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43results about How to "Broaden raw material channels" patented technology

Cortex periplocae anti-tumor effective component extractive as well as preparation method and application thereof

The invention discloses a cortex periplocae anti-tumor effective component extractive, which is prepared by the following steps of: crushing cortex periplocae; extracting under heating by utilizing water at 90-100 DEG C, concentrating an extracting solution, carrying out alcohol precipitation, centrifuging, removing sediment and concentrating under reduced pressure to remove ethanol to obtain an extracting solution; or extracting under heating by utilizing ethanol with the concentration of 40-95% in a water bath of 80 DEG C, cooling and centrifuging, and concentrating to remove ethanol to obtain an extracting solution; sequentially extracting the extracting solution by utilizing ethyl acetate and water saturated n-butyl alcohol; subjecting a n-butyl alcohol extracted part to silica gel column separation, wherein a diluting agent is dichloromethane-methanol with the different volume ratios; collecting a diluting solution with the volume ratio of dichloromethane to methanol of 10: 1; and recycling an organic solvent to obtain the cortex periplocae anti-tumor effective component extractive. According to the cortex periplocae anti-tumor effective component extractive disclosed by the invention, in an in-vitro cellular toxicity test, the part has the obvious effects of inhibiting U251 (glioma cells), HepG2 (hepatoma carcinoma cells), SGC (stomach carcinoma cells), mcf-7 (human breast cancer cells) and SCLC (small cell lung cancer cells), and can be used for preparing an anti-tumor medicine. The invention discloses a preparation method of the cortex periplocae anti-tumor effective component extractive.
Owner:JIANGSU UNIV

Effective parts of willow herb and preparing method and application tehreof

The invention discloses the effective parts of willow herb and the preparing method and application thereof. The invention belongs to the technical field of plant extract. The method comprises of the steps of selecting the mixture of one or two extracts from the ethyl acetate part and normal butyl alcohol part of willow herb at any weight ratio. Crushing the willow herb and adding 65%-95% (volume) ethanol solution for extraction, concentrating and drying the extracting solution to obtain the extract; adding distilled water for dispersion to obtain extract dispersion, then respectively using petroleum ether, ethyl acetate and normal butyl alcohol as the solvent to extract the extract dispersion, making the solvent volatilize to obtain the ethyl acetate part and normal butyl alcohol part of willow herb. Effective parts of willow herb can be used to prepare anti-HBV, anti-H1N1 A virus drugs, with good effect to resist hepatitis B and influenza A virus.
Owner:QINGHAI UNIV FOR NATITIES

Effective part of Corydalis conspersa as well as preparation method and application of effective part

The invention provides an effective part of Corydalis conspersa as well as a preparation method and an application of the effective part and belongs to the technical field of plant extracts. The effective part of the Corydalis conspersa is selected from one of an ethyl acetate extract of the Corydalis conspersa, an n-butyl alcohol extract of the Corydalis conspersa and an aqueous extraction extract of the Corydalis conspersa or a mixture of two or more of the extracts of the Corydalis conspersa in any mass ratio. The preparation method comprises steps as follows: the herb of the Corydalis conspersa is ground, an ethanol solution with volume percentage concentration being 65%-95% is added for reflux extraction, an obtained extracting solution is concentrated and dried, and extractum is obtained; distilled water is added to the extractum, the extractum is dispersed, an extractum dispersion liquid is obtained and is extracted with petroleum ether, ethyl acetate and n-butyl alcohol as solvents sequentially, and after solvents are volatilized, the ethyl acetate extract of the Corydalis conspersa and the n-butyl alcohol extract of the Corydalis conspersa are obtained; the extractum dispersion liquid after extraction is concentrated and dried, and the aqueous extraction extract of the Corydalis conspersa is obtained. According to the application of the effective part of the Corydalis conspersa in preparation of drugs for inhibiting CDC25 enzyme and HDAC1 enzyme, the effective part of the Corydalis conspersa can be used for preparing antitumor drugs.
Owner:QINGHAI UNIV FOR NATITIES

