Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

31results about How to "Accurate aggregation" patented technology

Z axis elastic distance servo system used for laser processing

InactiveCN102179623AAchieving Elastic FloatingAvoid damageLaser beam welding apparatusLaser processingDrive motor
The invention discloses a Z axis elastic distance servo system used for laser processing, wherein a Z axis actuating mechanism is connected to a bracket; the bracket is provided with a fixed guiding sleeve and upper and lower limiting switches; a sliding guiding sleeve which can extend downwards is arranged in the fixed guiding sleeve; the lower end of the fixed guiding sleeve is provided with ananti-dropping cover; the lower end of the sliding guiding sleeve is provided with a connecting flange; a returning spring is arranged between the connecting flange and the anti-dropping cover; upper and lower limiting rods which are corresponding to the upper and lower limiting switches are arranged on the connecting flange; a laser head is fixed under the connecting flange and is aimed at a processed workpiece; a universal rolling ball head which can move on the surface of the processed workpiece is fixed under the connecting flange; and a constant vertical interval is kept between a light outlet of the laser head and the lower end of the universal rolling ball head. The Z axis elastic distance servo system can be used for realizing the elastic floatation of the laser head in a defined scope and realizing the quick ascending and descending of the laser head out of the preset scope by using the limiting switches to control a driving motor, thereby ensuring that the laser beam is focused on the surface of the processed workpiece all the time.
Owner:武汉工研光学科学技术股份有限公司

System and method for actively tracking solar radiation

The invention discloses a system and a method capable of automatically tracking solar radiation, which utilize local geographical information and time domain information, and interactions of the ecliptic plane, the equatorial plane and the horizontal plane to solve the problem of inaccurate tracking in different time domains, different latitudes and longitudes, areas in southern hemisphere and northern hemisphere and the like around the world. Moreover, the system can flexibly follow the direction of intense radiation according to local radiation conditions, and also can be changed into a dynamic sunlight tracking system used for mobile objects and devices to accurately track the sun according to time service information and positioning information emitted by a satellite.
Owner:李姝江

Smart city three-dimensional comprehensive command center

The invention provides a smart city three-dimensional comprehensive command center, which comprises a big data basic platform, big data sharing exchange cloud middleware and a three-dimensional visualcommand platform. The big data basic platform breaks an information island and timely and accurately gathers service source data of at least one service system of each unit in a plurality of units. The big data sharing exchange cloud middleware is used for cleaning, storing, extracting, analyzing, calculating and the like of tens of millions of levels of business source data, and data services related to various business functions can be provided. Moreover, three-dimensional modeling is carried out on the city by using a three-dimensional visual command platform. A three-dimensional portraitof a city is drawn, comprehensive commanders can acquire and consult data related to any business function based on the three-dimensional visual commanding platform around the city event, so that comprehensive information related to the city event is acquired, and comprehensive scheduling and decision making are carried out based on the comprehensive information related to the city event.
Owner:北京畅春互联科技有限公司

Three-dimensional face expression recognition method based on SSF-IL-CNN

The invention discloses a three-dimensional face expression recognition method based on an SSF-IL-CNN. According to the method, firstly, a convolutional neural network structure is improved, a convolutional kernel is disassembled into the structure parameters and the strength parameters, and the two parameters are enabled to respectively undertake the initialization and updating tasks, so that theconvolutional neural network originally needing a large number of samples for training can be applied to a three-dimensional facial expression library with a small sample scale. Meanwhile, accordingto the method, an Island Loss function is adopted to construct a loss function in the convolutional neural network, the sensitivity and the distinction degree of the network to the facial expressionsare enhanced, and the expression recognition effect is improved.
Owner:SOUTHEAST UNIV

