44results about How to "Adjust physical and chemical properties" patented technology

The invention discloses a high-efficiency multi-bacterial activity biogas residue biofertilizer and a preparation method thereof, and relates to the field of farm fertilizers. The biofertilizer is prepared by mixing and granulating 44 to 54 weight parts of biogas residue, 10 to 15 weight parts of potassium chloride, 10 to 15 weight parts of humic acid, 0.4 to 0.6 part of secondary and micro-element, 0.4 to 0.6 weight part of microbe, 5 to 10 weight parts of urea, 10 to 15 weight parts of monoammonium phosphate and 5 to 10 weight parts of ammonium chloride. The high-efficiency multi-bacterial activity biogas residue biofertilizer has the characteristics of better multiple bacteria co-existing environment, stronger bioactivity, higher fertilizer efficiency, complete organic matters, effective micropopulations and chemical nutrients, controlled-release effect and the like, can be used as a fertilizer for rice, also can be used as a fertilizer for Upland food crops, vegetables, melons and fruits and fruit trees, and can improve the fertility of land and the utilization rate of the fertilizer, improve the quality of agricultural products, enhance plant diseases and insect pest resistance and drought resistance, purify and repair soil and the like after being applied.

The invention discloses a method for preparing a bioactive glass ceramic material for bone defect restoration, which comprises the steps of: sieving the biological glass powder, adding the polyacrylamide solution, ball milling and mixing uniformly to obtain the biological glass slurry; pouring the slurry into a macromolecular reverse mould by centrifugal grouting, curing, drying and sintering at a temperature of between 900 DEG C and 1000 DEG C controlled by a program to remove the macromolecular reverse mould to prepare the bioactive glass ceramic material for bone defect restoration. The shape of the bioactive glass ceramic material for bone defect restoration prepared by the invention can be decided according to clinical demand, and the bioactive glass ceramic material for bone defect restoration has good mechanical strength, biocompatibility and degradability, high compression strength, good anti-dispersion performance and activity and adjustable and controllable degradation time. The preparation method provided by the invention has a simple process and low cost.

The invention provides a soil improvement formula. The soil improvement formula comprises a soil conditioner, a microbial agent and biostimulant, the soil conditioner is prepared from kitchen organicwaste, and the microbial agent is prepared from 5 wt%-10 wt% of actinomycetes, 10 wt%-20 wt% of nitrogen-fixing bacteria, 5 wt%-10 wt% of paecilomyces lilacinus, 10 wt%-25 wt% of trichoderma viride, 5wt%-20 wt% of lactic acid bacteria and 20 wt%-35 wt% of bacillus subtilis. The biostimulant comprises seaweed extract and / or crustacean extract, wherein the mass ratio of the soil conditioner to themicrobial agent to the biostimulant is (300-800): (150-200): (60-120). According to the soil improvement formula, the secondary metabolism level of apples can be increased, and the external light color and flavor of fruits are improved. The invention further provides an application of the soil improvement formula in apple planting.

Currently, continuous reduction of soil fertility and serious salinization are caused by using a great deal of chemical fertilizer, meanwhile, necessary nutrient components in soil flow away along with water in the irrigation process when organic fertilizer is used to cause nutrition shortage, and consequently plant and crop growth is affected seriously. The invention discloses a slow release fertilizer production technology and a using method of slow release fertilizer, wherein the slow release fertilizer takes charcoal synthesized by biomass solid waste as the raw material and has the function of enriching nutrient elements, the method can be used for effectively adjusting the pH value of soil and improving the salinization current situation, soil fertility is improved, the application amount of chemical fertilizer is substantially reduced to conserve cultivated land, and sustainable utilization of cultivated land is achieved.

The invention relates to a preparation method of a coix seed extract. The method comprises the steps as follows: S1, drying and crushing coix seeds to obtain coix seed flour; S2, removing starch and fat in the coix seed flour through acid treatment and addition of a degreasing agent; S3, performing dynamic superhigh-pressure microfluidization treatment on coix seed pulp to promote dissolution extraction of polysaccharide and protein in the coix seed pulp; S4, adjusting the mass concentration of the coix seed pulp, adding an ionic strength regulator to regulate the ionic strength of the coix seed pulp, and adjusting the pH of the coix seed pulp; S5, adding an organic polymer adsorbent to the coix seed pulp to adsorb protein and polysaccharide agglomerates; S6, performing standing and filtration, collecting a filtered-out organic polymer adsorbent, and sequentially eluting polysaccharide and protein; and S7, removing starch and grease again through low-temperature settlement and centrifugal degreasing to finally prepare a coix seed emulsion containing polysaccharide and protein. The prepared coix seed emulsion is compounded into instant compound coix seed flour.