Saussurea-obvallata effective part and preparing method and application thereof

The invention discloses a saussurea-obvallata effective part and a preparing method and application thereof, and belongs to the technical field of plant extract. The saussurea-obvallata effective part is selected from the mixture of any mass ratio of one or two above of a saussurea-obvallata petroleum ether part, a saussurea-obvallata ethyl acetate part, a saussurea-obvallata n-butyl alcohol part and a saussurea-obvallata aqueous phase extraction part. The preparing method includes the steps that saussurea-obvallata whole plant is smashed, an ethanol solution with the mass percent concentration of 65% to 95% is added and subjected to reflux extraction, the obtained extracted liquid is concentrated and dried, and extract is obtained; the extract is dispersed in distilled water, extract dispersion liquid is obtained, petroleum ether, ethyl acetate and n-butyl alcohol are sequentially used as a solvent to extract the extract dispersion liquid, and after the solvent is volatilized, the saussurea-obvallata petroleum ether part, the saussurea-obvallata ethyl acetate part and the saussurea-obvallata n-butyl alcohol part are obtained; the extracted extract dispersion liquid is concentrated and dried, and the saussurea-obvallata aqueous phase extraction part is obtained. The saussurea-obvallata effective part has an application to preparing medicine for inhibiting a HDAC1 enzyme, and can be used for preparing antitumor medicine.
Owner:QINGHAI UNIV FOR NATITIES

Tinospora sinensis HDAC1 enzyme inhibition effective part, as well as preparation method and application thereof

The invention discloses a tinospora sinensis HDAC1 enzyme inhibition effective part, as well as a preparation method and application thereof, and belongs to the technical field of plant extracts. The corydalis pygmaea effective part is one of a corydalis pygmaea petroleum ether part and a corydalis pygmaea aqueous extraction part, or a mixture of more than two of a corydalis pygmaea petroleum ether part, a corydalis pygmaea ethyl acetate part, a corydalis pygmaea n-butyl alcohol part and a corydalis pygmaea aqueous extraction part in an arbitrary mass ratio. The preparation method comprises the following steps of: grinding corydalis pygmaea, refluxing and extracting with an ethanol solution having a volume percentage concentration of 65-95 percent, concentrating and drying the extract to obtain an extract; dispersing the extract with distilled water to obtain an extract dispersant, extracting the extract dispersant sequentially with petroleum ether, ethyl acetate and n-butyl alcohol, and volatilizing a solvent to obtain a corydalis pygmaea petroleum ether part, a corydalis pygmaea ethyl acetate part and a corydalis pygmaea n-butyl alcohol part; and concentrating and drying the extracted extract dispersant to obtain a corydalis pygmaea water-phase extraction part. The corydalis pygmaea HDAC1 enzyme inhibition effective part can be applied to preparation of medicines for inhibiting HDAC1 enzyme, and can be used for preparing anti-tumor medicines.
Owner:QINGHAI UNIV FOR NATITIES

Hypecoum leptocarpum effective part as well as preparation method and application thereof

The invention discloses a hypecoum leptocarpum effective part as well as a preparation method and application thereof, belonging to the technical field of plant extract. The hypecoum leptocarpum effective part is selected from one or mixture of over two of a hypecoum leptocarpum n-butyl alcohol part, a hypecoum leptocarpum water-phase extraction part and a hypecoum leptocarpum chloroform part in any mass ratio. The preparation method comprises the following steps: grinding the hypecoum leptocarpum, adding a 65-95% ethanol solution by mass and performing reflux extraction; concentrating and drying to obtain extract; adding distilled water into the extract for dispersion; sequentially extracting with petroleum ether, ethyl acetate and n-butyl alcohol; volatilizing to remove solvents to obtain the hypecoum leptocarpum n-butyl alcohol part; concentrating and drying the extract dispersion liquid after extraction to obtain the hypecoum leptocarpum water-phase extraction part; and adding a 2% hydrochloric acid aqueous solution by mass into the extract for extraction, adjusting the pH value to 9-10, extracting repeatedly with chloroform, and volatilizing to remove solvents to obtain the hypecoum leptocarpum chloroform part. The application of the hypecoum leptocarpum effective part disclosed by the invention in preparing medicines for inhibiting HDAC1 enzymes can be used for preparing anti-tumor medicines.
Owner:QINGHAI UNIV FOR NATITIES