Network video event mining framework based on dynamic association rules

InactiveCN103440248AReduce the impactGood Word Semantic Relationship CombinationSpecial data processing applicationsMachine learningEvent mining
The invention discloses a network video event mining framework based on dynamic association rules. Aiming at the characteristics of little information, much noise and the like of network video text information, by using semantic information among keywords and by dynamically adjusting the support degree in the association rules, influences on the relation between text and visual information caused by problems of noise, synonyms, polysemous words, multiple languages and the like are reduced, the robustness of text information is enhanced, and a bridge between visually approximate key frames and high-level semantics is established. The network video event mining framework based on dynamic association rules fully utilizes the semantic correlation among the text information and the relation between the text information and the visual information, the influences of noises in the text information on the relation between the visually approximate key frames and events are reduced, the correlation between the visually approximate key frames and the corresponding events is enhanced, and the framework is enabled to better adapt to event mining of network videos with much noise and little information.
Owner:SOUTHWEST JIAOTONG UNIV

An infrared image volume cloud detection method based on neighborhood intensity texture coding

The invention discloses an infrared image volume cloud detection method based on neighborhood intensity texture coding. The invention relates to the technical field of infrared image processing. The method comprises the following steps: firstly, creating a sliding window to traverse infrared image pixel points; performing texture coding on the infrared image by using a neighborhood intensity coding method to generate a texture image, roughly determining coordinates of a suspected point region based on local probability distribution, then using region growth to aggregate false alarm source pixels, and finally performing denoising by using a neighborhood statistical method to finally obtain a detection result. According to the method, the problems of difficulty in accurately detecting the volume cloud, low detection precision and fuzzy detection result in the existing infrared imaging technology are solved, and the method has the advantage of accurately aggregating the false alarm sourcepixel region.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Method and system for validation of merchant aggregation

A method and system that involve retrieving, from one or more databases, a first set of information including merchant aggregated payment card transaction data for a defined time period, and retrieving, from one or more databases, a second set of information including merchant reported sales data for the defined time period. The method and system further involve analyzing the first set of information and the second set of information to generate a correlation coefficient for the defined time period, and assessing the merchant aggregated payment card transaction data based on the correlation coefficient. The method and system enable validation or verification of merchant aggregation, e.g., determining if merchant aggregation is optimal or above a predetermined threshold value. The method and system leverage consumer payment transaction data and merchant sales information in a way so as to enable validation or verification of merchant aggregation.
Owner:MASTERCARD INT INC

An infrared imaging river channel detection method based on neighborhood intensity texture coding

The invention discloses an infrared imaging river channel detection method based on neighborhood intensity texture coding. The invention relates to the technical field of infrared image processing. The method comprises the following steps of: performing texture coding on an input image by using a neighborhood intensity coding method; generating a texture image, roughly determining coordinates of asuspected point region based on local probability distribution, generating a preliminary detection result by using region growth, neighborhood statistical denoising and other methods, detecting a connected region of the preliminary detection result, taking gradient features of the input image, and performing region growth to finally obtain a detection result. According to the method, the problemsthat the riverway is difficult to accurately detect, the detection precision is low and the detection result is fuzzy in the existing infrared imaging technology are solved, and the method has the advantage of accurately aggregating the false alarm source pixel region.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Display device and method for implementing holographic display thereof

The invention discloses a display device and a method for implementing holographic display thereof. A plurality of first lenses closely arranged in an array manner constitute a first lens array, and each of the first lenses corresponds to a plurality of observation regions arranged on a light outgoing path respectively; a plurality of slits arranged in an array manner and corresponding to the first lens one by one constitute a slit array; a spatial light modulator loads a holographic image; a human eye tracking device tracks the position of human eyes; a controller determines an observation region according to the position of the human eyes, then controls a deflection element to direct the exit light of the spatial light modulator to the slit corresponding to the first lens corresponding to the observation region, and controls the deflection angle of the first lens to converge the exit light of the first lens to the position of the human eyes. Because the controller can control the deflection of different angles of the first lenses according to the position of the human eyes, the holographic image can be accurately converged at the position of the human eyes, thereby overcoming theproblem that the viewing angle is limited in the holographic window technology.
Owner:BOE TECH GRP CO LTD

