Novel handheld SPR detector

Abstract

The invention discloses a novel handheld SPR detector which comprises a shell, wherein a light incidence assembly, a light reflection assembly and a light receiving assembly are sequentially clamped in a light incidence assembly accommodating cavity, a light reflection assembly accommodating cavity and a light receiving assembly accommodating cavity; the sensing chip comprises a substrate and a gold-plated glass sheet; the surface of the movable cover plate is provided with a sample injection port and a sample extraction port at positions corresponding to a sample storage tank and a sample recovery tank respectively, and after the movable cover plate is closed, the sample injection port is in sealed communication with the sample storage tank through an injection port sealing connection device, and the sample extraction port is in sealed communication with a sample recovery tank through the extraction port sealing connection device. The invention aims to provide a novel handheld SPR detector, which can directly extract a liquid sample from a sample storage vessel without dropping the liquid sample into a sample adding slot after the sensing chip is taken out from an exposed environment, thereby avoiding the pollution of the liquid sample and improving the detection accuracy.

Description

technical field [0001] The invention relates to a biological detection instrument, in particular to a novel hand-held SPR detection instrument. Background technique [0002] Surface plasmon resonance (SPR) is a physical optical phenomenon. At the interface of two transparent media with different refractive index (such as glass and water), when a beam of light is incident from a medium with a high refractive index to a medium with a low refractive index, the light will be refracted and reflected. When the incident angle increases to a certain value, the refraction angle is equal to 90°, and the light is emitted along the direction tangent to the interface. The incident angle at this time is called the critical angle. If the incident angle exceeds the critical angle, the incident light will not enter another medium, but all will be reflected back into the incident medium, and total internal reflection will occur. [0003] In fact, although all incident light is reflected, an...

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Problems solved by technology

[0006] In the above-mentioned patent, when adding the liquid sample to be tested, the sensor chip needs to be taken out, and the liquid sample to be tested is dropped into the sampling tank under the exposed environment, which is inconvenient to operate and will also cause contamination of the liquid sample to be tested

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