significant efficacy of treating complex depression complicated by major chronic diseases such as neuropathic pain and metabolic syndromes.

The invention discloses a hair growth formula containing dodecyl dimethyl amine oxide, 10-30 grams of dodecyl dimethyl amine oxide, 10-40 grams of saponin, 5-25 grams of cypress seeds, black sesame seeds 9-15 grams, 9-30 grams of black beans, 2-10 grams of saffron, 20-40 grams of saffron, 10-30 grams of raw land, 25-35 grams of honey and 1000 grams of white wine; the dodecyl dimethyl oxide Amine, saponin, cypress kernel, black sesame, black bean, saffron, rehmannia, raw land and honey are soaked in liquor for one month. The beneficial effects of the invention are: no ineffective ingredients, low cost, short and convenient medication cycle, and good hair growth formula for hair loss caused by various etiologies.

The application relates to the application of tripterine in the preparation of medicines for treating complex refractory depression. Complex refractory depression is a refractory chronic mental disorder, so far there is no safe and effective clinical intervention. Tripterygium has the characteristics of low toxicity and high safety. This application discloses for the first time that tripterygne has definite and significant curative effect on treating complex depression complicated by major chronic diseases such as neuropathic pain and metabolic syndrome.

The invention belongs to the technical field of medicines, and particularly relates to application of BIIB021 in preparation of a medicine for preventing and / or treating adenovirus infection. The invention discloses an application of BIIB021 in preparation of a medicine for inhibiting adenovirus and / or a medicine for preventing and / or treating adenovirus infection, thereby providing a safe and effective small molecule compound for clinically treating adenovirus. The BIIB021 can effectively inhibit the replication of the adenovirus in a non-toxic range, can be further developed into a medicine for treating or preventing diseases caused by adenovirus infection, and has a wide application prospect.

The invention relates to a herbal medicine formula for treating whole body fester and application thereof. The herbal medicine formula comprises 3-8 g of polygonum cuspidatum, 5-12 g of saxifraga stolonifera, 3-7 g of borneol, 3-13 g of sanguisorba officinalis, 8-20 g of astragalus membranaceus, 10-15 g of scutellaria baicalensis, 15-27 g of angelica sinensis, 17-21 g of gypsum, 12-18 g of chrysanthemum, 20-27 g of golden cypress, 2-6 g of liquorice, 23-29 g of angelica dahurica and 13-24 g of radix scrophulariae. The formula medicine is simple to use, non-toxic, harmless to a human body, short in medication period, low in cost and remarkable in effect, and the medicine can shorten the hospitalization time of a patient, reduce the economic expenditure and avoid the harm to the human body caused by surgical amputation.

The invention relates to a preparation method of ultrasound-targeted microbubbles carrying simvastatin, which comprises dissolving simvastatin in tetrahydrofuran and diluting physiological saline to a concentration of 0.01-0.1 mg / mL; adding trimethyl chitosan, Sodium tripolyphosphate, then, compounded into a stable space network, obtained a suspension, freeze-dried and redissolved, transferred the obtained liquid to a vial filled with C3F8 gas, and vibrated the vial with a mechanical oscillator to form a 0.05 mg / mL simvastatin microbubbles, fill the remaining space of the vial with high-pressure C3F8 gas and seal it up, and refrigerate it for later use; inject simvastatin microbubbles into the knee joint cavity and apply ultrasound at the same time, control the ultrasound intensity and time, and target to induce microbubble rupture to reach the maximum ratio. The administration is highly targeted, the medication cycle is shortened, the side effects of long-term medication are reduced, and the dosage of the medication is reduced.

The invention discloses a preparation method for a medicament with functions of reinforcing qi and nourishing blood, and nourishing liver and kidney. The medicament is composed of, by weight, 30-80 parts of radix astragali, 80-150 parts of Chinese angelica, 20-60 parts of radix codonopsis, 40-80 parts of donkey-hide gelatin, 30-60 parts of antler gelatin, 20-50 parts of lycium chinensis, 30-60 parts of prepared rehmannia roots, 50-80 parts of white peony roots, 20-30 parts of paper mulberry fruit, 30-50 parts of pyrola, 25-35 parts of longan aril, 10-20 parts of cane sugar, 20-30 parts of soluble starch and 15-25 parts of dextrin. The medicament is advantaged by definite, significant and rapid therapeutic effects and short treatment course. The medicament overcomes the defects of long treated period of medicaments with functions of reinforcing qi and nourishing blood, and nourishing liver and kidney in the prior art. The medicament has no side effects and no adverse reactions.

The invention provides levofloxacin composition freeze-dried powder for injection, relates to the technical field of medicaments and medicament preparation, and comprises the following raw material components in parts by weight: 7.26-9.17 parts of levofloxacin, 4.65-6.76 parts of chitosan nanoparticles and 73.34-87.10 parts of water for injection. The levofloxacin composition freeze-dried powder for injection disclosed by the invention has the advantages that the composition can maintain a higher drug concentration for a long term, and thus the levofloxacin composition freeze-dried powder has a certain slow release function; compared with the single used levofloxacin, the composition has an obvious colon specific targeted drug release characteristic during in-vivo drug release; the antibacterial activity is obviously enhanced and the medication period of a patient is shortened, and the probability of side reaction caused by accumulated levofloxacin is reduced; and the chitosan nanoparticles can replace mannitol to be used as a freeze-drying skeleton agent for freeze-dried powder, thus eliminating activation of mannitol to a human body.

The invention relates an enteric-coated sustained release preparation which takes rhizoma paridis yunnanensis total saponins and polyene phosphatidyl choline as active ingredients, and is mainly usedfor preventing and treating liver injury diseases. The sustained release oral solid preparation is prepared from the rhizoma paridis yunnanensis total saponins, the polyene phosphatidyl choline and pharmaceutically acceptable auxiliary materials, wherein the rhizoma paridis yunnanensis total saponins and the polyene phosphatidyl choline are medicinal active ingredients. The composition is dissolved in intestinal tracts and delays a medicine releasing speed, the influence of a gastric acid on the active ingredients of the rhizoma paridis yunnanensis total saponins and the polyene phosphatidyl choline is avoided, a situation that gastric mucosa is irritated due to long-term medicine taking is avoided, and adverse reactions, including nausea, emesis, bellyache, diarrhea and the like, caused by taking medicines can be reduced. The composition can synergistically and effectively perform the curative effect of the medicine, is obviously superior to an effect obtained when the same dosage ofrhizoma paridis yunnanensis total saponins or polyene phosphatidyl choline is singly used, and has the characteristics that a treatment effect is enhanced, the taking frequency of the medicine is reduced, medicine utilization compliance is improved, the cytotoxicity of the rhizoma paridis yunnanensis total saponins is lowered and the like.