The invention discloses a five degree-of-freedom manipulator, and relates to a manipulator. The manipulator aims to solve the problem that no manipulator which is matched with intelligent wheelchairs and has the advantages of accurate positioning, high precision, small mass and large rigidity exists at present. A disc type driving servomotor of a paw is fixed in a mandrel of a wrist revolute joint, a wrist revolute joint connecting piece of the wrist revolute joint is fixedly connected with the upper end of an auxiliary connecting plate of a wrist joint, a connecting end of a second connecting piece of the wrist joint is fixedly connected with the upper end of a small arm, the lower-rear end of the small arm is fixedly connected with a large gear of an elbow joint, an elbow joint bearing support in the elbow joint is fixedly connected with the upper end of a big arm, the lower end of the big arm is fixedly connected with a sixth connecting piece of a shoulder joint, and the sixth connecting piece of the shoulder joint is fixedly connected with a shoulder revolute joint mandrel of a shoulder revolute joint. The manipulator can replace human arms to finish operation tasks on certain specific occasions. The manipulator has the advantages of simple structure, accurate positioning, high precision, small mass, large rigidity, full functions, safe and reliable use, simple and convenient assembly and maintenance, and lower cost.