561 results about "Multiple copy" patented technology

Multiple applications request data from multiple storage units over a computer network. The data is divided into segments and each segment is distributed randomly on one of several storage units, independent of the storage units on which other segments of the media data are stored. At least one additional copy of each segment also is distributed randomly over the storage units, such that each segment is stored on at least two storage units. This random distribution of multiple copies of segments of data improves both scalability and reliability. When an application requests a selected segment of data, the request is processed by the storage unit with the shortest queue of requests. Random fluctuations in the load applied by multiple applications on multiple storage units are balanced nearly equally over all of the storage units. This combination of techniques results in a system which can transfer multiple, independent high-bandwidth streams of data in a scalable manner in both directions between multiple applications and multiple storage units.

The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.

Methods and apparatus for genome analysis are provided. A microfabricated structure including a microfluidic distribution channel is configured to distribute microreactor elements having copies of a sequencing template into a plurality of microfabricated thermal cycling chambers. A microreactor element may include a microcarrier element carrying the multiple copies of the sequencing template. The microcarrier element may comprise a microsphere. An autovalve at an exit port of a thermal cycling chamber, an optical scanner, or a timing arrangement may be used to ensure that only one microsphere will flow into one thermal cycling chamber wherein thermal cycling extension fragments are produced. The extension products are captured, purified, and concentrated in an integrated oligonucleotide gel capture chamber. A microfabricated component separation apparatus is used to analyze the purified extension fragments. The microfabricated structure may be used in a process for performing sequencing and other genetic analysis of DNA or RNA.

A facility stores attachments for electronic mail messages so that the messages may be transmitted to the intended recipients without the attachments. The recipients may then review and / or download the attachments by contacting the facility. This facility is especially useful in instances wherein the attachments are large. The facility eliminates the need to store multiple copies of the attachment throughout a system; thus consuming a great deal of memory space. In addition, the facility prevents the recipient from extensive delays that are often associated with downloading email messages that contain large attachments via a dial-up connection with a low transmission rate. The facility may be realized as a server and may be a web server so as to provide access to the attachments via an IP network.

A monitoring system for a distributed environment including a plurality of hosts capable of executing multiple copies of a scalable application includes a first device for generating first data corresponding to performance of all copies of the scalable application; a second device for generating second data corresponding to performance of all host in the distributed environment; and a third device for generating performance metrics based on the first and second data.

The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, comprising the steps of: a) compartmentalising the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsule; and b) identifying the compound which binds to or modulates the activity of the target; wherein at least one step is performed under microfluidic control. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.

The invention relates to Agrobacterium mediated transformation of moulds comprising species of the fungal sub-divisions Ascomycotina, Basidiomycotina, Deuteromycotina, Mastigomycotina, and Zygomycotina.Examples demonstrate the transformation of Aspergillus awamori (both protoplasts and conidia), Aspergillus nidulans, Aspergillus niger, Colletotrichum gloeosporioides, Fusarium solani pisi, Neurospora crassa, Trichoderma reesei, Pleurotus ostreatus and Agaricus bisporus (all conidia), and Fusarium graminearum (both conidia and rehydrated freeze dried ATCC material).Especially for Aspergillus awamori the transformation frequency is much higher than with conventional mould transformation techniques.It has further been found that not only one expressable gene can be introduced into these moulds, but even multiple copies of such gene, which, moreover, can be targeted e.g. in the chromosomal pyrG locus, as exemplified for A. awamori. These multiple copies can be of a gene encoding a desired, homologous or heterologous, protein.

The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsules; and identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.

A satellite communication system includes a plurality of satellites, such as low earth orbit satellites, and a plurality of gateways. The satellite communication system is bidirectionally coupled to a terrestrial communication system through at least the plurality of gateways. The satellite communication system and the terrestrial communications system together form a data communication network having a plurality of nodes including source nodes, destination nodes and intermediate nodes. Multiple copies of a packet can coexist within the data communication network, and the packet and its one or more copies are routed, using at least in part satellite-resident routers and gateway-resident routers, over a plurality of different paths between a particular source node and a particular destination node. At least one duplicate copy of a given packet is simply not used during the execution of a packet reordering procedure in the destination node, or at an intermediate node. Certain of the paths are carried over satellite-to-satellite cross-links, while certain other ones of the paths are carried over satellite-to-gateway uplinks and downlinks, and at least one path exists between a user terminal and at least one satellite. In a preferred embodiment the packets are TCP / IP (or equivalent protocol) packets containing information for enabling the selective destruction of a duplicate packet to occur.

