356results about How to "Desirable property" patented technology

A multifunctional membrane is provided. The multifunctional membrane is suitable for use in an analyte sensor. In a particular application, the multifunctional membrane may be used in connection with an amperometric biosensor, such as a transcutaneous amperometric biosensor. Some functions of the membrane are associated with properties of membrane itself, which is comprised of crosslinked polymers containing heterocyclic nitrogen groups. For example, the membrane, by virtue of its polymeric composition, may regulate the flux of an analyte to a sensor. Such regulation generally improves the kinetic performance of the sensor over a broad range of analyte concentration. Other functions of the membrane are associated with functional components, such as a superoxide-dismutating / catalase catalyst, either in the form of an enzyme or an enzyme mimic, that can be bound to the scaffold provided by the membrane. The effect of any such enzyme or enzyme mimic is to lower the concentration of a metabolite, such as superoxide and / or hydrogen peroxide, in the immediate vicinity of the sensing layer of the biosensor. Lowering the concentrations of such metabolites, which are generally deleterious to the function of the sensor, generally protects or enhances biosensor integrity and performance. The membrane is thus an important tool for use in connection with analyte sensors, amperometric sensors, biosensors, and particularly, transcutaneous biosensors. A membrane-covered sensor and a method for making same are also provided.

Nitrogen-containing phase-stabilized films, methods of forming phase-stabilized films, and structures and devices including the phase-stabilized films are disclosed. The phase-stabilized films include a matrix material and a phase stabilizer, which provides a morphologically stabilizing effect to a matrix material within the films. The phase-stabilized films may be used as, for example, gate electrodes and similar films in microelectronic devices.

A multifunctional membrane is provided. The multifunctional membrane is suitable for use in an analyte sensor. In a particular application, the multifunctional membrane may be used in connection with an amperometric biosensor, such as a transcutaneous amperometric biosensor. Some functions of the membrane are associated with properties of membrane itself, which is comprised of crosslinked polymers containing heterocyclic nitrogen groups. For example, the membrane, by virtue of its polymeric composition, may regulate the flux of an analyte to a sensor. Such regulation generally improves the kinetic performance of the sensor over a broad range of analyte concentration. Other functions of the membrane are associated with functional components, such as a superoxide-dismutating / catalase catalyst, either in the form of an enzyme or an enzyme mimic, that can be bound to the scaffold provided by the membrane. The effect of any such enzyme or enzyme mimic is to lower the concentration of a metabolite, such as superoxide and / or hydrogen peroxide, in the immediate vicinity of the sensing layer of the biosensor. Lowering the concentrations of such metabolites, which are generally deleterious to the function of the sensor, generally protects or enhances biosensor integrity and performance. The membrane is thus an important tool for use in connection with analyte sensors, amperometric sensors, biosensors, and particularly, transcutaneous biosensors. A membrane-covered sensor and a method for making same are also provided.

Chemical vapor deposition is performed using a plurality of expanding thermal plasma generating means to produce a coating on a substrate, such as a thermoplastic and especially a polycarbonate substrate. The substrate is preferably moved past the generating means. Included are methods which coat both sides of the substrate or which employ multiple sets of generating means, either in a single deposition chamber or in a plurality of chambers for deposition of successive coatings. The substrate surfaces spaced from the axes of the generating means are preferably heated to promote coating uniformity.

A layer of fluoropolymer fine fiber can be made. The fine fiber can be made by electrospinning from a solvent or a solvent blend. The layers of the invention are useful in general filtration of fluid streams including gaseous and liquid streams. The fine fiber layers are also useful as hydrophobic filtration layers that can be used to separate water from a hydrocarbon stream.

Disclosed herein is a polymeric material comprising a conductive polymer substantially homogeneously distributed within a hydrogel. Also disclosed are methods for making the polymeric material and uses for the polymeric material.