Center calibration device of laser coupling table

ActiveCN113467015AAvoid the problem of looseness affecting the coupling effectAvoid restrictionsCoupling light guidesDirect couplingErbium lasers
The invention discloses a center calibration device for a laser coupling table, which comprises a coupling table, a coupling hole is formed in the coupling table, the coupling hole penetrates through the coupling table, a laser is fixedly arranged on one side of the coupling table through a fixing mechanism, and the laser is fixedly arranged on the other side of the coupling table through the fixing mechanism. A coupling hole is formed in the coupling table, the output end of the laser corresponds to the coupling hole, two extension plates are fixedly arranged on the side wall of the side, away from the laser, of the coupling table, the two extension plates are symmetrically arranged on the two sides of the coupling hole, and two insertion grooves corresponding to the extension plates are symmetrically formed in the coupling table; and clamping mechanisms corresponding to the extension plates are arranged in the two slots. According to the invention, the laser and the optical fiber can be rapidly fixed and calibrated, the coupling efficiency is greatly improved, rapid conversion of direct coupling or lens coupling can be carried out according to needs, the coupling device does not need to be replaced, and the adaptability of the device is greatly improved.
Owner:XINJIANG NORMAL UNIVERSITY

Novel multi-channel handheld SPR detector

The invention discloses a novel multi-channel handheld SPR detector. The novel multi-channel handheld SPR detector comprises a casing; a light incidence assembly, alight reflection assembly and a light reception assembly are sequentially clamped in a light incidence assembly accommodating cavity, a light reflection assembly accommodating cavity and a light reception assembly capacity; a sensing chip comprises a substrate and a gold-plated glass piece; sensing chip guiderails are symmetrically arranged on the inner surfaces of the front and rear sides of the casing; sensing chip brackets are glidingly arranged on the sensing chip guiderails; sensing chips are arranged in the sensing chip brackets; and injection port sealing and connection devices and extraction port sealing and connection devices are respectively arranged at positions, corresponding to a plurality of sample storage grooves and sample recovery grooves, on the surface of the casing. The novel multi-channel handheld SPR detector is capable of directly extracting a plurality of liquid samples from a sample storage vessel at one time without dripping the liquid samples into a loading slot after taking the sensing chips in exposed environment, thereby preventing the liquid samples from being polluted and then improving the detection correctness.
Owner:ZHEJIANG POLICE COLLEGE

Household appliance having a collecting apparatus for leakage water

The invention relates to a household appliance (1) for the care of laundry items, having a collecting apparatus (5) for leakage water which is arranged on the base (4) of the household appliance (1), and a float (81) which is arranged in the collecting apparatus (5) and is configured for making electrical contact with a switch (8) as a function of the water level (W) in the collecting apparatus (5), wherein the float (81) is arranged in a first part region (5a) of the collecting apparatus (5), which first part region (5a) is separated from a second part region (5b) of the collecting apparatus (5) by a water damming wall (52).
Owner:BSH BOSCH & SIEMENS HAUSGERAETE GMBH

Face recognition based control method of exhibition hall robot arm

The invention relates to a face recognition based control method of an exhibition hall robot arm. The control method is characterized in that a target face with the shortest physical distance to a lens of shooting equipment for the exhibition hall robot arm is accurately determined from a 360-degree panoramic image with a face feature algorithm, and then a target face is subjected to forward calculation by combining a face attribute algorithm, and attribute information of the target face is obtained; then, control materials such as height, actions and intonation adapted to the attribute information of the target face are generated for the exhibition hall robot arm, and the exhibition hall robot arm is correspondingly controlled according to the control materials. Thus, spatial pose changedisplay of the exhibition hall robot arm can be performed according to the control materials adapted to the attribute information of the target face when the presence of visitors in an exhibition hallarea is accurately identified, power consumption of the exhibition hall robot arm is reduced, and more people are attracted to the exhibition hall area; besides, accuracy of face detection can also be improved.
Owner:DONGGUAN HUARUI ELECTRONICS TECH CO LTD