A method for controlling errors in a wireless link layer using a simultaneous multiple copy scheme and an adaptive forward error correction (FEC) scheme in a wideband wireless communication is provided. The method for controlling errors in a link layer in wideband wireless communication using an automatic repeat request (ARQ) scheme, in which a wideband wireless channel is used for communication between a first node and a second node, includes the steps of (a) estimating the error ratio of a forward (a direction in which a cell is transmitted from the first node to the second node) channel using the state of a backward (a direction in which a cell is transmitted from the second node to the first node) channel, and transmitting a cell, in which a forward error correction (FEC) code having an encoding ratio that varies depending on the estimated error ratio is included in a protocol data unit (PDU) of a wireless link layer, through the forward channel and (b) re-transmitting the copy of a cell transmitted in the step (a), when feedback information that indicates that an error exists in the cell transmitted in the step (a) is received through the backward channel. It is possible to reduce the number of times of re-transmission by improving the probability of correcting forward errors using more error controlling bits as the state of the channel is worse and to minimize the waste of resources using less error controlling bits as the state of the channel is better, to thus obtain the optimal performance and guarantee the minimum delay time.

Methods and apparatus for genome analysis are provided. A microfabricated structure including a microfluidic distribution channel is configured to distribute microreactor elements having copies of a sequencing template into a plurality of microfabricated thermal cycling chambers. A microreactor element may include a microcarrier element carrying the multiple copies of the sequencing template. The microcarrier element may comprise a microsphere. An autovalve at an exit port of a thermal cycling chamber, an optical scanner, or a timing arrangement may be used to ensure that only one microsphere will flow into one thermal cycling chamber wherein thermal cycling extension fragments are produced. The extension products are captured, purified, and concentrated in an integrated oligonucleotide gel capture chamber. A microfabricated component separation apparatus is used to analyze the purified extension fragments. The microfabricated structure may be used in a process for performing sequencing and other genetic analysis of DNA or RNA.

Data structures, a method, and an associated transmission system for multicast transmission on network processors in order both to minimize multicast transmission memory requirements and to account for port performance discrepancies. Frame data for multicast transmission on a network processor is read into buffers to which are associated various control structures and a reference frame. The reference frame and the associated control structures permit multicast targets to be serviced without creating multiple copies of the frame. Furthermore this same reference frame and control structures allow buffers allocated for each multicast target to be returned to the free buffer queue without waiting until all multicast transmissions are complete.

The invention describes a method for the identification of compounds which bind to a target component of a biochemical system or modulate the activity of the target, by compartmentalizing the compounds into microcapsules together with the target, such that only a subset of the repertoire is represented in multiple copies in any one microcapsules; and identifying the compound which binds to or modulates the activity of the target. The invention enables the screening of large repertoires of molecules which can serve as leads for drug development.

A storage controller, cooperable with host computer apparatus, and a plurality of controlled storage apparatus, comprises a host write component operable to write a data object to a source data image at one of the plurality of controlled storage apparatus; a first copy component responsive to a first metadata state and operable to control copying of the data object to a first target data image at one of the plurality of controlled storage apparatus; a second copy component responsive to a second metadata state and operable to perform one of: controlling copying of the data object to a second target data image at one of the plurality of controlled storage apparatus; and causing the first copy component to perform copying of the second target data image to the first target data image.

A system for testing middleware of applications in the N-tiered model. The test system contains test code generators, test engines to execute multiple copies of the test code and a data analyzer to analyze and present the results to a human user. The system is able to automatically generate test code to exercise components of the middleware using information about these components that would otherwise be available to the application under test. Multiple copies of the test code are executed in a synchronized fashion. Execution times of multiple events are recorded and then presented in one of several formats. With the system, an application developer can identify components that represent performance bottlenecks or can gather information on deployment properties of individual components that can be used to enhance the performance of the application under test.

A system for remotely testing middleware of applications in the N-tiered model across a network. The test system contains test code generators, test engines to execute multiple copies of the test code and a data analyzer to analyze and present the results to a human user. The system is able to automatically generate test code to exercise remotely located components of the middleware using information about these components that would otherwise be available to the application under test. Multiple copies of the test code are executed in a synchronized fashion. Execution times of multiple events are recorded and then presented in one of several formats. By use of the system, an application developer can receive test results about components that represent performance bottlenecks or can be made aware of information on deployment properties of individual components that can be used to enhance the performance of the application under test.

A monitoring system for a distributed environment including a plurality of hosts capable of executing multiple copies of a scalable application includes a first device for generating first data corresponding to performance of all copies of the scalable application; a second device for generating second data corresponding to performance of all host in the distributed environment; and a third device for generating performance metrics based on the first and second data.

