The invention discloses a radiation cross-linked polyetheretherketone extruded insulation aluminum alloy round winding wire, which consists of an aluminum alloy round wire conductor, a first insulation layer and a second insulation layer. Meanwhile, the invention discloses a process method for the radiation cross-linked polyetheretherketone extruded insulation aluminum alloy round winding wire. The process method comprises the following steps of: preheating the conductor, performing double-layer extrusion cladding to make the first insulation layer and the second insulation layer arranged on an aluminum alloy round wire, performing radiation cross-linking by using an electron accelerator, and cooling the insulation layers in a section gradient decreasing cooling mode. The aluminum alloy winding wire prepared by the technical scheme does not react with other common chemical medicines, has corrosion resistance close to that of nickel steel, is halogen-free and non-toxic, has high flame resistance, completely meets the requirement of related electric equipment such as a large transformer, a motor, an electromagnet and the like on the high electric property, mechanical property, high-temperature resistance, wear resistance, corrosion resistance, solvent resistance, hydrolysis resistance, scratch resistance, peeling resistance, flame retardance, insulation stability and long-life performance of the winding wire, ensures that large equipment is lightweight, saves copper resources, and is low-carbon and environment-friendly.