The invention discloses a special suspension liquid compound fertilizer for saline-alkali soil and a preparation method of the special suspension liquid compound fertilizer. The compound fertilizer comprises the following raw materials in parts by weight: 0.8-7.2 parts of a nitrogen fertilizer, 0.6-1.1 parts of a boric fertilizer, 0.5-0.8 part of EDTA-Zn, 0.5-0.8 part of EDTA-Mn, 2.0-5.0 parts of humic acid powder, 7.0-14.0 parts of a calcium fertilizer 8.0-16.0 parts of a phosphatic fertilizer, 5.0-9.0 parts of a potash fertilizer, 14.0-19.0 parts of an organic matter, 6.0-9.5 parts of a soil conditioner, 0.8-2.0 parts of a microbial agent, 2.0-4.0 parts of a wetting dispersant, 2.0-4.0 parts of an emulsifier, 1.0-3.0 parts of a thickener, 1.5-3.0 parts of an antifreezing agent and 23-30 parts of water. Through reasonable compounding of various nutritional ingredients, especially an efficient synergistic effect among the humic acid, the soil conditioner and the microbial agent, the physical and chemical properties of the soil are well adjusted, re-accumulation of saline matters is avoided, and nutrient elements required for growth and development are provided for crops, thus better growth of roots of the crop is facilitated, the yield and the quality of the crop are improved, and meanwhile, the element deficiency of the crop can be effectively prevented.

The invention belongs to the field of pharmaceutical chemistry, and particularly relates to pyridazinone compounds as shown in general formula I or isomers thereof or pharmaceutically acceptable salt, ester prodrug or solvate thereof, a preparation method thereof, a medicinal composition and application thereof in preparation of a tyrosine kinase inhibitor (especially c-Met inhibitor). The compounds or the medicinal composition thereof serving as a tyrosine kinase inhibitor (especially c-Met inhibitor) can be used for preventing and / or treating neoplastic diseases related to c-Met abnormality.

The invention relates to a composite microbial inoculant for degrading shale gas-water based drilling cutting pollutants as well as a preparation method and a use method of the composite microbial inoculant. A microbe main body of the composite microbial inoculant is prepared from pseudomonas aeruginosa, acinetobacter, bacillus subtilis and micrococcus which are mixed according to the mass ratio of (1-2) to (0.5-1) to (1-2) to (1-2), wherein the content of living bacteria number of the composite inoculant is 108-1,012 cfu / ml. The composite microbial inoculant can perform effective degradationon the shale gas-water based drilling cutting pollutants.

The invention discloses special complete-element biological slow release base fertilizer for cotton and a preparation method of the base fertilizer. The base fertilizer is prepared from raw materialsas follows: straw, livestock excrement, wood flour, waste animal protein, pecan shells, shells of bamboo shoots, functional bacteria, inorganic fertilizer and a coating solution. According to the special complete-element biological slow release base fertilizer for cotton and the preparation method of the base fertilizer, the base fertilizer has reasonable nutrient ratio, good slow release propertyand high fertilizer utilization rate, can effectively control black root rot of cotton, also can effectively adjust the physicochemical property of soil and effectively improves the quality of the cotton while increasing the yield of the cotton.

The invention provides a planting method for modifying desert wasteland. The method comprises the following steps: A) applying 300-600kg of a soil conditioner, 150-200kg of a special microbial fertilizer for saline-alkali soil and 3-5m < 3 > of decomposed farmyard manure to the surface of each mu of severe saline-alkali sandy land, wherein the special microbial fertilizer for saline-alkali soil isa microbial flora screened and separated from saline-alkali soil; B) performing rotary tillage on the sandy land for 10-15cm, and uniformly mixing the soil conditioner, the special microbial fertilizer for saline-alkali soil, the decomposed farmyard manure and surface sandy soil; and C) sowing mulberry root grass, and performing irrigation, wherein the mulberry root grass is annual multi-harvesting hybrid sudangrass. According to the method provided by the invention, rapid conservation is realized through a biological enhanced decomposition technology, and the physical and chemical propertiesof the soil are adjusted; and a sandy soil healthy ecological system is constructed through a microbial technology for resisting drought, salt and alkali and promoting plant growth in combination with a scientific farming technology, so that the growth of plant root systems is promoted, the tolerance of plants to drought and salt and alkali is increased, and the plant growth is increased.