Coal gangue-based quick-hardening cementing material and preparation method thereof

The invention relates to a coal gangue-based quick-hardening cementing material and a preparation method thereof, the coal gangue-based quick-hardening cementing material contains tetracalcium sulphoaluminate, tricalcium silicate, dicalcium silicate and iron, part of SiO2 in coal gangue is calcined into tricalcium silicate, the coal gangue provides aluminum and siliceous, carbide slag provides calcium, gypsum, steel slag, fluorite, chromium slag and barite are added, and clinker is sintered at a low calcination temperature, and a certain amount of gypsum, limestone and volcanic ash are doped to prepare the quick-hardening cementing material. Part of SiO2 in the coal gangue is calcined into tricalcium silicate to enhance the early strength of the tricalcium silicate so that the material can be used for winter construction, emergency repair construction and the like; in the clinker calcination process, fluorite, chromium slag, barite and other mineralizers are added, and dicalcium silicate in steel slag has a nucleation effect so that the cementing material has a lower calcination temperature than traditional Portland cement, CO2 emission can be reduced, and environmental protection is facilitated.
Owner:INNER MONGOLIA UNIV OF TECH

Agaricus gennadii HDAC1 enzyme inhibition effective part and preparation method and application

The invention provides an agaricus gennadii HDAC1 enzyme inhibition effective part and a preparation method and application and belongs to the technical field of plant extracts. The effective part is selected from a mixture of one or more of an agaricus gennadii petroleum ether part, an agaricus gennadii ethyl acetate part, an agaricus gennadii n-butyl alcohol part and an agaricus gennadii aqueous phase extraction part according to any mass ratio. Agaricus gennadii is smashed, an ethyl alcohol solution with the volume percentage concentration being 65-95% is added for reflux extraction, and an obtained extracting solution is concentrated and dried to obtain an extract; the extract is added into distilled water to be dispersed, an extract dispersion solution is obtained and extracted by sequentially using petroleum ether, ethyl acetate and n-butyl alcohol as solvents, and the agaricus gennadii petroleum ether part, the agaricus gennadii ethyl acetate part and the agaricus gennadii n-butyl alcohol part are obtained after the solvents are removed through volatilization; the remaining extract dispersion solution obtained after extraction is concentrated and dried, and the agaricus gennadii aqueous phase extraction part is obtained. The agaricus gennadii HDAC1 enzyme inhibition effective part is applied to preparing HDAC1 enzyme inhibition medicine and can be used for preparing anti-tumor medicine.
Owner:QINGHAI UNIV FOR NATITIES

Gentiana veitchiorum effective part and preparation method and application thereof

The invention discloses a gentiana veitchiorum effective part and a preparation method and application thereof, and belongs to the technical field of plant extracts. The effective part is selected from one of or a mixture of two or more of, by any mass ratio, a gentiana veitchiorum petroleum ether part, a gentiana veitchiorum ethyl acetate part, a gentiana veitchiorum n-butanol part and a gentiana veitchiorum aqueous phase extraction part. A whole gentiana veitchiorum plant is smashed, an ethyl alcohol solution with the volume percentage concentration being 65-95% is added for reflux extraction, and the obtained concentrated solution is concentrated and the concentrate is dried to obtain an extract; distilled water is added to the extract for dispersion to obtain an extract dispersion solution, petroleum ether, ethyl acetate and n-butanol sequentially serve as solvents to extract the extract dispersion solution, and the gentiana veitchiorum petroleum ether part, the gentiana veitchiorum ethyl acetate part and the gentiana veitchiorum n-butanol part are obtained after the solvents are volatilized; the extracted extract dispersion solution is concentrated and the concentrated material is dried to obtain the gentiana veitchiorum aqueous phase extraction part. The gentiana veitchiorum effective part is applied to preparing medicine for inhibiting CDC25 enzyme, and can be used for preparing anti-tumor medicine.
Owner:QINGHAI UNIV FOR NATITIES

Extract of effective components of antineoplastic gallnut as well as preparation method and application thereof