The present invention relates to a method for the comparative assessment of the level of specific nucleic acid sequences in samples derived from different sources. More specifically, the invention relates to a method using oligonucleotides covalently linked to a solid support, such as beads, to isolate specific labeled nucleic acid sequences from complex mixtures. The methods disclosed allow quantitative comparisons of the amount of nucleic acid of defined sequence in a plurality of different samples of nucleic acid, e.g., from different cells or tissues or from genetic libraries. Nucleic acids from the samples are labeled in such a fashion that the signals can be distinguished and compared following hybridization to the oligonucleotides on the beads. According to the invention, the solid supports with the hybridized nucleic acid may be retrieved, and the target nucleic acid eluted and analyzed. Furthermore, the invention provides a method for tagging individual clones from a cDNA library such that they can be identified uniquely and retrieved by hybridization to specific beads.

A fisheye lens with a field angle of at least one hundred sixty degrees is formed of two lens groups, arranged in order from the object side, as follows: a first lens group having negative refractive power and a second lens group having positive refractive power. The first lens group includes, arranged in order from the object side, two lens elements, each having negative refractive power and a meniscus shape with the convex surface on the object side, a lens element having negative refractive power with a concave surface on the image side, and two lens elements of opposite refractive powers. The second lens group includes, arranged in order from the object side, two lens elements of opposite refractive powers, a stop, and two lens elements of opposite refractive powers. The fisheye lens preferably satisfies specified conditions related to spacings of lens surfaces and to distortion characteristics of the fisheye lens.

Provided herein are blends oils or fatty acids comprising more than 50% medium chain fatty acids, or the fatty acid alkyl esters thereof, and having low melting points. Such blends are useful as a fuel or as a starting material for the production of, for example, a biodiesel. Also provided genetically altered or modified plants, modified such that the amount of medium chain fatty acids generated by the plant are increased. Further provided is a method of predicting the melting point of a blend of fatty acid methyl esters and the use of such a method for identifying blends suitable for use as, for example, a biodiesel.

Channel depth in a field effect transistor is limited by an intra-layer structure including a discontinuous film or layer formed within a layer or substrate of semiconductor material. Channel depth can thus be controlled much in the manner of SOI or UT-SOI technology but with less expensive substrates and greater flexibility of channel depth control while avoiding floating body effects characteristic of SOI technology. The profile or cross-sectional shape of the discontinuous film may be controlled to an ogee or staircase shape to improve short channel effects and reduce source / drain and extension resistance without increase of capacitance. Materials for the discontinuous film may also be chosen to impose stress on the transistor channel from within the substrate or layer and provide increased levels of such stress to increase carrier mobility. Carrier mobility may be increased in combination with other meritorious effects.

Composite materials having at least one of the following desirable properties is described. Such properties include: rigidity, printability, water-proofness, pliability, recyclable, thermochromic, antimicrobial, electrically conductive, compostable or biodegradability. The composite includes a filler-containing layer and a fiber-containing layer substantially coupled together continuously across the at least one surface of the layers. These composites maybe useful in various markets including, but not limited to, construction, packaging, shipping, consumer products and medical packaging. The inventive composites provide, advantages such as reduction of environmental footprint, improved mechanical properties, usefulness / cost ratio, reduction in material costs compared to prior art, and cosmetic performance are embodied in the present invention.

The present invention relates to the delivery of drug amines through an inhalation route. Specifically, it relates to aerosols containing drug amines that are used in inhalation therapy. In one aspect of the present invention, a method of delivering an amine drug in an aerosol form is provided. The method comprises: a) heating a coating, which includes an amine drug salt on a substrate contained in a device to a temperature sufficient to volatilize the amine drug from the coating, b) by said heating, forming an amine drug vapor, and c) during said heating, drawing air through said device, condensing said vapor to form aerosol particles containing less than 10% degradation products of the compound.

A multifunctional polymer comprising a polymeric chain having chromophore groups and cross-linking sites is suitable as a resist material and especially as the underlayer for bilayer and top surface imaging strategies. The multifunctional polymer can function as an antireflective coating, planarizing layer or etch resistant hard mask.