The preparation process of cracking catalyst includes adding one additive selected from polyphosphate, phosphonate, polyamino carboxylate, homopolymer or copolymer with carboxyl chain segment into clay slurry and molecular sieve slurry, mixing with acidified adhesive slurry, and drying in conventional method or spraying drying. The said process has lowered material viscosity, raised solid content, flexible gluing mode, fastness, easy control, low power consumption and high production efficiency.

The invention discloses a bioactive soil conditioner for repairing chromium pollution of soil as well as a preparation method and application of the bioactive soil conditioner, and belongs to the technical field of soil pollution treatment. The bioactive soil conditioner is prepared from the following raw materials in parts by weight: 30-50 parts of humic acid, 15-25 parts of attapulgite, 15-20 parts of biogas residues, 10-15 parts of urea, 5-10 parts of a solid fermentation microbial agent, 1-3 parts of a stabilizer and 0.5-1.5 parts of ferrous sulfate. The bioactive soil conditioner disclosed by the invention can effectively reduce the content of hexavalent chromium in soil, increase the content of nutrient substances in the soil and regulate the physicochemical properties of the soil, and the compound use of microorganisms can improve the disease resistance of crops and improve the yield and quality of the crops while regulating the soil environment; and the bioactive soil conditioner is safe, environment-friendly, pollution-free, high in chromium removal efficiency, convenient to use and particularly suitable for treatment of chromium-polluted soil, and has wide economic benefits and social benefits.

The invention provides a method for preparing SnO2 / Ag2O composite particles through an electrostatic spinning method and a prepared product. The method comprises the following steps of dissolving tinsalt, didodecyldimethylammonium bromide, acetamide, silver nitrate and polyvinylpyrrolidone into a mixed solvent of dimethyl formamide and ethanol, stirring till the obtained mixture turns transparent, so as to obtain a precursor spinning solution, after carrying out electrostatic spinning and heat treatment, obtaining a final product. Through designing a novel precursor solution composition, thecrystallization and the growth process of two kinds of oxides in the high temperature sintering process are effectively controlled, the quasi-spherical SnO2 / Ag2O composite particles with adjustable size are obtained and has remarkable distinction with one-dimensional materials obtained by a traditional electrostatic spinning method. The method provided by the invention is simple and convenient inoperation in the synthetic process, controllable in product appearance, good in uniformity and high in yield, the prepared SnO2 / Ag2O composite material has better application to the field of gas sensitive sensors.

The invention provides a preparation method of an antibacterial preservative film loaded with nanoscale essential oil. The preparation method comprises the following steps: preparing an O / W type Pickering emulsion with high stability and high essential oil content from cyclodextrin, uniformly mixing the emulsion with a water-based chitosan film matrix, and preparing the antibacterial film with uniformly distributed essential oil through a tape casting method. The essential oil antibacterial film is uniform in texture, is colorless, semitransparent or yellowish and semitransparent according to the amount of essential oil, has certain mechanical properties, can be directly made into a film for use or used for coating the inner surface of a packaging material or the surface of food, can slowly release the antibacterial essential oil, is used for packaging food to achieve the purpose of prolonging the shelf life, and is a novel nano-antibacterial active packaging material for slow-release food.

The invention discloses a planting method for improving peony quality. The planting method comprises the following steps of S1, soil preparation and fertilizer applying: selecting sand soil, ploughingdeep, ridging and applying base fertilizer; S2, planting: selecting strong peony seedlings, soaking roots before planting, and watering after planting; S3, daily management: timely watering and draining, soil loosening, weeding, preventing and controlling diseases and pests, topdressing, pruning and disbudding. The planting method for improving peony quality improves stress resistance of peonies,promotes growth and development and accumulation of nutrient substances of peonies, and effectively improves yield and quality of peonies.

The invention provides a preparation method of a PLGA [poly(lactic-co-glycolic acid)] / bioactive glass composite degradable bone nail. The preparation method comprises the following steps: (1) dissolving polylactic acid-glycolic acid copolymer particles into an organic solvent to prepare an oil-phase solution of poly(light glycolic acid); (2) adding bioactive glass powder into the oil-phase solution to form a mixed emulsion of polylactic acid-glycolic acid copolymer / bioactive glass; (3) volatilizing the organic solvent in the mixed emulsion prepared in the step (2), washing with water, drying and placing the obtained powder in a discharge plasma sintering cavity for sintering. The biodegradable bone nail prepared by the method has high biocompatibility, high mechanical strength and high bioavailability. Through addition of the bioactive glass, an acidic environment generated in the degradation process of a polylactic acid-glycolic acid copolymer can be neutralized, so that the change ofpH value of the degradation solution of the polylactic acid-glycolic acid copolymer tends to be stable. The preparation method has the advantages of simple process, low cost and safer production industry.