A Method of Improving the Utilization Rate of Laser Deposition Powder

The invention relates to the technical field of laser additive manufacturing, and specifically discloses a method for improving the utilization rate of laser deposition powder. The method includes: pre-preparing a cladding layer with metal powder on one end of the surface of the substrate; performing magnetization treatment on the substrate and the cladding layer to form a leakage magnetic field; and performing the next pass of laser cladding under the action of the leakage magnetic field. The metal powder is ferromagnetic material or contains ferromagnetic material, and the base material is ferromagnetic material. The method provided by the invention uses the height difference between the cladding layer and the surface of the area to be deposited to magnetize the ferromagnetic substrate and the cladding layer to form a leakage magnetic field, which has a good attraction effect on the ferromagnetic metal powder, making the nozzle The sent powder can be more accurately converged on the laser scanning path, improving the effective utilization rate and deposition efficiency of the powder.
Owner:SHIJIAZHUANG TIEDAO UNIV

Novel handheld SPR detector

The invention discloses a novel handheld SPR detector which comprises a shell, wherein a light incidence assembly, a light reflection assembly and a light receiving assembly are sequentially clamped in a light incidence assembly accommodating cavity, a light reflection assembly accommodating cavity and a light receiving assembly accommodating cavity; the sensing chip comprises a substrate and a gold-plated glass sheet; the surface of the movable cover plate is provided with a sample injection port and a sample extraction port at positions corresponding to a sample storage tank and a sample recovery tank respectively, and after the movable cover plate is closed, the sample injection port is in sealed communication with the sample storage tank through an injection port sealing connection device, and the sample extraction port is in sealed communication with a sample recovery tank through the extraction port sealing connection device. The invention aims to provide a novel handheld SPR detector, which can directly extract a liquid sample from a sample storage vessel without dropping the liquid sample into a sample adding slot after the sensing chip is taken out from an exposed environment, thereby avoiding the pollution of the liquid sample and improving the detection accuracy.
Owner:ZHEJIANG POLICE COLLEGE

Purpose of immunological nanoparticles of brucine in preparing anti-hepatoma target drugs

The invention relates to a purpose of immunological nanoparticles of brucine in preparing anti-hepatoma target drugs. The immunological nanoparticles of brucine are immunological target nanoparticles which treat brucine as an active component and a carboxylated polyethylene glycol-polylactic acid segmented copolymer as a drug coating accessory, and are formed by externally linking with anti-humanAFP monoclonal antibodies. The immunological nanoparticles of brucine provided by the invention, which have the characteristics of simple technology, high entrapment rate, stable drug release, and good balling, can be used for preparing antitumor target drugs which can be used for anti-hepatoma treatment. By intravenous injection, a nanometer carrier anti-human AFPMcAb-polyethylene glycol-polylactic acid segmented copolymer allows brucine aggregation in hepatoma cells to be increased, the drugs to be slowly and locally released, the effect time of the drugs to tumor cells to be prolonged, thelocal drug concentration to be improved, and the whole body toxicity of brucine to be reduced. So the immunological nanoparticles of brucine of the present invention have the advantages of accurate aggregation of target drugs in the cells of tumor tissues, stable drug release, good anticancer effect, safety and the like.
Owner:SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL +2

Method and device for determining semantic similarity of text based on graph data

The embodiment of this specification provides the concept of using graph data to determine the semantic similarity of text. Under this technical concept, the nodes in the graph data correspond to the sentences and words in the corpus, and the associated sentences and words, words and words are connected by Connection edges are connected, and each node corresponds to a node expression vector that can express the semantic information of the corresponding word or sentence. In the data preprocessing process of graph data, a large amount of unsupervised data can be used to construct graph data to describe the relationship between words and sentences, and words and words, and the model parameters of the processing model can be optimized through a small amount of supervised data to make similar Vector representations of text can interact with each other, enabling efficient vector representation of text and vocabulary through graph data. When determining the semantic similarity of the text, the vector of the text to be determined semantic similarity is obtained through the graph data, and the semantic similarity of the text is determined using the vector similarity. In this way, the generality, accuracy and effectiveness of text semantic similarity can be improved.
Owner:ALIPAY (HANGZHOU) INFORMATION TECH CO LTD