The invention provides an extract of effective components of antineoplastic gallnut. The extract is prepared from the following steps in sequence: drying the gallnut: crushing the dried gallnut; adding petroleum ether to remove the oil; drying in the air; carrying out water extraction and alcohol precipitation; evaporating to remove ethanol from the filtrate; extracting by diethyl ether; and concentrating the extractive liquid under diethyl ether, thus obtaining the extract of the effective components of antineoplastic gallnut. As the study shown, the extract of the effective components has the activity of inhibiting the growth of U251 (glioma cells) outside the body, so that the extract can be applied to preparation and development of antineoplastic medicines. The invention also discloses a preparation method of the extract.
Owner:JIANGSU UNIV

Shiitake mushroom-salmon caviar formula

The invention discloses a shiitake mushroom-salmon caviar formula. The shiitake mushroom-salmon caviar formula is prepared from the following raw materials: salmon roes, shiitake mushrooms, perilla frutescens, fermented soya beans, laurel leaves, cloves, honey and cooking wine. The shiitake mushroom-salmon caviar formula is composed of natural food materials, so that the prepared shiitake mushroom-salmon caviar is healthy, health-caring and refreshing in taste. The caviar contains trace elements, mineral salt, protein, amino acid and recombinant essential fatty acid needed by the skin, so that the caviar is capable of effectively moistening and nourishing the skin, as well as ensuring the skin fine, smooth, bright and clean. The shiitake mushrooms contain the components, including polysaccharides, vitamin B1, vitamin B2, calcium, phosphorus, iron and so on; and the shiitake mushrooms have the functions of reducing cholesterol, resisting cancer and enhancing body immunity.
Owner:刘彬

Corydalis pygmaea effective part, as well as preparation method and application thereof

The invention discloses a corydalis pygmaea effective part, as well as a preparation method and application thereof, and belongs to the technical field of a plant extract. The corydalis pygmaea effective part is mixture of one or more than one of a corydalis pygmaea petroleum ether part, a corydalis pygmaea ethyl acetate part and a corydalis pygmaea aqueous extraction part in an arbitrary mass ratio. The preparation method comprises the following steps: grinding whole grass of corydalis pygmaea, refluxing and extracting with an ethanol solution having a volume percentage concentration of 65-95 percent, concentrating and drying the extract to obtain an extract; dispersing the extract with distilled water to obtain an extract dispersant, extracting the extract dispersant sequentially with petroleum ether, ethyl acetate and n-butyl alcohol, and volatizing solvent to obtain a corydalis pygmaea petroleum ether part and a corydalis pygmaea ethyl acetate part; and concentrating and drying the extracted extract dispersant to obtain a corydalis pygmaea water-phase extraction part. The corydalis pygmaea effective part can be applied to preparation of medicines for inhibiting HDAC1 enzyme, and can be used for preparing anti-tumor medicines.
Owner:QINGHAI UNIV FOR NATITIES

Colla corii asini salmon caviar formula

A colla corii asini salmon caviar formula is formulated from salmon roes, calla corii asini, erilla frutescens, fermented soya beans, honey and oyster. The colla corii asini salmon caviar formula is formulated from natural ingredients, the colla corii asini salmon caviar is healthy and health-preserving, and has a clean mouthfeel. The caviar contains the skin's desired trace elements, mineral salts, protein, amino acids and restructuring basic fatty acids, and can effectively moisturize and nourish the skin, moreover, has effects of making the skin exquisite and smooth, while colla corii asini can replenish blood and nourish yin, moisten dryness and stop bleeding.
Owner:刘彬

Salmoncaviarrecipe

Provided is asalmon caviar formula. Salmon caviar is made from salmon roe, basil, ginger, hot pepper, cinnamon, cloves, garlic, Chinese prickly ash, honey and cooking wine, the salmon caviar formula consists of natural food materials through mixing, is healthy, preserves good health, has a fresh and cool taste, the salmon caviar containstrace elements, mineral salts, proteins, amino acids and essential restructured fatty acids required by the skin, can effectively moisturize the skin and can also make the skin tender, smooth and clean.
Owner:刘彬

Method for biologically converting silkworm excrement waste by utilizing fly maggots, and application of product of method