The invention discloses a planting method for improving the survival rate of peony. The planting method comprises the following steps: S1, soil preparation and fertilization: selecting sandy soil, carrying out deep tillage and ridging, and applying a base fertilizer; S2, planting: selecting peony strong seedlings for planting, and carrying out thorough watering after the planting; S3, water and fertilizer management: timely carrying out watering and draining, and carrying out top dressing 2-4 times per year; and S4, prevention and control of diseases and insect pests: preventing and controlling diseases and insect pests of peony by chemical prevention and control and physical prevention and control. The planting method for improving the survival rate of the peony provided by the inventioncan effectively reduce the morbidity of peony diseases and insect pests, improve the survival rate of the peony, promote the growth and development of the peony, and improve the yield and the qualityof the peony.

The invention discloses a method for preparing chrysanthemum planting fertilizer by utilizing a rape seed cake and relates to the technical field of fertilizer production. The method for preparing the chrysanthemum planting fertilizer by utilizing the rape seed cake comprises the following steps: firstly sealing and fermenting the rape seed cake, grain stillage, dry feces of poultry and livestock, bitter gourd vines, rape stalks, brassica oleracea leaves and citric acid, so as to obtain a fermented material I, then mixing with bedding, shikimmi leaves, nettle, shepherd's purse and bean dregs, sealing and fermenting, so as to obtain a fermented material II, then preparing corncob, taro leaves, prepared rehmannia root, horseradish, kudzu vine powder, castor bean powder and seed powder of Chinese prickly ash into powder, and finally fully and uniformly mixing the fermented material II, the powder, sodium polyacrylate, zeolite powder and palm oil, so that the chrysanthemum planting fertilizer is obtained. The prepared chrysanthemum planting fertilizer contains abundant nutritional ingredients, is enough to supply of normal growth of chrysanthemum, lasting in fertility and high in utilization rate, has excellent insecticidal, bacterial, water-retaining and soil-loosening effects and can effectively kill toxic and harmful substances in soil to adjust the physical and chemical properties of the soil, so that the disease resistance of the chrysanthemum is improved, and the soil is protected.

The invention discloses black glass ceramic and a preparation method thereof. The ceramic is prepared from, by weight, 50-70 parts of mica powder, 12-25 parts of potassium permanganate, 5-16 parts of mica powder, 6-12 parts of blue vitriol, 4-14 parts of sodium silicate, 16-28 parts of silicon dioxide, 10-40 parts of zinc oxide and 3-10 parts of ammonium polyacrylate. The preparation method of the black glass ceramic comprises the steps of weighing raw materials according to the parts by weight, mixing and adding the raw materials into a crucible, heating the crucible, keeping temperature retention for 1-2 hours within the range from 1500 DEG C to 1600 DEG C, conducting shocking chilling, forming frit, smashing the frit into glass powder, placing the glass powder into a crucible at the temperature ranging from 1050 DEG C to 1100 DEG C for fusion, conducting natural cooling, and obtaining the black glass ceramic. According to the formula of the black glass ceramic, the mixing is conducted according to a certain proportion, then the black glass ceramic is obtained and is in black, products obtained after the mixing are stable in color and luster, little pollution is caused in the production process, only traditional ceramic firing equipment is needed for production, no additional dedicated electroplating equipment is needed, and the cost is saved.

The invention discloses a root-knot nematode control carbon-based medical fertilizer and a preparation method thereof. The carbon-based medical fertilizer comprises lythidathion, abamectin B2, wood vinegar, biomass charcoal, carrier fertilizers and adhesives. By applying the carbon-based medical fertilizer, soil diseases such as root-knot nematodes and bacterial wilt can be persistently and effectively controlled, the use ratio of the carrier fertilizers is increased, the physicochemical property of soil can be regulated, soil hardening is prevented, double pest control effects of fertilizer application and pesticide application can be simultaneously achieved by applying the medical fertilizer once, the disease resistance effect of vegetables can be remarkably enhanced, vegetable quality is improved, labor production efficiency can be improved, and the medical fertilizer plays a positive role in promoting production investment reduction and vegetable production and income increase.

