30results about How to "Reduce the possibility of degradation" patented technology

Disclosed are water soluble polymeric reagents comprising the structure POLY-[Y—S—W]x, where POLY is a water soluble polymer; Y is a hydrocarbon-based spacer group, x is 1 to 25, and S—W is a thiol, protected thiol, or thiol-reactive derivative. Preferably, the water soluble polymer is a PEG polymer. Also disclosed are conjugates of such polymeric reagents with pharmaceutically relevant molecules, and methods of their formation and use.

Disclosed are water soluble polymeric reagents comprising the structure POLY-[Y—S—W]x, where POLY is a water soluble polymer; Y is a hydrocarbon-based spacer group, x is 1 to 25, and S—W is a thiol, protected thiol, or thiol-reactive derivative. Preferably, the water soluble polymer is a PEG polymer. Also disclosed are conjugates of such polymeric reagents with pharmaceutically relevant molecules, and methods of their formation and use.

Systems and methods for operating an engine that includes a cavity in an exhaust manifold of a turbocharged engine are described. The systems and methods may improve engine efficiency and provide a way of controlling temperatures of engine exhaust components. The cavity may be located between an exterior wall of the exhaust manifold and an interior wall of the exhaust manifold.

The application relates to the field of TPE particles, and specifically discloses an aging-resistant TPE particle and a preparation method thereof. An aging-resistant TPE particle is made of raw materials comprising the following parts by weight: a base material mixed with SBS and SEBS; rubber oil; oil-locking additive; filler; toner; antioxidant; anti-aging additive; its preparation The method is as follows: mix the base material with rubber oil, stir evenly and let it stand for 30-60 minutes to obtain a first-class mixture; put oil-locking additives, fillers, toner, antioxidants and anti-aging additives into the first-class mixture, mix homogeneously to obtain a secondary mixture; extrude, pelletize, and dry to obtain TPE pellets. The anti-aging TPE granules of the present application have better aging resistance and longer service life; in addition, the preparation method of the present application is simple to operate, can promote the full reaction of each raw material component, and ensures that the TPE granules have better anti-aging performance.

The present invention provides a heating device capable of dispensing heated personal care product while containers thereof are being heated. For example, there could be a base having multiple wells with a heating system associated with each well. There could be separate control of the heat in each well. The wells have an upper opening for permitting insertion of a container in them (in inverted fashion), and a side opening for permitting heated material in a container to be dispensed from the container while a portion of the container is being heated in the well. In another form, the invention provides a temperature sensor at the bottom of a heating well that projects into a heat conductive head of a container being warmed in the well. Methods for using such devices are also disclosed.

An integrated device for sample extraction, purification and concentration, including a solvent system, a sample extraction system, a sample purification system, a sample concentration system and a computer; wherein: the solvent system provides necessary solvents for the sample extraction and purification steps; the sample extraction system adopts advanced After pre-freezing the sample with liquid nitrogen, the method of organic solvent extraction is carried out. The extract is stored in the buffer pool and injected into the sample purification system by high-purity nitrogen. The sample purification system includes acid silica gel column, composite silica gel column, alumina column, Commercial packed columns such as activated carbon columns can be used for single-column and multi-column series purification; the sample concentration system uses the heat generated by resonance of nano-gold or nano-silver particles to evaporate and concentrate the sample solution, and the concentrated solution is transferred to the sample receiving bottle. Sample pretreatment process.

The invention discloses senile dementia Ad-GFP gene vaccine and a preparation method thereof and is Ad-GFP vaccine of flexible foldable multivalence Beta- amyloid 1-15 (ABeta1-15) of secretion co-expression and genetic adjuvant, which a flexible connecting peptide is used for connecting multivalence. The invention selects foldable multivalence ABeta1-15 as immunogen, which avoids the space rigid structure of multiple copy ABetaB cell epitopes, also ensures that ABeta15 epitopes are more easily exposed, thus enhancing immunogenicity and also increasing immunogenic molecular weight and reducing the possibility of degradation; a antigen delivery system that takes adenovirus as a carrier is selected, which avoids the defects of high challenge and high cost of chemosynthesis.

The invention mainly provides a method for highly expressing antimicrobial peptides in yeast. The method provided by the present invention comprises the fusion expression of an antimicrobial peptide and a red fluorescent protein, and in the recombinant yeast, the level of antimicrobial peptide production in the strain can be judged by the color depth visible to the naked eye, so as to quickly screen out highly expressed antimicrobial peptides and Engineering strains with strong antibacterial activity. The invention also provides a recombinant fusion protein with antibacterial activity and engineering recombinant bacteria, which can be directly applied in industry or feed industry.