Because correct configuration data is essential to the operation of any RAID system, and because multiple copies of the configuration data are kept, not only in the RAID controller itself, but also in each disk drive unit in the configuration, it is imperative that the various copies of the configuration data do not become "out of synchronization", which means that one or more copies of the configuration data are different from one or more other copies of the configuration data. To maintain synchronization of all copies of the configuration data, the current invention compares the configuration data stored in the RAID controllers' NVRAM to that of the current system, and records any new, non-responding, repositioned or unidentified storage devices in a change list. The identities and the attachment points of any storage devices in the change list are then displayed to the user, and various options for correcting the lack of synchronization are provided by enabling one or more function keys that may be selected by the user. One such function key, an "accept change" key, causes the configuration data to be modified by changing the current operational state of any non-responding storage device. A "configuration adjustment" key, when selected by the user, causes the configuration data to be modified to reflect any changes in the attachments points of any repositioned storage deices. An "import configuration" key causes the configuration data to be changed to correspond to that of an unidentified storage device. And a "retry" key gives the user an opportunity to rearrange the system and then re-compares the configuration data in the controller to the current system configuration. When the system is operating in un-attended mode, means are disclosed to automatically perform the "accept change", "configuration adjustment" and "import configuration" functions in priority order so long as the "retry" key has not been enabled. The retry key implies attended operation.

Paralleling processing system and method. When clusters are formed based on strongly connected components, a single cluster (fat cluster) having at least a predetermined number of blocks, or an expected processing time exceeding a predetermined threshold, is formed. The fat cluster is subjected to an unrolling process to make multiple copies of the processing of the fat cluster and to assign the copies to individual processors. Processing of the fat cluster is executed by the multiple processor devices in a pipelined manner. If a fat cluster to be iteratively executed cannot be executed in the pipelined manner because a processing result of an nth iteration of the fat cluster depends on a processing result of a preceding iteration of the fat cluster an input value needed for execution of the fat cluster is generated based on a certain prediction, and the fat cluster is speculatively executed.

The methods of the present invention provide methods for manufacturing a master substrate and methods for manufacturing replica arrays from the master substrate. The methods may be used, for example, directly to manufacture or “print” peptide arrays from a DNA array; however, the methods are applicable to a wide range of manufacturing applications for use any time multiple copies of an array needs to be printed.

Closed loop wireless communication of signals using an adaptive transmit antenna array, in which multiple copies of signals to be transmitted by the transmit antenna array are produced with delays and weights that are functions of the multi-path transmission channel characteristics from the transmit antenna array to a receive antenna array of a receiver and are combined before transmission by the transmit antenna array. The delays and weights of the transmit copies for each transmit antenna element are functions of the respective multi-path transmission channel characteristics from that transmit antenna element to the receive antenna array such that the multi-path signal components propagated to each receiver element are received with distinguishable delays according to the propagation path. The receiver combines the received signal components from each receive antenna element with delays and weights that are respective functions of the multi-path transmission channels.

A method in a computer system for retrieving data from one of multiple copies of the data is provided, referred to as the data management system. The data management system receives a request identifying at least one data object to be accessed. Then, the data management system queries a metabase to locate data copies that contain the identified at least one data object, wherein the data copies are created from similar source data, and wherein for each data copy the metabase contains an indication of the availability of the copy relative to other copies. Next, the data management system determines one of the located data copies to use to access the identified at least one data object, wherein the determination is made based on the indicated availability contained in the metabase for each of the located data copies. Then, the data management system accesses the identified at least one data object using the determined one of the located data copies.

Candidates for biological activity are screened in capsules, each capsule containing a candidate, a target (which may be a molecular species or a biological cell or multiple copies of such a species or cell), and an intelligent substance. The target is one with which a successful candidate will interact to evoke a particular response in the target, and the intelligent substance is one that undergoes a transformation as a result of the response, the transformation being detectable by observation of the capsule itself. The candidate and the target are isolated from each other in the capsule until a designated point in time thereby enabling the operator to control the time interval between exposure of the target to the candidate and the observation of the capsule to determine whether or not a successful interaction has occurred and the transformation has taken place.

A system for automating the recovery of a credential store, in which client software generates a temporary key pair based on a new password, and sends client information including the user's name, the public half of the temporary key pair, and the host name of the client computer system to a server system, from which the client information is passed to a recovery process. The client software process displays a prompt indicating that the user should call a help desk. A help desk administrator verifies the user's identity and approves the user's request by causing an approval message to be sent to the recovery process. The recovery process obtains recovery information consisting of either the decryption key(s) for the credential store, or a decrypted copy of the credential store, and encrypts the recovery information using the temporary public key. The client process downloads the recovery information from the server, and decrypts it using private key of the temporary key pair. The credential store can then be decrypted using the recovery information if necessary, then re-encrypted based on the new password. The encrypted recovery information is stored on the server and re-used for a certain period of time, after which it is deleted, thus allowing multiple copies of the credential store to be conveniently recovered.

Data structures, a method, and an associated transmission system for IP fragmentation and IP reassembly on network processors in order to minimize memory allocation requirements. Frame data for IP fragmentation or reassembly on a network processor is read into buffers to which are associated various control structures. The control structures permit IP fragmentation or reassembly to be accomplished without creating multiple copies of the frame or fragments.