The invention discloses high-strength impact-resistant glass ceramic and a preparation method thereof. The ceramic comprises the following raw materials in parts by weight: 50-70 parts of aluminum oxide, 12-25 parts of titanium dioxide, 5-16 parts of mica powder, 6-12 parts of sodium fluoride, 4-14 parts of sodium silicate, 16-28 parts of silicon dioxide, 10-40 parts of zinc oxide and 3-10 parts of ammonium polyacrylate. The preparation method comprises the following steps: weighing the raw materials in parts by weight, mixing the raw materials together, adding into a crucible, heating the crucible, keeping the temperature at 500-1600 DEG C for 1-2 hours, quenching to form frits, crushing into glass powder, melting the glass powder in a crucible at 1050-1100 DEG C, and naturally cooling. The high-strength impact-resistant glass ceramic disclosed by the invention is good in strength and difficult to break; and compared with the prior art, the preparation method disclosed by the invention needs a short time and is low in energy consumption and the product is good in quality and does not have toxic and harmful matter residues.

The invention relates to nark glaze, a bark glaze ceramic product prepared from the bark glaze and a preparation method of the bark glaze ceramic product, which belong to the technical field of ceramics. The bark glaze comprises the following raw materials in parts by weight: 35-37 parts of potash feldspar, 18-21 parts of barium carbonate, 14-17 parts of dolomite, 9-12 parts of calcium carbonate, 16-18 parts of bone ash and 4-5 parts of a chromogenic reagent, wherein the chromogenic reagent is a mixture of ferric oxide and manganese oxide at a mass ratio of 3:2. The preparation method comprises the following steps: according to the formula, mixing the raw materials and ball-milling; mixing to obtain glaze slip with required concentration; glazing and sintering, so as to obtain the bark glaze ceramic product. In the invention, through the reasonable formula and the simple preparation method, the bark glaze ceramic product returns to nature, is attractive in glaze and is environment-friendly, and energy conservation and emission reduction are achieved.

The invention provides a production method for basalt fibers by adopting modified basalt. The method comprises the steps that basalt particles are taken as the main material, water glass prepared through the mode that water is added to sodium silicate powder is taken as an adhesive, auxiliary materials uniformly adhere to the outer surfaces of the basalt particles, so that the auxiliary materialsand the basalt particles are pasted integrally, the phenomena of falling off and layering do not occur, and therefore the basalt is uniformly mixed with the auxiliary materials used for modification,which is beneficial for uniform treatment for the auxiliary materials and stable production of a kiln; the basalt and the auxiliary materials do not need to be ground into powder, the production costis reduced, the severe dust pollution problem existing in the processes of transportation, mixing and stirring, feeding and the like of large-tonnage basalt powder and auxiliary material powder is solved, and the effects of adjusting physical and chemical properties of the natural basalt and stabilizing basalt fiber production are achieved.

The invention discloses a suspension liquid set fertilizer for reducing yellowing of honey pomelo leaves and a preparation and application method thereof. The suspension liquid set fertilizer is composed of a suspension liquid fertilizer a and a suspension liquid fertilizer b; according to the suspension liquid fertilizer a and the suspension liquid fertilizer b, a phosphate fertilizer and calciumand magnesium fertilizers are separately prepared so that the phosphate fertilizer and other raw materials can be prevented from a drastic exothermic action, and the best use effect can be achieved.The set fertilizer can not only meet the nutrient requirements of fruit trees in different growth stages, but also obviously alleviate the yellowing symptom of the fruit trees; finally, the yield of the fruit trees is increased, the quality of the fruit trees is improved, and therefore the economic benefits are increased.

The invention relates to a preparation method of poly-amino acid-based triblock copolymer gel, belonging to the technical field of chemical engineering and comprising the following steps: preparing amino-terminated polyethylene glycol macromolecules through alkynyl-terminated polyamide-amine by a click chemistry method; inducing the ring opening polymerization of Gamma-benzyl-L-glutamic acid-N-carboxylic acid anhydride through the amino-terminated polyethylene glycol macromolecules obtained in the first step and preparing a poly (L-benzyl-glutamate)-polyethylene glycol-poly (L-benzyl-glutamate) triblock copolymer; and dissolving the poly (L-benzyl-glutamate)-polyethylene glycol-poly (L-benzyl-glutamate) triblock copolymer obtained in the second step into toluene, heating, stirring, cooling and standing to obtain the gel. The invention forms the symmetrical sector-linear-sector poly-amino acid-based triblock copolymer gel with different topological structures, thereby conveniently adjusting physical and chemical properties of the poly-amino acid-based gel through the topological structures of the macromolecules and the length of the support arms of the copolymer.