The invention discloses a method for biologically converting silkworm excrement waste by utilizing fly maggots, and application of a product of the method. The method comprises the following steps: breeding and domesticating fly species, pretreating the silkworm excrement waste, performing bioconversion treatment, and separating and applying the treated product. Compared with the prior art, the method has the following advantages: (1) the silkworm excrement waste is pretreated to adjust the water content of the silkworm excrement waste, so that normal growth and function exertion of fly maggots in the substrate are ensured; (2) the method effectively treats silkworm excrement by-product resources generated in the silkworm and mulberry industry, the obtained silkworm excrement conforms to the regulation of national standard organic fertilizer, efficient cyclic utilization of waste silkworm excrement can be realized, and waste is turned into wealth; and (3) the method utilizes fly maggots to efficiently convert silkworm excrement waste on a large scale, the treatment period is short and is far shorter than 16 days of composting with a microbial agent and 30 days of traditional composting, the conversion efficiency is high, the pollution is zero, the treatment is thorough, the industrial chain is long, and the economic, social and ecological benefits are remarkable.
Owner:JIANGSU UNIV OF SCI & TECH

Hawthorn fruit salmon caviar formula

The invention discloses a hawthorn fruit salmon caviar formula. The hawthorn fruit salmon caviar formula is prepared via blending of salmon, hawthorn fruit, purple perilla, sesame, tsaoko amomum fruit, clove, honey, and cooking wine. The hawthorn fruit salmon caviar formula is prepared via blending of the above natural food materials, is good for health, and is refreshing in mouthfeel; caviar contains trace elements, mineral salts, protein, amino acids, and recombinant essential fatty acids needed by the skin, so that caviar is capable of nourishing the skin effectively, and smoothening and brightening the skin; hawthorn fruit contains maslinic acid, vitamin C, saccharides, carotene, fat, protein, starch, calcium, and iron, and is capable of reducing blood pressure and blood lipid, strengthening heart, and promoting digestion.
Owner:刘彬

Tinospora-sinensis anti-HiV-1-virus effective part and preparing method and application

The invention discloses a tinospora-sinensis anti-HiV-1-virus effective part and a preparing method and an application, and belongs to the technical field of plant extract. The tinospora-sinensis anti-HiV-1-virus effective part is selected from a tinospora-sinensis acetic ether part or a tinospora-sinensis n-butyl alcohol part. The preparing method includes the steps that tinospora sinensis is smashed, 65%-95% by mass of an alcohol solution is added for extracting, the obtained extracted liquid is concentrated and dried, and extractum is obtained; the extractum is dispersed into distilled water, extractum dispersion liquid is obtained, then petroleum ether, acetic ether and n-butyl alcohol are used as a solvent respectively and used for extracting the extractum dispersion liquid, the obtained n-butyl alcohol extracted liquid is subjected to solvent volatilizing, and the tinospora-sinensis n-butyl alcohol part is obtained; the extracted residual extractum dispersion liquid is concentrated and dried, and a tinospora-sinensis aqueous-phase extracting part is obtained. An application of the tinospora-sinensis anti-HiV-1-virus effective part to preparing anti-HiV-1-virus medicine aspects is suitable for being developed into novel anti-AiDS medicine.
Owner:QINGHAI UNIV FOR NATITIES

Effective parts of skyblue adonis and preparation method and application thereof

The invention discloses the effective parts of skyblue adonis and the preparation method and application thereof and belongs to the technical field of plant extract. The method comprises of the steps of selecting the mixture of one or more than two extracts from the petroleum ether part, ethyl acetate, normal butyl alcohol part and water phase extraction part of skyblue adonis. Crushing the skyblue adonis and adding 65%-95% (weight) ethanol solution for extraction, concentrating and drying the extracting solution to obtain the extract; adding distilled water for dispersion to obtain extract dispersion, then respectively using petroleum ether, ethyl acetate and normal butyl alcohol as the solvent to extract the extract dispersion, making the solvent volatilize to obtain the petroleum ether part, ethyl acetate, normal butyl alcohol part and water phase extraction part of skyblue adonis; concentrating and drying the extracted extract dispersion to obtain the water phase extraction part of skyblue adonis. The effective parts of skyblue adonis of the invention can be used to prepare drugs inhibiting HDAC1 enzyme, and prepare cancer resistant drugs.
Owner:QINGHAI UNIV FOR NATITIES

