The invention discloses a piglet feed capable of enhancing disease resistance and a production method of the piglet feed. The piglet feed is prepared from the following raw materials in parts by weight: 300-350 parts of fermented soybean meal, 200-250 parts of corn flour, 100-150 parts of palm meal, 60-70 parts of rice bran powder, 30-40 parts of lentinus edodes powder, 30-40 parts of taro powder, 20-30 parts of phosphorous citric acid dreg, 20-30 parts of stipa capillata linn, 20-30 parts of peanut seedlings, 40-50 parts of hybridized pennisetum alopecuroides spreng, 30-35 parts of meat and bone meal, 10-15 parts of drumstick skin meal, 5-7 parts of red date powder, 4-6 parts of onion leaf powder, 0.5-1 part of edible essence, 20-25 parts of green plums, 7-9 parts of sliced carica papaya, 5-7 parts of sophora japonica linn flowers, 2-3 parts of lavandula angustifolia mill, 1-2 parts of latouchea fokienensis, 1-2 parts of clerodendranthus spicatus, 2-3 parts of Chinese starjasmine stem, 1-2 parts of rhizoma ligustici, 1-2 parts of cichorium intybus L leaves, 15-30 parts of a phagostimulant and a proper amount of water. By adopting the feed, the disease resistance of piglets can be enhanced and the survival rate of piglets is improved. The piglet feed has aromatic flavor, crispy taste and abundant nutrition and is capable of promoting the intake, the growth and the weight increment of the piglets while resisting diseases, and the economic benefits of pig cultivation are improved.