The invention discloses a saline and alkaline land soil conditioner prepared from bamboo vinegar and relates to the technical field of agricultural planting. The soil conditioner is prepared from raw materials in parts by weight as follows: 13-18 parts of the bamboo vinegar, 30-40 parts of corncobs, 15-20 parts of coconut dust, 15-20 parts of hawthorn leaves, 15-20 parts of leaves of illicium anisatum, 10-15 parts of Chinese arborvitae twigs and leaves, 10-15 parts of leaves of toona sinensis, 8-12 parts of Chinese honeylocust spines, 6-10 parts of bean dregs, 5-8 parts of peptone, 5-8 parts of mineral powder, 4-7 parts of distiller's yeast, 3-5 parts of yeast powder, 3-5 parts of tobacco straw ash and 2-4 parts of grape seed meal. The soil conditioner can reduce the pH value of soil, enrich nutritional ingredients of the soil, adjust physical and chemical properties of the soil and loosen the soil structure, besides, the added mineral powder can play a role in effectively killing bacteria and pests of the soil, treatment of the soil is simplified, so that plant growth is facilitated, and the planting workload is reduced.

The invention discloses a high-efficiency multi-bacterial activity biogas residue biofertilizer and a preparation method thereof, and relates to the field of farm fertilizers. The biofertilizer is prepared by mixing and granulating 44 to 54 weight parts of biogas residue, 10 to 15 weight parts of potassium chloride, 10 to 15 weight parts of humic acid, 0.4 to 0.6 part of secondary and micro-element, 0.4 to 0.6 weight part of microbe, 5 to 10 weight parts of urea, 10 to 15 weight parts of monoammonium phosphate and 5 to 10 weight parts of ammonium chloride. The high-efficiency multi-bacterial activity biogas residue biofertilizer has the characteristics of better multiple bacteria co-existing environment, stronger bioactivity, higher fertilizer efficiency, complete organic matters, effective micropopulations and chemical nutrients, controlled-release effect and the like, can be used as a fertilizer for rice, also can be used as a fertilizer for Upland food crops, vegetables, melons and fruits and fruit trees, and can improve the fertility of land and the utilization rate of the fertilizer, improve the quality of agricultural products, enhance plant diseases and insect pest resistance and drought resistance, purify and repair soil and the like after being applied.

The invention discloses an alkaline weld backing material. The finished alkaline weld backing material comprises the following components in percentage by weight: 40-75% of MgO and / or CaO, 15-40% of SiO2, 0-25% of Al2O3, 0-3% of Fe2O3 and 0.5-4% of Na2O and / or K2O; the alkalinity of the alkaline weld backing material is greater than 1. The alkaline weld backing material has the benefits that through a preferred material formula, the alkalinity of backing slag is controlled, the physicochemical property of the backing slag is adjusted, and the requirements on a high-strength high-toughness welding joint are met. Through the adoption of the backing material for welding, a formed welding seam is uniform and smooth no matter in a downward welding or vertical welding position. Compared with the conventional cordierite backing material, the mechanical properties, in particular to the low-temperature impact toughness, of the welding seam are remarkably improved. Besides, through the adjustment of the formula of the raw materials, the alkalinity of the backing slag is controlled, and different mechanical property requirements on the welding joints can be met.

The present invention is in the scope of the field of pharmaceutical chemistry. Specifically, the present invention relates to pyridazinone compounds of formula (I) or isomers, pharmaceutically acceptable salts, esters, prodrugs or solvates thereof, preparation method, pharmaceutical compositions thereof and use in manufacture of tyrosine kinase inhibitors, specially c-Met inhibitors. Said compounds or pharmaceutical compositions are used to prevent and / or treat tumor diseases related to c-Met abnormality as tyrosine kinase inhibitors, specially c-Met inhibitors.

The invention belongs to the technical field of organic fertilizers, and particularly relates to a microbial organic fertilizer which is prepared from the following raw materials in parts by weight: 200-250 parts of decomposed farmyard manure, 5-8 parts of a nitrogen-phosphorus-potassium compound fertilizer, 3-6 parts of a water-retaining agent, 0.03-0.06 part of a microbial agent and 30-50 parts of water. The invention also provides a production method of the microbial organic fertilizer. The microbial organic fertilizer can improve the water holding capacity of soil, save water and fertilizer, improve the utilization rate of water and fertilizer, and improve the properties of soil.