Effective part of thick-stalk corydalis pallida and preparation method and application of effective part

The invention discloses an effective part of thick-stalk corydalis pallida and a preparation method and application of the effective part, and belongs to the technical field of plant extract. The effective part is selected from the mixture of one or two or more of a thick-stalk corydalis pallida ethyl acetate part, a thick-stalk corydalis pallida n-butyl alcohol part and a thick-stalk corydalis pallida water phase extraction part in any mass ratio. The preparation method comprises the steps that whole thick-stalk corydalis pallida is smashed, an ethanol solution with the volume percentage concentration of 65-95% is added for reflux extraction, and the obtained extracting solution is concentrated and dried to obtain extract; distilled water is added in the extract for dispersion, extract dispersing liquid is obtained, petroleum ether, ethyl acetate and n-butyl alcohol are used as solvents in sequence for extracting the extract dispersing liquid, a solvent is volatilized away, and the thick-stalk corydalis pallida ethyl acetate part and the thick-stalk corydalis pallida n-butyl alcohol part are obtained; the extracted extract dispersing liquid is concentrated and dried to obtain the thick-stalk corydalis pallida water phase extraction part. The effective part of the thick-stalk corydalis pallida is applied in preparation of medicine for inhibiting CDC25 enzyme and can be used for preparing anti-tumor medicine.
Owner:QINGHAI UNIV FOR NATITIES

Pilose deer horn salmon caviar recipe

The invention relates to a pilose deer horn salmon caviar recipe, which is prepared from salmon roe, pilose deer horn, tomato sauce, chopped chilli, cinnamon, five spice powder, honey and cooking wine through blending. The pilose deer horn salmon caviar recipe is blended by natural ingredients, and is health and fresh in taste; caviar contains microelements, mineral salt, proteins, amino acid and restructuring basic fatty acid required by skins, and not only can effectively moisten and nourish the skins but also has a function on enabling the skins to be fine and smooth; the pilose deer horn contains phospholipid, glycolipid, glue fat, hormone, fatty acid, amino acid, protein and elements such as calcium, phosphorus, magnesium and sodium; the amino acid element accounts for more than half of the overall element; the pilose deer horn is warm in nature but not dry, can inspire and improve body functions, and has a better body-building function for patients with general debility after long illness.
Owner:刘彬

Truffle salmon caviar formulation

The invention discloses a truffle salmon caviar formulation. The truffle salmon caviar formulation comprises salmon roes, truffle, perilla frutescens, illicium verum, cinnamon, clove, honey and cooking wine. The truffle salmon caviar formulation with natural food materials is healthy and refreshing to eat; caviar which contains trace elements, mineral salts, proteins, amino acids and recombinant elementary fatty acids needed by skin is not only capable of effectively nourishing skin but also capable of making skin smooth and clean. The truffle has extremely high nutrition and healthcare values and remarkable efficacies of Yang invigorating and internal secretion regulating, functions of immunity improving, senescence resisting, fatigue resisting and the like are achieved, and application to healthcare is realized.
Owner:刘彬

Effective part of corydalis hendersonii and preparation method and application of effective part of corydalis hendersonii

The invention belongs to the technical field of plant extracts and discloses an effective part of corydalis hendersonii and a preparation method and application of the effective part of corydalis hendersonii. The effective part of corydalis hendersonii is a mixture of one or more than two of an ethyl acetate part of corydalis hendersonii, an n-butyl alcohol part of corydalis hendersonii and an aqueous-phase extract part of corydalis hendersonii according to any mass ratio. The preparation method includes: grinding whole herbs of corydalis hendersonii, adding ethanol solution being 65%-95% in volume percent concentration to perform reflux extraction, and concentrating and drying extract liquor to obtain extract; adding distilled water into the extract to disperse to obtain extract dispersion liquid, sequentially adopting petroleum ether, ethyl acetate and n-butyl alcohol as solvents to extract the extract dispersion liquid, and volatilizing to remove the solvents to obtain the ethyl acetate part of corydalis hendersonii and the n-butyl alcohol part of corydalis hendersonii; concentrating and drying the extracted extract dispersion liquid to obtain the aqueous-phase extract part of corydalis hendersonii. Application of the effective part of corydalis hendersonii to preparation of CDC25 enzyme inhibition medicines is available for preparation of antitumor medicines.
Owner:QINGHAI UNIV FOR NATITIES