Flexible optoelectronic thin membrane and manufacturing method thereof

A method for forming a flexible photoelectric thin film, the method includes: providing a first substrate, wherein a conductive layer is provided on the first substrate. Afterwards, a first positioning structure is formed on the conductive layer, wherein the first positioning structure includes a plurality of first target areas and a plurality of first peripheral areas located around the first target areas, and the surface tension of the first target areas is Different from the surface tension of the first peripheral zone. Next, an electro-optic medium placement process is performed to form electro-optic medium droplets on each of the first target areas. Next, a curing process is performed to respectively form a film wall covering each droplet of the first electro-optic medium. Finally, pressing the first substrate and the second substrate.
Owner:IRIS OPTRONICS INC

A method, device, medium and electronic equipment for obtaining memory leak information

The disclosure provides a method, device, medium and electronic equipment for acquiring memory leak information. The method includes: the main process obtains its abnormal crash information; based on the triggering of the abnormal crash information, the main process creates and runs an emergency sub-process; the emergency sub-process obtains the memory state information shared by the main process, and saves it in the memory state Data collection; when the main process runs again, obtain memory state information from the memory state data set; when the memory state information meets the memory exception condition, the main process generates memory leak information. The disclosure directly acquires the size information of the virtual memory, thereby quickly locating the memory leak information, and accurately aggregates the memory leak information, thereby improving the efficiency of locating program faults. Creating a copy-on-write subprocess reduces the interference of other threads and / or processes, avoids interrupting the exception handling process, and improves the success rate and stability of obtaining exception information.
Owner:BEIJING BYTEDANCE NETWORK TECH CO LTD

Inner hole laser cladding height control system and method

The invention discloses an inner hole laser cladding height control system. The inner hole laser cladding height control system comprises a control system body and an inner hole cladding head. For aninner hole laser cladding height control method, a space right-angle coordinate system is built, an indication light beam deviates towards the laser scanning direction by the proper distance, the actual deviation amount of light spots of the indication light beam relative to a molten pool is obtained in a CCD image, according to the mathematic relation between the deviation distance of the light spots of the indication light beam and the deviation distance of the workpiece surface, the deviation between the actual distance of the inner hole cladding head and the workpiece surface and the standard distance is obtained through calculation, and the inner hole cladding head is controlled to be subjected to height adjusting. The inner hole machining head height is adjusted in real time, and therefore the distance between an inner hole machining head and the workpiece surface is kept constant, it is ensured that powder of a cladding head nozzle is gathered in the molten pool, the inner holecladding quality is improved, and the powder use rate is improved.
Owner:NANJING INST OF ADVANCED LASER TECH

System and method for actively tracking solar radiation

The invention discloses a system and a method capable of automatically tracking solar radiation, which utilize local geographical information and time domain information, and interactions of the ecliptic plane, the equatorial plane and the horizontal plane to solve the problem of inaccurate tracking in different time domains, different latitudes and longitudes, areas in southern hemisphere and northern hemisphere and the like around the world. Moreover, the system can flexibly follow the direction of intense radiation according to local radiation conditions, and also can be changed into a dynamic sunlight tracking system used for mobile objects and devices to accurately track the sun according to time service information and positioning information emitted by a satellite.
Owner:李姝江

Auxiliary positioning and screw placement device for proximal femoral intramedullary nail

