The invention discloses a biological sludge heating and thermal hydrolysis system and process. The system includes a material preheater, a material delivery pump, a primary steam injector, a material storage device, a feed pump, Thermal hydrolysis reactor, discharge pump, steam flasher and pressure relief valve, and secondary steam ejector for heating the biological sludge in the thermal hydrolysis reactor. The process uses the system described above for heating and thermal hydrolysis. The biological sludge heating and thermal hydrolysis system of the present invention has the advantages of good heat transfer effect, good material heating uniformity, small steam consumption, short heating time, good continuous operation stability, etc., and can be widely used to degrade biological sludge, and has the advantages of Very good application value and application prospect. The biological sludge heating and thermal hydrolysis system process of the present invention has the advantages of simple process, convenient operation, low treatment cost, high treatment efficiency, good treatment effect, etc., which is conducive to improving the utilization rate of biological sludge and expanding the application range of anaerobic digestion .