Limonium franchetii antineoplastic active constituent extract and preparation method and application thereof

The invention discloses limonium franchetii antineoplastic active constituent extract and a preparation method and application thereof. According to the limonium franchetii antineoplastic active constituent extract, after alcohol extraction is carried out on limonium franchetii, four kinds of active extract including cyclohexane, ethyl acetate, n-butyl alcohol and water are obtained. The active extract of the limonium franchetii can restrain proliferation of various cancer cell strains, the restraining effect is remarkable especially for leukemia cells HL-60 and K562, breast cancer cells MCF-7, lung cancer cells A549, cervical cancer cells Hela, liver cancer cells HepG-2 and other tumor cell strains, the antineoplastic activity of the ethyl acetate extract is most obvious, the anticancer spectrum is wide, the limonium franchetii active extract has the effect of inducing differentiation of the leukemia cells HL-60, and therefore the limonium franchetii antineoplastic active constituent extract can be used for preparation and development of antineoplastic drugs and has important significance especially for treatment researches of leukemia.
Owner:SHANDONG JINZHUJI PHARM CO LTD +1

The effective site, preparation method and application of Cerulea broadensis for inhibiting hdac1 enzyme

The invention discloses a tinospora sinensis HDAC1 enzyme inhibition effective part, as well as a preparation method and application thereof, and belongs to the technical field of plant extracts. The corydalis pygmaea effective part is one of a corydalis pygmaea petroleum ether part and a corydalis pygmaea aqueous extraction part, or a mixture of more than two of a corydalis pygmaea petroleum ether part, a corydalis pygmaea ethyl acetate part, a corydalis pygmaea n-butyl alcohol part and a corydalis pygmaea aqueous extraction part in an arbitrary mass ratio. The preparation method comprises the following steps of: grinding corydalis pygmaea, refluxing and extracting with an ethanol solution having a volume percentage concentration of 65-95 percent, concentrating and drying the extract to obtain an extract; dispersing the extract with distilled water to obtain an extract dispersant, extracting the extract dispersant sequentially with petroleum ether, ethyl acetate and n-butyl alcohol, and volatilizing a solvent to obtain a corydalis pygmaea petroleum ether part, a corydalis pygmaea ethyl acetate part and a corydalis pygmaea n-butyl alcohol part; and concentrating and drying the extracted extract dispersant to obtain a corydalis pygmaea water-phase extraction part. The corydalis pygmaea HDAC1 enzyme inhibition effective part can be applied to preparation of medicines for inhibiting HDAC1 enzyme, and can be used for preparing anti-tumor medicines.
Owner:QINGHAI UNIV FOR NATITIES

Poria cocos and salmoncaviarrecipe

Provided is a poria cocos and salmoncaviarrecipe. Poria cocos and salmoncaviar is made by deploying salmon roes, poria cocos, curry, sesame, amomum tsao-ko, clove, oyster sauce and cooking wine, the poria cocos and salmoncaviarrecipe adopts natural food materials for deploying, is healthy and health-care and has a fresh and cool taste, the salmoncaviar contains trace elements, mineral salts, proteins, amino acids and essential restructured fatty acids required by the skin, can effectively moisturize the skin, can also make the skin tender, bright and clean, and the poria cocos contains pachyman, pachymic acid, fatty acid, lecithin, adenine, protease and triterpene substances and also contains potassium, calcium, magnesium, phosphorus, iron, sulfur, silica minerals and other mineral substances.
Owner:刘彬