The invention discloses an auxiliary positioning and screw placement device for a proximal femur intramedullary nail, which comprises an arc-shaped positioning through cylinder, a femur trochanter positioning needle, a first screw, a second screw and a working channel assembly, wherein the arc-shaped positioning through cylinder is of a quarter arc structure; a positioning needle channel is transversely formed in one end of the arc-shaped positioning through cylinder, the femoral trochanter positioning needle is movably inserted into the positioning needle channel through a first screw, and the needle point of the femoral trochanter positioning needle faces the circle center of the arc-shaped positioning through cylinder; the other end of the arc-shaped positioning through cylinder is provided with a threaded hole, the second screw is movably inserted into the threaded hole in the other end of the arc-shaped positioning through cylinder, and the working channel assembly is movably arranged at the other end of the arc-shaped positioning through cylinder through the second screw. The auxiliary positioning and nail placing device for the proximal femoral nail is simple in structure, accurate positioning can be achieved, and the perspective frequency is reduced.
Owner:中国人民解放军总医院第六医学中心

High-speed full-automatic grouping and track combining machine device

The invention relates to a high-speed full-automatic grouping and track combining machine device. The high-speed full-automatic grouping and track combining machine device is characterized by comprising a first grouping mechanism, a second grouping mechanism and a material combining mechanism; the first grouping mechanism comprises a first material guide frame, a first chain belt, a first drivingmotor, a first bearing belt and a plurality of first material distributing components; the first material guide frame is provided with a first material guide channel; the second grouping mechanism comprises a second material guide frame, a second chain belt, a second driving motor, a second supporting belt and a plurality of second material distributing components; the second material guide frameis provided with a second material guide channel; the material combining mechanism comprises a conveying belt, a first guide piece, a second guide piece and a third driving motor; the input end of theconveying belt is simultaneously connected with the first material guide channel and the second material guide channel. Grabbing and placing beverage bottles by workers can be completely avoided, thepackaging efficiency can be greatly improved by the high-speed full-automatic grouping and track combining machine device, the situation of packing errors can be avoided, the hygiene of the beveragebottles can be prevented from being affected, and the high-speed full-automatic grouping and track combining machine device is very reliable in overall structure.
Owner:YINGHUI PACKAGING MECHANICAL EQUIP

Household appliances with leak collecting devices

The invention relates to a household appliance (1) for caring for laundry, which has a water leakage collection device (5) arranged on the bottom (4) of the household appliance (1) and a water leakage collection device (5) arranged in the collection device (5). The float (81) makes electrical contact with the switch (8) according to the water level (W) in the collection device (5), wherein the float (81) is arranged in the first partition (5a) of the collection device (5) , the first partition is separated from the second partition (5b) of the collection device (5) by a water retaining wall (52).
Owner:BOSCH SIEMENS HAUSGERATE GMBH

Magnetic steering targeted therapy device

The invention discloses a magnetic steering targeted therapy device which comprises a base, a vertical main lifting rod, a transverse telescopic rod, a vertical auxiliary lifting rod and magnetic generation plates. The base is connected with the lower end of the vertical main lifting rod, the upper end of the vertical main lifting rod is connected with the left end of the transverse telescopic rod, the right end of the transverse telescopic rod is connected with the vertical auxiliary lifting rod, and the two ends of the vertical auxiliary lifting rod are each connected with one magnetic generation plate. The device is characterized in that a central controller is fixedly connected to the joint of the transverse telescopic rod and the vertical main lifting rod, and a transformer, a microprocessor chip and a memory are integrated and connected in the central controller; the right end of the transverse telescopic rod is connected with the middle of the vertical auxiliary lifting rod through a full-angle rotating shaft; the upper section and the lower section of the vertical auxiliary lifting rod can ascend and descend; and the distance between the two magnetic generation plates and the body surface and the magnetic force can be automatically controlled and adjusted, and through the series of automatic control and adjustment, medicine can be completely and accurately attracted to the focus position to act.
Owner:HUNAN PROVINCIAL TUMOR HOSPITAL