Disclosed is a variable voltage protection device for electronic devices which in one aspect comprises a thin layer of neat dielectric polymer or glass positioned between a ground plane and an electrical conductor for overvoltage protection, wherein the neat polymer or glass layer does not include the presence of conductive or semiconductive particles. Also disclosed is the combination of the neat dielectric polymer or glass thin layer positioned on a conventional variable voltage protection material comprising a binder containing conductive or semiconductive particles. A multi-layer variable voltage protection component is disclosed comprising three layers of overvoltage protection material wherein the outer two layers contain a lower percentage of conductive or semiconductive particles and wherein the inner layer contains a higher percentage of conductive or semiconductive particles. The multi-layer component can optionally be used in combination with the neat dielectric polymer or glass layer and can optionally have interposed metal layers. A method is disclosed for dispersing insulative particles and conductive or semiconductive particles in a binder using a volatile solvent for dispersement of the insulative particles and the conductive or semiconductive particles before mixing with the binder.

An orthopedic implant comprising a substrate material adapted to provide the orthopedic implant. The implant has a primary friction area located on or integral with the substrate material. The primary friction area defining an engagement surface having a primary frictional feature. A secondary friction area is located on or integral with the engagement surface and defining a second frictional feature. The primary friction area and the secondary friction area defining a friction interface zone between the orthopedic implant and at least one bone. The secondary friction area increases a friction of the engagement surface and modulus of elasticity to enhance the frictional engagement between the engagement surface and the at least one bone.

The present invention provides purified, corn tassel-derived polynucleotides (cdps) which encode corn tassel-derived polypeptides (CDPs). The invention also provides for the use of cdps or their complements, oligonucleotides, or fragments in methods for determining altered gene expression, to recover regulatory elements, and to follow inheritance of desirable characteristics through hybrid breeding programs. The invention further provides for vectors and host cells containing cdps for the expression of CDPs. The invention additionally provides for (i) use of isolated and purified CDPs to induce antibodies and to screen libraries of compounds and (ii) use of anti-CDP antibodies in diagnostic assays.

The present invention relates to binding compounds specific for BTLA and uses thereof. More specifically, the invention relates to fully human antibodies that recognize human BTLA and modulate its activity in cancer, inflammatory, and autoimmune disorders.

Branched crystalline polypropylene compositions and methods for the preparation of branched crystalline polypropylene compositions are provided. For example, described herein is a process of preparing a branched crystalline polypropylene composition that includes combining two or more different metallocene catalyst compounds with a polymerization medium that includes propylene, for a time sufficient to provide branched crystalline polypropylene that has from 0.0 wt % to 2.0 wt % ethylene and a heat of fusion of 70 J / g or more.

Thermally divisible multicomponent fibers having at least a first component including an elastomeric polymer and at least a second component including a non-elastomeric polymer. The multicomponent fibers are useful in the manufacture of nonwoven structures, and in particular nonwoven structures used as synthetic suede and filtration media.

Oral medicament delivery system comprising a pharmaceutical composition comprising a flexible matrix, said matrix formed of a plurality of fibers comprising a collagen-based carrier and a medicament, the composition orally dissolvable to deliver a unit dose of the medicament to a patient. The flexible composition can be dose titrated and co-administered with a second pharmaceutical formulation.

The present invention provides a polymer alloy including from about 40% to about 75% by weight of at least one polyamide, from about 10% to about 50% by weight polypropylene, from about 0.01% to about 1.0% by weight of at least one block copolymer including a vinyl aromatic monomer and a conjugated diene, and also includes an unsaturated dicarboxylic reagent, from about 0.1% to about 5.0% by weight of at least one block copolymer or terpolymer, wherein the terpolymer may have an unsaturated dicarboxylic reagent grafted thereto, from about 0.01% to about 7.5% of a compatibilizing agent, and from about 5% to about 50% by weight of a filler. The alloy of the present invention exhibits improved knitline strength and improved drop impact results compared with prior art fiberglass-reinforced nylon blends.

