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Auxiliary treating medicine for lung cancer in late stage

A technology for adjuvant therapy and drugs, which is applied in drug combinations, antineoplastic drugs, pharmaceutical formulations, etc., and can solve problems such as undisclosed raw material drug dosage ratio preparation methods and other problems.

Active Publication Date: 2006-05-17
津药达仁堂集团股份有限公司达仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The dosage ratio and preparation method of raw materials have not yet been disclosed. There are various methods of treating advanced lung cancer in traditional Chinese medicine, but it is still necessary to screen and formulate prescriptions on the basis of modern pharmacology and biological activity research of traditional Chinese medicine, and develop new Chinese patent medicines with good curative effect Easy for patients to take

Method used

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  • Auxiliary treating medicine for lung cancer in late stage

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0360] Raw material prescription:

[0361] Astragalus 250g, Dangshen 125g, North Ginseng 100g

[0362] Ophiopogon japonicus 75g Agrimony 125g Boxing ginseng 100g

[0363] Patrinia 83.3g Hedyotis diffusa 166.7g Chuan Fritillaria 75g

[0364] Aster 75g Bellflower 75g Bitter almond 100g Licorice 50g

[0365] The preparation method is as follows:

[0366] In the GMP purification workshop, add Codonopsis pilosula, Patrinia, Hedyotis diffusa, Campanulaceae, and Fritillaria 95% ethanol to 5 times the amount of the above thirteen flavors, heat and extract for 1.5 hours, and filter to obtain the alcohol extract and residue , the alcohol extraction solution recovers ethanol to obtain the extract to a relative density of 1.35-1.40 (60°C); the remaining bitter almonds and other eight-flavored medicines and alcohol extraction residues are decocted twice with 7 times the amount of water, the first time is 1.5 hours, and the second time For 1 hour, filter, combine the filtrates twice, he...

Embodiment 2

[0369] Raw material prescription:

[0370] Astragalus 250g, Codonopsis 125g, Northern Radix Ginseng 100g, Ophiopogon japonicus 75g

[0371] Agrimony 125g Fist Ginseng 100g Patrinia 83.3g

[0372] Hedyotis diffusa 166.7g Fritillaria 75g Aster 75g Bellflower 75g

[0373] Bitter almond 100g Licorice 50g

[0374] The preparation method is as follows:

[0375] In the GMP purification workshop, for the above thirteen flavors, add Codonopsis pilosula, Patrinia, Hedyotis diffusa, Campanulaceae, and Fritillaria quinquefolium with five times the amount of 95% ethanol, heat and extract for 1.5 hours, and filter to obtain the alcohol extract and residue① , recover ethanol from the alcohol extract to obtain an extract to a relative density of 1.35-1.40 (60°C), add 5 times the amount of water, stir well, let it stand for 24 hours to precipitate, and filter with suction to obtain the precipitate ②; the rest of bitter almonds and other eight herbs Add 7 times the amount of water to the al...

Embodiment 3

[0377] Raw material prescription:

[0378] Astragalus 250g, Codonopsis 125g, Northern Radix Ginseng 100g, Ophiopogon japonicus 75g

[0379] Agrimony 125g Fist Ginseng 100g Patrinia 83.3g

[0380] Hedyotis diffusa 166.7g Fritillaria 75g Aster 75g

[0381] Bellflower 75g Bitter almond 100g Licorice 50g

[0382] The preparation method is as follows:

[0383]In the GMP purification workshop, for the above thirteen flavors, add Codonopsis pilosula, Patrinia, Hedyotis diffusa, Campanulaceae, and Fritillaria quinquefolium with five times the amount of 95% ethanol, heat and extract for 1.5 hours, and filter to obtain the alcohol extract and residue① , recover ethanol from the alcohol extract to obtain an extract to a relative density of 1.35-1.40 (60°C), add 5 times the amount of water, stir well, let it stand for 24 hours to precipitate, and filter with suction to obtain the precipitate ②; the rest of bitter almonds and other eight herbs Add 7 times the amount of water to the alc...

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PUM

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Abstract

The present invention relates to technology of medicinal preparation with component from plant in unknown structure, and is especially medicine comprising extract of 13 kinds of Chinese medicinal materials, including astragalus root, Dangshen, root of straight ladybell, ophiopogon root, arimonia herb. The medicine has reasonable recipe, modern preparation process, and the functions of benefiting vital energy, nourishing Yin, clearing away heat and toxic material, eliminating phlegm and relieving cough. It is suitable for the auxiliary treatment of vital energy and Yin deficiency and Yin deficiency internal heat type lung cancer in late stage, and has also high curative effect on shortness of breath, hypodynamia, cough, etc.

Description

technical field [0001] The present invention relates to the technical field of medical preparations containing reaction products of unknown structure derived from plants, in particular a kind of adjuvant therapy drug for advanced lung cancer made from extracts of Chinese herbal medicines and its preparation method Background technique [0002] Clinically, patients with advanced lung cancer often have symptoms such as shortness of breath, fatigue, cough, hemoptysis, and chest pain. An adjuvant drug for advanced lung cancer—the drug name "Yifei Qinghua Ointment" is also known as "Lung Liu Ping Ointment" for Qi and Yin Adjuvant therapy for advanced lung cancer of dual-deficiency and yin-deficiency internal-heat type. Drugs have been reported in the literature, and currently there are the following: [0003] 1. The newly edited national Chinese patent medicine, July 2002, 1st edition, page 1016 included "Yifei Qinghua Paste", which reported that the components were composed of:...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/06A61K9/16A61K9/20A61K9/48A61P35/00
Inventor 徐晓阳
Owner 津药达仁堂集团股份有限公司达仁堂制药厂
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