167results about How to "No toxic reaction" patented technology

The invention provides a nano artificial dura mater with a plurality of functional layers, which comprises a structure with at least two layers; the layer facing the brain is a hydrophobic anti-adhesion electrospun layer; and the layer back to the brain is a hydrophilic nano cytoskeletal layer. The invention also provides a method for preparing the nano artificial dura mater, which comprises the following steps: preparing an electrospun solution of a hydrophobic polymer; preparing an electrospun solution of a hydrophilic polymer; preparing the prepared electrospun solution of the hydrophobic polymer into the hydrophobic anti-adhesion electrospun layer through static spinning; and preparing the hydrophilic nano cytoskeletal layer on the anti-adhesion electrospun layer from the prepared electrospun solution of the hydrophilic polymer through static spinning, receiving a membrane structure, and obtaining the nano artificial dura mater. The mechanical features of the nano artificial dura mater can meet the requirements on tensile strength and flexibility of adaptation diseases; and the nano artificial dura mater can be freely cut as required, and has wide application prospect.

The invention discloses a small and medium diameter artificial blood vessel with adjustable pressure and flow. The artificial blood vessel comprises a blood vessel wall, a blood vessel cavity is in the blood vessel wall, and a pressure and flow controller capable of adjusting the diameter of the artificial blood vessel is arranged outside the artificial blood vessel. Concave and convex grains are arranged on the blood vessel wall. The pressure and flow controller comprises a fixed shell and a control spring, wherein the fixed shell takes the shape of a cylindrical structure, and the control spring is configured to be a cylindrical structure, the control spring is arranged in the fixed shell and sleeved outside of the blood vessel wall of the artificial blood vessel, the control spring is provided with a limit spring handle for adjusting the diameter of the blood vessel, and the spring handle passes through a control frame. The fixed shell is provided with position fixing holes, and the control spring is provided with position fixing holes. The fixed shell is provided with a fastener. The pressure and flow controller comprises a mechanical pressure and flow controller, an in-vitro remote control pressure and flow controller and an in-vivo induction pressure and flow controller. The blood vessel is applicable to controlling the size of fractional flow according to an induced pressure of a hepatic portal vein after a portosystemic blood vessel is anastomosed and shunted so as to ensure the hepatic portal vein perfusion pressure required by individuals.

The present invention relates to an application of marine steroid YC-1 (24-methylene-cholesterol-3 beta, 5 alpha, 6 beta, 19-tetraol) in preparation of medicine for curing neuronal injury. It is characterized by that the oxysterol compound marine steroid YC-1 extracted from lip-softened coral of the Nansha Islands has protection action for several kinds of neuronal injuries, under the condition of effective protection dosage it does not produce toxic reaction. Said invention adopts a chemical synthesis method to make large-scale production.

The invention relates to a preparation method and new application of a polyinosinic preparation. Kanamycin and calcium ions are added on the basis of polyinosinic, so that the stability of polyinosinic double-stranded ribonucleic acid (RNA) is enhanced. Animal experiment results show that a polyinosinic complex has the effect of inhibiting tumor growth.

The gout resisting Chinese medicine composition is prepared with alcohol extract of rhubarb in 90 weight portions and tetrandra root in 30 weight portions, water extract of plantain seed in 60 weight portions, oriental water plantain in 60 weight portions and achyranthes root in 60 weight portions, and supplementary material in proper amount. The preparation process includes the steps of: weighing material in certain proportion; preparing tetrandra root extractum through crushing, twice alcohol reflux extraction, etc; preparing rhubarb filtrate through alcohol reflux extraction, etc; preparing mixed filtrate of plantain seed, oriental water plantain and achyranthes root through twice decoctions, etc; mixing the rhubarb filtrate and the mixed filtrate, decompression concentration and drying to obtain mixed extractum; mixing tetrandra root extractum with the mixed extractum and supplementary material, pelletizing, tabletting and encapsulating.