Method for preparing fused mullite from bauxite under coal

The invention provides a method for preparing electro-fused mullite from bauxite under coal, which comprises the following steps: grading the bauxite under coal, and removing silt; obtaining + d-grade minerals, and carrying out iron removal and desulfurization on the + d-grade minerals by adopting an X-ray concentrating machine to obtain intermediate minerals; calcining the intermediate mineral to obtain bauxite clinker; the preparation method comprises the following steps: crushing bauxite clinker, adding auxiliary materials, and uniformly mixing to obtain a mixture; melting the mixture in an electric arc furnace at a high temperature, cooling and crystallizing, and then crushing, grading and deironing to obtain a mullite product. According to the method, the under-coal bauxite is adopted as the main raw material to produce the fused mullite, the content of mullite phases in the mullite product is 95% or above, the comprehensive utilization rate of under-coal aluminum resources and the added value of the product are increased, the channel of the mullite raw material is widened, and sustainable high-quality development of the refractory material industry is powerfully supported.
Owner:ZHENGZHOU MINERALS COMPOSITIVE UTILIZATION RES INST CHINESE GEOLOGICAL ACAD

Yantai Limonium Limonium Antitumor Effective Component Extract, Its Preparation Method and Application

The invention discloses limonium franchetii antineoplastic active constituent extract and a preparation method and application thereof. According to the limonium franchetii antineoplastic active constituent extract, after alcohol extraction is carried out on limonium franchetii, four kinds of active extract including cyclohexane, ethyl acetate, n-butyl alcohol and water are obtained. The active extract of the limonium franchetii can restrain proliferation of various cancer cell strains, the restraining effect is remarkable especially for leukemia cells HL-60 and K562, breast cancer cells MCF-7, lung cancer cells A549, cervical cancer cells Hela, liver cancer cells HepG-2 and other tumor cell strains, the antineoplastic activity of the ethyl acetate extract is most obvious, the anticancer spectrum is wide, the limonium franchetii active extract has the effect of inducing differentiation of the leukemia cells HL-60, and therefore the limonium franchetii antineoplastic active constituent extract can be used for preparation and development of antineoplastic drugs and has important significance especially for treatment researches of leukemia.
Owner:SHANDONG JINZHUJI PHARM CO LTD +1

Extract of antineoplastic active components in vietnamese sophora root, and preparation method and application thereof

The invention discloses an extract of antineoplastic active components in a vietnamese sophora root and a preparation method thereof. The preparation method comprises the following steps: 1, successively carrying out extraction with water, condensation of extracted liquid, alcohol precipitation, centrifugation for removal of a precipitate and reduced pressure condensation for removal of ethanol so as to obtain extracted liquid, or successively carrying out heating extraction with 40 to 95% ethanol in a water-bath with a temperature of 80 DEG C, cooling, centrifugation and condensation for removal of ethanol so as to obtain the extracted liquid; and 2, extracting the extracted liquid with ethyl acetate, subjecting ethyl acetate extracted liquid to separation with a silica gel column, wherein eluents are dichloromethane-methanol with different volume ratios, collecting eluate obtained by using dichloromethane-methanol with a volume ratio of 50: 1 and recovering the organic solvent in the eluate so as to obtain the extract of the antineoplastic active components in the vietnamese sophora root. According to in vitro cytotoxicity experiments, the extract of the antineoplastic active components in the vietnamese sophora root has obvious inhibitory effects on U251 (glioma cells) and can be used for preparing antineoplastic drugs. The invention discloses the preparation method for the extract.
Owner:JIANGSU UNIV

Formula of goose liver-salmon caviar

The invention provides a formula of goose liver-salmon caviar. The goose liver-salmon caviar is made by blending salmon roes, goose livers, perilla leaves, round cardamom fruit, amomum tsao-ko, clove, honey and cooking wine. The goose liver-salmon caviar is made by blending the natural food materials, is healthy, capable of keeping health and fresh and cool in mouthfeel, contains trace elements, mineral salt, protein, amino acid and recombinant basic fatty acid which are needed by the skin and not only can effectively moisten the skin and enable the skin to obtain nutrients but also has the effects of enabling the skin to be fine, smooth, bright and clean, the goose livers are one of animal livers and have typical nutrient ingredients of the animal livers, and the livers are important organs for storing nutrients and removing toxicity in animal bodies, contain rich nutrient substances and are good blood replenishing products.
Owner:刘彬
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