Z axis elastic distance servo system used for laser processing

InactiveCN102179623BAchieving Elastic FloatingAvoid damageLaser beam welding apparatusLaser processingDrive motor
The invention discloses a Z axis elastic distance servo system used for laser processing, wherein a Z axis actuating mechanism is connected to a bracket; the bracket is provided with a fixed guiding sleeve and upper and lower limiting switches; a sliding guiding sleeve which can extend downwards is arranged in the fixed guiding sleeve; the lower end of the fixed guiding sleeve is provided with an anti-dropping cover; the lower end of the sliding guiding sleeve is provided with a connecting flange; a returning spring is arranged between the connecting flange and the anti-dropping cover; upper and lower limiting rods which are corresponding to the upper and lower limiting switches are arranged on the connecting flange; a laser head is fixed under the connecting flange and is aimed at a processed workpiece; a universal rolling ball head which can move on the surface of the processed workpiece is fixed under the connecting flange; and a constant vertical interval is kept between a light outlet of the laser head and the lower end of the universal rolling ball head. The Z axis elastic distance servo system can be used for realizing the elastic floatation of the laser head in a defined scope and realizing the quick ascending and descending of the laser head out of the preset scope by using the limiting switches to control a driving motor, thereby ensuring that the laser beam is focused on the surface of the processed workpiece all the time.
Owner:武汉工研光学科学技术股份有限公司

An electron column using a magnetic lens layer

Disclosed herein is an electron column using a magnetic lens layer. The electron column includes a magnetic lens layer for condensing an electron beam using permanent magnets. The magnetic lens layer includes a support plate, an aperture formed through the support plate, and permanent magnets arranged around the aperture and disposed on or inserted into the support plate.
Owner:CEBT

Optical measuring method for in-plane vibration of micro-electromechanical structure

The invention discloses an optical measuring method for in-plane vibration of a micro-electromechanical structure, which belongs to the technical field of vibration measurement. Firstly, an optical measuring device is built and used for measuring the in-plane vibration of the micro-electromechanical structure, coherent parallel light irradiates a plane of a measured micro-electromechanical device through a beam splitter prism, reflected light on the plane is transmitted by the beam splitter prism to a score at the focus of a Fourier lens with optical Fourier characteristics, the spatial frequency spectrum of light intensity distribution of the reflected light on the plane of the micro-electromechanical device is formed, and the position and the vibration amplitude of the micro-electromechanical device are obtained by measuring the frequency of spectral line light intensity change in the spatial frequency spectrum and calculating Fourier transformation of spectral line light intensity. An optical path structure is simple, light beams do not need to be accurately gathered, and precise time synchronization technology is not needed. The requirements of large-scale assembly line production on product testing can be effectively met, and wide marketing and application prospects are realized.
Owner:TSINGHUA UNIV

Use of strychnine immune nanoparticles for preparing anti-liver cancer targeted drugs

The invention relates to a preparation method of strychnine immune nanoparticles, and the preparation method comprises the following specific steps: step 1, dissolving carboxylated poly(ethylene glycol)-polylactic acid block copolymer and strychnine in an organic solvent, and then mixing with a polyvinyl alcohol aqueous solution to form a primary emulsion; step 2, removing the organic solvent andimpurities to obtain a strychnine nanoparticle concentrate; and step 3, sequentially adding a carbodiimide salt used as a carboxyl activation reagent and an anti-human-AFP (alpha-fetoprotein) monoclonal antibody to the strychnine nanoparticle concentrate, thus linking the carboxyl group on polyethylene glycol and the amino group of the anti-human-AFP monoclonal antibody by chemical coupling to obtain the strychnine immune nanoparticles. The preparation method provided by the invention has the advantages of simple process, high encapsulation rate, stable drug release and good drug ballability;and the obtained strychnine immune nanoparticles are used for preparing anti-tumor immune targeting drugs, and have the advantages of precise targeting drug accumulation in tumor tissue cells, stabledrug release, good anti-cancer effect, safety and the like.
Owner:SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL +2
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products