Chemical vapor deposition is performed using a plurality of expanding thermal plasma generating means to produce a coating on a substrate, such as a thermoplastic and especially a polycarbonate substrate. The substrate is preferably moved past the generating means. Included are methods which coat both sides of the substrate or which employ multiple sets of generating means, either in a single deposition chamber or in a plurality of chambers for deposition of successive coatings. The substrate surfaces spaced from the axes of the generating means are preferably heated to promote coating uniformity.

A highly compact inductor formed on opposite faces of a dielectric substrate. Sets of parallel spaced conductive traces formed on the opposite faces of the substrate are interconnected by metallized vias through the substrate, in such a way as to form a continuous spiral conductive path. The inductor is preferably formed as two closely adjacent segments, each with conductive traces on each face of the substrate and each having metallized vias interconnecting the conductive traces. The segments are electrically connected in series and produce a magnetic field that extends through each segment in opposite directions and is closely coupled from one segment to the other. The inductor is, therefore, electromagnetically similar to a wire-wound toroidal inductor, providing high inductance and contourable Q values, but is highly compact, especially in the z-axis direction normal to the substrate.

Polymeric ionic gels of ionic liquids having melting points below about 100° C. that are formed by the reaction of a heterocyclic amine with about 2.8 and about 3.2 moles of anhydrous hydrogen fluoride per mole of amine nitrogen. Electrochemical devices having non-aqueous electrolytes containing the ionic liquids and polymeric ionic gels are also disclosed.

A light source for emitting emitted light having an SPD comprising: (a) a plurality of light emitters including at least one violet solid-state emitter; (b) at least one phosphor; wherein said light emitters and said at least one phosphor being configured such that: at least 25% of the power within the SPD is in the range 390-420 nm, and the emitted light has a chromaticity which is within a Duv distance of less than 5 points from the Planckian locus.

A silica cement blend having an insulating, fire retarding and high temperature characteristic capable of withstanding temperatures ranging from ambient to greater than 40000 F without degradation of the concrete structure. In addition to its high temperature capabilities the blend can be produced as ultra light weight to heavy weight concrete. The silica based mixture when added to cementitious materials such as Portland cement, Class C Fly Ash, silica fume and other cementitious materials. Presented also are methods for reducing fire damage by coating interior / exterior walls, ceiling, and roofs of a building with a water based latex coating containing a fire retardant material and low heat conductivity silicas. Methods for painting internal / external walls, ceilings, and roof are also presented. This coating retains thermal blocking properties comprised of processed, expanded and / or finely milled, pyrogenic silicas and micro spheres in combination of but not limited to, one, two or more component water based polymer / copolymer latex binders and a water born fluoropolymer emulsion. The combined properties of these elements create a coating similar to paint with a high level of thermatic resistance which slows the composition break-down from fire, extreme temperatures, and restricts the thermal conductivity which helps to preserve the integrity of the substructure or underlying materials. The properties of this coating reduce or slow the potential of catastrophic fire by retarding flashover and protecting the under structure; which in turn assist fire fighters and rescue personnel by helping to retard the potential of a catastrophic fire.

Electronics packages having a primary metallic material, such as a titanium metallic material, metallurgically bonded to one or more secondary regions within the primary metallic material, the composite regions having desirable thermal conductivity properties and having a coefficient of thermal expansion ("CTE") that generally matches the CTE of the primary metallic material are provided. Electronics packages comprising titanium having heat sinks comprising a metal matrix material such as aluminum silicon carbide or a composite metallic structure such as titanium aluminide / copper, are described. Methods for manufacturing electronics packages having a composite structure are also disclosed.

Colloidal nanocrystal quantum dots comprising an inner core having an average diameter of at least 1.5 nm and an outer shell, where said outer shell comprises multiple monolayers, wherein at least 30% of the quantum dots have an on-time fraction of 0.80 or greater under continuous excitation conditions for a period of time of at least 10 minutes.