The invention discloses a multifunctional base plate based on the PCB technology and a manufacturing method thereof. The multifunctional base plate comprises a multilevel interconnection base plate, a glass base plate and an optical waveguide layer. An upper-layer graph is etched on the upper surface of the glass base plate, and a del-shaped reflector is arranged in the optical waveguide layer. A lower-layer graph is etched on the lower surface of the optical waveguide layer, and the upper-layer graph and the lower-layer graph are communicated with a transmission channel of the multilevel interconnection base plate through through holes vertically formed in the glass base plate, the multilevel interconnection base plate, and the optical waveguide layer in an embedded mode. The manufacturing method includes the steps of pressing the glass base plate and the optical waveguide layer, cutting the reflector, manufacturing the through holes, hole plating copper and face copper, etching the graphs and bonding pads and installing devices. The multifunctional base plate based on the PCB technology and the manufacturing method thereof can solve the problem of low losses of high-frequency transmission, so that the optical interconnection transmission capacity is high, the interconnection density is high, and the anti-electromagnetic interference capability is high; the multifunctional base plate based on the PCB technology and the manufacturing method thereof are suitable for millimeter wave interconnection, the manufacturing technology is simple, cost is low, and the multifunctional base plate based on the PCB technology and the manufacturing method thereof are also suitable for application with the sealing requirement.